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$264+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$327
(Delta)

One-way from

$264
(American Airlines)

Popular in

June

Cheapest in

February

Average price

$762
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
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From Gainesville Regional to Iowa
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One-way flight from Gainesville Regional to Iowa
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Highest demand for flights based on searches. 12% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($62 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Gainesville to Iowa

Cheapest flights from Gainesville to Iowa
Explore the most affordable flight options available from Gainesville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:04 pmGNV - OMA
1 stop6h 10mDelta
Sun 11/235:55 pmOMA - GNV
1 stop4h 16mDelta
Deal found 11/3$455
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:59 pmGNV - OMA
1 stop6h 33mAmerican Airlines
Sun 11/236:00 amOMA - GNV
2 stops9h 21mAmerican Airlines
Deal found 11/3$464
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:00 amGNV - DSM
1 stop6h 42mAmerican Airlines
Mon 12/13:31 pmDSM - GNV
1 stop6h 34mAmerican Airlines
Deal found 11/4$496
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:04 pmGNV - MLI
1 stop4h 31mDelta
Sun 11/235:12 pmMLI - GNV
1 stop4h 59mDelta
Deal found 11/4$527
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:11 amGNV - OMA
1 stop5h 12mDelta
Mon 11/173:08 pmOMA - GNV
1 stop7h 03mDelta
Deal found 11/2$531
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/191:02 pmGNV - MLI
1 stop4h 54mAmerican Airlines
Sun 11/239:48 amMLI - GNV
2 stops8h 46mAmerican Airlines
Deal found 11/4$532
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:15 pmGNV - OMA
1 stop8h 15mAmerican Airlines
Mon 11/172:07 pmOMA - GNV
2 stops8h 52mAmerican Airlines
Deal found 11/2$540
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amGNV - OMA
2 stops9h 43mAmerican Airlines
Sun 11/165:00 amOMA - GNV
2 stops10h 21mAmerican Airlines
Deal found 11/2$579

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Gainesville

Fly to

Iowa

Route

Depart

Return

Price

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Sat 3/28

5:30 pm-12:01 am

1 stop7h 31m

Omaha Eppley Airfield

Tue 3/31

7:00 am-12:25 pm

1 stop4h 25m

$327

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 3/7

5:30 pm-10:32 pm

1 stop6h 02m

Moline Quad-City

Tue 3/10

5:55 am-12:25 pm

1 stop5h 30m

$427

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Wed 11/19

7:04 pm-12:14 am

1 stop6h 10m

Omaha Eppley Airfield

Sun 11/23

5:55 pm-11:11 pm

1 stop4h 16m

$455

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Wed 11/19

4:59 pm-10:32 pm

1 stop6h 33m

Omaha Eppley Airfield

Sun 11/23

6:00 am-4:21 pm

2 stops9h 21m

$464

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 3/7

4:25 pm-11:08 pm

1 stop7h 43m

Moline Quad-City

Tue 3/10

6:23 am-4:10 pm

2 stops8h 47m

$492

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Thu 11/27

8:00 am-1:42 pm

1 stop6h 42m

Des Moines

Mon 12/1

3:31 pm-11:05 pm

1 stop6h 34m

$496

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 3/31

7:05 pm-10:28 pm

1 stop4h 23m

Des Moines

Wed 4/1

5:15 pm-10:28 pm

1 stop4h 13m

$527

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Wed 11/19

7:04 pm-10:35 pm

1 stop4h 31m

Moline Quad-City

Sun 11/23

5:12 pm-11:11 pm

1 stop4h 59m

$527

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Sat 3/28

12:17 pm-10:33 pm

2 stops11h 16m

Omaha Eppley Airfield

Tue 3/31

1:53 pm-10:34 pm

1 stop7h 41m

$529

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Wed 11/19

1:02 pm-4:56 pm

1 stop4h 54m

Moline Quad-City

Sun 11/23

9:48 am-7:34 pm

2 stops8h 46m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 12 results
1
2

Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

What is the cheapest month to book a flight from Gainesville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in December is currently the most expensive (average of $174). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to IA?

Find hourly flight availability from Gainesville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

One of the essential ways to save on airfare from Gainesville to Iowa is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 55% on airfare.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 5, 2025.
Get a feel of what it's like to fly with American Airlines from Gainesville to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,042 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,042 reviews
American Airlines
7.2
Good
11,042 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    Delta and American Airlines can get you from Gainesville to Iowa in just under 6h 33m. Your travel time can differ by up to 58m. The distance between Gainesville and Iowa is about 1106 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Omaha Eppley Airfield, Gainesville Regional - Des Moines or Gainesville Regional - Moline Quad-City as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in December is currently the most expensive (average of $174). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Gainesville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Gainesville to Iowa

Discover the top airline that operate flights from Gainesville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$394Average$1,129FlexibilityNo cancel feeOn-time71%

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