HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$264+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$287
(Delta)

One-way from

$264
(American Airlines)
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
Search Deals
From Gainesville Regional to Iowa
Search Deals
One-way flight from Gainesville Regional to Iowa
Search Deals

Find flight deals from Gainesville to Iowa

Cheapest flights from Gainesville to Iowa
Explore the most affordable flight options available from Gainesville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:04 pmGNV - MLI
1 stop4h 31mDelta
Thu 11/276:05 amMLI - GNV
1 stop5h 47mDelta
Deal found 11/18$407
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:55 pmGNV - MLI
1 stop4h 35mDelta
Thu 1/15:50 amMLI - GNV
1 stop4h 30mDelta
Deal found 11/18$489
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amGNV - OMA
1 stop5h 11mDelta
Mon 12/87:00 amOMA - GNV
1 stop4h 58mDelta
Deal found 11/19$527
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amGNV - OMA
2 stops8h 33mAmerican Airlines
Mon 12/86:09 amOMA - GNV
1 stop5h 29mAmerican Airlines
Deal found 11/19$532

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Gainesville

Fly to

Iowa

Route

Depart

Return

Price

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 1/13

2:12 pm-7:10 pm

1 stop5h 58m

Omaha Eppley Airfield

Sat 1/17

12:15 pm-5:38 pm

1 stop4h 23m

$287

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Sat 3/28

5:30 pm-11:59 pm

1 stop7h 29m

Omaha Eppley Airfield

Tue 3/31

11:05 am-6:21 pm

1 stop6h 16m

$331

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 1/13

6:35 am-5:47 pm

2 stops12h 12m

Omaha Eppley Airfield

Sat 1/17

6:10 am-12:30 pm

1 stop5h 20m

$356

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 2/3

7:00 pm-10:29 pm

1 stop4h 29m

Des Moines

Sat 2/7

5:35 am-12:26 pm

1 stop5h 51m

$386

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 3/7

10:13 am-4:20 pm

1 stop7h 07m

Moline Quad-City

Tue 3/10

5:55 am-12:25 pm

1 stop5h 30m

$417

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Wed 1/21

4:59 pm-10:28 pm

1 stop6h 29m

Moline Quad-City

Sat 1/24

5:20 pm-10:29 pm

1 stop4h 09m

$417

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 2/3

5:00 pm-11:08 pm

1 stop7h 08m

Des Moines

Sat 2/7

6:00 am-4:26 pm

2 stops9h 26m

$422

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Fri 12/26

6:55 pm-10:30 pm

1 stop4h 35m

Moline Quad-City

Thu 1/1

5:50 am-11:20 am

1 stop4h 30m

$489

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 3/7

7:00 am-3:04 pm

1 stop9h 04m

Moline Quad-City

Tue 3/10

6:23 am-2:41 pm

2 stops7h 18m

$492

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Wed 1/21

6:00 am-3:27 pm

2 stops10h 27m

Moline Quad-City

Sat 1/24

6:15 am-12:30 pm

1 stop5h 15m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 16 results
1
2

Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

What is the cheapest month to book a flight from Gainesville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in January is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to IA?

Find hourly flight availability from Gainesville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

One of the essential ways to save on airfare from Gainesville to Iowa is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 55% on airfare.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with American Airlines from Gainesville to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,046 reviews

Crew

8.0

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,046 reviews
American Airlines
7.2
Good
11,046 reviews

Crew

8.0

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    Delta and American Airlines can get you from Gainesville to Iowa in just under 5h 58m. Your travel time can differ by up to 6h 14m. The distance between Gainesville and Iowa is about 1106 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Omaha Eppley Airfield, Gainesville Regional - Moline Quad-City or Gainesville Regional - Des Moines as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in January is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to John F Kennedy Intl flights
Miami to John F Kennedy Intl flights
Fort Lauderdale to John F Kennedy Intl flights
Fort Lauderdale to Newark flights
Fort Lauderdale to LaGuardia flights
Miami to LaGuardia flights
Miami to Newark flights
Tampa to John F Kennedy Intl flights
Tampa to LaGuardia flights
Tampa to Newark flights
Orlando to Newark flights
Orlando to LaGuardia flights
West Palm Beach to Newark flights
Orlando to Las Vegas flights
West Palm Beach to John F Kennedy Intl flights
Miami to Denver flights
Orlando to Dallas/Fort Worth flights
Orlando to Denver flights
Orlando to Los Angeles flights
Tampa to Las Vegas flights
Fort Lauderdale to Las Vegas flights
Fort Lauderdale to Dallas/Fort Worth flights
Jacksonville to John F Kennedy Intl flights
West Palm Beach to LaGuardia flights
Tampa to Denver flights
Fort Lauderdale to Atlanta flights
Miami to Los Angeles flights
Fort Lauderdale to Denver flights
Fort Lauderdale to Los Angeles flights
Tampa to Dulles Intl flights
Miami to Las Vegas flights
Fort Lauderdale to O'Hare Intl flights
Jacksonville to Newark flights
Tampa to Boston flights
Tampa to O'Hare Intl flights
Jacksonville to LaGuardia flights
Miami to Atlanta flights
Orlando to Hobby flights
Miami to Dallas/Fort Worth flights
Orlando to O'Hare Intl flights
Orlando to Reagan-National flights
Orlando to Seattle flights
Orlando to Dulles Intl flights
Orlando to Boston flights
Orlando to Sky Harbor Intl flights
Fort Lauderdale to Boston flights
Tampa to Dallas/Fort Worth flights
Fort Myers to Newark flights
Miami to Reagan-National flights
Miami to O'Hare Intl flights

Top airline flying from Gainesville to Iowa

Discover the top airline that operate flights from Gainesville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$394Average$1,129FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2025 Cheapflights