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$365+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Gainesville to Iowa

Best flights from Gainesville to Iowa
Discover carefully curated flight deals from Gainesville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/95:00 pmGNV - OMA
1 stop6h 14mAmerican Airlines
Sun 1/115:04 pmOMA - GNV
1 stop5h 26mAmerican Airlines
Deal found 12/30$667

Find flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$667
(American Airlines)

One-way from

$365
(American Airlines)
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
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From Gainesville Regional to Iowa
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One-way flight from Gainesville Regional to Iowa
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Gainesville

Fly to

Iowa

Route

Depart

Return

Price

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Fri 1/9

5:00 pm-10:14 pm

1 stop6h 14m

Omaha Eppley Airfield

Sun 1/11

5:04 pm-11:30 pm

1 stop5h 26m

$667

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Wed 1/7

6:58 pm-11:08 pm

1 stop5h 10m

$365

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 1/6

6:58 pm-11:08 pm

1 stop5h 10m

$365

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Mon 1/5

6:30 am-1:21 pm

1 stop7h 51m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

What is the cheapest month to book a flight from Gainesville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated December 30, 2025.
Get a feel of what it's like to fly with American Airlines from Gainesville to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,073 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,073 reviews
American Airlines
7.2
Good
11,073 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    American Airlines can get you from Gainesville to Iowa in just under 6h 14m. Your travel time can differ by up to . The distance between Gainesville and Iowa is about 1106 mi.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Des Moines, Gainesville Regional - Moline Quad-City or Gainesville Regional - Omaha Eppley Airfield as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $49). Flying from Gainesville to Iowa in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Gainesville to Iowa

Discover the top airline that operate flights from Gainesville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$394Average$1,129FlexibilityNo cancel feeOn-time71%

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