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$272+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
May 9 — May 161
Sat 5/9
Sat 5/16
1 adult, Economy
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Cheap flight deals from Gainesville to Iowa

Cheapest flights from Gainesville to Iowa
Explore the most affordable flight options available from Gainesville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.

This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 am
GNV
-
DSM
1 stop7h 47m
American Airlines
Wed 5/202:02 pm
DSM
-
GNV
1 stop7h 17m
American Airlines
Deal found 4/8$377
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:32 pm
GNV
-
DSM
1 stop5h 45m
American Airlines
Sat 5/301:48 pm
DSM
-
GNV
2 stops9h 45m
American Airlines
Deal found 4/8$431
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:47 pm
GNV
-
OMA
1 stop7h 35m
American Airlines
Wed 5/132:50 pm
OMA
-
GNV
1 stop6h 29m
American Airlines
Deal found 4/8$435
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:04 pm
GNV
-
MLI
1 stop4h 30m
Delta
Mon 6/155:17 pm
MLI
-
GNV
1 stop4h 33m
Delta
Deal found 4/6$435
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:48 am
GNV
-
MLI
2 stops9h 38m
American Airlines
Mon 6/154:24 pm
MLI
-
GNV
1 stop7h 09m
American Airlines
Deal found 4/6$440
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:03 pm
GNV
-
DSM
1 stop4h 31m
Delta
Sat 4/252:44 pm
DSM
-
GNV
1 stop6h 55m
Delta
Deal found 4/5$475
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
GNV
-
OMA
1 stop6h 26m
American Airlines
Sun 5/314:56 pm
OMA
-
GNV
1 stop5h 50m
American Airlines
Deal found 4/5$475
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:25 am
GNV
-
DSM
2 stops9h 22m
American Airlines
Sat 4/253:20 pm
DSM
-
GNV
1 stop6h 29m
American Airlines
Deal found 4/5$480
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:48 am
GNV
-
MLI
2 stops9h 32m
American Airlines
Mon 8/34:20 pm
MLI
-
GNV
1 stop6h 53m
American Airlines
Deal found 4/8$501
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:21 pm
GNV
-
OMA
1 stop7h 02m
American Airlines
Mon 7/135:03 pm
OMA
-
GNV
1 stop6h 10m
American Airlines
Deal found 4/7$512
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:32 pm
GNV
-
OMA
1 stop5h 50m
American Airlines
Sun 6/145:04 pm
OMA
-
GNV
1 stop6h 29m
American Airlines
Deal found 4/7$527
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:14 pm
GNV
-
OMA
1 stop7h 18m
American Airlines
Mon 4/276:25 am
OMA
-
GNV
1 stop7h 16m
American Airlines
Deal found 4/8$557

Find flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated April 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$377
(Delta)

One-way from

$272
(Delta)
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
Search Deals
From Gainesville Regional to Iowa
Search Deals
One-way flight from Gainesville Regional to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 5/26

7:05 pm-10:32 pm

1 stop4h 27m

Des Moines

Sat 5/30

5:27 am-12:22 pm

1 stop5h 55m

$377

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 5/12

6:25 am-1:48 pm

2 stops8h 23m

Des Moines

Wed 5/20

2:24 pm-11:59 pm

2 stops8h 35m

$387

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Tue 6/9

9:48 am-3:59 pm

1 stop7h 11m

Moline Quad-City

Mon 6/15

4:45 pm-11:46 pm

1 stop6h 01m

$435
Quickest round-trip

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Tue 6/9

7:04 pm-10:34 pm

1 stop4h 30m

Moline Quad-City

Mon 6/15

5:17 pm-10:50 pm

1 stop4h 33m

$435

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 8/1

7:00 am-10:22 am

1 stop4h 22m

Moline Quad-City

Mon 8/3

5:07 pm-10:48 pm

1 stop4h 41m

$435

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Wed 5/6

6:30 am-2:00 pm

1 stop8h 30m

Omaha Eppley Airfield

Wed 5/13

2:55 pm-11:59 pm

2 stops8h 04m

$440

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 4/21

7:03 pm-10:34 pm

1 stop4h 31m

Des Moines

Sat 4/25

2:44 pm-10:39 pm

1 stop6h 55m

$475

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Wed 5/27

6:00 am-11:26 am

1 stop6h 26m

Omaha Eppley Airfield

Sun 5/31

4:56 pm-11:46 pm

1 stop5h 50m

$475

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Tue 4/21

6:25 am-2:47 pm

2 stops9h 22m

Des Moines

Sat 4/25

3:20 pm-10:49 pm

1 stop6h 29m

$480

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 8/1

9:48 am-6:20 pm

2 stops9h 32m

Moline Quad-City

Mon 8/3

4:20 pm-12:13 am

1 stop6h 53m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/5

Showing 1-10 of 31 resultsSorted by cheapest first
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Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

What is the cheapest month to book a flight from Gainesville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $47). Flying from Gainesville to Iowa in February is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 9, 2026.
Get a feel of what it's like to fly with American Airlines from Gainesville to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,563 reviews

Entertainment

6.9

Overall

7.1

Boarding

7.5

Comfort

7.2

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,563 reviews
American Airlines
7.1
Good
11,563 reviews

Entertainment

6.9

Overall

7.1

Boarding

7.5

Comfort

7.2

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    Delta and American Airlines can get you from Gainesville to Iowa in just under 4h 27m. Your travel time can differ by up to 3h 56m. The distance between Gainesville and Iowa is about 1036 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Des Moines, Gainesville Regional - Moline Quad-City or Gainesville Regional - Omaha Eppley Airfield as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $47). Flying from Gainesville to Iowa in February is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Gainesville to Iowa

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Top airline flying from Gainesville to Iowa

Discover the top airline that operate flights from Gainesville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$394Average$1,129FlexibilityNo cancel feeOn-time71%

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