HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$348+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to Iowa

Cheapest flights from Gainesville to Iowa
Explore the most affordable flight options available from Gainesville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:15 pm
GNV
-
OMA
1 stop8h 16m
American Airlines
Sat 4/43:57 pm
OMA
-
GNV
1 stop6h 03m
American Airlines
Deal found 3/16$423
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:15 pm
GNV
-
DSM
1 stop8h 31m
American Airlines
Wed 4/11:52 pm
DSM
-
GNV
1 stop7h 35m
American Airlines
Deal found 3/13$475
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/43:09 pm
GNV
-
DSM
1 stop7h 50m
American Airlines
Mon 4/61:52 pm
DSM
-
GNV
1 stop7h 35m
American Airlines
Deal found 3/15$481
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 pm
GNV
-
DSM
1 stop4h 38m
Delta
Sat 4/115:35 am
DSM
-
GNV
1 stop6h 12m
Delta
Deal found 3/16$495
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:21 pm
GNV
-
OMA
1 stop7h 05m
American Airlines
Mon 6/294:56 pm
OMA
-
GNV
1 stop5h 50m
American Airlines
Deal found 3/13$495
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:59 pm
GNV
-
DSM
1 stop6h 39m
Delta
Wed 4/811:33 am
DSM
-
GNV
1 stop5h 42m
Delta
Deal found 3/16$541
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:34 pm
GNV
-
DSM
1 stop6h 04m
Delta
Thu 4/95:20 pm
DSM
-
GNV
1 stop4h 17m
Delta
Deal found 3/16$547
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:24 am
GNV
-
DSM
2 stops12h 55m
American Airlines
Sun 4/56:40 am
DSM
-
GNV
2 stops9h 38m
American Airlines
Deal found 3/15$564
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 pm
GNV
-
OMA
1 stop6h 11m
Delta
Mon 3/235:37 am
OMA
-
GNV
1 stop6h 10m
Delta
Deal found 3/16$595
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:32 pm
GNV
-
DSM
1 stop5h 38m
American Airlines
Sun 6/214:50 pm
DSM
-
GNV
1 stop5h 56m
American Airlines
Deal found 3/15$605
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:15 pm
GNV
-
MLI
1 stop7h 38m
American Airlines
Fri 4/312:40 pm
MLI
-
GNV
1 stop5h 40m
American Airlines
Deal found 3/12$612
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
GNV
-
OMA
1 stop6h 26m
American Airlines
Fri 5/294:56 pm
OMA
-
GNV
1 stop5h 50m
American Airlines
Deal found 3/13$695

Find flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$423
(American Airlines)

One-way from

$348
(American Airlines)
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
Search Deals
From Gainesville Regional to Iowa
Search Deals
One-way flight from Gainesville Regional to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 3/31

4:15 pm-11:31 pm

1 stop8h 16m

Omaha Eppley Airfield

Sat 4/4

3:57 pm-11:00 pm

1 stop6h 03m

$423

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 4/7

7:00 pm-12:11 am

1 stop6h 11m

Omaha Eppley Airfield

Sat 4/11

5:37 am-12:47 pm

1 stop6h 10m

$443

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Sat 4/4

6:00 am-11:05 am

1 stop6h 05m

Omaha Eppley Airfield

Wed 4/8

5:37 am-12:47 pm

1 stop6h 10m

$443

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Thu 8/20

7:01 am-11:22 am

1 stop5h 21m

Omaha Eppley Airfield

Sun 8/23

6:00 am-4:22 pm

2 stops9h 22m

$468

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 3/28

4:15 pm-11:46 pm

1 stop8h 31m

Des Moines

Wed 4/1

1:52 pm-10:27 pm

1 stop7h 35m

$475

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 4/4

5:45 pm-9:59 pm

1 stop5h 14m

Des Moines

Sun 4/5

7:00 am-2:43 pm

1 stop6h 43m

$481

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 4/4

7:17 am-2:56 pm

1 stop8h 39m

Des Moines

Mon 4/6

5:00 am-2:43 pm

2 stops8h 43m

$486

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Fri 6/26

5:21 pm-11:26 pm

1 stop7h 05m

Omaha Eppley Airfield

Mon 6/29

4:56 pm-11:46 pm

1 stop5h 50m

$495

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Fri 4/3

4:59 pm-10:38 pm

1 stop6h 39m

Des Moines

Wed 4/8

11:33 am-6:15 pm

1 stop5h 42m

$541

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sun 6/14

7:32 pm-12:10 am

1 stop5h 38m

Des Moines

Sun 6/21

4:50 pm-11:46 pm

1 stop5h 56m

$605

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

What is the cheapest month to book a flight from Gainesville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $48). Flying from Gainesville to Iowa in February is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 16, 2026.
Get a feel of what it's like to fly with American Airlines from Gainesville to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,467 reviews

Boarding

7.5

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,467 reviews
American Airlines
7.1
Good
11,467 reviews

Boarding

7.5

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    American Airlines and Delta can get you from Gainesville to Iowa in just under 6h 11m. Your travel time can differ by up to 2h 05m. The distance between Gainesville and Iowa is about 1106 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Des Moines, Gainesville Regional - Moline Quad-City or Gainesville Regional - Omaha Eppley Airfield as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Gainesville to Iowa (average of $48). Flying from Gainesville to Iowa in February is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Miami to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
Fort Lauderdale to Newark flights
Miami to LaGuardia flights
Miami to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
Orlando to Las Vegas flights
Orlando to Newark flights
Orlando to LaGuardia flights
Tampa to Newark flights
Tampa to LaGuardia flights
Orlando to Seattle flights
West Palm Beach to Newark flights
Tampa to John F Kennedy Intl flights
Orlando to Los Angeles flights
Tampa to Seattle flights
Fort Lauderdale to Las Vegas flights
West Palm Beach to John F Kennedy Intl flights
Orlando to Denver flights
Orlando to O'Hare Intl flights
Orlando to Dallas/Fort Worth flights
Tampa to Las Vegas flights
Tampa to Denver flights
Miami to Los Angeles flights
Miami to Las Vegas flights
Miami to Seattle flights
Orlando to Dulles Intl flights
Orlando to Baltimore flights
Tampa to Boston flights
West Palm Beach to LaGuardia flights
Fort Lauderdale to Los Angeles flights
Miami to Reagan-National flights
Orlando to Reagan-National flights
Orlando to Philadelphia flights
Tampa to O'Hare Intl flights
Fort Lauderdale to Atlanta flights
Orlando to Hobby flights
Miami to Denver flights
Fort Lauderdale to Denver flights
Fort Lauderdale to Seattle flights
Fort Lauderdale to Dallas/Fort Worth flights
Fort Lauderdale to Baltimore flights
Miami to San Francisco flights
Miami to Boston flights
Miami to Baltimore flights
Tampa to Dulles Intl flights
Fort Myers to Newark flights
Fort Lauderdale to Boston flights
Orlando to Boston flights

Top airline flying from Gainesville to Iowa

Discover the top airline that operate flights from Gainesville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$394Average$1,129FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights