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$295+ Cheap flights from South Padre Island, TX to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — IND
Jun 12 — Jun 191
Fri 6/12
Fri 6/19
1 adult, Economy
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Cheap flight deals from South Padre Island to Indianapolis

Cheapest flights from South Padre Island to Indianapolis
Explore the most affordable flight options available from South Padre Island to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.

This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:47 pm
BRO
-
IND
1 stop6h 41m
American Airlines
Mon 6/156:01 am
IND
-
BRO
1 stop5h 13m
American Airlines
Deal found 5/11$349
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:44 am
BRO
-
IND
1 stop7h 44m
American Airlines
Mon 6/18:21 pm
IND
-
BRO
1 stop5h 02m
American Airlines
Deal found 5/10$359
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:30 am
BRO
-
IND
1 stop6h 15m
American Airlines
Sat 5/305:22 pm
IND
-
BRO
1 stop8h 01m
American Airlines
Deal found 5/11$369
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:38 pm
BRO
-
IND
1 stop5h 52m
United Airlines
Sat 8/2211:48 am
IND
-
BRO
1 stop5h 03m
United Airlines
Deal found 5/12$409
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:44 am
BRO
-
IND
1 stop6h 21m
American Airlines
Thu 5/218:21 pm
IND
-
BRO
1 stop5h 02m
American Airlines
Deal found 5/12$529

Find flight deals from South Padre Island to Indianapolis

Keep the following information in mind while searching for South Padre Island to Indianapolis flight deals. Data was last updated May 13, 2026.

Round-trip from

$349
(American Airlines)

One-way from

$295
(American Airlines)
From South Padre Island to Indianapolis
Search Deals
One-way flight from South Padre Island to Indianapolis
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Padre Island to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from South Padre Island to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Tue 8/18

4:38 pm-11:30 pm

1 stop5h 52m

Indianapolis

Sat 8/22

11:48 am-3:51 pm

1 stop5h 03m

$409

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Tue 6/9

6:42 pm-9:13 am

2 stops13h 31m

Indianapolis

Mon 6/15

8:17 pm-12:23 am

1 stop5h 06m

$421
Cheapest one-way
Quickest one-way

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Wed 5/20

10:44 am-6:05 pm

1 stop6h 21m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Sorted by cheapest first

Best time to book a flight from South Padre Island to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Padre Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Padre Island to Indianapolis
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Padre Island to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Padre Island?

    Most people fly into Indianapolis (IND) if they book a flight to Indianapolis from South Padre Island. On average, Indianapolis has 0 inbound flights from South Padre Island per day from 4 airlines. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from South Padre Island to Indianapolis?

    For as low as $409, United Airlines can have you in Indianapolis from South Padre Island in 5h 52m. There are 1149 mi between South Padre Island and Indianapolis. This flight may include one or multiple stops.

  • Can I find deals for flights from South Padre Island to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Padre Island to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Padre Island to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Padre Island to Indianapolis.

  • Can I find deals for business class flights from South Padre Island to Indianapolis?

    Yes. Cheapflights offers flight deals from South Padre Island to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
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Noblesville
Bloomington

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Alternative routes for South Padre Island to Indianapolis

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Top 4 airlines flying from South Padre Island to Indianapolis

Discover the top 4 airlines that operate flights from South Padre Island to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$310FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$224Average$424FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$229Average$302FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$258Average$395FlexibilityNo cancel feeOn-time69%

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