$170+ Cheap flights from Roanoke to Indianapolis (ROA - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Roanoke to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Roanoke to IndianapolisExplore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:01 pm -
1 stop4h 45m
Fri 11/275:45 am -
1 stop4h 06m
Deal found 11/2![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:03 pm -
1 stop5h 54m
Sun 12/137:49 am -
1 stop5h 55m
Deal found 11/4![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop4h 43m
Sat 11/215:22 pm -
1 stop4h 33m
Deal found 11/2![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:50 pm -
2 stops18h 56m
Sun 12/1311:00 am -
1 stop9h 00m
Deal found 11/2![Multiple Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:01 pm -
1 stop4h 45m
Sun 11/85:45 am -
1 stop4h 06m
Deal found 11/1![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:54 pm -
1 stop4h 24m
Sun 12/66:00 am -
1 stop4h 37m
Deal found 11/2![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:58 pm -
1 stop6h 06m
Sun 12/67:49 am -
1 stop4h 53m
Deal found 11/2![American Airlines logo]()
$433
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:52 am -
1 stop7h 56m
Fri 11/202:56 pm -
1 stop20h 00m
Deal found 10/31![Allegiant Air logo]()
$437
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:25 am -
1 stop6h 01m
Sat 12/1212:54 pm -
3 stops25h 16m
Deal found 11/4![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 pm -
2 stops13h 09m
Sun 12/65:00 am -
1 stop4h 27m
Deal found 11/2![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:35 am -
2 stops17h 45m
Sun 12/137:15 am -
1 stop6h 08m
Deal found 11/4![United Airlines logo]()
$602
Best flights from Roanoke to IndianapolisDiscover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:05 pm -
1 stop4h 29m
Sat 12/129:00 am -
1 stop4h 29m
Deal found 11/4![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop4h 43m
Sat 11/215:22 pm -
1 stop4h 33m
Deal found 11/2![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:50 pm -
2 stops18h 56m
Sun 12/1311:00 am -
1 stop9h 00m
Deal found 11/2![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:52 am -
1 stop7h 56m
Fri 11/202:56 pm -
1 stop20h 00m
Deal found 10/31![Allegiant Air logo]()
$437
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:01 pm -
1 stop4h 45m
Fri 11/275:45 am -
1 stop4h 06m
Deal found 10/31![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/69:04 am -
1 stop6h 08m
Sun 1/104:43 pm -
1 stop5h 01m
Deal found 11/4![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:54 pm -
1 stop4h 24m
Sun 12/66:00 am -
1 stop4h 37m
Deal found 11/2![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/23:05 pm -
1 stop4h 24m
Sat 2/68:00 pm -
1 stop4h 45m
Deal found 11/1![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:05 pm -
1 stop6h 41m
Wed 1/276:37 pm -
1 stop6h 08m
Deal found 10/31![United Airlines logo]()
$409
Last-minute flights from Roanoke to IndianapolisDiscover last-minute flight deals from Roanoke to Indianapolis. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Indianapolis. Data last updated November 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:01 pm -
1 stop4h 45m
Sun 11/85:45 am -
1 stop4h 06m
Deal found 11/1![United Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:52 am -
1 stop7h 56m
Fri 11/202:56 pm -
1 stop20h 00m
Deal found 10/31![Allegiant Air logo]()
$437
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop4h 43m
Sat 11/215:22 pm -
1 stop4h 33m
Deal found 11/2![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:01 pm -
1 stop4h 45m
Fri 11/275:45 am -
1 stop4h 06m
Deal found 11/2![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:54 pm -
1 stop4h 24m
Sun 12/66:00 am -
1 stop4h 37m
Deal found 11/2![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:58 pm -
1 stop6h 06m
Sun 12/67:49 am -
1 stop4h 53m
Deal found 11/2![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 pm -
2 stops13h 09m
Sun 12/65:00 am -
1 stop4h 27m
Deal found 11/2![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:25 am -
1 stop6h 01m
Sat 12/1212:54 pm -
3 stops25h 16m
Deal found 11/4![United Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:03 pm -
1 stop5h 54m
Sun 12/137:49 am -
1 stop5h 55m
Deal found 11/4![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:35 am -
2 stops17h 45m
Sun 12/137:15 am -
1 stop6h 08m
Deal found 11/4![United Airlines logo]()
$602
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:50 pm -
2 stops18h 56m
Sun 12/1311:00 am -
1 stop9h 00m
Deal found 11/2![Multiple Airlines logo]()
$377
One-way flights from Roanoke to IndianapolisSearch for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:51 pm -
1 stop6h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Allegiant Air logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:51 pm -
2 stops23h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:04 pm -
1 stop4h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/293:57 pm -
1 stop22h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/293:57 pm -
3 stops44h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:00 pm -
2 stops13h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$623
Find flight deals from Roanoke to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (United Airlines) |
One-way from | $170 (Kiwi.com) |
Popular in | May |
Cheapest in | March |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Roanoke to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Fri 12/11
3:51 pm-10:25 pm
1 stop6h 34m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Fri 12/11
3:51 pm-3:46 pm
2 stops23h 55m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
Quickest round-trip
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Sat 12/12
2:04 pm-6:30 pm
1 stop4h 26m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Sat 12/5
3:05 pm-7:34 pm
1 stop4h 29m
Indianapolis
Sat 12/12
9:00 am-1:29 pm
1 stop4h 29m
$319
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Wed 11/25
2:01 pm-6:46 pm
1 stop4h 45m
Indianapolis
Fri 11/27
5:45 am-9:51 am
1 stop4h 06m
$319
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Wed 1/6
9:04 am-3:12 pm
1 stop6h 08m
Indianapolis
Sun 1/10
4:43 pm-9:44 pm
1 stop5h 01m
$319
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Tue 11/17
6:00 am-10:43 am
1 stop4h 43m
Indianapolis
Sat 11/21
5:22 pm-9:55 pm
1 stop4h 33m
$349
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Thu 12/10
8:50 pm-3:46 pm
2 stops18h 56m
Indianapolis
Sun 12/13
11:00 am-8:00 pm
1 stop9h 00m
$377
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Mon 11/30
6:54 pm-11:18 pm
1 stop4h 24m
Indianapolis
Sun 12/6
6:00 am-10:37 am
1 stop4h 37m
$409
RoanokeIndianapolis
ROA Roanoke - IND Indianapolis
ROAIND
Roanoke
Tue 2/2
3:05 pm-7:29 pm
1 stop4h 24m
Indianapolis
Sat 2/6
8:00 pm-12:45 am
1 stop4h 45m
$409
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Indianapolis in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Roanoke with our price prediction graph.
ROA-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Indianapolis
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated November 5, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Roanoke to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsPlainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Speedway
Noblesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Indianapolis flight routes
Other flight options
Other flights from Roanoke
Popular flights
Alternative routes for Roanoke to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Roanoke to Indianapolis by cabin class
Find flights from Roanoke to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Roanoke and Indianapolis flights
Browse other Roanoke and Indianapolis flight options. Last updated on November 5, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Roanoke to Indianapolis
Discover the top 3 airlines that operate flights from Roanoke to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$249 | Average$464 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$254 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$274 | Average$396 | FlexibilityNo cancel fee | On-time71% |