$133+ Cheap flights from Roanoke to Indianapolis (ROA - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Aug 10 — Aug 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to IndianapolisExplore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
Explore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
ROA
- IND
1 stop5h 37m
American Airlines
Mon 8/37:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/9![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 am
ROA
- IND
1 stop3h 47m
American Airlines
Mon 7/277:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/8![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:50 pm
ROA
- IND
1 stop5h 50m
United Airlines
Wed 9/1612:40 pm
IND
- ROA
1 stop4h 29m
United Airlines
Deal found 7/7![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:00 am
ROA
- IND
1 stop3h 50m
American Airlines
Sun 8/27:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/9![American Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- IND
1 stop5h 40m
American Airlines
Sun 8/26:42 am
IND
- ROA
1 stop3h 58m
American Airlines
Deal found 7/9![American Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:29 pm
ROA
- IND
1 stop6h 18m
American Airlines
Tue 7/145:25 pm
IND
- ROA
1 stop6h 34m
American Airlines
Deal found 7/9![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:53 pm
ROA
- IND
1 stop4h 16m
American Airlines
Sun 7/267:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/11![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:52 pm
ROA
- IND
1 stop5h 52m
United Airlines
Sun 7/265:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 7/7![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:38 pm
ROA
- IND
1 stop6h 03m
United Airlines
Sat 12/126:00 am
IND
- ROA
1 stop4h 11m
United Airlines
Deal found 7/10![United Airlines logo]()
$438
Best flights from Roanoke to IndianapolisDiscover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
Discover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 pm
ROA
- IND
1 stop4h 42m
Delta
Mon 9/286:40 pm
IND
- ROA
1 stop5h 19m
Delta
Deal found 7/9![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:38 pm
ROA
- IND
1 stop6h 03m
United Airlines
Sat 12/126:00 am
IND
- ROA
1 stop4h 11m
United Airlines
Deal found 7/10![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:15 am
ROA
- IND
2 stops10h 18m
United Airlines
Wed 9/1612:40 pm
IND
- ROA
1 stop4h 29m
United Airlines
Deal found 7/7![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:49 am
ROA
- IND
1 stop5h 53m
United Airlines
Mon 9/281:38 pm
IND
- ROA
2 stops10h 06m
United Airlines
Deal found 7/11![United Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:52 pm
ROA
- IND
1 stop4h 13m
United Airlines
Mon 7/278:10 pm
IND
- ROA
2 stops13h 32m
United Airlines
Deal found 7/6![United Airlines logo]()
$508
Last-minute flights from Roanoke to IndianapolisDiscover last-minute flight deals from Roanoke to Indianapolis. Data last updated July 11, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Indianapolis. Data last updated July 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:29 pm
ROA
- IND
1 stop6h 18m
American Airlines
Tue 7/145:25 pm
IND
- ROA
1 stop6h 34m
American Airlines
Deal found 7/9![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 am
ROA
- IND
1 stop3h 47m
American Airlines
Mon 7/277:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/8![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:52 pm
ROA
- IND
1 stop5h 52m
United Airlines
Sun 7/265:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 7/7![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:53 pm
ROA
- IND
1 stop4h 16m
American Airlines
Sun 7/267:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/11![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- IND
1 stop5h 40m
American Airlines
Sun 8/26:42 am
IND
- ROA
1 stop3h 58m
American Airlines
Deal found 7/9![American Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
ROA
- IND
1 stop5h 37m
American Airlines
Mon 8/37:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/9![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:00 am
ROA
- IND
1 stop3h 50m
American Airlines
Sun 8/27:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 7/9![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:40 am
ROA
- IND
1 stop6h 14m
United Airlines
Wed 8/1212:34 pm
IND
- ROA
2 stops11h 09m
United Airlines
Deal found 7/8![United Airlines logo]()
$482
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:30 am
ROA
- IND
2 stops11h 35m
United Airlines
Fri 8/145:45 am
IND
- ROA
1 stop4h 02m
United Airlines
Deal found 7/9![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:15 am
ROA
- IND
2 stops11h 39m
United Airlines
Sun 8/235:45 am
IND
- ROA
1 stop4h 03m
United Airlines
Deal found 7/9![United Airlines logo]()
$487
One-way flights from Roanoke to IndianapolisSearch for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
Search for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:27 pm
ROA
- IND
1 stop27h 11m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$133
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:05 am
ROA
- IND
1 stop3h 43m
American Airlines
Deal found 7/10![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:40 am
ROA
- IND
1 stop6h 14m
United Airlines
Deal found 7/8![United Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/262:56 pm
ROA
- IND
2 stops19h 16m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:00 am
ROA
- IND
1 stop3h 50m
American Airlines
Deal found 7/10![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:15 am
ROA
- IND
2 stops8h 48m
United Airlines
Deal found 7/9![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:15 am
ROA
- IND
2 stops12h 46m
United Airlines
Deal found 7/10![United Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:15 am
ROA
- IND
2 stops26h 08m
United Airlines
Deal found 7/10![United Airlines logo]()
$525
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
ROA
- IND
3 stops30h 50m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$649
Find flight deals from Roanoke to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (American Airlines) |
One-way from | $133 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $323 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Roanoke to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Fri 9/25
6:40 pm-11:22 pm
1 stop4h 42m
Indianapolis
Mon 9/28
6:40 pm-11:59 pm
1 stop5h 19m
$289
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Wed 12/9
5:38 pm-11:41 pm
1 stop6h 03m
Indianapolis
Sat 12/12
6:00 am-10:11 am
1 stop4h 11m
$438
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sat 9/12
6:15 am-4:33 pm
2 stops10h 18m
Indianapolis
Wed 9/16
12:40 pm-5:09 pm
1 stop4h 29m
$454
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Fri 9/25
6:49 am-12:42 pm
1 stop5h 53m
Indianapolis
Mon 9/28
1:38 pm-11:44 pm
2 stops10h 06m
$467
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sat 7/25
5:52 pm-10:05 pm
1 stop4h 13m
Indianapolis
Mon 7/27
8:10 pm-9:42 am
2 stops13h 32m
$508
Cheapest one-way
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Mon 8/17
3:27 pm-6:38 pm
1 stop27h 11m
$133
Quickest one-way
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Tue 8/4
11:05 am-2:48 pm
1 stop3h 43m
$259
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sun 7/26
6:40 am-12:54 pm
1 stop6h 14m
$318
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Tue 7/28
10:47 am-3:03 pm
1 stop4h 16m
$318
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Fri 7/17
5:00 am-8:50 am
1 stop3h 50m
$369
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Indianapolis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Roanoke with our price prediction graph.
ROA-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Indianapolis
What is the cheapest month to book a flight from Roanoke to Indianapolis?
Currently, February is the cheapest month in which you can book a flight from Roanoke to Indianapolis (average of $288). Flying from Roanoke to Indianapolis in May is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Indianapolis?
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated July 11, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Roanoke to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
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Roanoke and Indianapolis flights
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Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on July 11, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Roanoke to Indianapolis
Discover the top 3 airlines that operate flights from Roanoke to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$297 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$288 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$249 | Average$387 | FlexibilityNo cancel fee | On-time69% |