$259+ Cheap flights from Roanoke to Indianapolis (ROA - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Jun 14 — Jun 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Roanoke to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Roanoke to IndianapolisExplore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
Explore the most affordable flight options available from Roanoke to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:57 pm
ROA
- IND
1 stop4h 44m
Delta
Mon 7/276:37 pm
IND
- ROA
1 stop5h 48m
Delta
Deal found 5/13![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:59 pm
ROA
- IND
1 stop4h 36m
Delta
Wed 6/175:55 pm
IND
- ROA
1 stop5h 26m
Delta
Deal found 5/11![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:53 pm
ROA
- IND
1 stop4h 17m
American Airlines
Wed 8/127:27 am
IND
- ROA
1 stop7h 03m
American Airlines
Deal found 5/13![American Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:30 pm
ROA
- IND
1 stop3h 56m
Delta
Sat 6/66:00 am
IND
- ROA
1 stop4h 30m
Delta
Deal found 5/11![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
ROA
- IND
1 stop5h 31m
American Airlines
Wed 6/38:05 am
IND
- ROA
1 stop6h 39m
American Airlines
Deal found 5/15![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:00 am
ROA
- IND
1 stop3h 50m
American Airlines
Sun 8/27:00 am
IND
- ROA
1 stop7h 24m
American Airlines
Deal found 5/13![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:58 pm
ROA
- IND
1 stop4h 09m
American Airlines
Wed 5/2711:29 am
IND
- ROA
1 stop4h 43m
American Airlines
Deal found 5/13![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:35 am
ROA
- IND
1 stop7h 17m
United Airlines
Sun 6/145:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 5/11![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:02 pm
ROA
- IND
1 stop4h 42m
American Airlines
Sun 6/146:11 am
IND
- ROA
1 stop4h 34m
American Airlines
Deal found 5/14![American Airlines logo]()
$360
Best flights from Roanoke to IndianapolisDiscover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
Discover carefully curated flight deals from Roanoke to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:50 pm
ROA
- IND
1 stop4h 44m
Delta
Mon 9/286:25 pm
IND
- ROA
1 stop5h 25m
Delta
Deal found 5/15![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:02 pm
ROA
- IND
1 stop4h 42m
American Airlines
Sun 6/146:11 am
IND
- ROA
1 stop4h 34m
American Airlines
Deal found 5/14![American Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:15 am
ROA
- IND
2 stops12h 46m
United Airlines
Sat 6/135:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 5/12![United Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:12 am
ROA
- IND
1 stop6h 21m
Delta
Mon 7/2710:07 am
IND
- ROA
1 stop4h 40m
Delta
Deal found 5/14![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:30 pm
ROA
- IND
1 stop5h 03m
Delta
Tue 6/95:55 pm
IND
- ROA
1 stop5h 26m
Delta
Deal found 5/11![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
ROA
- IND
1 stop5h 40m
American Airlines
Sun 6/217:39 pm
IND
- ROA
1 stop4h 20m
American Airlines
Deal found 5/12![American Airlines logo]()
$402
Last-minute flights from Roanoke to IndianapolisDiscover last-minute flight deals from Roanoke to Indianapolis. Data last updated May 15, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Indianapolis. Data last updated May 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 pm
ROA
- IND
1 stop5h 03m
Delta
Sat 5/164:58 pm
IND
- ROA
1 stop6h 00m
Delta
Deal found 5/13![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:58 pm
ROA
- IND
1 stop4h 09m
American Airlines
Wed 5/2711:29 am
IND
- ROA
1 stop4h 43m
American Airlines
Deal found 5/13![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
ROA
- IND
1 stop5h 31m
American Airlines
Wed 6/38:05 am
IND
- ROA
1 stop6h 39m
American Airlines
Deal found 5/15![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:30 pm
ROA
- IND
1 stop3h 56m
Delta
Sat 6/66:00 am
IND
- ROA
1 stop4h 30m
Delta
Deal found 5/11![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:15 am
ROA
- IND
1 stop3h 58m
United Airlines
Sun 6/75:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 5/11![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
ROA
- IND
1 stop5h 40m
American Airlines
Sat 6/139:47 am
IND
- ROA
1 stop6h 17m
American Airlines
Deal found 5/13![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:35 am
ROA
- IND
1 stop7h 17m
United Airlines
Sun 6/145:35 am
IND
- ROA
1 stop4h 07m
United Airlines
Deal found 5/11![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:02 pm
ROA
- IND
1 stop4h 42m
American Airlines
Sun 6/146:11 am
IND
- ROA
1 stop4h 34m
American Airlines
Deal found 5/14![American Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:59 pm
ROA
- IND
1 stop4h 36m
Delta
Wed 6/175:55 pm
IND
- ROA
1 stop5h 26m
Delta
Deal found 5/11![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:42 pm
ROA
- IND
1 stop6h 02m
American Airlines
Sun 6/217:39 pm
IND
- ROA
1 stop4h 20m
American Airlines
Deal found 5/11![American Airlines logo]()
$401
One-way flights from Roanoke to IndianapolisSearch for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
Search for one-way flight options from Roanoke to Indianapolis. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
ROA
- IND
1 stop5h 40m
American Airlines
Deal found 5/13![American Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
ROA
- IND
1 stop9h 26m
American Airlines
Deal found 5/11![American Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:53 pm
ROA
- IND
1 stop4h 18m
American Airlines
Deal found 5/11![American Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:30 am
ROA
- IND
2 stops13h 14m
United Airlines
Deal found 5/11![United Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:15 am
ROA
- IND
2 stops10h 15m
United Airlines
Deal found 5/13![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:30 am
ROA
- IND
2 stops13h 14m
United Airlines
Deal found 5/11![United Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:15 am
ROA
- IND
2 stops17h 25m
United Airlines
Deal found 5/12![United Airlines logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:16 am
ROA
- IND
3 stops53h 00m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$895
Find flight deals from Roanoke to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (Delta) |
One-way from | $259 (Delta) |
Popular in | January |
Cheapest in | August |
Average price | $391 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Roanoke to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Fri 9/25
7:50 pm-12:34 am
1 stop4h 44m
Indianapolis
Mon 9/28
6:25 pm-11:50 pm
1 stop5h 25m
$289
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Wed 7/22
11:12 am-5:33 pm
1 stop6h 21m
Indianapolis
Mon 7/27
10:07 am-2:47 pm
1 stop4h 40m
$289
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Fri 6/5
7:30 pm-12:33 am
1 stop5h 03m
Indianapolis
Tue 6/9
5:55 pm-11:21 pm
1 stop5h 26m
$299
Quickest round-trip
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Tue 6/9
6:02 pm-10:44 pm
1 stop4h 42m
Indianapolis
Sun 6/14
6:11 am-10:45 am
1 stop4h 34m
$360
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Thu 6/18
6:00 am-11:40 am
1 stop5h 40m
Indianapolis
Sun 6/21
7:39 pm-11:59 pm
1 stop4h 20m
$402
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Tue 6/9
6:15 am-7:01 pm
2 stops12h 46m
Indianapolis
Sat 6/13
5:35 am-9:42 am
1 stop4h 07m
$481
Cheapest one-way
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Mon 8/31
11:20 am-5:03 pm
1 stop5h 43m
$259
Quickest one-way
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sat 6/6
6:00 am-11:40 am
1 stop5h 40m
$259
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sat 6/6
6:15 am-4:30 pm
2 stops10h 15m
$417
RoanokeIndianapolis
ROA - IND
ROAIND
Roanoke
Sat 7/11
10:30 am-11:44 pm
2 stops13h 14m
$418
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Indianapolis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Roanoke with our price prediction graph.
ROA-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Indianapolis
What is the cheapest month to book a flight from Roanoke to Indianapolis?
Currently, August is the cheapest month in which you can book a flight from Roanoke to Indianapolis (average of $263). Flying from Roanoke to Indianapolis in January is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Indianapolis?
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated May 15, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Roanoke to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Indianapolis flight routes
Other flight options
Other flights from Roanoke
Popular flights
Alternative routes for Roanoke to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Roanoke to Indianapolis by cabin class
Find flights from Roanoke to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 15, 2026.
Roanoke and Indianapolis flights
Browse other Roanoke and Indianapolis flight options. Last updated on May 15, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on May 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Roanoke to Indianapolis
Discover the top 3 airlines that operate flights from Roanoke to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$288 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$283 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$238 | Average$368 | FlexibilityNo cancel fee | On-time69% |