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$262+ Cheap flights from Panama City (PTY) to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$505
(United Airlines)

One-way from

$262
(Mytrip)

Popular in

August

Cheapest in

December

Average price

$637
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
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From Panama City Tocumen Intl to Indianapolis
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One-way flight from Panama City Tocumen Intl to Indianapolis
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Highest demand for flights based on searches. 11% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/94:41 pmPTY - IND
2 stops18h 42mUnited Airlines
Wed 1/217:15 amIND - PTY
2 stops12h 23mUnited Airlines
Deal found 10/18$505
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:55 amPTY - IND
1 stop14h 14mUnited Airlines
Wed 1/149:00 amIND - PTY
1 stop10h 38mUnited Airlines
Deal found 10/19$514
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:43 pmPTY - IND
2 stops20h 30mAmerican Airlines
Wed 1/145:07 pmIND - PTY
2 stops20h 20mAmerican Airlines
Deal found 10/19$518
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:55 amPTY - IND
1 stop11h 09mUnited Airlines
Wed 12/106:00 amIND - PTY
2 stops13h 38mUnited Airlines
Deal found 10/19$526
This Mytrip deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:25 amPTY - IND
2 stops13h 26mMultiple Airlines
Mon 12/812:38 pmIND - PTY
2 stops21h 52mMultiple Airlines
Deal found 10/18$558
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:55 pmPTY - IND
2 stops17h 08mUnited Airlines
Fri 1/96:34 pmIND - PTY
1 stop10h 36mUnited Airlines
Deal found 10/18$567
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:00 amPTY - IND
1 stop10h 11mUnited Airlines
Mon 12/87:00 amIND - PTY
1 stop12h 38mUnited Airlines
Deal found 10/18$569
This Mytrip deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:50 pmPTY - IND
2 stops19h 43mMultiple Airlines
Wed 1/216:35 amIND - PTY
3 stops18h 05mMultiple Airlines
Deal found 10/18$601

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Panama City

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/9

4:41 pm-11:23 am

2 stops18h 42m

Indianapolis

Wed 1/21

7:15 am-7:38 pm

2 stops12h 23m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/9

3:46 pm-12:26 am

1 stop8h 40m

Indianapolis

Wed 1/21

7:10 am-2:02 pm

1 stop6h 52m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 12/10

10:00 am-8:27 pm

1 stop10h 27m

Indianapolis

Wed 1/14

9:00 am-5:07 pm

1 stop8h 07m

$514

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/30

4:55 pm-1:18 pm

2 stops20h 23m

Indianapolis

Fri 1/9

5:30 am-3:38 pm

2 stops10h 08m

$518

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 12/10

2:50 pm-10:35 am

2 stops19h 45m

Indianapolis

Wed 1/14

4:45 pm-1:27 pm

2 stops20h 42m

$518

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/9

4:43 pm-12:07 pm

2 stops19h 24m

Indianapolis

Wed 1/21

6:00 am-1:27 pm

1 stop7h 27m

$518

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 11/6

11:25 am-11:29 pm

2 stops12h 04m

$262

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 11/6

3:21 pm-12:22 am

1 stop9h 01m

$328

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 11/12

3:37 pm-12:26 am

1 stop8h 49m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/19

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama City to Indianapolis (average of $254). Flying from Panama City to Indianapolis in January is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Indianapolis at noon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated October 20, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Panama City to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,978 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
Delta
7.9
Good
7,978 reviews
Delta
7.9
Good
7,978 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
United Airlines
7.4
Good
8,991 reviews
Delta
7.9
Good
7,978 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
American Airlines
7.2
Good
11,024 reviews
Delta
7.9
Good
7,978 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Indianapolis?

    There are many flights that can get you from Panama City to Indianapolis in 8h 40m. Fly via United Airlines or Delta to get the fastest option. The distance between Panama City and Indianapolis is about 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Panama City to Indianapolis round-trip?

    Currently priced at $312, Delta will fly you from Panama City to Indianapolis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $481 and $496, respectively. Delta is currently priced 49% below the average price you’ll pay for this route.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Indianapolis (average of $254). Flying from Panama City to Indianapolis in January is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to O'Hare Intl flights
Panama City to Louisville flights
Panama City to Cincinnati flights

Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$312Average$584FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$496Average$586FlexibilityNo cancel feeOn-time71%

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