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$307+ Cheap flights from Panama City (PTY) to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$524
(American Airlines)

One-way from

$307
(Delta)

Popular in

August

Cheapest in

December

Average price

$718
From Panama City Tocumen Intl to Indianapolis
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One-way flight from Panama City Tocumen Intl to Indianapolis
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Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:56 pmPTY - IND
2 stops20h 35mAmerican Airlines
Fri 1/98:25 amIND - PTY
1 stop7h 10mAmerican Airlines
Deal found 9/15$524
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:41 pmPTY - IND
1 stop18h 09mUnited Airlines
Fri 1/911:40 amIND - PTY
1 stop7h 58mUnited Airlines
Deal found 9/16$535
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:55 amPTY - IND
1 stop14h 49mUnited Airlines
Fri 11/149:00 amIND - PTY
1 stop10h 38mUnited Airlines
Deal found 9/15$556
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:15 pmPTY - IND
1 stop8h 20mAmerican Airlines
Sun 11/94:43 pmIND - PTY
2 stops21h 06mAmerican Airlines
Deal found 9/13$566
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:00 amPTY - IND
1 stop12h 30mUnited Airlines
Thu 11/66:45 amIND - PTY
1 stop12h 53mUnited Airlines
Deal found 9/15$571
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:34 pmPTY - IND
3 stops48h 09mMultiple Airlines
Thu 11/66:35 amIND - PTY
1 stop13h 44mMultiple Airlines
Deal found 9/15$581
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:15 pmPTY - IND
1 stop8h 20mAmerican Airlines
Mon 10/136:56 pmIND - PTY
2 stops20h 07mAmerican Airlines
Deal found 9/14$582

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Panama City

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/30

4:56 pm-1:31 pm

2 stops20h 35m

Indianapolis

Fri 1/9

8:25 am-3:35 pm

1 stop7h 10m

$524

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/30

4:41 pm-10:50 am

1 stop18h 09m

Indianapolis

Fri 1/9

11:40 am-7:38 pm

1 stop7h 58m

$535

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 10/28

3:41 pm-10:53 am

1 stop18h 12m

Indianapolis

Fri 11/14

6:45 am-2:45 pm

1 stop8h 00m

$556

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 10/28

3:15 pm-1:34 pm

2 stops21h 19m

Indianapolis

Fri 11/14

4:01 pm-1:49 pm

2 stops21h 48m

$561

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 11/12

3:37 pm-12:26 am

1 stop8h 49m

$307

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 11/12

4:41 pm-1:12 pm

2 stops20h 31m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Panama City to Indianapolis (average of $286). Flying from Panama City to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Indianapolis at noon. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Panama City to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Indianapolis?

    There are many flights that can get you from Panama City to Indianapolis in 18h 09m. Fly via American Airlines or United Airlines to get the fastest option. The distance between Panama City and Indianapolis is about 2158 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Panama City to Indianapolis round-trip?

    Currently priced at $312, Delta will fly you from Panama City to Indianapolis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $481 and $496, respectively. Delta is currently priced 49% below the average price you’ll pay for this route.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Indianapolis (average of $286). Flying from Panama City to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to O'Hare Intl flights
Panama City to Cincinnati flights
Panama City to Louisville flights

Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$312Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$496Average$644FlexibilityNo cancel feeOn-time71%

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