How long is the flight from Missouri to Illinois?

Departing from Missouri to Illinois will take you 1h 10m. The distance between Missouri and Illinois is about 251 mi. Most flights are nonstop.

In terms of precipitation, rainfall in Illinois ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Illinois when rainfall is around 1.7 in.

If weather is an important factor for your trip to Illinois, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Can I find deals for flights from Missouri to Illinois that include hotel bookings?

Yes. In addition to deals on Missouri to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Illinois?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Illinois.

Can I find deals for business class flights from Missouri to Illinois?

Yes. Cheapflights offers flight deals from Missouri to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$64+ Flights from Missouri to Illinois

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from Missouri to Illinois

Cheapest flights from Missouri to Illinois
Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/316:34 pmCOU - ORD

Nonstop1h 36mUnited Airlines

Sat 1/31:00 pmORD - COU

Nonstop1h 35mUnited Airlines

Deal found 12/16

$209

Wed 12/316:35 pmSTL - ORD

Nonstop1h 44mUnited Airlines

Thu 1/19:10 pmORD - STL

Nonstop1h 33mUnited Airlines

Deal found 12/17

$215

Wed 12/313:14 pmSGF - ORD

Nonstop1h 51mUnited Airlines

Sun 1/48:48 amORD - SGF

Nonstop2h 01mUnited Airlines

Deal found 12/16

$219

Wed 12/245:43 amMCI - ORD

2 stops11h 39mDelta

Wed 1/71:55 pmORD - MCI

2 stops9h 32mDelta

Deal found 12/16

$225

Wed 12/2410:27 amSGF - ORD

Nonstop1h 42mAmerican Airlines

Wed 12/313:46 pmORD - SGF

Nonstop1h 42mAmerican Airlines

Deal found 12/16

$227

Thu 12/257:08 amSGF - ORD

1 stop5h 32mAmerican Airlines

Thu 1/11:27 pmORD - SGF

Nonstop1h 45mAmerican Airlines

Deal found 12/16

$237

Tue 12/3010:48 amSTL - MDW

1 stop11h 24mFrontier

Thu 1/13:10 pmMDW - STL

1 stop7h 23mFrontier

Deal found 12/16

$238

Tue 12/3010:48 amSTL - ORD

1 stop11h 36mFrontier

Thu 1/111:28 amORD - STL

1 stop11h 05mFrontier

Deal found 12/16

$238

Fri 12/266:34 pmCOU - ORD

Nonstop1h 36mUnited Airlines

Sun 1/41:00 pmORD - COU

Nonstop1h 35mUnited Airlines

Deal found 12/16

$239

Tue 12/237:03 amSGF - ORD

Nonstop1h 47mAmerican Airlines

Sun 1/48:00 amORD - SGF

Nonstop1h 57mAmerican Airlines

Deal found 12/16

$249

Wed 12/315:00 amSTL - ORD

1 stop5h 45mAmerican Airlines

Thu 1/17:07 amORD - STL

Nonstop1h 28mAmerican Airlines

Deal found 12/17

$255

Thu 12/2510:42 amSTL - ORD

1 stop7h 51mFrontier

Wed 12/3111:23 amORD - STL

1 stop11h 10mFrontier

Deal found 12/16

$257

Best flights from Missouri to Illinois
Discover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Mon 1/125:11 pmSTL - ORD

1 stop20h 02mMultiple Airlines

Thu 1/227:41 pmORD - STL

1 stop23h 03mMultiple Airlines

Deal found 12/17

$161

Tue 1/209:57 amSTL - ORD

Nonstop1h 35mUnited Airlines

Thu 1/221:00 pmORD - STL

Nonstop1h 30mUnited Airlines

Deal found 12/16

$162

Sat 1/107:40 amSTL - MDW

Nonstop1h 10mSouthwest

Sat 1/103:55 pmMDW - STL

Nonstop1h 15mSouthwest

Deal found 12/17

$171

Mon 1/126:44 pmSTL - ORD

Nonstop1h 31mAmerican Airlines

Thu 1/2211:40 amORD - STL

Nonstop1h 23mAmerican Airlines

Deal found 12/16

$171

Wed 1/216:35 amSTL - ORD

1 stop6h 43mDelta

Sat 1/3110:35 amORD - STL

1 stop6h 02mDelta

Deal found 12/16

$182

Fri 2/68:41 pmMCI - STL

1 stop18h 05mFrontier

Sun 2/812:03 pmSTL - MCI

1 stop7h 48mFrontier

Deal found 12/17

$248

Tue 1/64:49 pmSTL - ORD

Nonstop1h 43mUnited Airlines

Thu 1/89:25 pmORD - STL

Nonstop1h 33mUnited Airlines

Deal found 12/16

$162

Sat 1/105:50 pmSTL - MDW

Nonstop1h 10mSouthwest

Mon 1/129:55 amMDW - STL

Nonstop1h 20mSouthwest

Deal found 12/17

$171

Fri 2/2010:07 amCOU - ORD

Nonstop1h 31mAmerican Airlines

Sun 2/228:05 amORD - COU

Nonstop1h 31mAmerican Airlines

Deal found 12/16

$179

Wed 1/216:10 amSTL - ORD

1 stop5h 37mDelta

Thu 1/221:58 pmORD - STL

1 stop6h 45mDelta

Deal found 12/16

$182

Tue 1/61:10 pmSTL - MDW

Nonstop1h 05mSouthwest

Thu 1/89:55 amMDW - STL

Nonstop1h 20mSouthwest

Deal found 12/16

$171

Mon 1/124:49 pmSTL - ORD

Nonstop1h 43mUnited Airlines

Thu 1/221:00 pmORD - STL

Nonstop1h 30mUnited Airlines

Deal found 12/17

$171

Tue 1/133:25 pmCOU - ORD

Nonstop1h 30mAmerican Airlines

Tue 1/201:24 pmORD - COU

Nonstop1h 31mAmerican Airlines

Deal found 12/15

$179

Tue 1/276:00 amSTL - ORD

1 stop7h 40mDelta

Thu 1/298:50 amORD - STL

1 stop5h 48mDelta

Deal found 12/16

$182

Tue 1/202:15 pmSTL - MDW

1 stop4h 35mSouthwest

Thu 1/227:45 pmMDW - STL

Nonstop1h 15mSouthwest

Deal found 12/16

$172

Mon 4/278:00 amCOU - ORD

Nonstop1h 33mUnited Airlines

Sat 5/167:35 pmORD - COU

Nonstop1h 35mUnited Airlines

Deal found 12/17

$179

Fri 1/911:56 amCOU - ORD

Nonstop1h 33mAmerican Airlines

Sun 1/117:40 pmORD - COU

Nonstop1h 30mAmerican Airlines

Deal found 12/16

$179

Mon 1/196:40 pmSTL - MDW

Nonstop1h 10mSouthwest

Wed 1/216:00 amMDW - STL

1 stop4h 15mSouthwest

Deal found 12/17

$172

Wed 2/184:39 pmMCI - STL

2 stops31h 20mMultiple Airlines

Mon 2/2310:11 pmSTL - MCI

1 stop25h 22mMultiple Airlines

Deal found 12/16

$236

Thu 1/83:10 pmCOU - ORD

Nonstop1h 36mUnited Airlines

Sat 1/103:44 pmORD - COU

Nonstop1h 35mUnited Airlines

Deal found 12/17

$179

Thu 1/86:00 amCOU - ORD

Nonstop1h 36mAmerican Airlines

Sun 1/117:40 pmORD - COU

Nonstop1h 30mAmerican Airlines

Deal found 12/17

$179

Wed 2/185:11 pmSGF - MDW

1 stop5h 31mDelta

Wed 2/256:00 amMDW - SGF

1 stop5h 18mDelta

Deal found 12/15

$209

Tue 1/1311:17 amCOU - ORD

Nonstop1h 36mUnited Airlines

Tue 1/207:58 pmORD - COU

Nonstop1h 39mUnited Airlines

Deal found 12/15

$179

Mon 4/274:31 pmCOU - ORD

Nonstop1h 29mAmerican Airlines

Sat 5/166:30 pmORD - COU

Nonstop1h 27mAmerican Airlines

Deal found 12/18

$179

Tue 1/136:10 amMCI - STL

Nonstop1h 15mSouthwest

Thu 1/228:15 amSTL - MCI

1 stop6h 05mSouthwest

Deal found 12/15

$181

Wed 1/145:00 pmSGF - MDW

1 stop5h 07mDelta

Wed 1/2110:46 amMDW - SGF

1 stop5h 29mDelta

Deal found 12/15

$209

Fri 2/2711:26 amMCI - MDW

2 stops11h 08mMultiple Airlines

Sun 3/19:04 pmMDW - MCI

1 stop12h 56mMultiple Airlines

Deal found 12/15

$260

Fri 1/168:09 amCOU - ORD

Nonstop1h 46mUnited Airlines

Mon 1/199:00 amORD - COU

Nonstop1h 42mUnited Airlines

Deal found 12/17

$179

Wed 1/148:20 amSTL - MDW

Nonstop1h 10mSouthwest

Thu 1/1512:30 pmMDW - STL

1 stop5h 25mSouthwest

Deal found 12/17

$181

Wed 1/1412:01 pmSGF - ORD

1 stop4h 44mDelta

Wed 1/215:30 amORD - SGF

1 stop5h 50mDelta

Deal found 12/15

$209

Last-minute flights from Missouri to Illinois
Discover last-minute flight deals from Missouri to Illinois. Data last updated December 18, 2025 and is based on user searches.

Tue 1/63:05 pmSTL - MDW

1 stop5h 00mSouthwest

Thu 1/87:45 pmMDW - STL

Nonstop1h 15mSouthwest

Deal found 12/16

$172

Thu 1/83:43 pmSTL - ORD

1 stop6h 56mMultiple Airlines

Mon 1/126:57 pmORD - STL

2 stops35h 54mMultiple Airlines

Deal found 12/17

$156

Thu 1/83:43 pmSTL - MDW

1 stop6h 34mFrontier

Mon 1/124:31 pmMDW - STL

1 stop30h 03mFrontier

Deal found 12/17

$158

Thu 1/88:20 amSTL - MDW

Nonstop1h 10mSouthwest

Mon 1/121:50 pmMDW - STL

Nonstop1h 10mSouthwest

Deal found 12/16

$171

Thu 1/88:05 amSTL - ORD

Nonstop1h 35mUnited Airlines

Thu 1/151:00 pmORD - STL

Nonstop1h 30mUnited Airlines

Deal found 12/17

$171

Mon 1/125:11 pmSTL - ORD

1 stop20h 02mMultiple Airlines

Thu 1/227:41 pmORD - STL

1 stop23h 03mMultiple Airlines

Deal found 12/17

$161

Tue 1/135:11 pmSTL - ORD

1 stop20h 02mMultiple Airlines

Fri 1/164:41 pmORD - STL

1 stop14h 10mMultiple Airlines

Deal found 12/17

$149

Wed 1/145:55 pmSTL - MDW

Nonstop1h 10mSouthwest

Thu 1/158:30 pmMDW - STL

Nonstop1h 15mSouthwest

Deal found 12/17

$162

Tue 1/205:42 pmSTL - ORD

1 stop19h 31mMultiple Airlines

Thu 1/224:19 pmORD - STL

2 stops18h 04mMultiple Airlines

Deal found 12/16

$163

Wed 1/218:22 pmSTL - ORD

1 stop17h 15mFrontier

Fri 1/2312:07 pmORD - STL

1 stop26h 39mFrontier

Deal found 12/16

$158

Wed 1/216:00 amSTL - ORD

Nonstop1h 27mAmerican Airlines

Sat 1/3111:40 amORD - STL

Nonstop1h 29mAmerican Airlines

Deal found 12/16

$162

Thu 1/225:42 pmSTL - ORD

1 stop16h 53mFrontier

Tue 1/272:53 pmORD - STL

1 stop15h 58mFrontier

Deal found 12/17

$146

One-way flights from Missouri to Illinois
Search for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Fri 1/168:27 pmMCI - STL

1 stop18h 21mFrontier

Deal found 12/17

$64

Mon 1/125:11 pmSTL - ORD

1 stop24h 41mMultiple Airlines

Deal found 12/17

$68

Mon 1/198:32 pmSTL - ORD

1 stop17h 25mFrontier

Deal found 12/17

$69

Fri 1/308:41 pmMCI - STL

1 stop18h 05mFrontier

Deal found 12/16

$71

Wed 2/183:49 pmSTL - MDW

1 stop22h 37mFrontier

Deal found 12/17

$74

Wed 2/183:49 pmSTL - ORD

1 stop18h 57mFrontier

Deal found 12/16

$74

Thu 1/1511:26 amMCI - ORD

1 stop9h 31mMultiple Airlines

Deal found 12/15

$76

Wed 1/73:25 pmMCI - STL

1 stop5h 10mSouthwest

Deal found 12/17

$77

Tue 1/131:10 pmSTL - MDW

Nonstop1h 05mSouthwest

Deal found 12/17

$77

Wed 3/117:40 amSTL - ORD

Nonstop1h 29mUnited Airlines

Deal found 12/16

$77

Wed 1/76:15 pmMCI - ORD

1 stop17h 07mSpirit Airlines

Deal found 12/16

$78

Sun 1/115:11 pmSTL - MDW

1 stop29h 58mFrontier

Deal found 12/17

$79

Find flight deals from Missouri to Illinois

Most accurate provider	Justfly.com 3 stars
Most trusted provider	Justfly.com 3 stars
Round-trip from	$146 (Kiwi.com)
One-way from	$64 (Trip.com)
Popular in	December
Cheapest in	August
Average price	$333
Good round-trip deal	$169 or less
Good one-way deal	$184 or less

Provider with most accurate pricing for Lambert-St Louis-Chicago (CHI) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Chicago (CHI) flights.

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From Missouri to Illinois

Search Deals

One-way flight from Missouri to Illinois

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($28 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to Illinois.

Search Deals

Price to beat on a one-way flight from Missouri to Illinois.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 1/12

5:11 pm-1:13 pm

1 stop20h 02m

Chicago O'Hare Intl

Thu 1/22

7:41 pm-6:44 pm

1 stop23h 03m

$161

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 1/20

9:57 am-11:32 am

Nonstop1h 35m

Chicago O'Hare Intl

Thu 1/22

1:00 pm-2:30 pm

Nonstop1h 30m

$162

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 1/6

4:49 pm-6:32 pm

Nonstop1h 43m

Chicago O'Hare Intl

Thu 1/8

9:25 pm-10:58 pm

Nonstop1h 33m

$162

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Sat 1/10

7:40 am-8:50 am

Nonstop1h 10m

Chicago Midway

Sat 1/10

3:55 pm-5:10 pm

Nonstop1h 15m

$171

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 1/12

6:44 pm-8:15 pm

Nonstop1h 31m

Chicago O'Hare Intl

Thu 1/22

11:40 am-1:03 pm

Nonstop1h 23m

$171

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Sat 1/10

5:50 pm-7:00 pm

Nonstop1h 10m

Chicago Midway

Mon 1/12

9:55 am-11:15 am

Nonstop1h 20m

$171

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Tue 1/6

1:10 pm-2:15 pm

Nonstop1h 05m

Chicago Midway

Thu 1/8

9:55 am-11:15 am

Nonstop1h 20m

$171

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 1/12

4:49 pm-6:32 pm

Nonstop1h 43m

Chicago O'Hare Intl

Thu 1/22

1:00 pm-2:30 pm

Nonstop1h 30m

$171

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Tue 1/20

2:15 pm-6:50 pm

1 stop4h 35m

Chicago Midway

Thu 1/22

7:45 pm-9:00 pm

Nonstop1h 15m

$172

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Mon 1/19

6:40 pm-7:50 pm

Nonstop1h 10m

Chicago Midway

Wed 1/21

6:00 am-10:15 am

1 stop4h 15m

$172

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Illinois

What is the cheapest month to book a flight from Missouri to Illinois?

Currently, September is the cheapest month in which you can book a flight from Missouri to Illinois (average of $62). Flying from Missouri to Illinois in August is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IL?

When flying from Missouri to Illinois, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 25% versus a flight at noon.

What is the cheapest day to fly from Missouri to Illinois?

Travelers seeking maximum savings on their Missouri to Illinois flight should consider departing on Saturday mornings when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Illinois

Read reviews from past customers who have flown Southwest, Contour, and United Airlines from Missouri to Illinois. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Contour

7.6

Good

43 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,092 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,055 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southern / Mokulele

6.8

Okay

30 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Missouri to Illinois?
Departing from Missouri to Illinois will take you 1h 10m. The distance between Missouri and Illinois is about 251 mi. Most flights are nonstop.
Can I find deals for flights from Missouri to Illinois that include hotel bookings?
Yes. In addition to deals on Missouri to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Illinois?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Illinois.
Can I find deals for business class flights from Missouri to Illinois?
Yes. Cheapflights offers flight deals from Missouri to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Illinois?
Currently, September is the cheapest month in which you can book a flight from Missouri to Illinois (average of $62). Flying from Missouri to Illinois in August is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Missouri to Illinois

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$97	Average$326	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$106	Average$293	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$114	Average$339	FlexibilityNo cancel fee	On-time69%
Contour	Cheapest$123	Average$159	FlexibilityNo cancel fee	On-timeN/A
Southern / Mokulele	Cheapest$140	Average$215	FlexibilityNo cancel fee	On-timeN/A

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$64+ Cheap flights from Missouri to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Illinois with Cheapflights

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Cheap flight deals from Missouri to Illinois

Cheapest flights from Missouri to IllinoisExplore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Illinois

Keep the following information in mind while searching for Missouri to Illinois flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Illinois that are best for you.

Best time to book a flight from Missouri to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Illinois

What is the cheapest month to book a flight from Missouri to Illinois?

What is the cheapest time of day to fly from MO to IL?

Find hourly flight availability from Missouri to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

What is the cheapest day to fly from Missouri to Illinois?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Illinois. Price data was last updated on December 13, 2025.

Reviews of airlines servicing Illinois

Read reviews from past customers who have flown Southwest, Contour, and United Airlines from Missouri to Illinois. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Illinois?

Can I find deals for flights from Missouri to Illinois that include hotel bookings?

How can I find direct flights from Missouri to Illinois?

Can I find deals for business class flights from Missouri to Illinois?

What is the cheapest month to book a flight from Missouri to Illinois?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Illinois

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Missouri to Illinois

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Cheapest flights from Missouri to Illinois
Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.