$49+ Cheap flights from Missouri to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ORD
Apr 15 — Apr 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Illinois with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Illinois
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to IllinoisExplore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Sun 3/2912:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/11![Contour logo]()
$120
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Mon 3/3012:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/11![Contour logo]()
$121
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sat 4/1812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/12![Contour logo]()
$123
This Contour deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sun 7/512:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/14![Contour logo]()
$139
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Wed 9/23:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/16![Contour logo]()
$163
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 4/611:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/12![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Mon 4/610:34 pm
ORD
- STL
Nonstop1h 31m
American Airlines
Deal found 3/11![American Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- ORD
1 stop14h 00m
Multiple Airlines
Wed 5/61:59 pm
ORD
- STL
1 stop26h 55m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$172
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:51 am
STL
- ORD
Nonstop1h 30m
American Airlines
Sat 4/117:02 am
ORD
- STL
Nonstop1h 25m
American Airlines
Deal found 3/11![American Airlines logo]()
$173
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:39 pm
STL
- ORD
1 stop6h 38m
Delta
Sat 4/49:50 am
ORD
- STL
1 stop6h 50m
Delta
Deal found 3/11![Delta logo]()
$174
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Tue 4/2812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/15![Contour logo]()
$177
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:48 am
STL
- MDW
1 stop5h 55m
Delta
Tue 4/147:16 pm
MDW
- STL
1 stop3h 58m
Delta
Deal found 3/12![Delta logo]()
$177
Best flights from Missouri to IllinoisDiscover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
Discover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sat 4/1812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/12![Contour logo]()
$123
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Sat 4/410:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/11![Southwest logo]()
$171
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:21 am
STL
- ORD
2 stops6h 40m
Delta
Wed 5/277:00 am
ORD
- STL
1 stop6h 10m
Delta
Deal found 3/12![Delta logo]()
$182
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:45 am
STL
- ORD
Nonstop1h 26m
United Airlines
Tue 4/217:00 am
ORD
- STL
Nonstop1h 25m
United Airlines
Deal found 3/11![United Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 pm
SGF
- ORD
Nonstop1h 49m
American Airlines
Tue 4/73:43 pm
ORD
- SGF
Nonstop1h 52m
American Airlines
Deal found 3/13![American Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/812:24 pm
MCI
- STL
2 stops29h 10m
Multiple Airlines
Wed 4/158:23 pm
STL
- MCI
1 stop14h 35m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$276
This Contour deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sun 7/512:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/14![Contour logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:46 pm
MCI
- STL
1 stop13h 02m
Frontier
Thu 4/169:55 pm
STL
- MCI
2 stops15h 35m
Frontier
Deal found 3/12![Frontier logo]()
$314
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Thu 4/169:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/11![Southwest logo]()
$171
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Wed 9/23:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/16![Contour logo]()
$163
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:10 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 4/610:15 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/14![Southwest logo]()
$191
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Tue 4/2812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/14![Contour logo]()
$177
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 4/1910:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Deal found 3/12![United Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Wed 5/610:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/15![Southwest logo]()
$191
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Thu 4/1610:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Deal found 3/12![United Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Sun 4/195:00 am
ORD
- COU
1 stop6h 35m
American Airlines
Deal found 3/13![American Airlines logo]()
$244
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:00 pm
SGF
- MDW
1 stop5h 45m
Delta
Wed 7/85:25 pm
MDW
- SGF
1 stop5h 10m
Delta
Deal found 3/12![Delta logo]()
$249
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/299:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Thu 4/212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/13![Contour logo]()
$194
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Mon 7/610:57 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 3/11![United Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Sat 4/253:00 pm
MDW
- STL
1 stop7h 25m
Southwest
Deal found 3/13![Southwest logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:45 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Thu 4/309:44 pm
ORD
- CGI
1 stop22h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 pm
SGF
- ORD
Nonstop1h 49m
American Airlines
Sun 4/53:16 pm
ORD
- SGF
1 stop6h 43m
American Airlines
Deal found 3/11![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:35 am
STL
- MDW
1 stop6h 40m
Southwest
Mon 5/185:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/14![Southwest logo]()
$201
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sun 5/1712:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/11![Contour logo]()
$206
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:23 am
SGF
- ORD
Nonstop1h 52m
United Airlines
Sat 4/188:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Deal found 3/12![United Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Sat 6/65:00 am
ORD
- COU
1 stop6h 14m
American Airlines
Deal found 3/15![American Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:32 am
STL
- ORD
1 stop6h 45m
Delta
Sat 4/49:50 am
ORD
- STL
1 stop6h 50m
Delta
Deal found 3/11![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Sun 4/58:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Deal found 3/11![United Airlines logo]()
$229
This Trip.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Mon 4/1312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/13![Contour logo]()
$220
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:15 am
STL
- ORD
1 stop6h 14m
Delta
Sun 5/319:10 am
ORD
- STL
1 stop4h 00m
Delta
Deal found 3/12![Delta logo]()
$294
Last-minute flights from Missouri to IllinoisDiscover last-minute flight deals from Missouri to Illinois. Data last updated March 16, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Illinois. Data last updated March 16, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Sun 3/2912:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/11![Contour logo]()
$120
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Mon 3/3012:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/11![Contour logo]()
$121
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:39 pm
STL
- ORD
1 stop6h 38m
Delta
Sat 4/49:50 am
ORD
- STL
1 stop6h 50m
Delta
Deal found 3/11![Delta logo]()
$174
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 4/611:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/12![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Mon 4/610:34 pm
ORD
- STL
Nonstop1h 31m
American Airlines
Deal found 3/11![American Airlines logo]()
$171
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:59 pm
STL
- ORD
1 stop6h 37m
Frontier
Mon 4/134:21 pm
ORD
- STL
1 stop7h 04m
Frontier
Deal found 3/16![Frontier logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:16 pm
STL
- ORD
1 stop28h 22m
Frontier
Wed 4/156:08 pm
ORD
- STL
1 stop16h 22m
Frontier
Deal found 3/13![Frontier logo]()
$178
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Sat 4/1812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/12![Contour logo]()
$123
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Tue 4/2812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/15![Contour logo]()
$177
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:48 am
STL
- MDW
1 stop5h 55m
Delta
Tue 4/147:16 pm
MDW
- STL
1 stop3h 58m
Delta
Deal found 3/12![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:48 am
STL
- ORD
1 stop5h 57m
Delta
Tue 4/145:04 pm
ORD
- STL
1 stop3h 40m
Delta
Deal found 3/12![Delta logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- ORD
1 stop14h 00m
Multiple Airlines
Wed 5/61:59 pm
ORD
- STL
1 stop26h 55m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$172
One-way flights from Missouri to IllinoisSearch for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
Search for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:50 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 3/11![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:45 am
STL
- ORD
Nonstop1h 26m
United Airlines
Deal found 3/12![United Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 3/11![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:33 pm
STL
- MDW
1 stop27h 29m
Frontier
Deal found 3/12![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:33 pm
STL
- ORD
1 stop13h 22m
Frontier
Deal found 3/12![Frontier logo]()
$76
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:10 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/12![United Airlines logo]()
$78
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/12![Southwest logo]()
$79
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:09 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 3/12![United Airlines logo]()
$79
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:21 am
STL
- MDW
2 stops6h 21m
Delta
Deal found 3/12![Delta logo]()
$84
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:53 am
STL
- ORD
2 stops9h 12m
Delta
Deal found 3/12![Delta logo]()
$84
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/12![Southwest logo]()
$86
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:10 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/12![United Airlines logo]()
$86
Find flight deals from Missouri to Illinois
Keep the following information in mind while searching for Missouri to Illinois flight deals. Data was last updated March 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $120 (Mytrip) |
One-way from | $49 (Southwest) |
Popular in | January |
Cheapest in | August |
Average price | $310 |
Good round-trip deal | $118 or less |
Good one-way deal | $59 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Missouri to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Cape GirardeauChicago
CGI - ORD
CGIORD
Cape Girardeau
Sat 4/11
9:45 am-11:30 am
Nonstop1h 45m
Chicago O'Hare Intl
Sat 4/18
12:10 pm-1:50 pm
Nonstop1h 40m
$123
Cape GirardeauChicago
CGI - ORD
CGIORD
Cape Girardeau
Fri 7/3
9:45 am-11:30 am
Nonstop1h 45m
Chicago O'Hare Intl
Sun 7/5
12:10 pm-1:50 pm
Nonstop1h 40m
$139
Cape GirardeauChicago
CGI - ORD
CGIORD
Cape Girardeau
Tue 9/1
9:45 am-11:30 am
Nonstop1h 45m
Chicago O'Hare Intl
Wed 9/2
3:55 pm-5:35 pm
Nonstop1h 40m
$163
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Thu 4/2
5:30 am-6:40 am
Nonstop1h 10m
Chicago Midway
Sat 4/4
10:15 am-11:30 am
Nonstop1h 15m
$171
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Thu 4/9
7:20 am-8:30 am
Nonstop1h 10m
Chicago Midway
Thu 4/16
9:00 am-10:15 am
Nonstop1h 15m
$171
Cape GirardeauChicago
CGI - ORD
CGIORD
Cape Girardeau
Tue 4/14
9:45 am-11:30 am
Nonstop1h 45m
Chicago O'Hare Intl
Tue 4/28
12:10 pm-1:50 pm
Nonstop1h 40m
$177
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Wed 5/20
6:21 am-1:01 pm
2 stops6h 40m
Chicago O'Hare Intl
Wed 5/27
7:00 am-1:10 pm
1 stop6h 10m
$182
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Sat 4/4
5:10 am-6:20 am
Nonstop1h 10m
Chicago Midway
Mon 4/6
10:15 pm-11:30 pm
Nonstop1h 15m
$191
Quickest round-trip
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Wed 4/29
8:45 pm-9:50 pm
Nonstop1h 05m
Chicago Midway
Wed 5/6
10:15 am-11:30 am
Nonstop1h 15m
$191
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Sat 4/18
7:45 am-9:11 am
Nonstop1h 26m
Chicago O'Hare Intl
Tue 4/21
7:00 am-8:25 am
Nonstop1h 25m
$194
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Missouri with our price prediction graph.
CGI-ORD
STL-MDW
STL-ORD
MCI-STL
COU-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Illinois
USMO-USIL
CGI-ORD
STL-MDW
STL-ORD
MCI-STL
What is the cheapest month to book a flight from Missouri to Illinois?
Currently, September is the cheapest month in which you can book a flight from Missouri to Illinois (average of $62). Flying from Missouri to Illinois in January is currently the most expensive (average of $156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to IL?
Find hourly flight availability from Missouri to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.
When flying from Missouri to Illinois, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 34% versus a flight in the evening.
What is the cheapest day to fly from Missouri to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Illinois. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Missouri to Illinois flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to Illinois
Explore weekly flight availability from Missouri to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 16, 2026.
The most flights from USMO to USIL are scheduled on a Sunday (69 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (30 on average).
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated March 16, 2026.
Read reviews from past customers who have flown Southwest,Contour, andUnited Airlines from Missouri to Illinois. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Missouri to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Missouri to Illinois
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Illinois by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Illinois by cabin class
Find flights from Missouri to Illinois, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Illinois flights
Browse other Missouri and Illinois flight options. Last updated on March 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Illinois
Find the right flight back to Missouri after your stay in Illinois
Missouri to Illinois flights
Consider these flights traveling from Missouri to Illinois.
Top 6 airlines flying from Missouri to Illinois
Discover the top 6 airlines that operate flights from Missouri to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$300 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$117 | Average$361 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$117 | Average$334 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$118 | Average$160 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$140 | Average$198 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$143 | Average$176 | FlexibilityNo cancel fee | On-time62% |