$40+ Cheap flights from Missouri to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ORD
Mar 5 — Mar 121
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to IllinoisExplore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Tue 3/107:41 pm
ORD
- STL
1 stop14h 56m
Frontier
Deal found 2/3![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- MDW
1 stop6h 38m
Frontier
Fri 3/136:05 am
MDW
- STL
1 stop7h 29m
Frontier
Deal found 2/2![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
1 stop9h 30m
Frontier
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Frontier
Deal found 2/2![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- MDW
2 stops18h 57m
Frontier
Sun 3/19:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/2![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Multiple Airlines
Mon 2/236:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$169
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- ORD
1 stop14h 34m
Multiple Airlines
Thu 3/57:23 pm
ORD
- STL
2 stops16h 26m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
2 stops11h 31m
Multiple Airlines
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$185
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Tue 4/78:04 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Deal found 2/3![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Frontier
Sun 2/225:05 am
ORD
- STL
1 stop25h 46m
Frontier
Deal found 2/2![Frontier logo]()
$191
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Sun 2/228:02 am
ORD
- COU
Nonstop1h 28m
American Airlines
Deal found 2/1![American Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:00 am
MCI
- STL
1 stop5h 25m
Southwest
Mon 5/43:50 pm
STL
- MCI
Nonstop1h 10m
Southwest
Deal found 2/1![Southwest logo]()
$195
Best flights from Missouri to IllinoisDiscover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:10 pm
COU
- ORD
Nonstop1h 30m
United Airlines
Tue 3/109:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:00 am
MCI
- STL
1 stop5h 25m
Southwest
Mon 5/43:50 pm
STL
- MCI
Nonstop1h 10m
Southwest
Deal found 2/1![Southwest logo]()
$195
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:34 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Fri 2/278:00 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:32 pm
SGF
- ORD
1 stop6h 24m
Delta
Mon 3/911:10 am
ORD
- SGF
1 stop7h 01m
Delta
Deal found 1/31![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:40 pm
MCI
- ORD
1 stop12h 03m
Multiple Airlines
Tue 3/1012:44 pm
ORD
- MCI
1 stop26h 45m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$209
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:15 pm
MCI
- STL
1 stop4h 57m
Frontier
Thu 5/78:12 pm
STL
- MCI
1 stop17h 18m
Frontier
Deal found 2/2![Frontier logo]()
$213
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/142:41 pm
COU
- ORD
Nonstop1h 28m
United Airlines
Tue 3/179:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:50 pm
MCI
- STL
1 stop4h 50m
Southwest
Thu 5/78:30 am
STL
- MCI
Nonstop1h 10m
Southwest
Deal found 2/2![Southwest logo]()
$203
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:32 pm
SGF
- MDW
1 stop4h 59m
Delta
Mon 3/99:35 am
MDW
- SGF
2 stops8h 36m
Delta
Deal found 1/31![Delta logo]()
$214
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:23 pm
COU
- ORD
Nonstop1h 33m
United Airlines
Sun 4/51:16 pm
ORD
- COU
Nonstop1h 32m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Sat 5/167:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Deal found 2/3![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:12 pm
STL
- ORD
1 stop12h 31m
Multiple Airlines
Sun 3/157:17 am
ORD
- STL
2 stops30h 17m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$225
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:55 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Sat 4/187:55 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- MDW
2 stops18h 59m
Frontier
Sun 2/229:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/2![Frontier logo]()
$236
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:37 am
MCI
- ORD
1 stop6h 06m
Delta
Sat 4/1812:14 pm
ORD
- MCI
2 stops8h 31m
Delta
Deal found 2/1![Delta logo]()
$216
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Tue 4/73:35 pm
ORD
- SGF
Nonstop1h 49m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:12 pm
STL
- ORD
1 stop12h 31m
Frontier
Sat 3/147:39 pm
ORD
- STL
2 stops38h 10m
Frontier
Deal found 2/3![Frontier logo]()
$236
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2110:37 am
MCI
- ORD
1 stop5h 41m
Delta
Tue 3/247:10 am
ORD
- MCI
2 stops8h 29m
Delta
Deal found 2/1![Delta logo]()
$216
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:20 am
MCI
- ORD
1 stop7h 55m
Southwest
Sat 4/182:05 pm
ORD
- MCI
1 stop6h 30m
Southwest
Deal found 2/1![Southwest logo]()
$225
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:00 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Sat 5/168:45 am
ORD
- SGF
Nonstop1h 51m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:02 am
MCI
- STL
1 stop4h 26m
American Airlines
Sat 2/2810:43 am
STL
- MCI
1 stop4h 51m
American Airlines
Deal found 2/1![American Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Sun 5/177:57 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:25 am
MCI
- MDW
1 stop3h 20m
Southwest
Mon 3/911:40 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:49 pm
STL
- MDW
1 stop22h 37m
Frontier
Sun 3/19:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/1![Frontier logo]()
$260
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:32 pm
SGF
- ORD
1 stop6h 24m
Delta
Sat 2/216:45 am
ORD
- SGF
1 stop5h 24m
Delta
Deal found 2/1![Delta logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/149:41 am
STL
- ORD
1 stop8h 05m
Multiple Airlines
Mon 2/166:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:30 am
COU
- ORD
Nonstop1h 30m
United Airlines
Mon 5/181:00 pm
ORD
- COU
Nonstop1h 32m
United Airlines
Deal found 2/1![United Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/71:36 pm
STL
- ORD
1 stop6h 04m
American Airlines
Sun 3/87:15 am
ORD
- STL
Nonstop1h 23m
American Airlines
Deal found 2/1![American Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/254:39 pm
MCI
- STL
2 stops31h 20m
Frontier
Sat 2/288:17 pm
STL
- MCI
1 stop13h 41m
Frontier
Deal found 2/1![Frontier logo]()
$263
Last-minute flights from Missouri to IllinoisDiscover last-minute flight deals from Missouri to Illinois. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Illinois. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Multiple Airlines
Mon 2/236:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Frontier
Sun 2/225:05 am
ORD
- STL
1 stop25h 46m
Frontier
Deal found 2/2![Frontier logo]()
$191
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Sun 2/228:02 am
ORD
- COU
Nonstop1h 28m
American Airlines
Deal found 2/1![American Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:28 am
SGF
- ORD
Nonstop1h 42m
American Airlines
Sat 2/288:10 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- MDW
2 stops18h 57m
Frontier
Sun 3/19:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/2![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- ORD
1 stop14h 29m
Frontier
Sun 3/14:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Deal found 2/2![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Tue 3/107:41 pm
ORD
- STL
1 stop14h 56m
Frontier
Deal found 2/3![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- ORD
1 stop14h 34m
Multiple Airlines
Thu 3/57:23 pm
ORD
- STL
2 stops16h 26m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- MDW
1 stop6h 38m
Frontier
Fri 3/136:05 am
MDW
- STL
1 stop7h 29m
Frontier
Deal found 2/2![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
1 stop9h 30m
Frontier
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Frontier
Deal found 2/2![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
2 stops11h 31m
Multiple Airlines
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$185
One-way flights from Missouri to IllinoisSearch for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/1![Southwest logo]()
$40
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:41 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/1![United Airlines logo]()
$46
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:35 am
STL
- MDW
1 stop4h 10m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:10 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/3![Southwest logo]()
$59
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:10 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/3![United Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Deal found 2/1![Frontier logo]()
$60
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:30 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/2![Southwest logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/98:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/1![Frontier logo]()
$67
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:35 am
STL
- ORD
1 stop8h 25m
Southwest
Deal found 2/3![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/2![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:00 am
MCI
- ORD
1 stop23h 51m
Frontier
Deal found 2/1![Frontier logo]()
$74
Find flight deals from Missouri to Illinois
Keep the following information in mind while searching for Missouri to Illinois flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $118 (Kiwi.com) |
One-way from | $40 (Southwest) |
Popular in | December |
Cheapest in | August |
Average price | $245 |
Good round-trip deal | $158 or less |
Good one-way deal | $69 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Illinois that are best for you.
Fly from
Missouri
Fly to
Illinois
Route
Depart
Return
Price
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Tue 3/3
3:10 pm-4:40 pm
Nonstop1h 30m
Chicago O'Hare Intl
Tue 3/10
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Wed 2/25
11:15 am-12:45 pm
Nonstop1h 30m
Chicago O'Hare Intl
Sun 3/1
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Sat 3/14
2:41 pm-4:09 pm
Nonstop1h 28m
Chicago O'Hare Intl
Tue 3/17
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 4/2
3:23 pm-4:56 pm
Nonstop1h 33m
Chicago O'Hare Intl
Sun 4/5
1:16 pm-2:48 pm
Nonstop1h 32m
$179
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Sat 4/4
6:30 pm-8:18 pm
Nonstop1h 48m
Chicago O'Hare Intl
Tue 4/7
3:35 pm-5:24 pm
Nonstop1h 49m
$189
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Mon 5/4
8:00 pm-9:43 pm
Nonstop1h 43m
Chicago O'Hare Intl
Sat 5/16
8:45 am-10:36 am
Nonstop1h 51m
$189
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Thu 5/14
8:00 pm-9:43 pm
Nonstop1h 43m
Chicago O'Hare Intl
Sun 5/17
7:57 pm-9:57 pm
Nonstop2h 00m
$189
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Fri 5/15
11:30 am-1:00 pm
Nonstop1h 30m
Chicago O'Hare Intl
Mon 5/18
1:00 pm-2:32 pm
Nonstop1h 32m
$194
Kansas CitySt. Louis
MCI - STL
MCISTL
Kansas City
Wed 4/29
8:00 am-1:25 pm
1 stop5h 25m
Lambert-St Louis
Mon 5/4
3:50 pm-5:00 pm
Nonstop1h 10m
$195
Kansas CitySt. Louis
MCI - STL
MCISTL
Kansas City
Mon 5/4
5:50 pm-10:40 pm
1 stop4h 50m
Lambert-St Louis
Thu 5/7
8:30 am-9:40 am
Nonstop1h 10m
$203
Showing 1-10 of 60 results
Best time to book a flight from Missouri to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Missouri with our price prediction graph.
STL-MDW
STL-ORD
MCI-MDW
MCI-ORD
COU-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Illinois
USMO-USIL
STL-MDW
STL-ORD
MCI-MDW
MCI-ORD
What is the cheapest month to book a flight from Missouri to Illinois?
Currently, September is the cheapest month in which you can book a flight from Missouri to Illinois (average of $62). Flying from Missouri to Illinois in January is currently the most expensive (average of $156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to IL?
Find hourly flight availability from Missouri to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
When flying from Missouri to Illinois, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 29% versus a flight at noon.
What is the cheapest day to fly from Missouri to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Illinois. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Missouri to Illinois flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to Illinois
Explore weekly flight availability from Missouri to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 3, 2026.
The most flights from USMO to USIL are scheduled on a Monday (58 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (30 on average).
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated February 3, 2026.
Read reviews from past customers who have flown Southwest, Contour, and United Airlines from Missouri to Illinois. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Missouri to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Missouri to Illinois
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Missouri to Illinois
Discover the top 5 airlines that operate flights from Missouri to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$298 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$114 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$117 | Average$351 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$123 | Average$161 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$140 | Average$203 | FlexibilityNo cancel fee | On-timeN/A |