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$305+ Cheap flights from Florence, SC (FLO) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Florence to Illinois

Best flights from Florence to Illinois
Discover carefully curated flight deals from Florence to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/165:36 pmFLO - STL
1 stop6h 36mAmerican Airlines
Sun 1/183:54 pmSTL - FLO
1 stop5h 49mAmerican Airlines
Deal found 12/26$355
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/105:36 pmFLO - ORD
1 stop6h 51mAmerican Airlines
Wed 1/1410:10 amORD - FLO
1 stop5h 59mAmerican Airlines
Deal found 12/25$457
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/115:36 pmFLO - ORD
1 stop6h 51mAmerican Airlines
Thu 1/153:21 pmORD - FLO
1 stop6h 22mAmerican Airlines
Deal found 12/26$457

Find flight deals from Florence to Illinois

Keep the following information in mind while searching for Florence to Illinois flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$355
(American Airlines)

One-way from

$305
(American Airlines)
Provider with most accurate pricing for Florence-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Chicago (CHI) flights.
Search Deals
From Florence to Illinois
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One-way flight from Florence to Illinois
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Florence to Illinois that are best for you.

Fly from

Florence

Fly to

Illinois

Route

Depart

Return

Price

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 1/16

5:36 pm-11:12 pm

1 stop6h 36m

Lambert-St Louis

Sun 1/18

3:54 pm-10:43 pm

1 stop5h 49m

$355

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 1/10

5:36 pm-11:27 pm

1 stop6h 51m

Chicago O'Hare Intl

Wed 1/14

10:10 am-5:09 pm

1 stop5h 59m

$457

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 1/11

5:36 pm-11:27 pm

1 stop6h 51m

Chicago O'Hare Intl

Thu 1/15

3:21 pm-10:43 pm

1 stop6h 22m

$457

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 1/6

5:36 pm-11:27 pm

1 stop6h 51m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Best time to book a flight from Florence to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Illinois

What is the cheapest month to book a flight from Florence, South Carolina to Illinois?

Currently, February is the cheapest month in which you can book a flight from Florence, South Carolina to Illinois (average of $57). Flying from Florence, South Carolina to Illinois in April is currently the most expensive (average of $125). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated December 28, 2025.
Read through reviews of airlines operating flights from Florence to Illinois, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Boarding

7.5

Crew

8.0

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.
American Airlines
7.2
Good
11,072 reviews
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Boarding

7.5

Crew

8.0

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.

Related info for your journey

Find useful and relevant information for your journey from Florence to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Illinois?

    Most people fly from Florence (FLO) if they book a flight from Florence to Illinois. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Illinois?

    American Airlines can get you from Florence, South Carolina to Illinois in just under 6h 36m. Your travel time can differ by up to . The distance between Florence, South Carolina and Illinois is about 669 mi.

  • What are the most popular routes from Florence, South Carolina to Illinois?

    When deciding which route to take from Florence, South Carolina to Illinois consider Florence - Chicago O'Hare Intl, Florence - Lambert-St Louis or Florence - Greater Peoria as they are the most popular.

  • Can I find deals for flights from Florence to Illinois that include hotel bookings?

    Yes. In addition to deals on Florence to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Illinois.

  • Can I find deals for business class flights from Florence to Illinois?

    Yes. Cheapflights offers flight deals from Florence to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Illinois?

    Currently, February is the cheapest month in which you can book a flight from Florence, South Carolina to Illinois (average of $57). Flying from Florence, South Carolina to Illinois in April is currently the most expensive (average of $125). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Florence to Illinois

Discover the top airline that operate flights from Florence to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$336FlexibilityNo cancel feeOn-time71%

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