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$229+ Cheap flights from Florence, SC (FLO) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Florence to Illinois

Cheapest flights from Florence to Illinois
Explore the most affordable flight options available from Florence to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:30 pmFLO - STL
1 stop6h 25mAmerican Airlines
Sat 1/35:00 amSTL - FLO
1 stop6h 42mAmerican Airlines
Deal found 11/5$272
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:15 amFLO - STL
2 stops12h 11mAmerican Airlines
Sat 1/37:05 amSTL - FLO
1 stop4h 37mAmerican Airlines
Deal found 11/5$277
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:35 pmFLO - STL
1 stop6h 31mAmerican Airlines
Mon 12/1510:13 amSTL - FLO
1 stop5h 57mAmerican Airlines
Deal found 11/5$283
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:15 amFLO - STL
1 stop4h 20mAmerican Airlines
Sat 1/37:05 amSTL - FLO
1 stop4h 37mAmerican Airlines
Deal found 11/5$307
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/261:07 pmFLO - STL
1 stop5h 17mAmerican Airlines
Sat 1/36:35 pmSTL - FLO
1 stop4h 40mAmerican Airlines
Deal found 11/5$331
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:31 pmFLO - ORD
1 stop6h 15mAmerican Airlines
Mon 12/153:44 pmORD - FLO
1 stop6h 09mAmerican Airlines
Deal found 11/4$393
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:15 amFLO - STL
2 stops9h 23mAmerican Airlines
Sun 1/46:00 amSTL - FLO
2 stops11h 05mAmerican Airlines
Deal found 11/5$422

Cheap flight deals from Florence to Illinois

Keep the following information in mind while searching for Florence to Illinois flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$272
(American Airlines)

One-way from

$229
(American Airlines)
Provider with most accurate pricing for Florence-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Chicago (CHI) flights.
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From Florence to Illinois
Search Deals
One-way flight from Florence to Illinois
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Florence to Illinois that are best for you.

Fly from

Florence

Fly to

Illinois

Route

Depart

Return

Price

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Tue 12/30

6:30 pm-11:55 pm

1 stop6h 25m

Lambert-St Louis

Sat 1/3

6:35 pm-12:15 am

1 stop4h 40m

$272

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Wed 12/31

12:51 pm-4:00 pm

1 stop4h 09m

Lambert-St Louis

Sat 1/3

5:00 am-12:42 pm

1 stop6h 42m

$272

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 12/12

5:35 pm-11:06 pm

1 stop6h 31m

Lambert-St Louis

Mon 12/15

10:13 am-5:10 pm

1 stop5h 57m

$283

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sat 12/27

5:15 am-8:35 am

1 stop4h 20m

Lambert-St Louis

Sat 1/3

7:05 am-12:42 pm

1 stop4h 37m

$307

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sat 12/27

6:30 pm-11:56 pm

1 stop6h 26m

Lambert-St Louis

Sun 1/4

7:05 am-12:42 pm

1 stop4h 37m

$331

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 1/16

6:15 am-11:35 am

1 stop6h 20m

Chicago O'Hare Intl

Tue 1/20

10:10 am-5:09 pm

1 stop5h 59m

$393

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 12/11

6:31 pm-11:46 pm

1 stop6h 15m

Chicago O'Hare Intl

Mon 12/15

3:44 pm-10:53 pm

1 stop6h 09m

$393

FlorencePeoria

FLO - PIA

FLOPIA

Florence

Wed 4/15

11:13 am-3:52 pm

1 stop5h 39m

Greater Peoria

Sat 4/18

5:19 am-10:02 am

1 stop3h 43m

$491

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 11/22

5:15 am-9:05 am

1 stop4h 50m

$229

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Mon 12/8

6:15 am-9:32 am

1 stop4h 17m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Best time to book a flight from Florence to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Illinois

What is the cheapest month to book a flight from Florence, South Carolina to Illinois?

Currently, February is the cheapest month in which you can book a flight from Florence, South Carolina to Illinois (average of $57). Flying from Florence, South Carolina to Illinois in April is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from Florence to Illinois, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,040 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.
American Airlines
7.2
Good
11,040 reviews
American Airlines
7.2
Good
11,040 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.

Related info for your journey

Find useful and relevant information for your journey from Florence to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Illinois?

    Most people fly from Florence (FLO) if they book a flight from Florence to Illinois. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Illinois?

    American Airlines can get you from Florence, South Carolina to Illinois in just under 6h 25m. Your travel time can differ by up to . The distance between Florence, South Carolina and Illinois is about 669 mi.

  • What are the most popular routes from Florence, South Carolina to Illinois?

    When deciding which route to take from Florence, South Carolina to Illinois consider Florence - Lambert-St Louis, Florence - Chicago O'Hare Intl or Florence - Greater Peoria as they are the most popular.

  • Can I find deals for flights from Florence to Illinois that include hotel bookings?

    Yes. In addition to deals on Florence to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Illinois.

  • Can I find deals for business class flights from Florence to Illinois?

    Yes. Cheapflights offers flight deals from Florence to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Illinois?

    Currently, February is the cheapest month in which you can book a flight from Florence, South Carolina to Illinois (average of $57). Flying from Florence, South Carolina to Illinois in April is currently the most expensive (average of $126). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Florence to Illinois

Discover the top airline that operate flights from Florence to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$372FlexibilityNo cancel feeOn-time71%

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