$115+ Cheap flights from Des Moines (DSM) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — HOU
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Houston are usually found in July or February, booked 65 days in advance, depart on a Monday or Tuesday and return on a Tuesday
Cheap flight deals from Des Moines to Houston
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Cheapest flights from Des Moines to HoustonExplore the most affordable flight options available from Des Moines to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Des Moines to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This CheapOair deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:30 pm -
1 stop13h 05m
Sun 9/2710:38 pm -
1 stop20h 55m
Deal found 9/2![Frontier logo]()
$232
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:29 am -
1 stop13h 14m
Fri 10/26:25 am -
1 stop13h 08m
Deal found 8/30![Frontier logo]()
$241
This CheapOair deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:30 pm -
1 stop13h 05m
Mon 9/2810:30 am -
1 stop9h 03m
Deal found 9/3![Frontier logo]()
$251
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
1 stop28h 15m
Mon 10/126:24 am -
1 stop13h 06m
Deal found 9/1![Frontier logo]()
$262
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop13h 22m
Sun 11/110:40 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$263
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm -
1 stop20h 15m
Thu 9/1010:38 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$264
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:29 am -
1 stop13h 14m
Sun 10/410:38 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$266
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:30 pm -
1 stop24h 18m
Thu 11/510:40 pm -
1 stop20h 55m
Deal found 8/30![Frontier logo]()
$268
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop28h 12m
Thu 11/510:40 pm -
1 stop20h 55m
Deal found 8/31![Frontier logo]()
$269
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop28h 13m
Sun 9/2010:38 pm -
1 stop20h 55m
Deal found 8/31![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:30 pm -
1 stop25h 25m
Sun 9/1310:38 pm -
1 stop20h 55m
Deal found 8/30![Frontier logo]()
$290
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:35 pm -
1 stop4h 55m
Fri 10/305:25 pm -
1 stop4h 55m
Deal found 8/31![Southwest logo]()
$314
Best flights from Des Moines to HoustonDiscover carefully curated flight deals from Des Moines to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Des Moines to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
Nonstop2h 24m
Mon 10/127:50 pm -
Nonstop2h 25m
Deal found 9/3![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:10 pm -
1 stop6h 45m
Fri 10/236:45 pm -
1 stop4h 30m
Deal found 9/1![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 am -
1 stop8h 24m
Sun 1/175:25 am -
1 stop6h 04m
Deal found 9/3![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/266:45 pm -
1 stop5h 29m
Fri 3/58:10 pm -
Nonstop2h 20m
Deal found 9/1![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 am -
1 stop8h 58m
Mon 11/166:15 am -
1 stop7h 53m
Deal found 9/3![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops8h 25m
Wed 11/46:30 am -
2 stops7h 45m
Deal found 9/3![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:25 pm -
2 stops11h 29m
Sun 10/45:40 am -
1 stop5h 06m
Deal found 9/3![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:25 am -
1 stop5h 10m
Mon 11/92:55 pm -
2 stops8h 05m
Deal found 9/2![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:34 pm -
1 stop8h 05m
Sun 9/276:00 am -
1 stop7h 49m
Deal found 9/1![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:10 pm -
1 stop6h 45m
Sun 10/116:15 am -
1 stop7h 20m
Deal found 8/31![Southwest logo]()
$398
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:10 pm -
1 stop6h 45m
Mon 10/121:30 pm -
2 stops8h 40m
Deal found 9/1![Southwest logo]()
$403
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 am -
2 stops10h 10m
Sun 1/176:00 am -
1 stop6h 13m
Deal found 9/2![Delta logo]()
$424
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:35 pm -
1 stop4h 55m
Sun 10/116:15 am -
1 stop7h 20m
Deal found 8/30![Southwest logo]()
$418
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:25 pm -
2 stops10h 14m
Sun 10/46:00 am -
1 stop7h 49m
Deal found 8/31![Delta logo]()
$424
Last-minute flights from Des Moines to HoustonDiscover last-minute flight deals from Des Moines to Houston. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Houston. Data last updated September 4, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm -
1 stop20h 15m
Thu 9/1010:38 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$264
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm -
1 stop20h 15m
Fri 9/1110:30 am -
1 stop9h 03m
Deal found 9/1![Frontier logo]()
$297
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:30 pm -
1 stop25h 25m
Sun 9/1310:38 pm -
1 stop20h 55m
Deal found 8/30![Frontier logo]()
$290
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop28h 13m
Sun 9/2010:38 pm -
1 stop20h 55m
Deal found 8/31![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:30 pm -
1 stop13h 05m
Sun 9/2710:38 pm -
1 stop20h 55m
Deal found 9/2![Frontier logo]()
$232
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:29 am -
1 stop13h 14m
Fri 10/26:25 am -
1 stop13h 08m
Deal found 8/30![Frontier logo]()
$241
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:29 am -
1 stop13h 14m
Sun 10/410:38 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$266
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
1 stop28h 15m
Mon 10/126:24 am -
1 stop13h 06m
Deal found 9/1![Frontier logo]()
$262
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:10 pm -
1 stop6h 45m
Thu 10/225:10 pm -
1 stop5h 00m
Deal found 9/2![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:35 pm -
1 stop4h 55m
Fri 10/305:25 pm -
1 stop4h 55m
Deal found 8/31![Southwest logo]()
$314
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop13h 22m
Sun 11/110:40 pm -
1 stop20h 55m
Deal found 9/1![Frontier logo]()
$263
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop28h 12m
Thu 11/510:40 pm -
1 stop20h 55m
Deal found 8/31![Frontier logo]()
$269
One-way flights from Des Moines to HoustonSearch for one-way flight options from Des Moines to Houston. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Des Moines to Houston. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Super.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:30 pm -
1 stop28h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$115
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:29 am -
1 stop22h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Frontier logo]()
$132
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
1 stop13h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
2 stops46h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/30![Multiple Airlines logo]()
$153
This Expedia deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am -
1 stop22h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$156
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:14 am -
1 stop7h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$160
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:57 pm -
1 stop6h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am -
2 stops23h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:57 pm -
2 stops26h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$166
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:12 pm -
1 stop4h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![American Airlines logo]()
$177
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:20 pm -
1 stop5h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/30![Southwest logo]()
$180
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:40 am -
2 stops8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/30![Southwest logo]()
$185
Find flight deals from Des Moines to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 4, 2026.
Round-trip from | $232 (CheapOair) |
|---|---|
One-way from | $115 (Super.com) |
Popular in | March |
Cheapest in | July |
Average price | $359 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Des Moines to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Fri 9/25
8:30 pm-12:43 am
1 stop28h 13m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$115
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Sun 10/11
8:43 am-7:19 am
2 stops46h 36m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Thu 9/24
6:55 pm-12:30 am
1 stop5h 35m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Sat 9/26
5:57 pm-11:59 pm
1 stop6h 02m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Mon 9/14
8:30 pm-12:43 am
1 stop28h 13m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Thu 10/1
8:10 am-7:17 am
2 stops23h 07m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Des MoinesHouston
DSM Des Moines - HOU Houston Hobby
DSMHOU
Des Moines
Thu 12/17
1:50 pm-10:50 pm
1 stop9h 00m
Houston Hobby
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$180
Des MoinesHouston
DSM Des Moines - HOU Houston Hobby
DSMHOU
Des Moines
Sun 11/1
1:50 pm-10:50 pm
1 stop9h 00m
Houston Hobby
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$180
Quickest round-trip
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Sat 9/26
6:00 am-8:24 am
Nonstop2h 24m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
Des MoinesHouston
DSM Des Moines - IAH Houston George Bush Intcntl
DSMIAH
Des Moines
Thu 10/1
6:00 am-8:24 am
Nonstop2h 24m
Houston George Bush Intcntl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Des Moines with our price prediction graph.
DSM-HO1
DSM-IAH
DSM-HOU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Houston
DSM-HO1
DSM-IAH
DSM-HOU
What is the cheapest month to book a flight from Des Moines to Houston?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Houston (average of $277). Flying from Des Moines to Houston in March is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to HOU?
Find hourly flight availability from Des Moines to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 4, 2026.
When flying from Des Moines to Houston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Des Moines to Houston?
Airfare is below average for this route at the moment.
Des Moines to Houston flights typically cost between $320 and $407 in September.The cheapest round-trip price found within the last 5 days was $232 on Frontier (Sep 25-Sep 27).
How far ahead should I book a flight from Des Moines to Houston?
To ensure you get the cheapest price possible for a flight from Des Moines to Houston, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated September 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Houston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Houston
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Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Houston by cabin class
Find flights from Des Moines to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Houston flights
Browse other Des Moines and Houston flight options. Last updated on September 4, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Houston
Discover the top 5 airlines that operate flights from Des Moines to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$130 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$156 | Average$378 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$335 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$334 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$230 | Average$335 | FlexibilityNo cancel fee | On-time71% |