$153+ Cheap flights from Des Moines to Harlingen (DSM - HRL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — HRL
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Harlingen with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Harlingen
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Best
Last-minute
One-way
Cheapest flights from Des Moines to HarlingenExplore the most affordable flight options available from Des Moines to Harlingen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Des Moines to Harlingen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am -
1 stop7h 09m
Mon 9/215:18 pm -
1 stop5h 12m
Deal found 9/2![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:00 am -
1 stop8h 01m
Wed 11/185:05 am -
2 stops11h 02m
Deal found 9/2![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:14 pm -
1 stop6h 34m
Fri 9/185:28 pm -
1 stop5h 44m
Deal found 9/3![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop4h 46m
Wed 11/115:25 pm -
1 stop5h 05m
Deal found 9/6![United Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 23m
Fri 10/95:18 pm -
1 stop4h 57m
Deal found 9/2![United Airlines logo]()
$496
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm -
2 stops7h 10m
Sat 9/127:00 am -
2 stops13h 50m
Deal found 9/5![Southwest logo]()
$511
Best flights from Des Moines to HarlingenDiscover carefully curated flight deals from Des Moines to Harlingen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Des Moines to Harlingen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/203:31 pm -
1 stop7h 23m
Sun 1/242:47 pm -
1 stop7h 23m
Deal found 9/5![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/298:00 am -
1 stop7h 34m
Mon 2/15:16 pm -
1 stop5h 14m
Deal found 9/7![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:55 am -
2 stops13h 40m
Sat 1/167:30 am -
2 stops11h 50m
Deal found 9/5![Southwest logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am -
1 stop7h 09m
Mon 9/215:18 pm -
1 stop5h 12m
Deal found 9/2![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:00 am -
1 stop8h 01m
Wed 11/185:05 am -
2 stops11h 02m
Deal found 9/2![United Airlines logo]()
$424
Last-minute flights from Des Moines to HarlingenDiscover last-minute flight deals from Des Moines to Harlingen. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Harlingen. Data last updated September 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm -
2 stops7h 10m
Sat 9/127:00 am -
2 stops13h 50m
Deal found 9/5![Southwest logo]()
$511
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:15 am -
2 stops9h 30m
Thu 9/106:20 am -
2 stops7h 25m
Deal found 9/4![Southwest logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:22 pm -
1 stop4h 32m
Sat 9/1210:45 am -
1 stop7h 07m
Deal found 9/5![American Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:13 am -
2 stops10h 26m
Wed 9/165:05 am -
2 stops7h 27m
Deal found 9/3![United Airlines logo]()
$552
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:02 pm -
1 stop6h 50m
Wed 9/165:18 pm -
1 stop5h 12m
Deal found 9/3![United Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:14 pm -
1 stop6h 34m
Fri 9/185:28 pm -
1 stop5h 44m
Deal found 9/3![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am -
1 stop7h 09m
Mon 9/215:18 pm -
1 stop5h 12m
Deal found 9/2![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 23m
Fri 10/95:18 pm -
1 stop4h 57m
Deal found 9/2![United Airlines logo]()
$496
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:20 am -
2 stops11h 30m
Thu 10/225:30 am -
2 stops7h 50m
Deal found 9/4![Southwest logo]()
$524
One-way flights from Des Moines to HarlingenSearch for one-way flight options from Des Moines to Harlingen. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Des Moines to Harlingen. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
2 stops10h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Southwest logo]()
$153
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$182
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops12h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/191:55 pm -
2 stops9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$384
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:05 am -
1 stop4h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:38 pm -
1 stop22h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$469
Find flight deals from Des Moines to Harlingen
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Harlingen (HRL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $343 (American Airlines) |
One-way from | $153 (Southwest) |
Popular in | July |
Cheapest in | February |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Harlingen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Des Moines to Harlingen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Wed 11/4
7:00 am-5:20 pm
2 stops10h 20m
Harlingen Valley Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
Quickest round-trip
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Wed 11/4
8:00 am-4:01 pm
1 stop8h 01m
Harlingen Valley Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Fri 12/18
5:10 am-5:10 pm
2 stops12h 00m
Harlingen Valley Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Wed 1/20
3:31 pm-10:54 pm
1 stop7h 23m
Harlingen Valley Intl
Sun 1/24
2:47 pm-10:10 pm
1 stop7h 23m
$343
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Fri 1/29
8:00 am-3:34 pm
1 stop7h 34m
Harlingen Valley Intl
Mon 2/1
5:16 pm-10:30 pm
1 stop5h 14m
$363
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Sat 12/19
1:55 pm-11:40 pm
2 stops9h 45m
Harlingen Valley Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$384
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Fri 1/8
6:55 am-8:35 pm
2 stops13h 40m
Harlingen Valley Intl
Sat 1/16
7:30 am-7:20 pm
2 stops11h 50m
$409
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Thu 9/17
6:15 am-1:24 pm
1 stop7h 09m
Harlingen Valley Intl
Mon 9/21
5:18 pm-10:30 pm
1 stop5h 12m
$416
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Tue 11/17
8:00 am-4:01 pm
1 stop8h 01m
Harlingen Valley Intl
Wed 11/18
5:05 am-4:07 pm
2 stops11h 02m
$424
Des MoinesHarlingen
DSM Des Moines - HRL Harlingen Valley Intl
DSMHRL
Des Moines
Sat 12/19
7:38 pm-5:51 pm
1 stop22h 13m
Harlingen Valley Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$469
Sorted by cheapest first
Compare providers for flights from Des Moines to Harlingen
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Harlingen in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Harlingen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Harlingen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Harlingen flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Harlingen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Harlingen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Harlingen
Have a flexible travel schedule? Discover the best time to fly to Harlingen from Des Moines with our price prediction graph.
DSM-HRL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Harlingen
Get insights into the airlines that provide service to Harlingen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harlingen. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Harlingen to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreIsaac,May 2024
SHV - IAH
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreIsaac,May 2024
SHV - IAH
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreIsaac,May 2024
SHV - IAH
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Harlingen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Harlingen by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Harlingen
Explore flights to Harlingen departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Des Moines and Harlingen flights
Browse other Des Moines and Harlingen flight options. Last updated on September 7, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Harlingen
Discover the top 2 airlines that operate flights from Des Moines to Harlingen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$325 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$259 | Average$389 | FlexibilityNo cancel fee | On-time69% |