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Guayaquil

$199+ Cheap flights from Des Moines (DSM) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GYE
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Des Moines to Guayaquil

Cheapest flights from Des Moines to Guayaquil
Explore the most affordable flight options available from Des Moines to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:32 pm
DSM
-
GYE
1 stop31h 32m
Multiple Airlines
Sun 3/1511:59 pm
GYE
-
DSM
2 stops18h 28m
Multiple Airlines
Deal found 1/25$552
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:52 am
DSM
-
GYE
2 stops11h 54m
United Airlines
Sun 3/152:35 pm
GYE
-
DSM
2 stops32h 09m
United Airlines
Deal found 1/25$775
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/88:10 am
DSM
-
GYE
2 stops35h 36m
United Airlines
Wed 2/112:35 pm
GYE
-
DSM
2 stops32h 45m
United Airlines
Deal found 1/25$832
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:15 am
DSM
-
GYE
2 stops34h 18m
United Airlines
Wed 3/1812:20 pm
GYE
-
DSM
3 stops27h 47m
United Airlines
Deal found 1/25$852
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:00 am
DSM
-
GYE
2 stops38h 04m
Multiple Airlines
Wed 3/1811:59 pm
GYE
-
DSM
1 stop23h 29m
Multiple Airlines
Deal found 1/25$887
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:35 am
DSM
-
GYE
1 stop15h 06m
American Airlines
Sun 3/156:12 am
GYE
-
DSM
1 stop17h 44m
American Airlines
Deal found 1/25$1,012
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:52 pm
DSM
-
GYE
2 stops23h 38m
American Airlines
Fri 3/202:30 pm
GYE
-
DSM
2 stops18h 31m
American Airlines
Deal found 1/27$1,469

Find flight deals from Des Moines to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$552
(Kiwi.com)

One-way from

$199
(Kiwi.com)
Provider with most accurate pricing for Des Moines-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Des Moines to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Des Moines to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Des Moines to Guayaquil that are best for you.

Fly from

Des Moines

Fly to

Guayaquil

Route

Depart

Return

Price

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 2/15

3:32 pm-12:04 am

1 stop31h 32m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

11:59 pm-6:27 pm

2 stops18h 28m

$552

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 2/15

7:52 am-8:46 pm

2 stops11h 54m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

2:35 pm-10:44 pm

2 stops32h 09m

$775

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 2/8

8:10 am-5:35 pm

2 stops32h 25m

Guayaquil Jose Joaquin de Olmedo

Wed 2/11

2:35 pm-10:20 pm

2 stops32h 45m

$832

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 3/11

7:15 am-5:33 pm

2 stops34h 18m

Guayaquil Jose Joaquin de Olmedo

Wed 3/18

12:20 pm-4:07 pm

3 stops27h 47m

$852

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 3/11

9:00 am-11:04 pm

2 stops38h 04m

Guayaquil Jose Joaquin de Olmedo

Wed 3/18

11:59 pm-11:28 pm

1 stop23h 29m

$887

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 2/15

6:35 am-10:41 pm

1 stop15h 06m

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

6:12 am-11:56 pm

1 stop17h 44m

$1,012

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 3/13

1:52 pm-1:30 pm

2 stops23h 38m

Guayaquil Jose Joaquin de Olmedo

Fri 3/20

2:30 pm-9:01 am

2 stops18h 31m

$1,469

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 2/15

9:00 am-12:04 am

2 stops38h 04m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Compare providers for flights from Des Moines to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guayaquil in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Guayaquil?

    Departing from Des Moines to Guayaquil will take you 11h 54m. The distance from Des Moines to Guayaquil is about 3138 mi.

  • Can I find deals for flights from Des Moines to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guayaquil.

  • Can I find deals for business class flights from Des Moines to Guayaquil?

    Yes. Cheapflights offers flight deals from Des Moines to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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