HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$185+ Cheap flights from Santa Ana, CA to Greenville (SNA - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Greenville

Cheapest flights from Santa Ana to Greenville
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:45 am
SNA
-
GSP
1 stop8h 14m
Delta
Tue 8/255:20 pm
GSP
-
SNA
1 stop7h 36m
Delta
Deal found 7/27$369
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:45 am
SNA
-
GSP
1 stop8h 14m
Delta
Fri 9/116:25 pm
GSP
-
SNA
1 stop6h 39m
Delta
Deal found 7/29$371
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:59 pm
SNA
-
GSP
2 stops10h 37m
United Airlines
Thu 8/275:43 pm
GSP
-
SNA
1 stop7h 42m
United Airlines
Deal found 7/28$374
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:45 am
SNA
-
GSP
1 stop8h 14m
Delta
Wed 8/265:20 pm
GSP
-
SNA
1 stop7h 36m
Delta
Deal found 7/27$402
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:13 am
SNA
-
GSP
2 stops11h 50m
United Airlines
Fri 9/114:19 pm
GSP
-
SNA
1 stop7h 25m
United Airlines
Deal found 7/29$407
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:30 am
SNA
-
GSP
2 stops10h 25m
Southwest
Thu 8/271:05 pm
GSP
-
SNA
2 stops8h 55m
Southwest
Deal found 7/28$412
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:45 am
SNA
-
GSP
2 stops9h 10m
Southwest
Fri 9/111:05 pm
GSP
-
SNA
2 stops8h 55m
Southwest
Deal found 7/29$433
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 am
SNA
-
GSP
1 stop9h 00m
Delta
Wed 8/265:20 pm
GSP
-
SNA
1 stop7h 36m
Delta
Deal found 7/27$435
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:35 am
SNA
-
GSP
2 stops9h 15m
American Airlines
Thu 8/201:37 pm
GSP
-
SNA
1 stop7h 33m
American Airlines
Deal found 7/26$461
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:30 am
SNA
-
GSP
2 stops10h 05m
Southwest
Fri 10/91:05 pm
GSP
-
SNA
2 stops9h 55m
Southwest
Deal found 7/28$464
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:00 am
SNA
-
GSP
2 stops9h 35m
Southwest
Thu 8/201:05 pm
GSP
-
SNA
2 stops8h 55m
Southwest
Deal found 7/26$467
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:45 am
SNA
-
GSP
1 stop6h 49m
American Airlines
Fri 10/95:25 pm
GSP
-
SNA
1 stop8h 04m
American Airlines
Deal found 7/28$473

Find flight deals from Santa Ana to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(United Airlines)

One-way from

$185
(Delta)

Popular in

December

Cheapest in

March

Average price

$586
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Greenville flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Greenville
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sat 10/3

7:30 am-8:35 pm

2 stops10h 05m

Greenville

Fri 10/9

1:05 pm-8:00 pm

2 stops9h 55m

$464
Quickest round-trip

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

6:45 am-5:02 pm

1 stop7h 17m

Greenville

Sat 8/29

2:28 pm-6:51 pm

1 stop7h 23m

$479

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

10:20 am-9:07 pm

1 stop7h 47m

Greenville

Wed 9/2

11:25 am-5:24 pm

1 stop8h 59m

$479

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

9:05 pm-10:37 am

1 stop10h 32m

Greenville

Sat 8/29

11:25 am-7:57 pm

1 stop11h 32m

$479

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Fri 9/4

11:45 am-10:59 pm

1 stop8h 14m

Greenville

Mon 9/7

3:25 pm-9:56 pm

1 stop9h 31m

$487
Cheapest one-way
Quickest one-way

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 9/16

2:00 pm-10:55 pm

1 stop5h 55m

$185

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 9/29

12:14 pm-10:11 pm

1 stop6h 57m

$185

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 9/29

11:38 am-10:55 pm

1 stop8h 17m

$185

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Thu 9/10

2:00 pm-11:00 pm

1 stop6h 00m

$185

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 9/29

6:45 am-7:30 pm

2 stops9h 45m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Santa Ana to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Greenville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Greenville

What is the cheapest month to book a flight from Santa Ana, California to Greenville?

Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $389). Flying from Santa Ana, California to Greenville in December is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 30, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,487 reviews

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Delta
7.8
Good
8,487 reviews
Delta
7.8
Good
8,487 reviews

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
United Airlines
7.4
Good
10,046 reviews
Delta
7.8
Good
8,487 reviews

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
American Airlines
7.1
Good
11,841 reviews
Delta
7.8
Good
8,487 reviews

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Greenville?

    A quick flight from Santa Ana, California to Greenville can take about 7h 17m. Southwest provides one of the quickest options available for as low as $479. The distance from Santa Ana, California to Greenville is about 2025 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Santa Ana, California to Greenville round-trip?

    According to our current data, American Airlines ($303), Delta ($332), and United Airlines ($336) offers the cheapest pricing from Santa Ana, California to Greenville. American Airlines is priced at 43% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Ana to Greenville that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Greenville.

  • Can I find deals for business class flights from Santa Ana to Greenville?

    Yes. Cheapflights offers flight deals from Santa Ana to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Greenville?

    Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $389). Flying from Santa Ana, California to Greenville in December is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Charlotte flights
San Francisco to Charlotte flights
Ontario to Charlotte flights
San Diego to Charlotte flights
San Francisco to Charleston flights
Los Angeles to Charleston flights
Los Angeles to Savannah flights
Santa Ana to Charlotte flights
Las Vegas to Charlotte flights
San Francisco to Savannah flights
Los Angeles to Myrtle Beach flights
Burbank to Charlotte flights
Los Angeles to Columbia flights
San Francisco to Greenville flights
Ontario to Savannah flights
San Diego to Columbia flights
Sacramento to Charlotte flights
San Jose to Charlotte flights
San Diego to Charleston flights
San Diego to Savannah flights
Los Angeles to Greenville flights
San Francisco to Myrtle Beach flights
Las Vegas to Charleston flights
Fresno to Charlotte flights
Ontario to Greenville flights
Los Angeles to Hilton Head Island flights
Ontario to Columbia flights
Long Beach to Charlotte flights
San Diego to Greenville flights
Oakland to Charlotte flights
San Diego to Myrtle Beach flights
Las Vegas to Columbia flights
Fresno to Myrtle Beach flights
Las Vegas to Greenville flights
Sacramento to Charleston flights
Burbank to Savannah flights
Ontario to Augusta flights
Ontario to Myrtle Beach flights
Fresno to Charleston flights
San Jose to Savannah flights
Sacramento to Columbia flights
Las Vegas to Myrtle Beach flights
San Jose to Greenville flights
Los Angeles to Augusta flights
Las Vegas to Savannah flights
Sacramento to Savannah flights

Top 3 airlines flying from Santa Ana to Greenville

Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$303Average$586FlexibilityNo cancel feeOn-time71%
DeltaCheapest$332Average$462FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$336Average$505FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.