HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$149+ Cheap flights from Santa Ana to Greenville (SNA - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$346
(American Airlines)

One-way from

$149
(Delta)

Popular in

June

Cheapest in

August

Average price

$721
From Santa Ana J. Wayne/Orange Cnty to Greenville
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Santa Ana to Greenville

Cheapest flights from Santa Ana to Greenville
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/1411:28 amSNA - GSP
1 stop7h 49mAmerican Airlines
mar. 8/197:33 amGSP - SNA
1 stop9h 46mAmerican Airlines
Deal found 6/10$346
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/147:20 amSNA - GSP
2 stops10h 40mSouthwest
mar. 8/1910:25 amGSP - SNA
2 stops11h 05mSouthwest
Deal found 6/10$347
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/159:20 pmSNA - GSP
1 stop9h 01mDelta
dom. 8/175:30 amGSP - SNA
1 stop8h 23mDelta
Deal found 6/10$371
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/147:05 pmSNA - GSP
2 stops11h 47mUnited Airlines
dom. 8/174:25 pmGSP - SNA
1 stop7h 42mUnited Airlines
Deal found 6/10$439
This Alaska Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/167:00 amSNA - GSP
2 stops11h 50mAlaska Airlines
dom. 10/197:55 amGSP - SNA
2 stops13h 30mAlaska Airlines
Deal found 6/11$687

Cheapflights Fare Finder

Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.

Fly from

Santa Ana

Fly to

Greenville

Route

Depart

Return

Price

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 8/14

11:28 am-10:17 pm

1 stop7h 49m

Greenville

mar. 8/19

7:33 am-2:19 pm

1 stop9h 46m

$346

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 8/14

7:20 am-9:00 pm

2 stops10h 40m

Greenville

mar. 8/19

10:25 am-6:30 pm

2 stops11h 05m

$347

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 8/15

9:20 pm-9:21 am

1 stop9h 01m

Greenville

dom. 8/17

5:30 am-10:53 am

1 stop8h 23m

$371

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 8/14

7:05 pm-9:52 am

2 stops11h 47m

Greenville

dom. 8/17

4:25 pm-9:07 pm

1 stop7h 42m

$439

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 10/16

7:00 am-9:50 pm

2 stops11h 50m

Greenville

dom. 10/19

7:55 am-6:25 pm

2 stops13h 30m

$687

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

mié. 8/20

12:03 pm-10:24 pm

1 stop7h 21m

$149

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

sáb. 9/13

6:45 am-4:57 pm

1 stop7h 12m

$158

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

mié. 8/20

6:35 pm-9:49 am

2 stops12h 14m

$204

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

dom. 8/10

6:25 pm-9:55 am

2 stops12h 30m

$219

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 10/16

7:00 am-9:50 pm

2 stops11h 50m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 12 results
1
2

Best time to book a flight from Santa Ana to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Greenville

What is the cheapest month to book a flight from Santa Ana to Greenville?

Currently, January is the cheapest month in which you can book a flight from Santa Ana to Greenville (average of $329). Flying from Santa Ana to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to GSP?

Find hourly flight availability from Santa Ana to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Santa Ana to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 2% versus a flight in the afternoon.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated junio 12, 2025.
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
178 reviews
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Alaska Airlines
8.0
Very good
10,000 reviews
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Southwest
8.0
Very good
4,287 reviews
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,950 reviews
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,790 reviews
Breeze Airways
8.1
Very good
178 reviews

Boarding

8.3

Food

6.7

Crew

8.8

Comfort

8.2

Overall

8.1

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santa Ana to Greenville round-trip?

    American Airlines, at $346, was found to be the cheapest airline from Santa Ana to Greenville.Alternate airlines to your destination round-trip include Southwest and Delta. These flights start at 27% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Santa Ana to Greenville one-way?

    $149 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $158 and $204, respectively.

  • Can I find deals for flights from Santa Ana to Greenville that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Greenville.

  • Can I find deals for business class flights from Santa Ana to Greenville?

    Yes. Cheapflights offers flight deals from Santa Ana to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Santa Ana to Greenville (average of $329). Flying from Santa Ana to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
San Francisco to Charlotte flights
Los Angeles to Charlotte flights
Ontario to Charlotte flights
San Francisco to Charleston flights
Sacramento to Charlotte flights
Burbank to Charlotte flights
Los Angeles to Charleston flights
Santa Ana to Charlotte flights
San Diego to Charlotte flights
Las Vegas to Charlotte flights
Los Angeles to Savannah flights
San Francisco to Savannah flights
Oakland to Charlotte flights
San Francisco to Myrtle Beach flights
San Francisco to Greenville flights
San Jose to Charlotte flights
Los Angeles to Columbia flights
Ontario to Greenville flights
Ontario to Charleston flights
Los Angeles to Greenville flights
Sacramento to Charleston flights
Los Angeles to Myrtle Beach flights
Ontario to Savannah flights
San Diego to Savannah flights
Los Angeles to Hilton Head Island flights
Santa Ana to Charleston flights
Palm Springs to Savannah flights
Las Vegas to Savannah flights
Reno to Charlotte flights
Las Vegas to Charleston flights
Las Vegas to Myrtle Beach flights
San Diego to Charleston flights
San Diego to Myrtle Beach flights
Fresno to Charlotte flights
Ontario to Myrtle Beach flights
Las Vegas to Augusta flights
San Francisco to Hilton Head Island flights
Sacramento to Columbia flights
San Jose to Myrtle Beach flights
Sacramento to Myrtle Beach flights
San Diego to Columbia flights
Sacramento to Greenville flights
San Francisco to Columbia flights
Palm Springs to Charlotte flights
Santa Ana to Myrtle Beach flights
Burbank to Myrtle Beach flights
Fresno to Savannah flights
Las Vegas to Columbia flights
San Diego to Greenville flights
Ontario to Columbia flights

Top 3 airlines flying from Santa Ana to Greenville

Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$351Average$449FlexibilityNo cancel feeOn-time71%
DeltaCheapest$356Average$407FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$361Average$516FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.