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Greenville

$84+ Cheap flights from Ohio to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — GSP
Jan 26 — Feb 21
Mon 1/26
Mon 2/2
1 adult, Economy
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Cheap flight deals from Ohio to Greenville

Cheapest flights from Ohio to Greenville
Explore the most affordable flight options available from Ohio to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:46 pmCAK - GSP
1 stop4h 12mAmerican Airlines
Tue 1/65:40 pmGSP - CAK
1 stop3h 38mAmerican Airlines
Deal found 12/25$309
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:39 pmCMH - GSP
1 stop7h 17mUnited Airlines
Wed 12/315:36 pmGSP - CMH
1 stop4h 40mUnited Airlines
Deal found 12/24$420
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:40 amCLE - GSP
1 stop15h 00mMultiple Airlines
Wed 12/314:45 pmGSP - CLE
1 stop17h 52mMultiple Airlines
Deal found 12/25$433
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:58 pmCLE - GSP
1 stop11h 55mMultiple Airlines
Wed 12/314:45 pmGSP - CLE
1 stop22h 01mMultiple Airlines
Deal found 12/26$488
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:10 amCLE - GSP
1 stop7h 45mMultiple Airlines
Sun 1/45:17 pmGSP - CLE
2 stops41h 20mMultiple Airlines
Deal found 12/26$489
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:53 pmPIT - GSP
2 stops29h 10mMultiple Airlines
Thu 1/19:33 amGSP - PIT
Nonstop1h 36mMultiple Airlines
Deal found 12/27$489
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:03 pmCLE - GSP
1 stop5h 32mDelta
Sat 1/36:23 pmGSP - CLE
1 stop4h 08mDelta
Deal found 12/25$528
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amCLE - GSP
2 stops6h 19mAmerican Airlines
Sat 1/36:20 pmGSP - CLE
1 stop3h 35mAmerican Airlines
Deal found 12/27$533
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:45 pmCMH - GSP
1 stop4h 05mSouthwest
Wed 1/76:15 pmGSP - CMH
1 stop4h 00mSouthwest
Deal found 12/26$555
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:45 amDTW - GSP
1 stop8h 10mMultiple Airlines
Sun 1/411:33 amGSP - DTW
2 stops44h 34mMultiple Airlines
Deal found 12/25$565
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 amCLE - GSP
2 stops9h 20mSouthwest
Sun 1/410:40 amGSP - CLE
2 stops11h 20mSouthwest
Deal found 12/26$574
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2712:36 pmPIT - GSP
2 stops50h 04mMultiple Airlines
Tue 12/309:33 amGSP - PIT
Nonstop1h 36mMultiple Airlines
Deal found 12/25$576

Find flight deals from Ohio to Greenville

Keep the following information in mind while searching for Ohio to Greenville flight deals. Data was last updated December 27, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$176
(Kiwi.com)

One-way from

$84
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$349
Provider with most accurate pricing for Cleveland Hopkins Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Greenville flights.
Search Deals
From Ohio to Greenville
Search Deals
One-way flight from Ohio to Greenville
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Ohio to Greenville that are best for you.

Fly from

Ohio

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 1/15

3:12 pm-8:58 am

1 stop17h 46m

Greenville

Mon 1/19

4:39 pm-10:54 am

1 stop18h 15m

$177

PittsburghGreenville

PIT - GSP

PITGSP

Pittsburgh

Fri 1/23

5:32 am-3:59 pm

1 stop10h 27m

Greenville

Fri 1/30

9:48 am-9:40 am

1 stop23h 52m

$195

CincinnatiGreenville

CVG - GSP

CVGGSP

Cincinnati Cinci./N. Kentucky

Thu 2/19

6:05 am-1:12 pm

1 stop7h 07m

Greenville

Mon 2/23

8:18 pm-9:25 pm

1 stop25h 07m

$199

CincinnatiGreenville

CVG - GSP

CVGGSP

Cincinnati Cinci./N. Kentucky

Sun 1/25

5:47 pm-8:07 pm

1 stop26h 20m

Greenville

Sun 2/1

5:45 pm-2:57 pm

1 stop21h 12m

$211

CincinnatiGreenville

CVG - GSP

CVGGSP

Cincinnati Cinci./N. Kentucky

Fri 2/6

7:00 am-7:38 pm

1 stop12h 38m

Greenville

Sun 2/8

2:12 pm-11:29 pm

1 stop9h 17m

$216

CincinnatiGreenville

CVG - GSP

CVGGSP

Cincinnati Cinci./N. Kentucky

Thu 1/8

1:35 pm-8:58 am

1 stop19h 23m

Greenville

Mon 1/12

4:07 pm-12:42 am

1 stop8h 35m

$222

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 2/4

9:10 pm-1:12 pm

1 stop16h 02m

Greenville

Thu 2/26

2:12 pm-10:44 am

1 stop20h 32m

$224

AkronGreenville

CAK - GSP

CAKGSP

Akron/Canton

Thu 1/22

11:44 am-8:58 am

1 stop21h 14m

Greenville

Thu 1/29

9:47 pm-10:40 pm

2 stops24h 53m

$225

PittsburghGreenville

PIT - GSP

PITGSP

Pittsburgh

Sat 1/24

7:14 pm-11:51 pm

1 stop4h 37m

Greenville

Sat 1/31

12:35 pm-11:59 pm

1 stop11h 24m

$247

DaytonGreenville

DAY - GSP

DAYGSP

Dayton

Sat 1/17

2:52 pm-7:29 pm

1 stop4h 37m

Greenville

Tue 1/20

6:35 am-1:23 pm

1 stop6h 48m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Greenville

What is the cheapest month to book a flight from Ohio to Greenville?

Currently, July is the cheapest month in which you can book a flight from Ohio to Greenville (average of $87). Flying from Ohio to Greenville in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to GSP?

Find hourly flight availability from Ohio to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 27, 2025.

One of the essential ways to save on airfare from Ohio to Greenville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 19% on airfare.

What is the cheapest day to fly from Ohio to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Ohio to Greenville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to Greenville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Ohio?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Ohio to Greenville.

  • How long is the flight from Ohio to Greenville?

    A quick flight from Ohio to Greenville can take about 4h 37m. American Airlines provides one of the quickest options available for as low as $247. There are 401 mi between Ohio and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Ohio to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $77. Southwest flights start at $92 while deals on American Airlines start at $98 one-way.

  • What are the most popular routes from Ohio to Greenville?

    While some choose either Dayton - Greenville or Pittsburgh - Greenville, Detroit Metropolitan Wayne County - Greenville is the most popular route from Ohio to Greenville.

  • Can I find deals for flights from Ohio to Greenville that include hotel bookings?

    Yes. In addition to deals on Ohio to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Greenville.

  • Can I find deals for business class flights from Ohio to Greenville?

    Yes. Cheapflights offers flight deals from Ohio to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Greenville?

    Currently, July is the cheapest month in which you can book a flight from Ohio to Greenville (average of $87). Flying from Ohio to Greenville in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 4 airlines flying from Ohio to Greenville

Discover the top 4 airlines that operate flights from Ohio to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$164Average$327FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$361FlexibilityNo cancel feeOn-time63%
DeltaCheapest$196Average$322FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$217Average$324FlexibilityNo cancel feeOn-time69%

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