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Greenville

$96+ Cheap flights from Ohio to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — GSP
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from Ohio to Greenville

Cheapest flights from Ohio to Greenville
Explore the most affordable flight options available from Ohio to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:50 am
PIT
-
GSP
1 stop4h 37m
Multiple Airlines
Mon 3/234:28 pm
GSP
-
PIT
1 stop28h 44m
Multiple Airlines
Deal found 1/19$221
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/265:15 am
DTW
-
GSP
1 stop10h 44m
Multiple Airlines
Mon 2/29:48 am
GSP
-
DTW
2 stops27h 42m
Multiple Airlines
Deal found 1/19$228
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:45 am
CMH
-
GSP
1 stop13h 53m
Multiple Airlines
Mon 2/236:22 pm
GSP
-
CMH
1 stop16h 22m
Multiple Airlines
Deal found 1/19$234
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:02 am
DTW
-
GSP
1 stop7h 25m
Multiple Airlines
Mon 2/236:22 pm
GSP
-
DTW
1 stop14h 53m
Multiple Airlines
Deal found 1/19$238
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:15 pm
PIT
-
GSP
1 stop14h 43m
Multiple Airlines
Thu 2/123:37 pm
GSP
-
PIT
1 stop5h 39m
Multiple Airlines
Deal found 1/19$242
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:37 pm
DAY
-
GSP
1 stop4h 37m
American Airlines
Tue 2/1711:29 am
GSP
-
DAY
1 stop5h 36m
American Airlines
Deal found 1/19$249
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/72:02 pm
CAK
-
GSP
1 stop6h 40m
United Airlines
Tue 2/176:30 am
GSP
-
CAK
1 stop6h 44m
United Airlines
Deal found 1/19$254
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/178:00 am
CMH
-
GSP
1 stop6h 02m
Delta
Tue 2/246:49 am
GSP
-
CMH
1 stop4h 55m
Delta
Deal found 1/19$255
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:05 am
CLE
-
GSP
1 stop6h 57m
Delta
Tue 3/35:18 pm
GSP
-
CLE
1 stop4h 40m
Delta
Deal found 1/19$255
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:56 am
PIT
-
GSP
1 stop7h 56m
United Airlines
Wed 2/186:30 am
GSP
-
PIT
1 stop6h 39m
United Airlines
Deal found 1/18$255
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/16:00 am
PIT
-
GSP
1 stop26h 58m
Multiple Airlines
Thu 2/55:45 pm
GSP
-
PIT
1 stop15h 55m
Multiple Airlines
Deal found 1/19$257
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/32:37 pm
DAY
-
GSP
1 stop4h 10m
Delta
Sat 2/76:50 am
GSP
-
DAY
1 stop4h 00m
Delta
Deal found 1/18$259

Find flight deals from Ohio to Greenville

Keep the following information in mind while searching for Ohio to Greenville flight deals. Data was last updated January 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$184
(Kiwi.com)

One-way from

$96
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$326
Provider with most accurate pricing for Cleveland Hopkins Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Greenville flights.
Search Deals
From Ohio to Greenville
Search Deals
One-way flight from Ohio to Greenville
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Ohio to Greenville that are best for you.

Fly from

Ohio

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Mon 1/26

5:15 am-3:59 pm

1 stop10h 44m

Greenville

Mon 2/2

4:39 pm-10:54 am

1 stop18h 15m

$229

DaytonGreenville

DAY - GSP

DAYGSP

Dayton

Fri 2/13

5:37 pm-10:14 pm

1 stop4h 37m

Greenville

Tue 2/17

7:29 am-12:11 pm

1 stop4h 42m

$249

AkronGreenville

CAK - GSP

CAKGSP

Akron/Canton

Sat 2/7

2:02 pm-8:42 pm

1 stop6h 40m

Greenville

Tue 2/17

6:30 am-1:14 pm

1 stop6h 44m

$254

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Tue 2/17

8:00 am-2:02 pm

1 stop6h 02m

Greenville

Tue 2/24

6:49 am-11:44 am

1 stop4h 55m

$255

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Tue 2/17

2:53 pm-7:24 pm

1 stop4h 31m

Greenville

Tue 2/24

10:00 am-1:57 pm

1 stop3h 57m

$255

ClevelandGreenville

CLE - GSP

CLEGSP

Cleveland Hopkins Intl

Tue 2/24

7:05 am-2:02 pm

1 stop6h 57m

Greenville

Tue 3/3

5:18 pm-9:58 pm

1 stop4h 40m

$255

PittsburghGreenville

PIT - GSP

PITGSP

Pittsburgh

Wed 2/11

8:56 am-4:52 pm

1 stop7h 56m

Greenville

Wed 2/18

6:30 am-1:09 pm

1 stop6h 39m

$255

DaytonGreenville

DAY - GSP

DAYGSP

Dayton

Tue 2/3

2:37 pm-6:47 pm

1 stop4h 10m

Greenville

Sat 2/7

6:50 am-10:50 am

1 stop4h 00m

$259

DaytonGreenville

DAY - GSP

DAYGSP

Dayton

Tue 2/3

10:24 am-7:29 pm

2 stops9h 05m

Greenville

Sat 2/7

6:35 am-1:23 pm

1 stop6h 48m

$264

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Mon 4/20

6:10 am-9:58 am

1 stop3h 48m

Greenville

Sat 4/25

7:42 pm-11:40 pm

1 stop3h 58m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Greenville

What is the cheapest month to book a flight from Ohio to Greenville?

Currently, July is the cheapest month in which you can book a flight from Ohio to Greenville (average of $87). Flying from Ohio to Greenville in January is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Ohio?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Ohio to Greenville.

  • How long is the flight from Ohio to Greenville?

    A quick flight from Ohio to Greenville can take about 4h 37m. American Airlines provides one of the quickest options available for as low as $249. There are 363 mi between Ohio and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Ohio to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $77. Southwest flights start at $92 while deals on American Airlines start at $98 one-way.

  • What are the most popular routes from Ohio to Greenville?

    While some choose either Detroit Metropolitan Wayne County - Greenville or Akron/Canton - Greenville, Cleveland Hopkins Intl - Greenville is the most popular route from Ohio to Greenville.

  • Can I find deals for flights from Ohio to Greenville that include hotel bookings?

    Yes. In addition to deals on Ohio to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Greenville.

  • Can I find deals for business class flights from Ohio to Greenville?

    Yes. Cheapflights offers flight deals from Ohio to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Greenville?

    Currently, July is the cheapest month in which you can book a flight from Ohio to Greenville (average of $87). Flying from Ohio to Greenville in January is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Ohio to Greenville

Discover the top 4 airlines that operate flights from Ohio to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$164Average$316FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$358FlexibilityNo cancel feeOn-time63%
DeltaCheapest$196Average$325FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$217Average$327FlexibilityNo cancel feeOn-time69%

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