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$139+ Cheap flights from Milwaukee to Greenville (MKE - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — GSP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Milwaukee to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$287
(Delta)

One-way from

$139
(United Airlines)

Popular in

March

Cheapest in

July

Average price

$396
From Milwaukee-Mitchell to Greenville
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One-way flight from Milwaukee-Mitchell to Greenville
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Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Milwaukee to Greenville

Cheapest flights from Milwaukee to Greenville
Explore the most affordable flight options available from Milwaukee to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:11 amMKE - GSP
1 stop4h 36mDelta
Tue 10/213:26 pmGSP - MKE
1 stop6h 40mDelta
Deal found 9/15$287
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1112:05 pmMKE - GSP
2 stops10h 41mUnited Airlines
Tue 10/145:34 pmGSP - MKE
1 stop4h 12mUnited Airlines
Deal found 9/13$292
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/253:09 pmMKE - GSP
1 stop7h 46mAmerican Airlines
Tue 12/212:06 pmGSP - MKE
1 stop4h 03mAmerican Airlines
Deal found 9/14$297
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:45 amMKE - GSP
2 stops6h 27mAmerican Airlines
Tue 10/217:11 pmGSP - MKE
1 stop5h 19mAmerican Airlines
Deal found 9/14$327
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:14 amMKE - GSP
1 stop3h 36mAmerican Airlines
Sun 11/166:40 pmGSP - MKE
1 stop6h 22mAmerican Airlines
Deal found 9/14$332
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amMKE - GSP
1 stop6h 03mAmerican Airlines
Sat 10/116:24 pmGSP - MKE
2 stops6h 32mAmerican Airlines
Deal found 9/15$337
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:50 amMKE - GSP
1 stop5h 03mUnited Airlines
Sun 10/125:34 pmGSP - MKE
1 stop4h 12mUnited Airlines
Deal found 9/15$342
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:00 amMKE - GSP
1 stop5h 46mUnited Airlines
Sun 10/126:05 amGSP - MKE
1 stop5h 40mUnited Airlines
Deal found 9/15$357
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:00 amMKE - GSP
2 stops7h 11mUnited Airlines
Tue 10/2110:05 amGSP - MKE
2 stops9h 51mUnited Airlines
Deal found 9/15$367

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Milwaukee to Greenville that are best for you.

Fly from

Milwaukee

Fly to

Greenville

Route

Depart

Return

Price

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Sat 10/11

6:00 am-1:36 pm

1 stop6h 36m

Greenville

Tue 10/14

6:05 pm-11:24 pm

1 stop6h 19m

$287

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Tue 11/25

6:14 am-10:50 am

1 stop3h 36m

Greenville

Tue 12/2

12:06 pm-3:09 pm

1 stop4h 03m

$297

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Sat 2/28

1:20 pm-8:16 pm

1 stop5h 56m

Greenville

Wed 3/4

11:55 am-5:10 pm

1 stop6h 15m

$297

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Sat 10/11

6:00 am-11:46 am

1 stop4h 46m

Greenville

Sat 10/11

5:34 pm-10:31 pm

1 stop5h 57m

$297

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Sat 1/3

5:46 pm-11:46 pm

1 stop5h 00m

Greenville

Wed 1/7

6:00 am-12:39 pm

1 stop7h 39m

$322

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Fri 1/2

7:00 am-3:01 pm

1 stop7h 01m

Greenville

Wed 1/7

3:00 pm-7:05 pm

1 stop5h 05m

$322

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 11/13

6:14 am-10:50 am

1 stop3h 36m

Greenville

Sun 11/16

6:40 pm-12:02 am

1 stop6h 22m

$332

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Fri 1/2

7:00 am-3:01 pm

1 stop7h 01m

Greenville

Thu 1/8

12:00 pm-4:17 pm

1 stop5h 17m

$332

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Tue 11/18

5:00 am-11:47 am

1 stop5h 47m

$139

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Tue 11/18

1:19 pm-10:06 pm

1 stop7h 47m

$139

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 14 results
1
2

Best time to book a flight from Milwaukee to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Greenville

What is the cheapest month to book a flight from Milwaukee to Greenville?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to Greenville (average of $321). Flying from Milwaukee to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Milwaukee to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Greenville?

    Airlines like United Airlines, American Airlines, and Delta fly from Milwaukee to Greenville in about 3h 36m. The time it takes to get you to your destination can typically vary by up to 3h. The distance from Milwaukee to Greenville is about 634 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Milwaukee to Greenville round-trip?

    Delta, at $247, was found to be the cheapest airline from Milwaukee to Greenville. An alternate airline flying to your destination would be American Airlines. You may be able to fly from Milwaukee to Greenville for 35% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Milwaukee to Greenville one-way?

    One-way options have recently been found by users for as low as $139 on United Airlines. Other airlines that offer cheap prices include Delta from $139 and American Airlines from $144 one-way.

  • Can I find deals for flights from Milwaukee to Greenville that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Greenville.

  • Can I find deals for business class flights from Milwaukee to Greenville?

    Yes. Cheapflights offers flight deals from Milwaukee to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to Greenville (average of $321). Flying from Milwaukee to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 2 airlines flying from Milwaukee to Greenville

Discover the top 2 airlines that operate flights from Milwaukee to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$247Average$382FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$261Average$432FlexibilityNo cancel feeOn-time71%

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