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Greenville

$102+ Cheap flights from Illinois to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GSP
Jul 26 — Aug 21
Sun 7/26
Sun 8/2
1 adult, Economy
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Cheap flight deals from Illinois to Greenville

Cheapest flights from Illinois to Greenville
Explore the most affordable flight options available from Illinois to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.

This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:10 am
STL
-
GSP
1 stop4h 02m
American Airlines
Tue 7/285:28 pm
GSP
-
STL
1 stop7h 30m
American Airlines
Deal found 6/23$247
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:20 pm
STL
-
GSP
1 stop6h 00m
Southwest
Tue 7/287:00 am
GSP
-
STL
2 stops7h 05m
Southwest
Deal found 6/23$252
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:50 am
STL
-
GSP
1 stop3h 25m
Southwest
Mon 8/104:40 pm
GSP
-
STL
1 stop6h 00m
Southwest
Deal found 6/22$268
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:17 pm
ORD
-
GSP
Nonstop2h 09m
United Airlines
Mon 7/205:43 pm
GSP
-
ORD
Nonstop2h 17m
United Airlines
Deal found 6/23$269
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:05 am
ORD
-
GSP
1 stop29h 36m
Multiple Airlines
Mon 7/208:13 pm
GSP
-
ORD
2 stops17h 02m
Multiple Airlines
Deal found 6/23$270
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:55 am
ORD
-
GSP
Nonstop2h 00m
United Airlines
Thu 7/306:10 am
GSP
-
ORD
Nonstop2h 20m
United Airlines
Deal found 6/23$276
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:50 pm
ORD
-
GSP
2 stops17h 07m
Multiple Airlines
Fri 7/243:31 pm
GSP
-
ORD
1 stop21h 44m
Multiple Airlines
Deal found 6/25$278
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:05 am
ORD
-
GSP
1 stop8h 34m
Multiple Airlines
Mon 8/108:45 pm
GSP
-
ORD
1 stop27h 25m
Multiple Airlines
Deal found 6/21$282
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:00 pm
STL
-
GSP
2 stops6h 55m
Southwest
Sat 10/38:00 am
GSP
-
STL
2 stops6h 00m
Southwest
Deal found 6/24$287
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:39 pm
MDW
-
GSP
1 stop4h 51m
Delta
Sun 8/96:55 am
GSP
-
MDW
1 stop5h 56m
Delta
Deal found 6/23$289
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:30 am
ORD
-
GSP
1 stop4h 27m
Delta
Tue 7/285:16 pm
GSP
-
ORD
1 stop4h 17m
Delta
Deal found 6/26$289
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:59 pm
ORD
-
GSP
Nonstop1h 59m
American Airlines
Mon 7/207:20 pm
GSP
-
ORD
Nonstop2h 31m
American Airlines
Deal found 6/26$290

Find flight deals from Illinois to Greenville

Keep the following information in mind while searching for Illinois to Greenville flight deals. Data was last updated June 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$247
(American Airlines)

One-way from

$102
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$331

Good round-trip deal

$274 or less

Good one-way deal

$253 or less
Provider with most accurate pricing for Chicago (CHI)-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Greenville flights.
Search Deals
From Illinois to Greenville
Search Deals
One-way flight from Illinois to Greenville
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Illinois to Greenville.
Search Deals
Price to beat on a one-way flight from Illinois to Greenville.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Illinois to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 7/21

5:40 am-1:10 pm

2 stops6h 30m

Greenville

Tue 7/28

7:00 am-1:05 pm

2 stops7h 05m

$257

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 8/8

11:15 am-7:00 pm

1 stop6h 45m

Greenville

Mon 8/10

4:40 pm-10:05 pm

2 stops6h 25m

$273

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 8/7

6:55 am-9:55 am

Nonstop2h 00m

Greenville

Mon 8/10

7:40 pm-11:31 pm

1 stop4h 51m

$279

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Fri 8/21

10:54 am-4:15 pm

1 stop4h 21m

Greenville

Sun 8/23

5:46 am-9:59 am

1 stop5h 13m

$289

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Sat 8/29

6:05 am-12:41 pm

1 stop5h 36m

Greenville

Sat 9/5

5:20 pm-10:36 pm

1 stop6h 16m

$289

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Fri 8/14

6:05 am-10:40 am

1 stop3h 35m

Greenville

Mon 8/24

7:15 am-12:39 pm

1 stop6h 24m

$289

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Thu 8/20

6:05 am-12:41 pm

1 stop5h 36m

Greenville

Sun 8/23

7:15 am-12:39 pm

1 stop6h 24m

$289

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Sat 8/8

4:39 pm-10:30 pm

1 stop4h 51m

Greenville

Sun 8/9

6:55 am-11:51 am

1 stop5h 56m

$289

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 9/17

5:30 am-11:03 am

1 stop4h 33m

Greenville

Mon 9/21

6:25 pm-11:59 pm

1 stop6h 34m

$289

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/8

5:30 am-12:41 pm

1 stop6h 11m

Greenville

Sun 8/9

5:20 pm-8:55 pm

1 stop4h 35m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/23

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Illinois to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Greenville

What is the cheapest month to book a flight from Illinois to Greenville?

Currently, June is the cheapest month in which you can book a flight from Illinois to Greenville (average of $146). Flying from Illinois to Greenville in February is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to GSP?

Find hourly flight availability from Illinois to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 26, 2026.

When flying from Illinois to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 8% versus a flight in the evening.

Weekly flight availability from Illinois to Greenville

Explore weekly flight availability from Illinois to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 26, 2026.

The most flights from USIL to GSP are scheduled on a Monday (20 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

How much does it cost to fly round-trip from Illinois to Greenville?

How far ahead should I book a flight from Illinois to Greenville?

To ensure you get the cheapest price possible for a flight from Illinois to Greenville, you should look to book at least 88 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest day to fly from Illinois to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Greenville. Price data was last updated on June 20, 2026.

Travelers seeking maximum savings on their Illinois to Greenville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Illinois to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Illinois?

    Located just 10.4 mi from the city center, Greenville (GSP) is the airport most travelers will use when flying to Greenville from Illinois.

  • How long is the flight from Illinois to Greenville?

    For as low as $279, Southwest can have you in Greenville from Illinois in 2h. Airlines will cover a distance of 577 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Illinois to Greenville one-way?

    One-way options have recently been found by users for as low as $108 on Delta. Other airlines that offer cheap prices include Southwest from $124 and American Airlines from $132 one-way.

  • What are the most popular routes from Illinois to Greenville?

    The most popular route from Illinois to Greenville is Chicago O'Hare Intl - Greenville. You may also consider Chicago Midway - Greenville or Lambert-St Louis - Greenville.

  • What are the most reliable airlines from Illinois to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Greenville on time: Republic Airways (96%), Avianca (81%), United Airlines (81%).

  • What are the cheapest flights from Illinois to Greenville?

    Looking at all options, your cheapest flight can be booked for $154. While the most popular route (Chicago O'Hare Intl - Greenville) can be booked for $240 on average, our data indicates $340 when flying from Illinois to Greenville.

  • Can I find deals for flights from Illinois to Greenville that include hotel bookings?

    Yes. In addition to deals on Illinois to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Greenville.

  • Can I find deals for business class flights from Illinois to Greenville?

    Yes. Cheapflights offers flight deals from Illinois to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Greenville?

    Currently, June is the cheapest month in which you can book a flight from Illinois to Greenville (average of $146). Flying from Illinois to Greenville in February is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

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Top 3 airlines flying from Illinois to Greenville

Discover the top 3 airlines that operate flights from Illinois to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$146Average$278FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$202Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$388FlexibilityNo cancel feeOn-time69%

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