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$98+ Cheap flights from Illinois to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GSP
Nov 14 — Nov 211
Fri 11/14
Fri 11/21
1 adult, Economy
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Cheap flight deals from Illinois to Greenville

Keep the following information in mind while searching for Illinois to Greenville flight deals. Data was last updated October 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$219
(American Airlines)

One-way from

$98
(United Airlines)

Popular in

November

Cheapest in

January

Average price

$344

Good round-trip deal

$229 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Chicago (CHI)-Greenville flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Greenville flights.
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From Illinois to Greenville
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One-way flight from Illinois to Greenville
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Highest demand for flights based on searches. 12% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Illinois to Greenville.
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Price to beat on a one-way flight from Illinois to Greenville.
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Find flight deals from Illinois to Greenville

Cheapest flights from Illinois to Greenville
Explore the most affordable flight options available from Illinois to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2025.

This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:51 pmORD - GSP
Nonstop1h 53mAmerican Airlines
Fri 11/148:14 pmGSP - ORD
Nonstop2h 16mAmerican Airlines
Deal found 10/12$219
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:55 pmMDW - GSP
1 stop5h 45mSouthwest
Thu 11/2010:35 amGSP - MDW
2 stops7h 00mSouthwest
Deal found 10/13$220
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:00 amORD - GSP
1 stop5h 26mAmerican Airlines
Wed 11/196:00 amGSP - ORD
Nonstop2h 17mAmerican Airlines
Deal found 10/14$220
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:10 amMDW - GSP
1 stop5h 31mDelta
Mon 11/107:59 pmGSP - MDW
1 stop4h 41mDelta
Deal found 10/14$222
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:35 pmORD - GSP
1 stop6h 31mDelta
Mon 11/177:59 pmGSP - ORD
1 stop5h 03mDelta
Deal found 10/14$222
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:34 pmORD - GSP
2 stops42h 31mMultiple Airlines
Wed 11/194:16 pmGSP - ORD
1 stop9h 11mMultiple Airlines
Deal found 10/14$225
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:35 amMDW - GSP
1 stop11h 00mSouthwest
Wed 11/1210:35 amGSP - MDW
2 stops7h 00mSouthwest
Deal found 10/14$226
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:05 amORD - GSP
Nonstop1h 53mAmerican Airlines
Tue 12/28:14 pmGSP - ORD
Nonstop2h 16mAmerican Airlines
Deal found 10/14$226
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:51 pmORD - GSP
Nonstop1h 53mAmerican Airlines
Mon 11/108:14 pmGSP - ORD
Nonstop2h 16mAmerican Airlines
Deal found 10/13$229
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:30 amMDW - GSP
2 stops31h 35mMultiple Airlines
Mon 11/173:40 pmGSP - MDW
1 stop9h 50mMultiple Airlines
Deal found 10/13$231
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:15 amORD - GSP
Nonstop1h 57mAmerican Airlines
Fri 11/218:00 amGSP - ORD
Nonstop2h 18mAmerican Airlines
Deal found 10/14$231
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:50 pmORD - GSP
1 stop6h 25mAmerican Airlines
Wed 11/126:00 amGSP - ORD
Nonstop2h 17mAmerican Airlines
Deal found 10/14$233

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 15, 2025.
Use the filters below to find and compare flights from Illinois to Greenville that are best for you.

Fly from

Illinois

Fly to

Greenville

Route

Depart

Return

Price

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Wed 11/19

12:55 pm-7:40 pm

1 stop5h 45m

Greenville

Thu 11/20

10:35 am-4:35 pm

2 stops7h 00m

$220

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 11/14

2:35 pm-10:06 pm

1 stop6h 31m

Greenville

Mon 11/17

7:59 pm-12:02 am

1 stop5h 03m

$222

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/10

2:30 pm-9:42 pm

1 stop6h 12m

Greenville

Sun 12/14

7:36 pm-12:02 am

1 stop5h 26m

$222

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 12/12

2:30 pm-9:42 pm

1 stop6h 12m

Greenville

Sun 12/14

7:25 am-1:50 pm

1 stop7h 25m

$229

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 11/28

8:48 am-11:47 am

Nonstop1h 59m

Greenville

Tue 12/2

9:19 am-10:33 am

Nonstop2h 14m

$233

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 3/12

6:30 pm-9:22 pm

Nonstop1h 52m

Greenville

Tue 3/17

1:11 pm-2:20 pm

Nonstop2h 09m

$238

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 10/28

8:50 am-2:20 pm

1 stop4h 30m

Greenville

Mon 11/3

5:28 pm-6:55 pm

Nonstop2h 27m

$239

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Fri 10/31

9:32 am-7:23 pm

1 stop8h 51m

Greenville

Sun 11/2

3:32 pm-8:32 am

1 stop18h 00m

$240

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sun 11/23

5:23 am-10:27 am

1 stop4h 04m

Greenville

Tue 12/2

7:25 am-1:50 pm

1 stop7h 25m

$247

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Wed 11/12

1:00 pm-8:49 pm

1 stop6h 49m

Greenville

Wed 11/19

12:30 pm-4:37 pm

1 stop5h 07m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 60 results
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Best time to book a flight from Illinois to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Greenville

What is the cheapest month to book a flight from Illinois to Greenville?

Currently, February is the cheapest month in which you can book a flight from Illinois to Greenville (average of $51). Flying from Illinois to Greenville in April is currently the most expensive (average of $141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to GSP?

Find hourly flight availability from Illinois to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 15, 2025.

When flying from Illinois to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 42% versus a flight in the morning.

What is the cheapest day to fly from Illinois to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Greenville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Illinois to Greenville flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Illinois to Greenville

Explore weekly flight availability from Illinois to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 15, 2025.

The most flights from USIL to GSP are scheduled on a Monday (24 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (22 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Illinois?

    Located just 10.4 mi from the city center, Greenville (GSP) is the airport most travelers will use when flying to Greenville from Illinois.

  • How long is the flight from Illinois to Greenville?

    For as low as $233, Southwest can have you in Greenville from Illinois in 1h 59m. Airlines will cover a distance of 577 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Illinois to Greenville one-way?

    One-way options have recently been found by users for as low as $98 on United Airlines. Other airlines that offer cheap prices include Delta from $99 and Southwest from $113 one-way.

  • What are the most popular routes from Illinois to Greenville?

    The most popular route from Illinois to Greenville is Chicago O'Hare Intl - Greenville. You may also consider Chicago Midway - Greenville or Lambert-St Louis - Greenville.

  • What are the most reliable airlines from Illinois to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Greenville on time: GoJet (87%), Republic Airways (87%), United Airlines (87%).

  • What are the cheapest flights from Illinois to Greenville?

    Looking at all options, your cheapest flight can be booked for $133. While the most popular route (Chicago O'Hare Intl - Greenville) can be booked for $195 on average, our data indicates $246 when flying from Illinois to Greenville.

  • Can I find deals for flights from Illinois to Greenville that include hotel bookings?

    Yes. In addition to deals on Illinois to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Greenville.

  • Can I find deals for business class flights from Illinois to Greenville?

    Yes. Cheapflights offers flight deals from Illinois to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Illinois to Greenville (average of $51). Flying from Illinois to Greenville in April is currently the most expensive (average of $141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Illinois to Greenville

Discover the top 3 airlines that operate flights from Illinois to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$148Average$276FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$202Average$330FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$371FlexibilityNo cancel feeOn-time69%

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