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$377+ Cheap flights from Knoxville to Greenville, NC (TYS - PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PGV
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Find flight deals from Knoxville to Greenville

Cheapest flights from Knoxville to Greenville
Explore the most affordable flight options available from Knoxville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:23 pmTYS - PGV
1 stop3h 42mAmerican Airlines
Sat 12/1310:58 amPGV - TYS
1 stop5h 57mAmerican Airlines
Deal found 11/24$407
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amTYS - PGV
2 stops12h 51mAmerican Airlines
Sun 12/145:59 pmPGV - TYS
1 stop4h 59mAmerican Airlines
Deal found 11/25$481

Cheap flight deals from Knoxville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Greenville (PGV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$377
(American Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Pitt-Greenville flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Pitt-Greenville flights.
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From Knoxville McGhee Tyson to Pitt-Greenville
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Knoxville to Greenville that are best for you.

Fly from

Knoxville

Fly to

Greenville

Route

Depart

Return

Price

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Tue 2/24

7:00 am-11:19 am

1 stop4h 19m

Pitt-Greenville

Sat 2/28

6:03 pm-10:00 pm

1 stop3h 57m

$377

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Tue 12/9

7:23 pm-11:05 pm

1 stop3h 42m

Pitt-Greenville

Sat 12/13

10:58 am-4:55 pm

1 stop5h 57m

$407

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Wed 12/10

6:05 am-12:12 pm

1 stop6h 07m

Pitt-Greenville

Sun 12/14

5:59 pm-10:58 pm

1 stop4h 59m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Compare providers for flights from Knoxville to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Greenville in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Greenville, North Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Greenville, North Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Greenville, North Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Greenville, North Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Greenville, North Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Greenville

What is the cheapest month to book a flight from Knoxville to Greenville, North Carolina?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Greenville, North Carolina (average of $113). Flying from Knoxville to Greenville, North Carolina in October is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 26, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Greenville, North Carolina?

    American Airlines can get you from Knoxville to Greenville, North Carolina in just under 4h 19m. Your travel time can differ by up to . The distance from Knoxville to Greenville, North Carolina is about 371 mi.

  • Can I find deals for flights from Knoxville to Greenville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Greenville.

  • Can I find deals for business class flights from Knoxville to Greenville?

    Yes. Cheapflights offers flight deals from Knoxville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Greenville, North Carolina?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Greenville, North Carolina (average of $113). Flying from Knoxville to Greenville, North Carolina in October is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

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Top airline flying from Knoxville to Greenville

Discover the top airline that operate flights from Knoxville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$398FlexibilityNo cancel feeOn-time71%

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