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$387+ Cheap flights from Knoxville to Greenville, NC (TYS - PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PGV
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Knoxville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Greenville (PGV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$387
(American Airlines)
From Knoxville McGhee Tyson to Pitt-Greenville
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Find flight deals from Knoxville to Greenville

Cheapest flights from Knoxville to Greenville
Explore the most affordable flight options available from Knoxville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/26:30 amTYS - PGV
1 stop4h 03mAmerican Airlines
lun. 10/63:09 pmPGV - TYS
1 stop4h 47mAmerican Airlines
Deal found 9/16$387
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3111:45 amTYS - PGV
1 stop3h 37mAmerican Airlines
dom. 11/25:00 amPGV - TYS
1 stop3h 34mAmerican Airlines
Deal found 9/16$442
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/47:45 pmTYS - PGV
1 stop3h 41mAmerican Airlines
mar. 10/76:00 amPGV - TYS
1 stop3h 52mAmerican Airlines
Deal found 9/16$474

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Knoxville to Greenville that are best for you.

Fly from

Knoxville

Fly to

Greenville

Route

Depart

Return

Price

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

jue. 10/2

6:30 am-10:33 am

1 stop4h 03m

Pitt-Greenville

lun. 10/6

3:09 pm-7:56 pm

1 stop4h 47m

$387

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

vie. 10/31

11:45 am-3:22 pm

1 stop3h 37m

Pitt-Greenville

dom. 11/2

5:00 am-8:34 am

1 stop3h 34m

$442

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

sáb. 10/4

7:45 pm-11:26 pm

1 stop3h 41m

Pitt-Greenville

mar. 10/7

6:00 am-9:52 am

1 stop3h 52m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Knoxville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Greenville

What is the cheapest month to book a flight from Knoxville to Greenville, North Carolina?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Greenville, North Carolina (average of $302). Flying from Knoxville to Greenville, North Carolina in June is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated septiembre 17, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Greenville, North Carolina?

    American Airlines can get you from Knoxville to Greenville, North Carolina in just under 4h 03m. Your travel time can differ by up to . The distance from Knoxville to Greenville, North Carolina is about 371 mi.

  • Can I find deals for flights from Knoxville to Greenville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Greenville.

  • Can I find deals for business class flights from Knoxville to Greenville?

    Yes. Cheapflights offers flight deals from Knoxville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Greenville, North Carolina?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Greenville, North Carolina (average of $302). Flying from Knoxville to Greenville, North Carolina in June is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

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Top airline flying from Knoxville to Greenville

Discover the top airline that operate flights from Knoxville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$398FlexibilityNo cancel feeOn-time71%

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