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Greenville

$92+ Cheap flights from Chicago (CHI) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — GSP
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Find cheap flights from Chicago to Greenville with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Chicago to Greenville are usually found in January or April, booked 89 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from Chicago to Greenville

Cheapest flights from Chicago to Greenville
Explore the most affordable flight options available from Chicago to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
MDW
-
GSP
1 stop5h 21m
Delta
Sat 4/185:50 pm
GSP
-
MDW
1 stop5h 38m
Delta
Deal found 2/10$157
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:25 am
ORD
-
GSP
1 stop4h 48m
Delta
Sun 3/87:59 pm
GSP
-
ORD
1 stop4h 55m
Delta
Deal found 2/13$157
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
MDW
-
GSP
1 stop4h 13m
Delta
Tue 3/105:40 am
GSP
-
MDW
1 stop5h 16m
Delta
Deal found 2/12$193
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:35 am
ORD
-
GSP
1 stop7h 06m
Delta
Sun 3/227:59 pm
GSP
-
ORD
1 stop4h 55m
Delta
Deal found 2/12$193
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:05 am
ORD
-
GSP
Nonstop1h 56m
United Airlines
Tue 3/175:32 pm
GSP
-
ORD
Nonstop2h 28m
United Airlines
Deal found 2/12$209
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:34 pm
ORD
-
GSP
1 stop22h 19m
Multiple Airlines
Mon 4/205:43 pm
GSP
-
ORD
1 stop28h 34m
Multiple Airlines
Deal found 2/13$214
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:45 am
ORD
-
GSP
1 stop6h 17m
Delta
Tue 3/36:49 am
GSP
-
ORD
1 stop4h 25m
Delta
Deal found 2/9$218
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:08 am
ORD
-
GSP
Nonstop2h 06m
United Airlines
Wed 6/247:42 pm
GSP
-
ORD
1 stop4h 39m
United Airlines
Deal found 2/11$219
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
MDW
-
GSP
1 stop4h 13m
Delta
Sun 3/88:30 am
GSP
-
MDW
1 stop4h 32m
Delta
Deal found 2/10$223
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:00 am
ORD
-
GSP
Nonstop1h 56m
United Airlines
Sun 4/56:30 am
GSP
-
ORD
Nonstop2h 24m
United Airlines
Deal found 2/10$223
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:00 pm
ORD
-
GSP
Nonstop2h 03m
American Airlines
Mon 5/48:14 pm
GSP
-
ORD
Nonstop2h 22m
American Airlines
Deal found 2/10$224
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
ORD
-
GSP
1 stop5h 03m
Delta
Sun 5/177:20 am
GSP
-
ORD
1 stop4h 07m
Delta
Deal found 2/13$228

Find flight deals from Chicago to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$157
(Delta)

One-way from

$92
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$276

Good round-trip deal

$229 or less

Good one-way deal

$144 or less
Provider with most accurate pricing for Chicago (CHI)-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Greenville flights.
Search Deals
From Chicago (CHI) to Greenville
Search Deals
One-way flight from Chicago (CHI) to Greenville
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($0 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to Greenville.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Chicago to Greenville that are best for you.

Fly from

Chicago

Fly to

Greenville

Route

Depart

Return

Price

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 3/5

5:25 am-11:13 am

1 stop4h 48m

Greenville

Sun 3/8

7:59 pm-11:54 pm

1 stop4h 55m

$157

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 3/6

5:37 pm-10:24 pm

1 stop3h 47m

Greenville

Sat 3/7

7:20 am-1:20 pm

1 stop7h 00m

$157

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 3/6

5:37 pm-10:24 pm

1 stop3h 47m

Greenville

Tue 3/10

11:40 am-4:46 pm

1 stop6h 06m

$157

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Fri 3/6

6:00 am-11:13 am

1 stop4h 13m

Greenville

Tue 3/10

5:40 am-9:56 am

1 stop5h 16m

$193

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 5/14

7:05 am-12:03 pm

1 stop3h 58m

Greenville

Sat 5/23

11:40 am-4:25 pm

1 stop5h 45m

$193

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 5/13

6:00 am-12:03 pm

1 stop5h 03m

Greenville

Sat 5/23

11:40 am-4:25 pm

1 stop5h 45m

$193

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 3/18

9:35 am-5:41 pm

1 stop7h 06m

Greenville

Sun 3/22

7:59 pm-11:54 pm

1 stop4h 55m

$193

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 4/15

8:00 pm-11:03 pm

Nonstop2h 03m

Greenville

Sat 4/18

7:30 am-8:56 am

Nonstop2h 26m

$209

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 3/17

7:05 am-10:01 am

Nonstop1h 56m

Greenville

Tue 3/17

5:32 pm-7:00 pm

Nonstop2h 28m

$209

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 3/3

2:46 pm-8:19 pm

1 stop4h 33m

Greenville

Tue 3/10

5:40 am-8:30 am

1 stop3h 50m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 38 results
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2
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4

Compare providers for flights from Chicago to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Greenville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Greenville

How far ahead should I book a flight from Chicago to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Greenville. Price data was last updated on February 6, 2026.

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Greenville?

Currently, December is the cheapest month in which you can book a flight from Chicago to Greenville (average of $56). Flying from Chicago to Greenville in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to GSP?

Find hourly flight availability from Chicago to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 13, 2026.

It’s optimal to fly from Chicago to Greenville in the morning. By choosing this option you can save up to 8% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from Chicago to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Greenville. Price data was last updated on February 7, 2026.

Travelers seeking maximum savings on their Chicago to Greenville flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Greenville

Explore weekly flight availability from Chicago to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 13, 2026.

The most flights from CHI to GSP are scheduled on a Wednesday (17 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (12 on average).

How much does it cost to fly round-trip from Chicago to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated February 13, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Chicago to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,193 reviews

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,193 reviews
Delta
7.9
Good
8,193 reviews

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,283 reviews
Delta
7.9
Good
8,193 reviews

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,279 reviews
Delta
7.9
Good
8,193 reviews

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Chicago?

    Greenville (GSP) is the airport you will fly into if you book a flight from Chicago to Greenville. You should not have trouble finding flights to Greenville from Chicago; the airport handles an average of 15 inbound flights from Chicago per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Greenville airport from Chicago. It is only a 10.4 mi journey from Greenville (GSP) to Greenville’s city center.

  • How long is the flight from Chicago to Greenville?

    For as low as $157, Delta can have you in Greenville from Chicago in 4h 48m. There are 577 mi between Chicago and Greenville.

  • What are the cheapest airlines flying from Chicago to Greenville round-trip?

    According to our current data, Delta ($118), American Airlines ($202), and United Airlines ($209) offers the cheapest pricing from Chicago to Greenville. Delta is 59% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Chicago to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $101. Southwest flights start at $108 while deals on American Airlines start at $133 one-way.

  • What are the most reliable airlines from Chicago to Greenville?

    Consider GoJet (75%), United Airlines (72%) or ANA (69%) when booking your flight. These represent the most reliable airlines when flying from Chicago to Greenville.

  • What are the cheapest flights from Chicago to Greenville?

    Looking at all options, your cheapest flight can be booked for $132. While the most popular route (Chicago O'Hare Intl - Greenville) can be booked for $157 on average, our data indicates $249 when flying from Chicago to Greenville.

  • Can I find deals for flights from Chicago to Greenville that include hotel bookings?

    Yes. In addition to deals on Chicago to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Greenville.

  • Can I find deals for business class flights from Chicago to Greenville?

    Yes. Cheapflights offers flight deals from Chicago to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Greenville?

    Currently, December is the cheapest month in which you can book a flight from Chicago to Greenville (average of $56). Flying from Chicago to Greenville in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Alternative routes for Chicago to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Chicago to Greenville

Discover the top 3 airlines that operate flights from Chicago to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$306FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$202Average$286FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$209Average$332FlexibilityNo cancel feeOn-time69%

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