$65+ Cheap flights from St. Louis (STL) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from St. Louis to Florida KeysExplore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:59 pm
STL
- EYW
1 stop15h 07m
Multiple Airlines
Fri 5/81:11 pm
EYW
- STL
2 stops20h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- EYW
1 stop19h 57m
Multiple Airlines
Sun 6/79:16 pm
EYW
- STL
1 stop27h 41m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:59 am
STL
- EYW
1 stop6h 24m
Delta
Wed 5/136:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/6![Delta logo]()
$253
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:12 pm
STL
- EYW
2 stops7h 46m
American Airlines
Wed 5/136:46 pm
EYW
- STL
1 stop6h 10m
American Airlines
Deal found 4/6![American Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
STL
- EYW
1 stop18h 08m
Multiple Airlines
Fri 5/1512:07 pm
EYW
- STL
2 stops30h 57m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:23 pm
STL
- EYW
2 stops35h 43m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop13h 16m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:20 am
STL
- EYW
1 stop4h 49m
Delta
Tue 8/187:00 am
EYW
- STL
1 stop4h 41m
Delta
Deal found 4/8![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
STL
- EYW
1 stop18h 08m
Multiple Airlines
Thu 5/1412:34 pm
EYW
- STL
2 stops45h 21m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:15 am
STL
- MIA
Nonstop2h 54m
American Airlines
Tue 6/98:33 am
MIA
- STL
Nonstop3h 02m
American Airlines
Deal found 4/8![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:33 pm
STL
- MIA
1 stop21h 58m
Frontier
Thu 7/166:00 am
MIA
- STL
1 stop9h 48m
Frontier
Deal found 4/5![Frontier logo]()
$276
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:08 pm
STL
- MIA
1 stop8h 25m
Frontier
Mon 6/88:03 pm
MIA
- STL
1 stop23h 05m
Frontier
Deal found 4/5![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:27 pm
STL
- MIA
1 stop28h 20m
Frontier
Sun 5/315:22 pm
MIA
- STL
1 stop16h 33m
Frontier
Deal found 4/7![Frontier logo]()
$278
Best flights from St. Louis to Florida KeysDiscover carefully curated flight deals from St. Louis to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from St. Louis to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:39 pm
STL
- EYW
1 stop5h 14m
Delta
Thu 7/96:18 pm
EYW
- STL
1 stop4h 54m
Delta
Deal found 4/5![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:25 am
STL
- MIA
2 stops9h 45m
Southwest
Wed 6/1011:45 am
MIA
- STL
2 stops11h 40m
Southwest
Deal found 4/6![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:25 am
STL
- MIA
1 stop24h 12m
United Airlines
Wed 5/67:40 pm
MIA
- STL
1 stop5h 44m
United Airlines
Deal found 4/5![United Airlines logo]()
$432
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:42 am
STL
- EYW
1 stop6h 58m
Delta
Sat 5/96:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/4![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:20 am
STL
- MIA
2 stops9h 40m
Southwest
Mon 5/115:30 am
MIA
- STL
2 stops10h 25m
Southwest
Deal found 4/8![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:02 pm
STL
- EYW
1 stop5h 38m
Delta
Sat 5/96:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/8![Delta logo]()
$374
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/143:55 pm
STL
- MIA
Nonstop2h 45m
Southwest
Sun 6/215:50 am
MIA
- STL
Nonstop2h 50m
Southwest
Deal found 4/5![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:10 pm
STL
- MIA
Nonstop2h 40m
Southwest
Wed 4/293:00 pm
MIA
- STL
Nonstop2h 55m
Southwest
Deal found 4/4![Southwest logo]()
$401
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:59 am
STL
- EYW
1 stop6h 24m
Delta
Sun 5/106:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/5![Delta logo]()
$406
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:11 pm
STL
- EYW
2 stops19h 51m
United Airlines
Wed 5/134:05 pm
EYW
- STL
1 stop6h 08m
United Airlines
Deal found 4/3![United Airlines logo]()
$501
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:15 pm
STL
- MIA
2 stops7h 45m
Southwest
Wed 5/137:00 am
MIA
- STL
2 stops9h 15m
Southwest
Deal found 4/6![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:30 pm
STL
- MIA
Nonstop2h 40m
Southwest
Mon 8/3112:25 pm
MIA
- STL
Nonstop2h 50m
Southwest
Deal found 4/8![Southwest logo]()
$439
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
STL
- EYW
1 stop5h 27m
Delta
Sun 5/106:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/6![Delta logo]()
$485
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/181:50 pm
STL
- MIA
Nonstop2h 40m
Southwest
Sun 5/248:05 am
MIA
- STL
1 stop4h 35m
Southwest
Deal found 4/7![Southwest logo]()
$441
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
STL
- EYW
1 stop7h 12m
United Airlines
Thu 4/302:49 pm
EYW
- STL
1 stop10h 08m
United Airlines
Deal found 4/5![United Airlines logo]()
$715
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:25 pm
STL
- MIA
1 stop7h 10m
Southwest
Tue 7/287:40 am
MIA
- STL
Nonstop2h 50m
Southwest
Deal found 4/6![Southwest logo]()
$449
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:30 pm
STL
- MIA
Nonstop2h 40m
Southwest
Fri 10/212:35 pm
MIA
- STL
1 stop7h 25m
Southwest
Deal found 4/3![Southwest logo]()
$449
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:02 pm
STL
- EYW
1 stop5h 38m
Delta
Tue 4/286:23 pm
EYW
- STL
1 stop6h 13m
Delta
Deal found 4/4![Delta logo]()
$621
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/283:45 pm
STL
- MIA
1 stop5h 20m
Southwest
Fri 7/35:40 am
MIA
- STL
Nonstop2h 50m
Southwest
Deal found 4/8![Southwest logo]()
$449
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:05 am
STL
- EYW
1 stop4h 22m
Delta
Fri 5/2211:48 am
EYW
- STL
1 stop5h 27m
Delta
Deal found 4/6![Delta logo]()
$621
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:25 pm
STL
- MIA
2 stops6h 40m
Southwest
Mon 6/85:35 am
MIA
- STL
2 stops7h 35m
Southwest
Deal found 4/4![Southwest logo]()
$451
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
STL
- EYW
1 stop5h 23m
Delta
Wed 7/86:18 pm
EYW
- STL
1 stop4h 54m
Delta
Deal found 4/5![Delta logo]()
$691
Last-minute flights from St. Louis to Florida KeysDiscover last-minute flight deals from St. Louis to Florida Keys. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Florida Keys. Data last updated April 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- MIA
1 stop8h 33m
Frontier
Fri 4/105:50 am
MIA
- STL
1 stop28h 58m
Frontier
Deal found 4/6![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:59 pm
STL
- MIA
2 stops23h 58m
Multiple Airlines
Sun 4/263:54 pm
MIA
- STL
1 stop15h 56m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:23 pm
STL
- EYW
2 stops35h 43m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop13h 16m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:59 pm
STL
- EYW
1 stop15h 07m
Multiple Airlines
Fri 5/81:11 pm
EYW
- STL
2 stops20h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$225
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:59 am
STL
- EYW
1 stop6h 24m
Delta
Wed 5/136:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 4/6![Delta logo]()
$253
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:12 pm
STL
- EYW
2 stops7h 46m
American Airlines
Wed 5/136:46 pm
EYW
- STL
1 stop6h 10m
American Airlines
Deal found 4/6![American Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
STL
- EYW
1 stop18h 08m
Multiple Airlines
Fri 5/1512:07 pm
EYW
- STL
2 stops30h 57m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
STL
- EYW
1 stop18h 08m
Multiple Airlines
Thu 5/1412:34 pm
EYW
- STL
2 stops45h 21m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:33 pm
STL
- MIA
1 stop27h 14m
Frontier
Sat 5/166:30 am
MIA
- STL
1 stop12h 34m
Frontier
Deal found 4/5![Frontier logo]()
$280
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
STL
- MIA
1 stop5h 56m
Delta
Wed 5/2010:35 am
MIA
- STL
1 stop6h 35m
Delta
Deal found 4/8![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:27 pm
STL
- MIA
1 stop28h 20m
Frontier
Sun 5/315:22 pm
MIA
- STL
1 stop16h 33m
Frontier
Deal found 4/7![Frontier logo]()
$278
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:15 am
STL
- MIA
Nonstop2h 54m
American Airlines
Tue 6/98:33 am
MIA
- STL
Nonstop3h 02m
American Airlines
Deal found 4/8![American Airlines logo]()
$275
One-way flights from St. Louis to Florida KeysSearch for one-way flight options from St. Louis to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from St. Louis to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- MIA
1 stop27h 14m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:27 pm
STL
- MIA
1 stop22h 00m
Frontier
Deal found 4/8![Frontier logo]()
$67
This Trip.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:21 am
STL
- MIA
1 stop5h 58m
Frontier
Deal found 4/8![Frontier logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:08 pm
STL
- MIA
1 stop8h 46m
Frontier
Deal found 4/5![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- MIA
1 stop27h 26m
Frontier
Deal found 4/4![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:21 am
STL
- MIA
1 stop10h 10m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
STL
- MIA
1 stop15h 57m
Frontier
Deal found 4/8![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:27 pm
STL
- MIA
1 stop18h 53m
Frontier
Deal found 4/6![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
- MIA
1 stop7h 48m
Frontier
Deal found 4/3![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- EYW
2 stops12h 58m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:27 pm
STL
- EYW
2 stops42h 04m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:33 pm
STL
- EYW
3 stops15h 33m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$150
Find flight deals from St. Louis to Florida Keys
Keep the following information in mind while searching for St. Louis to Florida Keys flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $220 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $395 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Fri 7/3
1:39 pm-7:53 pm
1 stop5h 14m
Key West
Thu 7/9
6:18 pm-10:12 pm
1 stop4h 54m
$339
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Wed 5/27
10:25 am-9:10 pm
2 stops9h 45m
Miami
Wed 6/10
11:45 am-10:25 pm
2 stops11h 40m
$367
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Sat 5/2
11:42 am-7:40 pm
1 stop6h 58m
Key West
Sat 5/9
6:19 pm-11:59 pm
1 stop6h 40m
$369
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Mon 5/4
1:02 pm-7:40 pm
1 stop5h 38m
Key West
Sat 5/9
6:19 pm-11:59 pm
1 stop6h 40m
$374
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Sat 5/2
6:20 am-5:00 pm
2 stops9h 40m
Miami
Mon 5/11
5:30 am-2:55 pm
2 stops10h 25m
$375
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Sun 6/14
3:55 pm-7:40 pm
Nonstop2h 45m
Miami
Sun 6/21
5:50 am-7:40 am
Nonstop2h 50m
$390
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Wed 4/22
1:10 pm-4:50 pm
Nonstop2h 40m
Miami
Wed 4/29
3:00 pm-4:55 pm
Nonstop2h 55m
$401
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Wed 5/6
9:59 am-5:23 pm
1 stop6h 24m
Key West
Sun 5/10
6:19 pm-11:59 pm
1 stop6h 40m
$406
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Sun 5/10
1:15 pm-10:00 pm
2 stops7h 45m
Miami
Wed 5/13
7:00 am-3:15 pm
2 stops9h 15m
$415
St. LouisMiami
STL - MIA
STLMIA
Lambert-St Louis
Tue 5/5
10:25 am-11:37 am
1 stop24h 12m
Miami
Wed 5/6
7:40 pm-12:24 am
1 stop5h 44m
$432
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from St. Louis with our price prediction graph.
STL-EYW
STL-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Florida Keys
STL-zzEOA
STL-EYW
STL-MIA
What is the cheapest month to book a flight from St. Louis to Florida Keys?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $222). Flying from St. Louis to Florida Keys in April is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 9, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Florida Keys
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Complete your trip
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Find flights from St. Louis to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Florida Keys flights
Browse other St. Louis and Florida Keys flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Florida Keys
Discover the top 3 airlines that operate flights from St. Louis to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$222 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$222 | Average$396 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$463 | FlexibilityNo cancel fee | On-time69% |