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Florida Keys

$80+ Cheap flights from St. Louis (STL) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from St. Louis to Florida Keys

Keep the following information in mind while searching for St. Louis to Florida Keys flight deals. Data was last updated July 31, 2025.

Round-trip from

$174
(American Airlines)

One-way from

$80
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$388
From Lambert-St Louis to Florida Keys
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One-way flight from Lambert-St Louis to Florida Keys
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Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from St. Louis to Florida Keys

Cheapest flights from St. Louis to Florida Keys
Explore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:26 amSTL - MIA
Nonstop2h 48mAmerican Airlines
Sat 8/3010:09 pmMIA - STL
Nonstop2h 50mAmerican Airlines
Deal found 7/30$174
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/312:30 pmSTL - MIA
1 stop17h 48mSpirit Airlines
Sat 9/64:53 pmMIA - STL
1 stop18h 57mSpirit Airlines
Deal found 7/30$192
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmSTL - MIA
1 stop6h 14mDelta
Sat 11/16:00 amMIA - STL
1 stop7h 35mDelta
Deal found 7/31$197
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:45 amSTL - MIA
1 stop5h 25mSouthwest
Wed 11/194:55 pmMIA - STL
Nonstop3h 00mSouthwest
Deal found 7/30$204
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:29 pmSTL - MIA
1 stop10h 01mFrontier
Sat 8/166:00 amMIA - STL
1 stop8h 59mFrontier
Deal found 7/30$218
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1310:15 amSTL - EYW
1 stop6h 00mDelta
Tue 9/167:00 amEYW - STL
1 stop6h 21mDelta
Deal found 7/29$223
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:49 amSTL - EYW
2 stops9h 33mAmerican Airlines
Tue 10/281:38 pmEYW - STL
1 stop8h 48mAmerican Airlines
Deal found 7/31$228

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.

Fly from

St. Louis

Fly to

Florida Keys

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 8/23

5:26 am-9:14 am

Nonstop2h 48m

Miami

Sat 8/30

10:09 pm-11:59 pm

Nonstop2h 50m

$174

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sun 8/31

2:30 pm-9:18 am

1 stop17h 48m

Miami

Sat 9/6

4:53 pm-10:50 am

1 stop18h 57m

$192

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 10/25

5:15 pm-12:29 am

1 stop6h 14m

Miami

Sat 11/1

6:00 am-12:35 pm

1 stop7h 35m

$197

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 8/13

7:29 pm-6:30 am

1 stop10h 01m

Miami

Sat 8/16

6:00 am-1:59 pm

1 stop8h 59m

$218

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 9/13

10:15 am-5:15 pm

1 stop6h 00m

Key West

Tue 9/16

7:00 am-12:21 pm

1 stop6h 21m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 10/22

8:49 am-7:22 pm

2 stops9h 33m

Key West

Tue 10/28

1:38 pm-9:26 pm

1 stop8h 48m

$228

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 10/18

7:00 am-8:30 pm

1 stop12h 30m

Miami

Sat 10/25

5:45 am-7:35 am

Nonstop2h 50m

$233

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 10/28

5:23 am-9:10 am

Nonstop2h 47m

$80

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 10/29

6:35 pm-10:15 pm

Nonstop2h 40m

$95

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 10/29

7:05 am-3:30 pm

1 stop7h 25m

$99

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 17 results
1
2

Best time to book a flight from St. Louis to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Florida Keys

What is the cheapest month to book a flight from St. Louis to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated July 31, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from St. Louis to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Spirit Airlines
6.3
Okay
8,049 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,239 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Florida Keys?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Florida Keys from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to Florida Keys one-way?

    The cheapest airlines for a one-way flight from St. Louis to Florida Keys are American Airlines ($80), Southwest ($95), and Delta ($99).

  • Can I find deals for flights from St. Louis to Florida Keys that include hotel bookings?

    Yes. In addition to deals on St. Louis to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Florida Keys.

  • Can I find deals for business class flights from St. Louis to Florida Keys?

    Yes. Cheapflights offers flight deals from St. Louis to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Florida Keys

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Top 3 airlines flying from St. Louis to Florida Keys

Discover the top 3 airlines that operate flights from St. Louis to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$450FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$245Average$536FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$424FlexibilityNo cancel feeOn-time71%

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