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Florida Keys

$70+ Cheap flights from St. Louis (STL) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from St. Louis to Florida Keys

Keep the following information in mind while searching for St. Louis to Florida Keys flight deals. Data was last updated junio 12, 2025.

Round-trip from

$199
(American Airlines)

One-way from

$70
(Spirit)

Popular in

March

Cheapest in

August

Average price

$429
From Lambert-St Louis to Florida Keys
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One-way flight from Lambert-St Louis to Florida Keys
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Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from St. Louis to Florida Keys

Cheapest flights from St. Louis to Florida Keys
Explore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/281:29 pmSTL - MIA
1 stop5h 04mDelta
jue. 7/315:30 amMIA - STL
1 stop5h 11mDelta
Deal found 6/12$201
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/307:54 pmSTL - MIA
1 stop9h 36mMultiple Airlines
dom. 9/77:58 pmMIA - STL
1 stop12h 51mMultiple Airlines
Deal found 6/9$208
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/247:54 pmSTL - MIA
1 stop9h 36mFrontier
sáb. 8/307:05 amMIA - STL
1 stop7h 28mFrontier
Deal found 6/11$213
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/15:22 amSTL - MIA
Nonstop2h 48mAmerican Airlines
sáb. 9/610:09 pmMIA - STL
Nonstop2h 50mAmerican Airlines
Deal found 6/11$214
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/198:44 amSTL - MIA
1 stop9h 09mSpirit Airlines
dom. 9/215:30 pmMIA - STL
2 stops15h 19mSpirit Airlines
Deal found 6/10$218
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/237:32 amSTL - EYW
1 stop7h 47mAmerican Airlines
sáb. 8/307:40 pmEYW - STL
1 stop5h 19mAmerican Airlines
Deal found 6/11$223
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/18:05 amSTL - MIA
Nonstop2h 50mSouthwest
vie. 7/45:55 amMIA - STL
Nonstop2h 50mSouthwest
Deal found 6/11$224
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/261:23 pmSTL - EYW
1 stop5h 26mDelta
mié. 7/306:27 pmEYW - STL
1 stop6h 26mDelta
Deal found 6/11$257
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/48:20 amSTL - EYW
2 stops26h 55mUnited Airlines
dom. 9/76:45 pmEYW - STL
2 stops25h 13mUnited Airlines
Deal found 6/9$354
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/86:15 amSTL - MIA
1 stop8h 32mUnited Airlines
mié. 10/156:05 amMIA - STL
2 stops10h 39mUnited Airlines
Deal found 6/10$362
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/2410:47 amSTL - EYW
3 stops28h 49mMultiple Airlines
mié. 7/3010:02 amEYW - STL
2 stops24h 50mMultiple Airlines
Deal found 6/11$374

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.

Fly from

St. Louis

Fly to

Florida Keys

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

lun. 7/28

1:29 pm-7:33 pm

1 stop5h 04m

Miami

jue. 7/31

5:30 am-9:41 am

1 stop5h 11m

$201

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

sáb. 8/30

7:54 pm-6:30 am

1 stop9h 36m

Miami

dom. 9/7

7:58 pm-7:49 am

1 stop12h 51m

$208

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

dom. 8/24

7:54 pm-6:30 am

1 stop9h 36m

Miami

sáb. 8/30

7:05 am-1:33 pm

1 stop7h 28m

$213

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

lun. 9/1

5:22 am-9:10 am

Nonstop2h 48m

Miami

sáb. 9/6

10:09 pm-11:59 pm

Nonstop2h 50m

$214

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

dom. 8/3

10:47 am-10:11 am

1 stop22h 24m

Miami

jue. 8/7

4:51 pm-9:52 am

1 stop18h 01m

$220

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

sáb. 8/23

7:32 am-4:19 pm

1 stop7h 47m

Key West

sáb. 8/30

7:40 pm-11:59 pm

1 stop5h 19m

$223

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

mar. 7/1

8:05 am-11:55 am

Nonstop2h 50m

Miami

vie. 7/4

5:55 am-7:45 am

Nonstop2h 50m

$224

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

sáb. 7/26

1:23 pm-7:49 pm

1 stop5h 26m

Key West

mié. 7/30

6:27 pm-11:53 pm

1 stop6h 26m

$257

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

lun. 9/1

8:20 am-3:46 pm

1 stop6h 26m

Miami

sáb. 9/6

7:28 am-3:44 pm

2 stops9h 16m

$337

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

jue. 9/4

8:20 am-12:15 pm

2 stops26h 55m

Key West

dom. 9/7

6:45 pm-6:58 pm

2 stops25h 13m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 21 results
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Best time to book a flight from St. Louis to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Florida Keys

What is the cheapest month to book a flight from St. Louis to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated junio 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from St. Louis to Florida Keys by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,946 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Spirit Airlines
6.3
Okay
8,052 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Florida Keys?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Florida Keys from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to Florida Keys one-way?

    The cheapest airlines for a one-way flight from St. Louis to Florida Keys are Spirit Airlines ($70), Southwest ($89), and Delta ($101).

  • Can I find deals for flights from St. Louis to Florida Keys that include hotel bookings?

    Yes. In addition to deals on St. Louis to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Florida Keys.

  • Can I find deals for business class flights from St. Louis to Florida Keys?

    Yes. Cheapflights offers flight deals from St. Louis to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Florida Keys

Discover the top 3 airlines that operate flights from St. Louis to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$224Average$453FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$231Average$427FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$245Average$536FlexibilityNo cancel feeOn-time69%

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