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$72+ Cheap flights from Mississippi to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — EYW
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Find flight deals from Mississippi to Florida Keys

Cheapest flights from Mississippi to Florida Keys
Explore the most affordable flight options available from Mississippi to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:26 pmGPT - MIA
1 stop5h 23mAmerican Airlines
Sat 11/86:00 amMIA - GPT
1 stop7h 23mAmerican Airlines
Deal found 10/20$217
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:26 pmMEM - EYW
1 stop17h 38mAllegiant Air
Thu 12/114:34 pmEYW - MEM
1 stop22h 52mAllegiant Air
Deal found 10/21$229
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:57 pmGPT - MIA
1 stop7h 01mUnited Airlines
Sun 11/96:25 amMIA - GPT
1 stop5h 52mUnited Airlines
Deal found 10/21$231
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:12 pmMOB - MIA
1 stop4h 34mDelta
Wed 12/310:43 amMIA - MOB
1 stop5h 18mDelta
Deal found 10/20$249
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:45 amMEM - MIA
1 stop4h 20mSouthwest
Sat 12/136:20 amMIA - MEM
2 stops8h 00mSouthwest
Deal found 10/21$249
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:39 amBTR - MIA
1 stop5h 56mDelta
Mon 11/176:23 pmMIA - BTR
1 stop4h 29mDelta
Deal found 10/20$249
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:15 pmJAN - EYW
1 stop4h 00mDelta
Tue 12/166:10 pmEYW - JAN
1 stop5h 52mDelta
Deal found 10/19$249
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:10 pmMEM - MIA
1 stop9h 09mMultiple Airlines
Sun 11/163:04 pmMIA - MEM
2 stops29h 56mMultiple Airlines
Deal found 10/20$250
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:40 pmMEM - EYW
1 stop18h 26mMultiple Airlines
Thu 12/2510:59 amEYW - MEM
1 stop8h 32mMultiple Airlines
Deal found 10/19$251
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/27:25 pmMEM - MIA
2 stops36h 47mMultiple Airlines
Thu 11/66:00 amMIA - MEM
1 stop14h 22mMultiple Airlines
Deal found 10/20$257
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/43:40 pmBTR - MIA
1 stop4h 11mDelta
Sat 11/86:00 amMIA - BTR
1 stop4h 37mDelta
Deal found 10/20$257
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:15 pmMOB - MIA
1 stop5h 43mUnited Airlines
Sun 11/96:25 amMIA - MOB
1 stop6h 16mUnited Airlines
Deal found 10/21$259

Cheap flight deals from Mississippi to Florida Keys

Keep the following information in mind while searching for Mississippi to Florida Keys flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(American Airlines)

One-way from

$72
(Frontier)

Popular in

December

Cheapest in

September

Average price

$346
Provider with most accurate pricing for Jackson-Evers Intl-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Miami flights.
Search Deals
From Mississippi to Florida Keys
Search Deals
One-way flight from Mississippi to Florida Keys
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Mississippi to Florida Keys that are best for you.

Fly from

Mississippi

Fly to

Florida Keys

Route

Depart

Return

Price

GulfportMiami

GPT - MIA

GPTMIA

Gulfport Biloxi Regional

Wed 11/5

1:57 pm-9:58 pm

1 stop7h 01m

Miami

Sun 11/9

6:25 am-11:17 am

1 stop5h 52m

$231

JacksonMiami

JAN - MIA

JANMIA

Jackson-Evers Intl

Sat 2/14

2:03 pm-9:59 pm

1 stop6h 56m

Miami

Sat 2/21

6:15 am-1:26 pm

1 stop8h 11m

$239

GulfportMiami

GPT - MIA

GPTMIA

Gulfport Biloxi Regional

Sat 3/21

2:00 pm-9:50 pm

1 stop6h 50m

Miami

Tue 3/31

9:00 am-4:02 pm

1 stop8h 02m

$243

MobileMiami

MOB - MIA

MOBMIA

Mobile

Mon 11/24

7:12 pm-12:46 am

1 stop4h 34m

Miami

Wed 12/3

10:43 am-3:01 pm

1 stop5h 18m

$249

MobileMiami

MOB - MIA

MOBMIA

Mobile

Fri 12/5

5:30 pm-11:52 pm

1 stop5h 22m

Miami

Sun 12/7

6:00 am-10:30 am

1 stop5h 30m

$249

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Sat 1/17

4:40 pm-9:35 pm

1 stop3h 55m

Miami

Tue 1/27

7:15 am-1:55 pm

2 stops7h 40m

$249

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Mon 11/10

7:39 am-2:35 pm

1 stop5h 56m

Miami

Mon 11/17

6:23 pm-9:52 pm

1 stop4h 29m

$249

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Wed 2/18

6:00 am-2:39 pm

1 stop7h 39m

Miami

Sat 2/21

6:00 am-9:44 am

1 stop4h 44m

$249

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Thu 1/29

7:00 pm-12:57 am

1 stop4h 57m

Miami

Sat 2/7

7:00 am-12:54 pm

1 stop6h 54m

$249

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Thu 1/15

9:30 am-6:25 pm

1 stop7h 55m

Miami

Fri 1/23

11:05 am-5:53 pm

1 stop7h 48m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Florida Keys

What is the cheapest month to book a flight from Mississippi to Florida Keys?

Currently, June is the cheapest month in which you can book a flight from Mississippi to Florida Keys (average of $212). Flying from Mississippi to Florida Keys in January is currently the most expensive (average of $696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Florida Keys?

    Departing from Mississippi to Florida Keys will take you 4h 34m. Airlines will cover a distance of 590 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Florida Keys one-way?

    $85 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Allegiant Air and American Airlines, with prices starting from $98 and $109, respectively.

  • Can I find deals for flights from Mississippi to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Mississippi to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Florida Keys.

  • Can I find deals for business class flights from Mississippi to Florida Keys?

    Yes. Cheapflights offers flight deals from Mississippi to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Florida Keys?

    Currently, June is the cheapest month in which you can book a flight from Mississippi to Florida Keys (average of $212). Flying from Mississippi to Florida Keys in January is currently the most expensive (average of $696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Florida Keys

Discover the top 2 airlines that operate flights from Mississippi to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$560FlexibilityNo cancel feeOn-timeN/A

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