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$356+ Cheap flights from Orlando (ORL) to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
ORL — FLO
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Orlando to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Orlando (ORL) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$356
(American Airlines)
From Orlando (ORL) to Florence
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Find flight deals from Orlando to Florence

Cheapest flights from Orlando to Florence
Explore the most affordable flight options available from Orlando to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2712:11 pmMCO - FLO
2 stops11h 05mAmerican Airlines
Sat 10/46:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Deal found 8/14$356
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/307:06 amMCO - FLO
2 stops10h 19mAmerican Airlines
Wed 9/36:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Deal found 8/14$366
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2811:49 amMCO - FLO
1 stop4h 43mAmerican Airlines
Sun 10/54:57 pmFLO - MCO
1 stop4h 02mAmerican Airlines
Deal found 8/14$440
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/296:15 amMCO - FLO
1 stop4h 24mAmerican Airlines
Tue 9/212:11 pmFLO - MCO
1 stop3h 47mAmerican Airlines
Deal found 8/13$472

Cheapflights Fare Finder

 
Customize your flight search to find flights from Orlando to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Orlando to Florence that are best for you.

Fly from

Orlando

Fly to

Florence

Route

Depart

Return

Price

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Sat 9/27

12:11 pm-11:16 pm

2 stops11h 05m

Florence

Sat 10/4

6:14 am-7:44 pm

2 stops13h 30m

$356

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Sun 9/28

11:49 am-4:32 pm

1 stop4h 43m

Florence

Sun 10/5

4:57 pm-8:59 pm

1 stop4h 02m

$440

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Fri 8/29

6:15 am-10:39 am

1 stop4h 24m

Florence

Tue 9/2

12:11 pm-3:58 pm

1 stop3h 47m

$472

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 9/11

11:49 am-4:32 pm

1 stop4h 43m

Florence

Thu 9/18

4:57 pm-10:24 pm

1 stop5h 27m

$477

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Orlando to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Orlando with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Orlando to Florence

What is the cheapest month to book a flight from Orlando to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Orlando to Florence, South Carolina (average of $366). Flying from Orlando to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Orlando to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Orlando?

    If you book a flight to Florence from Orlando, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence. There are 0 flights from Orlando to Florence per day from 0 different airlines.

  • Can I find deals for flights from Orlando to Florence that include hotel bookings?

    Yes. In addition to deals on Orlando to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Orlando to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orlando to Florence.

  • Can I find deals for business class flights from Orlando to Florence?

    Yes. Cheapflights offers flight deals from Orlando to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Orlando to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Orlando to Florence, South Carolina (average of $366). Flying from Orlando to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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