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$427+ Cheap flights from Jackson, MS to Florence, SC (JAN - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FLO
Jun 2 — Jun 91
Tue 6/2
Tue 6/9
1 adult, Economy
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Cheap flight deals from Jackson to Florence

Cheapest flights from Jackson to Florence
Explore the most affordable flight options available from Jackson to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:14 am
JAN
-
FLO
1 stop4h 56m
American Airlines
Tue 6/162:35 pm
FLO
-
JAN
1 stop6h 24m
American Airlines
Deal found 4/30$447
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:20 am
JAN
-
FLO
1 stop5h 50m
American Airlines
Sat 7/252:35 pm
FLO
-
JAN
2 stops9h 46m
American Airlines
Deal found 5/1$452

Find flight deals from Jackson to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Jackson (JAN) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$447
(American Airlines)

One-way from

$427
(American Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Florence flights.
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From Jackson-Evers Intl to Florence
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One-way flight from Jackson-Evers Intl to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Jackson to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Jackson to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

JacksonFlorence

JAN - FLO

JANFLO

Jackson-Evers Intl

Sat 6/6

8:14 am-2:10 pm

1 stop4h 56m

Florence

Tue 6/16

2:35 pm-7:59 pm

1 stop6h 24m

$447

JacksonFlorence

JAN - FLO

JANFLO

Jackson-Evers Intl

Sat 7/18

7:20 am-2:10 pm

1 stop5h 50m

Florence

Sat 7/25

2:35 pm-11:21 pm

2 stops9h 46m

$452
Cheapest one-way
Quickest one-way

JacksonFlorence

JAN - FLO

JANFLO

Jackson-Evers Intl

Sun 5/24

8:15 am-2:10 pm

1 stop4h 55m

$427

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Jackson, Mississippi-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jackson, Mississippi-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jackson, Mississippi-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jackson, Mississippi-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jackson, Mississippi-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jackson to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Jackson with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Jackson to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jackson, Mississippi to Florence, South Carolina?

    A quick flight from Jackson, Mississippi to Florence, South Carolina can take about 4h 56m. American Airlines provides one of the quickest options available for as low as $447. Jackson, Mississippi and Florence, South Carolina are separated by a distance of 611 mi.

  • Can I find deals for flights from Jackson to Florence that include hotel bookings?

    Yes. In addition to deals on Jackson to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jackson to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jackson to Florence.

  • Can I find deals for business class flights from Jackson to Florence?

    Yes. Cheapflights offers flight deals from Jackson to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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