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$368+ Cheap flights from Buffalo to Florence, SC (BUF - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — FLO
ago. 23 — ago. 301
sáb. 8/23
sáb. 8/30
1 adult, Economy
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Cheap flight deals from Buffalo to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 18, 2025.

Round-trip from

$368
(American Airlines)
From Buffalo to Florence
Search Deals

Find flight deals from Buffalo to Florence

Cheapest flights from Buffalo to Florence
Explore the most affordable flight options available from Buffalo to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/276:00 amBUF - FLO
2 stops11h 12mAmerican Airlines
mar. 9/306:14 amFLO - BUF
2 stops10h 48mAmerican Airlines
Deal found 8/17$368
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/277:35 amBUF - FLO
1 stop4h 11mAmerican Airlines
sáb. 8/302:34 pmFLO - BUF
1 stop4h 14mAmerican Airlines
Deal found 8/17$429
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/316:15 amBUF - FLO
1 stop4h 35mAmerican Airlines
lun. 9/86:14 amFLO - BUF
1 stop5h 56mAmerican Airlines
Deal found 8/18$543
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:13 amBUF - FLO
1 stop4h 04mAmerican Airlines
dom. 12/282:31 pmFLO - BUF
1 stop3h 27mAmerican Airlines
Deal found 8/17$551
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/16:15 amBUF - FLO
1 stop4h 24mAmerican Airlines
vie. 9/56:14 amFLO - BUF
1 stop5h 56mAmerican Airlines
Deal found 8/17$765

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Buffalo to Florence that are best for you.

Fly from

Buffalo

Fly to

Florence

Route

Depart

Return

Price

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

sáb. 9/27

6:00 am-5:12 pm

2 stops11h 12m

Florence

mar. 9/30

6:14 am-5:02 pm

2 stops10h 48m

$368

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

mié. 8/27

7:35 am-11:46 am

1 stop4h 11m

Florence

sáb. 8/30

2:34 pm-6:48 pm

1 stop4h 14m

$429

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

dom. 8/31

6:15 am-10:50 am

1 stop4h 35m

Florence

lun. 9/8

6:14 am-12:10 pm

1 stop5h 56m

$543

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

lun. 9/1

6:15 am-10:39 am

1 stop4h 24m

Florence

vie. 9/5

6:14 am-12:10 pm

1 stop5h 56m

$765

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Buffalo to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Florence

What is the cheapest month to book a flight from Buffalo to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Florence, South Carolina (average of $366). Flying from Buffalo to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to FLO?

Find hourly flight availability from Buffalo to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Buffalo to Florence, South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated agosto 18, 2025.
See what other customers who have flown with American Airlines from Buffalo to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.5

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.5

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Florence, South Carolina?

    Airlines like American Airlines fly from Buffalo to Florence, South Carolina in about 11h 12m. The time it takes to get you to your destination can typically vary by up to . Buffalo and Florence, South Carolina are separated by a distance of 607 mi.

  • What is the cheapest airline to fly from Buffalo to Florence, South Carolina round-trip?

    American Airlines, at $199, was found to be the cheapest airline from Buffalo to Florence, South Carolina..

  • Can I find deals for flights from Buffalo to Florence that include hotel bookings?

    Yes. In addition to deals on Buffalo to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Florence.

  • Can I find deals for business class flights from Buffalo to Florence?

    Yes. Cheapflights offers flight deals from Buffalo to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Florence, South Carolina (average of $366). Flying from Buffalo to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Buffalo to Florence

Discover the top airline that operate flights from Buffalo to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$199Average$560FlexibilityNo cancel feeOn-time71%

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