Currently, January is the cheapest month in which you can book a flight from Buffalo to Florence, South Carolina (average of $366). Flying from Buffalo to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
A simple way to save on the total cost of your ticket is to fly from Buffalo to Florence, South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.