South Carolina

$82+ Cheap flights from Buffalo (BUF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
jun. 3 — jun. 101
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Cheap flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/32:49 pm
BUF
-
CHS
2 stops17h 49m
Multiple Airlines
mar. 6/93:13 pm
CHS
-
BUF
1 stop27h 59m
Multiple Airlines
Deal found 5/2$221
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/184:10 pm
BUF
-
SAV
1 stop4h 20m
Southwest
jue. 6/257:55 pm
SAV
-
BUF
1 stop4h 15m
Southwest
Deal found 5/3$246
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/177:44 pm
BUF
-
CHS
2 stops36h 54m
Multiple Airlines
mar. 6/93:13 pm
CHS
-
BUF
1 stop27h 59m
Multiple Airlines
Deal found 5/2$247
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/266:29 am
BUF
-
SAV
1 stop4h 16m
Delta
vie. 7/37:38 am
SAV
-
BUF
1 stop7h 31m
Delta
Deal found 4/30$251
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/256:00 am
BUF
-
SAV
2 stops8h 11m
United Airlines
sáb. 8/293:14 pm
SAV
-
BUF
1 stop5h 54m
United Airlines
Deal found 5/3$256
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/297:52 pm
BUF
-
CHS
1 stop12h 56m
Multiple Airlines
vie. 6/59:28 pm
CHS
-
BUF
2 stops37h 13m
Multiple Airlines
Deal found 4/30$256
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/294:55 pm
BUF
-
CHS
1 stop6h 01m
Delta
lun. 6/16:38 pm
CHS
-
BUF
1 stop5h 21m
Delta
Deal found 4/29$257
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/288:49 pm
BUF
-
MYR
1 stop12h 16m
Multiple Airlines
jue. 6/46:00 am
MYR
-
BUF
2 stops31h 54m
Multiple Airlines
Deal found 4/30$261
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/277:52 pm
BUF
-
CHS
1 stop12h 46m
Multiple Airlines
lun. 6/19:28 pm
CHS
-
BUF
2 stops40h 26m
Multiple Airlines
Deal found 4/30$261
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/26:02 am
BUF
-
CHS
2 stops6h 06m
American Airlines
mar. 6/27:47 pm
CHS
-
BUF
1 stop4h 09m
American Airlines
Deal found 4/29$262
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/254:49 pm
BUF
-
SAV
1 stop6h 22m
American Airlines
sáb. 8/295:16 am
SAV
-
BUF
2 stops7h 22m
American Airlines
Deal found 4/30$263
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/176:05 am
BUF
-
SAV
1 stop4h 42m
American Airlines
sáb. 10/176:39 pm
SAV
-
BUF
1 stop5h 17m
American Airlines
Deal found 4/30$267

Find flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated mayo 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$82
(CheapOair)

Popular in

March

Cheapest in

September

Average price

$372
Provider with most accurate pricing for Buffalo-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Buffalo-Myrtle Beach Intl flights.
From Buffalo to South Carolina
One-way flight from Buffalo to South Carolina
Highest demand for flights based on searches. 13% potential increase in price ($54 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 4, 2026.
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

mar. 10/13

4:30 pm-8:47 pm

1 stop4h 17m

Savannah/Hilton Head

jue. 10/15

6:50 pm-11:55 pm

1 stop5h 05m

$251

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

jue. 8/20

7:19 pm-12:21 am

1 stop5h 02m

Savannah/Hilton Head

vie. 8/21

5:35 am-11:11 am

1 stop5h 36m

$251

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

vie. 8/21

7:19 pm-12:21 am

1 stop5h 02m

Savannah/Hilton Head

mar. 8/25

5:35 am-11:11 am

1 stop5h 36m

$251

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

jue. 9/24

7:40 pm-12:04 am

1 stop4h 24m

Savannah/Hilton Head

dom. 9/27

7:50 pm-11:58 pm

1 stop4h 08m

$251

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

mié. 6/3

7:00 pm-11:52 pm

1 stop4h 52m

Charleston

mar. 6/9

3:08 pm-9:03 pm

1 stop5h 55m

$257

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

mié. 6/17

5:12 pm-10:06 pm

1 stop4h 54m

Charleston

lun. 6/22

6:39 pm-12:03 am

1 stop5h 24m

$257

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

vie. 8/14

12:01 pm-5:58 pm

1 stop5h 57m

Charleston

lun. 8/17

6:21 pm-11:29 pm

1 stop5h 08m

$257

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

sáb. 6/6

7:00 am-12:12 pm

1 stop5h 12m

Charleston

jue. 6/11

6:24 pm-11:59 pm

1 stop5h 35m

$257

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

dom. 5/24

12:50 pm-8:10 pm

2 stops7h 20m

Charleston

jue. 5/28

4:45 pm-11:20 pm

1 stop6h 35m

$262

BuffaloHilton Head Island

BUF - HHH

BUFHHH

Buffalo

mar. 6/9

6:03 am-11:31 am

1 stop5h 28m

Hilton Head Island

vie. 6/12

4:15 pm-11:32 pm

1 stop7h 17m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

How far ahead should I book a flight from Buffalo to South Carolina?

The price you pay for your flight from Buffalo to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, June is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $80). Flying from Buffalo to South Carolina in January is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated mayo 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Buffalo to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Buffalo to South Carolina?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South Carolina. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to South Carolina?

    Airlines like Delta, United Airlines, and Southwest fly from Buffalo to South Carolina in about 4h 11m. The time it takes to get you to your destination can typically vary by up to 14m. The distance between Buffalo and South Carolina is about 697 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are JetBlue ($90), Delta ($98), and American Airlines ($100).

  • What are the most popular routes from Buffalo to South Carolina?

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $80). Flying from Buffalo to South Carolina in January is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Buffalo to South Carolina

Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$80Average$232FlexibilityNo cancel feeOn-time62%
DeltaCheapest$108Average$335FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$353FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$200Average$279FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$236Average$410FlexibilityNo cancel feeOn-time63%

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