$82+ Cheap flights from Buffalo (BUF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
jun. 3 — jun. 101
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South Carolina with Cheapflights
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Cheapest flights from Buffalo to South CarolinaExplore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 4, 2026.
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/32:49 pm
BUF
- CHS
2 stops17h 49m
Multiple Airlines
mar. 6/93:13 pm
CHS
- BUF
1 stop27h 59m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/184:10 pm
BUF
- SAV
1 stop4h 20m
Southwest
jue. 6/257:55 pm
SAV
- BUF
1 stop4h 15m
Southwest
Deal found 5/3![Southwest logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/177:44 pm
BUF
- CHS
2 stops36h 54m
Multiple Airlines
mar. 6/93:13 pm
CHS
- BUF
1 stop27h 59m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/266:29 am
BUF
- SAV
1 stop4h 16m
Delta
vie. 7/37:38 am
SAV
- BUF
1 stop7h 31m
Delta
Deal found 4/30![Delta logo]()
$251
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/256:00 am
BUF
- SAV
2 stops8h 11m
United Airlines
sáb. 8/293:14 pm
SAV
- BUF
1 stop5h 54m
United Airlines
Deal found 5/3![United Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/297:52 pm
BUF
- CHS
1 stop12h 56m
Multiple Airlines
vie. 6/59:28 pm
CHS
- BUF
2 stops37h 13m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$256
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/294:55 pm
BUF
- CHS
1 stop6h 01m
Delta
lun. 6/16:38 pm
CHS
- BUF
1 stop5h 21m
Delta
Deal found 4/29![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/288:49 pm
BUF
- MYR
1 stop12h 16m
Multiple Airlines
jue. 6/46:00 am
MYR
- BUF
2 stops31h 54m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/277:52 pm
BUF
- CHS
1 stop12h 46m
Multiple Airlines
lun. 6/19:28 pm
CHS
- BUF
2 stops40h 26m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/26:02 am
BUF
- CHS
2 stops6h 06m
American Airlines
mar. 6/27:47 pm
CHS
- BUF
1 stop4h 09m
American Airlines
Deal found 4/29![American Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/254:49 pm
BUF
- SAV
1 stop6h 22m
American Airlines
sáb. 8/295:16 am
SAV
- BUF
2 stops7h 22m
American Airlines
Deal found 4/30![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/176:05 am
BUF
- SAV
1 stop4h 42m
American Airlines
sáb. 10/176:39 pm
SAV
- BUF
1 stop5h 17m
American Airlines
Deal found 4/30![American Airlines logo]()
$267
Best flights from Buffalo to South CarolinaDiscover carefully curated flight deals from Buffalo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mayo 4, 2026.
Discover carefully curated flight deals from Buffalo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mayo 4, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/134:30 pm
BUF
- SAV
1 stop4h 17m
Delta
jue. 10/156:50 pm
SAV
- BUF
1 stop5h 05m
Delta
Deal found 5/3![Delta logo]()
$251
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/37:00 pm
BUF
- CHS
1 stop4h 52m
United Airlines
mar. 6/93:08 pm
CHS
- BUF
1 stop5h 55m
United Airlines
Deal found 5/2![United Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/2412:50 pm
BUF
- CHS
2 stops7h 20m
Southwest
jue. 5/284:45 pm
CHS
- BUF
1 stop6h 35m
Southwest
Deal found 5/4![Southwest logo]()
$262
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/95:00 am
BUF
- HHH
2 stops9h 13m
American Airlines
vie. 6/1211:40 am
HHH
- BUF
2 stops9h 43m
American Airlines
Deal found 5/1![American Airlines logo]()
$321
This JetBlue deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/87:45 am
BUF
- CHS
1 stop7h 19m
JetBlue
vie. 6/126:45 pm
CHS
- BUF
1 stop5h 03m
JetBlue
Deal found 5/3![JetBlue logo]()
$357
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/207:19 pm
BUF
- SAV
1 stop5h 02m
Delta
vie. 8/215:35 am
SAV
- BUF
1 stop5h 36m
Delta
Deal found 5/3![Delta logo]()
$251
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/217:19 pm
BUF
- SAV
1 stop5h 02m
Delta
mar. 8/255:35 am
SAV
- BUF
1 stop5h 36m
Delta
Deal found 5/2![Delta logo]()
$251
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/247:40 pm
BUF
- SAV
1 stop4h 24m
Delta
dom. 9/277:50 pm
SAV
- BUF
1 stop4h 08m
Delta
Deal found 5/1![Delta logo]()
$251
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/296:00 am
BUF
- CAE
2 stops8h 16m
United Airlines
lun. 6/12:29 pm
CAE
- BUF
1 stop6h 34m
United Airlines
Deal found 5/2![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/42:50 pm
BUF
- GSP
2 stops8h 00m
Southwest
mar. 6/161:50 pm
GSP
- BUF
1 stop8h 50m
Southwest
Deal found 5/3![Southwest logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/155:32 pm
BUF
- CAE
1 stop4h 13m
American Airlines
lun. 5/186:00 am
CAE
- BUF
1 stop5h 14m
American Airlines
Deal found 4/29![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/175:12 pm
BUF
- CHS
1 stop4h 54m
Delta
lun. 6/226:39 pm
CHS
- BUF
1 stop5h 24m
Delta
Deal found 5/2![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/106:00 am
BUF
- SAV
2 stops8h 16m
United Airlines
dom. 7/123:14 pm
SAV
- BUF
1 stop5h 27m
United Airlines
Deal found 4/29![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/61:15 pm
BUF
- CLT
1 stop4h 45m
Southwest
mar. 10/136:30 am
CLT
- BUF
1 stop7h 15m
Southwest
Deal found 5/3![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/1412:01 pm
BUF
- CHS
1 stop5h 57m
Delta
lun. 8/176:21 pm
CHS
- BUF
1 stop5h 08m
Delta
Deal found 5/3![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/27:00 am
BUF
- SAV
1 stop7h 16m
United Airlines
jue. 7/27:15 pm
SAV
- BUF
1 stop4h 44m
United Airlines
Deal found 4/30![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/87:35 am
BUF
- CHS
2 stops9h 45m
Southwest
vie. 6/121:55 pm
CHS
- BUF
2 stops10h 15m
Southwest
Deal found 5/4![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/67:00 am
BUF
- CHS
1 stop5h 12m
Delta
jue. 6/116:24 pm
CHS
- BUF
1 stop5h 35m
Delta
Deal found 4/30![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/2912:51 pm
BUF
- CAE
1 stop4h 47m
American Airlines
lun. 6/16:03 pm
CAE
- BUF
2 stops5h 53m
American Airlines
Deal found 4/29![American Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/97:00 am
BUF
- SAV
1 stop7h 16m
United Airlines
mié. 6/103:14 pm
SAV
- BUF
1 stop5h 49m
United Airlines
Deal found 5/3![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/21:10 pm
BUF
- CLT
2 stops7h 45m
Southwest
mar. 6/91:25 pm
CLT
- BUF
2 stops8h 00m
Southwest
Deal found 5/1![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/2110:54 am
BUF
- SAV
1 stop7h 25m
United Airlines
mar. 8/256:45 am
SAV
- BUF
2 stops7h 37m
United Airlines
Deal found 5/2![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/174:25 pm
BUF
- MYR
1 stop4h 45m
Southwest
dom. 6/217:25 am
MYR
- BUF
1 stop4h 20m
Southwest
Deal found 5/3![Southwest logo]()
$353
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/216:50 am
BUF
- HHH
1 stop4h 19m
American Airlines
sáb. 8/292:54 pm
HHH
- BUF
1 stop4h 10m
American Airlines
Deal found 5/3![American Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/147:00 am
BUF
- SAV
1 stop7h 11m
United Airlines
dom. 8/163:14 pm
SAV
- BUF
1 stop5h 54m
United Airlines
Deal found 5/3![United Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/96:03 am
BUF
- HHH
1 stop5h 28m
Delta
vie. 6/124:15 pm
HHH
- BUF
1 stop7h 17m
Delta
Deal found 5/1![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/206:05 am
BUF
- CHS
1 stop4h 55m
Southwest
dom. 5/247:05 am
CHS
- BUF
2 stops9h 50m
Southwest
Deal found 5/2![Southwest logo]()
$363
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/610:34 am
BUF
- CHS
2 stops11h 17m
United Airlines
jue. 6/1111:31 am
CHS
- BUF
1 stop5h 15m
United Airlines
Deal found 4/30![United Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/26:25 am
BUF
- CLT
1 stop5h 38m
Delta
mié. 9/96:00 am
CLT
- BUF
1 stop4h 35m
Delta
Deal found 4/29![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/246:02 am
BUF
- FLO
2 stops8h 08m
American Airlines
sáb. 6/272:35 pm
FLO
- BUF
1 stop4h 03m
American Airlines
Deal found 5/1![American Airlines logo]()
$478
Last-minute flights from Buffalo to South CarolinaDiscover last-minute flight deals from Buffalo to South Carolina. Data last updated mayo 4, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South Carolina. Data last updated mayo 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/177:44 pm
BUF
- CHS
2 stops36h 54m
Multiple Airlines
mar. 6/93:13 pm
CHS
- BUF
1 stop27h 59m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/197:39 pm
BUF
- SAV
1 stop4h 01m
Delta
sáb. 5/236:35 pm
SAV
- BUF
1 stop4h 19m
Delta
Deal found 4/29![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/194:55 pm
BUF
- CHS
1 stop6h 01m
Delta
mié. 6/106:22 pm
CHS
- BUF
1 stop5h 10m
Delta
Deal found 5/2![Delta logo]()
$267
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/256:25 am
BUF
- SAV
1 stop4h 06m
American Airlines
vie. 5/296:36 pm
SAV
- BUF
1 stop5h 18m
American Airlines
Deal found 5/1![American Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/267:31 pm
BUF
- SAV
1 stop4h 36m
American Airlines
sáb. 5/307:11 am
SAV
- BUF
1 stop4h 48m
American Airlines
Deal found 4/30![American Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/2612:18 pm
BUF
- GSP
1 stop3h 59m
Delta
mié. 6/36:35 pm
GSP
- BUF
1 stop5h 24m
Delta
Deal found 5/2![Delta logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/277:52 pm
BUF
- CHS
1 stop12h 46m
Multiple Airlines
lun. 6/19:28 pm
CHS
- BUF
2 stops40h 26m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/274:55 pm
BUF
- SAV
1 stop4h 56m
American Airlines
sáb. 5/307:11 am
SAV
- BUF
1 stop4h 48m
American Airlines
Deal found 4/30![American Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/288:49 pm
BUF
- MYR
1 stop12h 16m
Multiple Airlines
jue. 6/46:00 am
MYR
- BUF
2 stops31h 54m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/288:49 pm
BUF
- CHS
1 stop11h 56m
Multiple Airlines
jue. 6/47:25 am
CHS
- BUF
2 stops30h 29m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/297:52 pm
BUF
- CHS
1 stop12h 56m
Multiple Airlines
vie. 6/59:28 pm
CHS
- BUF
2 stops37h 13m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$256
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/294:55 pm
BUF
- CHS
1 stop6h 01m
Delta
lun. 6/16:38 pm
CHS
- BUF
1 stop5h 21m
Delta
Deal found 4/29![Delta logo]()
$257
One-way flights from Buffalo to South CarolinaSearch for one-way flight options from Buffalo to South Carolina. Find affordable one-way fares based on user searches. Data last updated mayo 4, 2026.
Search for one-way flight options from Buffalo to South Carolina. Find affordable one-way fares based on user searches. Data last updated mayo 4, 2026.
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/267:52 pm
BUF
- CLT
1 stop20h 51m
Frontier
Deal found 4/29![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/912:05 pm
BUF
- CLT
2 stops33h 30m
Frontier
Deal found 5/3![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/292:49 pm
BUF
- CLT
2 stops20h 45m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/237:52 pm
BUF
- CLT
1 stop16h 20m
Frontier
Deal found 4/29![Frontier logo]()
$101
This CheapOair deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/277:52 pm
BUF
- CLT
1 stop20h 51m
Frontier
Deal found 5/1![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/3012:41 pm
BUF
- CLT
2 stops10h 59m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$104
This CheapOair deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/289:02 pm
BUF
- CLT
1 stop19h 33m
Frontier
Deal found 5/2![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/242:50 pm
BUF
- CLT
2 stops21h 24m
Frontier
Deal found 4/30![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/267:52 pm
BUF
- CLT
1 stop21h 52m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/288:49 pm
BUF
- CLT
1 stop22h 03m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/237:52 pm
BUF
- CHS
1 stop12h 46m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/132:49 pm
BUF
- CLT
2 stops20h 45m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$115
Find flight deals from Buffalo to South Carolina
Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated mayo 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $221 (Kiwi.com) |
One-way from | $82 (CheapOair) |
Popular in | March |
Cheapest in | September |
Average price | $372 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 4, 2026.
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloSavannah
BUF - SAV
BUFSAV
Buffalo
mar. 10/13
4:30 pm-8:47 pm
1 stop4h 17m
Savannah/Hilton Head
jue. 10/15
6:50 pm-11:55 pm
1 stop5h 05m
$251
BuffaloSavannah
BUF - SAV
BUFSAV
Buffalo
jue. 8/20
7:19 pm-12:21 am
1 stop5h 02m
Savannah/Hilton Head
vie. 8/21
5:35 am-11:11 am
1 stop5h 36m
$251
BuffaloSavannah
BUF - SAV
BUFSAV
Buffalo
vie. 8/21
7:19 pm-12:21 am
1 stop5h 02m
Savannah/Hilton Head
mar. 8/25
5:35 am-11:11 am
1 stop5h 36m
$251
BuffaloSavannah
BUF - SAV
BUFSAV
Buffalo
jue. 9/24
7:40 pm-12:04 am
1 stop4h 24m
Savannah/Hilton Head
dom. 9/27
7:50 pm-11:58 pm
1 stop4h 08m
$251
BuffaloCharleston
BUF - CHS
BUFCHS
Buffalo
mié. 6/3
7:00 pm-11:52 pm
1 stop4h 52m
Charleston
mar. 6/9
3:08 pm-9:03 pm
1 stop5h 55m
$257
BuffaloCharleston
BUF - CHS
BUFCHS
Buffalo
mié. 6/17
5:12 pm-10:06 pm
1 stop4h 54m
Charleston
lun. 6/22
6:39 pm-12:03 am
1 stop5h 24m
$257
BuffaloCharleston
BUF - CHS
BUFCHS
Buffalo
vie. 8/14
12:01 pm-5:58 pm
1 stop5h 57m
Charleston
lun. 8/17
6:21 pm-11:29 pm
1 stop5h 08m
$257
BuffaloCharleston
BUF - CHS
BUFCHS
Buffalo
sáb. 6/6
7:00 am-12:12 pm
1 stop5h 12m
Charleston
jue. 6/11
6:24 pm-11:59 pm
1 stop5h 35m
$257
BuffaloCharleston
BUF - CHS
BUFCHS
Buffalo
dom. 5/24
12:50 pm-8:10 pm
2 stops7h 20m
Charleston
jue. 5/28
4:45 pm-11:20 pm
1 stop6h 35m
$262
BuffaloHilton Head Island
BUF - HHH
BUFHHH
Buffalo
mar. 6/9
6:03 am-11:31 am
1 stop5h 28m
Hilton Head Island
vie. 6/12
4:15 pm-11:32 pm
1 stop7h 17m
$311
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
BUF-SAV
BUF-CLT
BUF-MYR
BUF-CAE
BUF-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South Carolina
BUF-USSC
BUF-SAV
BUF-CLT
BUF-MYR
BUF-CAE
How far ahead should I book a flight from Buffalo to South Carolina?
The price you pay for your flight from Buffalo to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Buffalo to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $80). Flying from Buffalo to South Carolina in January is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated mayo 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Buffalo to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Buffalo to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South Carolina flights
Browse other Buffalo and South Carolina flight options. Last updated on mayo 4, 2026.
Popular flight searches
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Buffalo to South Carolina flights
Consider these flights traveling from Buffalo to South Carolina.
Top 5 airlines flying from Buffalo to South Carolina
Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$80 | Average$232 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$108 | Average$335 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$353 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$200 | Average$279 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$410 | FlexibilityNo cancel fee | On-time63% |