$136+ Cheap flights from Buffalo to Greenville (BUF - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Apr 4 — Apr 111
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Greenville
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Cheapest flights from Buffalo to GreenvilleExplore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:50 pm
BUF
- GSP
1 stop5h 08m
United Airlines
Tue 5/196:27 pm
GSP
- BUF
1 stop5h 06m
United Airlines
Deal found 3/3![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:25 am
BUF
- GSP
1 stop6h 55m
Southwest
Tue 5/1912:50 pm
GSP
- BUF
2 stops9h 25m
Southwest
Deal found 3/3![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:55 am
BUF
- GSP
1 stop4h 20m
American Airlines
Sat 4/46:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 3/4![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Tue 4/76:00 am
GSP
- BUF
1 stop5h 28m
American Airlines
Deal found 3/3![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:29 am
BUF
- GSP
1 stop4h 51m
American Airlines
Wed 4/87:48 pm
GSP
- BUF
1 stop4h 11m
American Airlines
Deal found 3/4![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:49 am
BUF
- GSP
1 stop5h 50m
American Airlines
Tue 5/266:14 am
GSP
- BUF
1 stop4h 19m
American Airlines
Deal found 3/1![American Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Sun 4/196:52 am
GSP
- BUF
1 stop4h 22m
American Airlines
Deal found 2/28![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:25 pm
BUF
- GSP
1 stop4h 21m
American Airlines
Mon 4/66:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 3/3![American Airlines logo]()
$337
Best flights from Buffalo to GreenvilleDiscover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
Discover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:55 am
BUF
- GSP
1 stop4h 20m
American Airlines
Sat 4/46:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 3/4![American Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
BUF
- GSP
1 stop7h 10m
United Airlines
Tue 5/56:27 pm
GSP
- BUF
1 stop5h 06m
United Airlines
Deal found 3/4![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:10 pm
BUF
- GSP
2 stops8h 30m
Southwest
Tue 5/261:55 pm
GSP
- BUF
1 stop8h 20m
Southwest
Deal found 3/1![Southwest logo]()
$370
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:02 am
BUF
- GSP
1 stop4h 57m
Delta
Wed 4/85:40 am
GSP
- BUF
1 stop5h 21m
Delta
Deal found 3/4![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:40 pm
BUF
- GSP
2 stops9h 35m
Southwest
Tue 4/2812:50 pm
GSP
- BUF
2 stops8h 55m
Southwest
Deal found 2/28![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:08 pm
BUF
- GSP
1 stop5h 46m
Delta
Sun 4/127:59 pm
GSP
- BUF
1 stop3h 55m
Delta
Deal found 2/28![Delta logo]()
$420
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:05 pm
BUF
- GSP
2 stops10h 40m
Southwest
Mon 3/2312:25 pm
GSP
- BUF
2 stops8h 05m
Southwest
Deal found 2/28![Southwest logo]()
$467
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:00 pm
BUF
- GSP
1 stop4h 29m
Delta
Wed 3/186:05 am
GSP
- BUF
1 stop8h 14m
Delta
Deal found 2/28![Delta logo]()
$511
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:10 am
BUF
- GSP
1 stop4h 05m
Southwest
Tue 3/1712:35 pm
GSP
- BUF
1 stop5h 45m
Southwest
Deal found 3/3![Southwest logo]()
$512
Last-minute flights from Buffalo to GreenvilleDiscover last-minute flight deals from Buffalo to Greenville. Data last updated March 5, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Greenville. Data last updated March 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:25 pm
BUF
- GSP
1 stop4h 21m
American Airlines
Mon 4/66:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 3/3![American Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:55 am
BUF
- GSP
1 stop4h 20m
American Airlines
Sat 4/46:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 3/4![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Tue 4/76:00 am
GSP
- BUF
1 stop5h 28m
American Airlines
Deal found 3/3![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:29 am
BUF
- GSP
1 stop4h 51m
American Airlines
Wed 4/87:48 pm
GSP
- BUF
1 stop4h 11m
American Airlines
Deal found 3/4![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Fri 4/106:00 am
GSP
- BUF
1 stop5h 14m
American Airlines
Deal found 3/3![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Sun 4/196:52 am
GSP
- BUF
1 stop4h 22m
American Airlines
Deal found 2/28![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Sun 4/266:52 am
GSP
- BUF
1 stop4h 22m
American Airlines
Deal found 2/28![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:28 pm
BUF
- GSP
1 stop4h 29m
American Airlines
Tue 4/2812:35 pm
GSP
- BUF
1 stop4h 07m
American Airlines
Deal found 2/28![American Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:00 pm
BUF
- GSP
1 stop4h 55m
Southwest
Tue 4/2812:50 pm
GSP
- BUF
2 stops8h 55m
Southwest
Deal found 2/28![Southwest logo]()
$372
One-way flights from Buffalo to GreenvilleSearch for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
Search for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:25 am
BUF
- GSP
1 stop6h 55m
Southwest
Deal found 3/3![Southwest logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:56 pm
BUF
- GSP
2 stops19h 52m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$140
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:59 pm
BUF
- GSP
1 stop5h 14m
Delta
Deal found 2/28![Delta logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:35 pm
BUF
- GSP
2 stops31h 03m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$155
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Deal found 3/3![American Airlines logo]()
$161
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:30 am
BUF
- GSP
2 stops8h 29m
United Airlines
Deal found 3/1![United Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:52 am
BUF
- GSP
1 stop8h 46m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$183
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:55 pm
BUF
- GSP
1 stop3h 55m
Southwest
Deal found 3/3![Southwest logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/51:02 pm
BUF
- GSP
2 stops31h 05m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:25 am
BUF
- GSP
2 stops10h 50m
Southwest
Deal found 3/3![Southwest logo]()
$189
Find flight deals from Buffalo to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (United Airlines) |
One-way from | $136 (Southwest) |
Popular in | September |
Cheapest in | June |
Average price | $355 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Tue 3/31
8:55 am-1:15 pm
1 stop4h 20m
Greenville
Sat 4/4
6:00 am-10:58 am
1 stop4h 58m
$286
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sat 5/2
7:00 am-2:10 pm
1 stop7h 10m
Greenville
Tue 5/5
6:27 pm-11:33 pm
1 stop5h 06m
$356
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Tue 5/19
1:10 pm-9:40 pm
2 stops8h 30m
Greenville
Tue 5/26
1:55 pm-10:15 pm
1 stop8h 20m
$370
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Fri 4/24
12:40 pm-10:15 pm
2 stops9h 35m
Greenville
Tue 4/28
12:50 pm-9:45 pm
2 stops8h 55m
$404
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Thu 4/2
6:02 am-10:59 am
1 stop4h 57m
Greenville
Wed 4/8
5:40 am-11:01 am
1 stop5h 21m
$415
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sat 4/11
6:08 pm-11:54 pm
1 stop5h 46m
Greenville
Sun 4/12
7:59 pm-11:54 pm
1 stop3h 55m
$420
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Mon 3/16
12:05 pm-10:45 pm
2 stops10h 40m
Greenville
Mon 3/23
12:25 pm-8:30 pm
2 stops8h 05m
$467
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Wed 3/11
1:00 pm-5:29 pm
1 stop4h 29m
Greenville
Wed 3/18
6:05 am-2:19 pm
1 stop8h 14m
$511
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Wed 3/11
9:10 am-1:15 pm
1 stop4h 05m
Greenville
Tue 3/17
12:35 pm-6:20 pm
1 stop5h 45m
$512
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Tue 4/21
9:25 am-4:20 pm
1 stop6h 55m
$136
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
BUF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Greenville
Prices
More
What’s the top layover airport for flights from Buffalo to Greenville?
Share of 1-stop round-trip flights from Buffalo to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Washington, D.C. (DCA) – chosen by Cheapflights users on 40% of 1-stop itineraries from Buffalo to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Buffalo to Greenville?
Average round-trip fare for 1-stop flights from Buffalo to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
New York (LGA) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Buffalo to Greenville?
Shortest average travel time for 1-stop one-way flights from Buffalo to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Washington, D.C. (DCA) have the shortest average one-way travel time for 1-stop routes: 4h 27m.
Which airport typically offers the quickest layover for flights from Buffalo to Greenville?
Average layover duration for 1-stop one-way flights from Buffalo to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (DCA) offer the fastest connection on this route, with an average layover time of 0h 51m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 5, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
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Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsSimpsonville
Duncan
Greer
Seneca
Anderson
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Top 3 airlines flying from Buffalo to Greenville
Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$277 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$296 | Average$362 | FlexibilityNo cancel fee | On-timeN/A |