$205+ Cheap flights from Islip, NY to Greenville (ISP - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Islip to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to Greenville
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Best
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One-way
Cheapest flights from Islip to GreenvilleExplore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:45 pm -
1 stop6h 45m
Tue 12/88:05 am -
1 stop8h 10m
Deal found 10/26![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:45 pm -
1 stop6h 45m
Thu 12/108:05 am -
1 stop8h 10m
Deal found 10/28![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:05 am -
1 stop4h 40m
Mon 11/238:50 pm -
2 stops11h 55m
Deal found 10/26![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:05 am -
1 stop3h 45m
Tue 12/228:05 pm -
1 stop3h 45m
Deal found 10/28![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:05 pm -
1 stop4h 30m
Mon 11/308:05 pm -
1 stop3h 45m
Deal found 10/25![Southwest logo]()
$428
Best flights from Islip to GreenvilleDiscover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:45 pm -
1 stop6h 45m
Thu 12/107:05 am -
2 stops8h 25m
Deal found 10/28![Southwest logo]()
$345
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:05 am -
1 stop3h 45m
Tue 12/228:05 pm -
1 stop3h 45m
Deal found 10/28![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:05 pm -
1 stop3h 50m
Mon 11/238:50 pm -
2 stops11h 55m
Deal found 10/28![Southwest logo]()
$410
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:55 am -
2 stops11h 35m
Tue 12/811:20 am -
2 stops10h 25m
Deal found 10/26![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:05 pm -
1 stop4h 30m
Mon 11/308:05 pm -
1 stop3h 45m
Deal found 10/25![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:25 pm -
2 stops7h 45m
Fri 11/131:00 pm -
1 stop4h 05m
Deal found 10/25![Southwest logo]()
$522
Last-minute flights from Islip to GreenvilleDiscover last-minute flight deals from Islip to Greenville. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to Greenville. Data last updated October 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 pm -
1 stop4h 05m
Fri 11/131:00 pm -
1 stop4h 05m
Deal found 10/25![Southwest logo]()
$517
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:05 am -
1 stop4h 40m
Mon 11/238:50 pm -
2 stops11h 55m
Deal found 10/26![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:05 pm -
1 stop4h 30m
Mon 11/308:05 pm -
1 stop3h 45m
Deal found 10/25![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 pm -
1 stop4h 05m
Mon 11/308:05 pm -
1 stop3h 45m
Deal found 10/25![Southwest logo]()
$497
One-way flights from Islip to GreenvilleSearch for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:30 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:02 pm -
2 stops17h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$225
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 pm -
1 stop4h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:02 pm -
3 stops40h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$376
This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:00 pm -
2 stops8h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Breeze Airways logo]()
$384
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:05 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$449
This KAYAK deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:13 pm -
2 stops15h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Breeze Airways logo]()
$485
Find flight deals from Islip to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $286 (Southwest) |
One-way from | $205 (Southwest) |
Popular in | May |
Cheapest in | March |
Average price | $473 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Fri 12/25
12:30 pm-7:55 pm
1 stop7h 25m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
Quickest round-trip
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Mon 11/23
5:40 pm-9:45 pm
1 stop4h 05m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sat 12/5
12:45 pm-7:30 pm
1 stop6h 45m
Greenville
Thu 12/10
7:05 am-3:30 pm
2 stops8h 25m
$345
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Fri 12/25
3:02 pm-7:53 am
3 stops40h 51m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$376
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Wed 11/18
12:00 pm-8:07 pm
2 stops8h 07m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$384
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sun 12/20
6:05 am-9:50 am
1 stop3h 45m
Greenville
Tue 12/22
8:05 pm-11:50 pm
1 stop3h 45m
$399
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Mon 11/23
4:40 pm-11:54 am
3 stops43h 14m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$407
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Mon 11/16
4:05 pm-7:55 pm
1 stop3h 50m
Greenville
Mon 11/23
8:50 pm-8:45 am
2 stops11h 55m
$410
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sat 12/5
7:55 am-7:30 pm
2 stops11h 35m
Greenville
Tue 12/8
11:20 am-9:45 pm
2 stops10h 25m
$418
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sat 11/21
5:05 pm-9:35 pm
1 stop4h 30m
Greenville
Mon 11/30
8:05 pm-11:50 pm
1 stop3h 45m
$428
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Islip to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Greenville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
ISP-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 30, 2026.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Islip and Greenville flights
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Other flights from Islip
Browse through other flights departing from Islip. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Islip to Greenville
Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$330 | Average$526 | FlexibilityNo cancel fee | On-time63% |