$219+ Cheap flights from Islip, NY to Greenville (ISP - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Islip to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to Greenville
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Best
Last-minute
One-way
Cheapest flights from Islip to GreenvilleExplore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:40 am -
2 stops11h 25m
Wed 10/211:25 pm -
1 stop6h 35m
Deal found 9/10![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
1 stop4h 35m
Sat 10/38:00 am -
1 stop8h 10m
Deal found 9/10![Southwest logo]()
$398
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:05 pm -
1 stop3h 45m
Sun 11/158:15 am -
1 stop3h 30m
Deal found 9/10![Southwest logo]()
$450
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:05 am -
1 stop3h 55m
Tue 1/58:05 am -
1 stop3h 40m
Deal found 9/10![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:40 pm -
1 stop3h 55m
Thu 10/158:25 am -
1 stop6h 05m
Deal found 9/13![Southwest logo]()
$478
Best flights from Islip to GreenvilleDiscover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:40 am -
2 stops11h 25m
Wed 10/211:25 pm -
1 stop6h 35m
Deal found 9/10![Southwest logo]()
$320
This KAYAK deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:00 pm -
2 stops33h 50m
Mon 9/288:32 pm -
2 stops16h 26m
Deal found 9/8![Breeze Airways logo]()
$683
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:05 pm -
1 stop3h 45m
Sun 11/156:40 am -
2 stops10h 25m
Deal found 9/10![Southwest logo]()
$477
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 pm -
1 stop4h 05m
Sun 11/158:15 am -
1 stop8h 50m
Deal found 9/11![Southwest logo]()
$509
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:05 am -
1 stop4h 10m
Fri 9/254:40 pm -
1 stop5h 30m
Deal found 9/9![Southwest logo]()
$572
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 pm -
1 stop3h 50m
Tue 10/61:25 pm -
1 stop6h 35m
Deal found 9/9![Southwest logo]()
$589
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:00 am -
2 stops9h 00m
Sun 10/257:15 am -
1 stop10h 20m
Deal found 9/12![Southwest logo]()
$714
Last-minute flights from Islip to GreenvilleDiscover last-minute flight deals from Islip to Greenville. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to Greenville. Data last updated September 14, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:05 am -
1 stop4h 10m
Fri 9/254:40 pm -
1 stop5h 30m
Deal found 9/9![Southwest logo]()
$572
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
1 stop4h 35m
Sat 10/38:00 am -
1 stop8h 10m
Deal found 9/10![Southwest logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:43 pm -
1 stop22h 04m
Tue 10/611:28 am -
2 stops23h 52m
Deal found 9/9![Multiple Airlines logo]()
$499
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:40 am -
2 stops11h 25m
Wed 10/211:25 pm -
1 stop6h 35m
Deal found 9/10![Southwest logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
1 stop18h 45m
Mon 10/128:32 pm -
2 stops16h 26m
Deal found 9/11![Multiple Airlines logo]()
$506
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:40 pm -
1 stop3h 55m
Thu 10/158:25 am -
1 stop6h 05m
Deal found 9/13![Southwest logo]()
$478
One-way flights from Islip to GreenvilleSearch for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:50 pm -
1 stop3h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:25 pm -
3 stops38h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:10 pm -
1 stop6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:33 pm -
2 stops41h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Breeze Airways logo]()
$387
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:00 pm -
2 stops7h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Breeze Airways logo]()
$394
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:00 pm -
2 stops31h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$395
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:28 pm -
2 stops25h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:02 pm -
3 stops42h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$406
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:02 pm -
2 stops24h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$415
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:00 pm -
2 stops31h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Breeze Airways logo]()
$440
Find flight deals from Islip to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $320 (Southwest) |
One-way from | $219 (Southwest) |
Popular in | May |
Cheapest in | March |
Average price | $726 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sat 10/10
3:50 pm-7:35 pm
1 stop3h 45m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$219
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Tue 10/6
9:40 am-9:05 pm
2 stops11h 25m
Greenville
Wed 10/21
1:25 pm-8:00 pm
1 stop6h 35m
$320
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Fri 10/9
3:10 pm-9:35 pm
1 stop6h 25m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Wed 10/21
12:00 pm-7:59 pm
2 stops31h 59m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$395
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sat 10/17
12:00 pm-7:44 pm
2 stops7h 44m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$404
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Mon 10/19
3:02 pm-3:29 pm
2 stops24h 27m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$415
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Tue 11/3
12:00 pm-7:44 pm
2 stops31h 44m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$420
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Wed 11/4
12:00 pm-8:15 am
3 stops44h 15m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$446
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Thu 10/22
10:57 am-7:59 pm
2 stops9h 02m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$454
IslipGreenville
ISP Islip Long Island - GSP Greenville
ISPGSP
Islip Long Island
Sun 11/1
7:45 pm-3:29 pm
3 stops43h 44m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$456
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Islip to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
ISP-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 14, 2026.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Islip and Greenville flights
Browse other Islip and Greenville flight options. Last updated on September 14, 2026.
Other flights from Islip
Browse through other flights departing from Islip. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Islip to Greenville
Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$302 | Average$516 | FlexibilityNo cancel fee | On-time63% |