$194+ Cheap flights from Islip, NY to Greenville (ISP - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Islip to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to Greenville
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Best
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Cheapest flights from Islip to GreenvilleExplore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:55 am
ISP
- GSP
1 stop4h 15m
Southwest
Wed 6/171:50 pm
GSP
- ISP
1 stop8h 45m
Southwest
Deal found 4/29![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:00 am
ISP
- GSP
1 stop4h 10m
Southwest
Sat 6/68:15 am
GSP
- ISP
1 stop3h 20m
Southwest
Deal found 4/28![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:35 am
ISP
- GSP
1 stop4h 40m
Southwest
Fri 6/51:55 pm
GSP
- ISP
1 stop9h 40m
Southwest
Deal found 4/28![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:10 pm
ISP
- GSP
1 stop3h 50m
Southwest
Tue 6/28:20 am
GSP
- ISP
1 stop3h 35m
Southwest
Deal found 4/28![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:40 pm
ISP
- GSP
1 stop3h 35m
Southwest
Thu 7/91:55 pm
GSP
- ISP
1 stop9h 40m
Southwest
Deal found 4/26![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:30 pm
ISP
- GSP
2 stops10h 05m
Southwest
Sat 5/305:25 pm
GSP
- ISP
2 stops5h 55m
Southwest
Deal found 4/27![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:05 pm
ISP
- GSP
2 stops7h 45m
Southwest
Mon 6/81:55 pm
GSP
- ISP
1 stop3h 20m
Southwest
Deal found 4/29![Southwest logo]()
$408
Best flights from Islip to GreenvilleDiscover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Islip to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:55 am
ISP
- GSP
2 stops10h 05m
Southwest
Wed 6/171:50 pm
GSP
- ISP
1 stop8h 45m
Southwest
Deal found 4/29![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:30 am
ISP
- GSP
2 stops9h 50m
Southwest
Sat 6/68:15 am
GSP
- ISP
1 stop6h 35m
Southwest
Deal found 4/28![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:35 am
ISP
- GSP
1 stop4h 40m
Southwest
Fri 6/51:55 pm
GSP
- ISP
1 stop9h 40m
Southwest
Deal found 4/30![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:10 am
ISP
- GSP
1 stop4h 05m
Southwest
Wed 6/171:50 pm
GSP
- ISP
1 stop8h 45m
Southwest
Deal found 4/30![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:30 pm
ISP
- GSP
2 stops10h 05m
Southwest
Sat 5/3012:25 pm
GSP
- ISP
1 stop3h 35m
Southwest
Deal found 4/27![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:40 pm
ISP
- GSP
1 stop3h 35m
Southwest
Thu 7/91:55 pm
GSP
- ISP
1 stop9h 40m
Southwest
Deal found 4/26![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:50 pm
ISP
- GSP
1 stop3h 45m
Southwest
Mon 6/81:55 pm
GSP
- ISP
1 stop3h 20m
Southwest
Deal found 4/29![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:35 pm
ISP
- GSP
1 stop3h 30m
Southwest
Mon 9/144:40 pm
GSP
- ISP
1 stop5h 25m
Southwest
Deal found 4/30![Southwest logo]()
$407
Last-minute flights from Islip to GreenvilleDiscover last-minute flight deals from Islip to Greenville. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to Greenville. Data last updated May 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:41 pm
ISP
- GSP
1 stop14h 14m
Breeze Airways
Mon 5/118:28 pm
GSP
- ISP
2 stops20h 19m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:57 am
ISP
- GSP
2 stops21h 58m
Multiple Airlines
Thu 5/142:18 pm
GSP
- ISP
1 stop27h 56m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:30 pm
ISP
- GSP
1 stop4h 25m
Southwest
Sat 6/68:15 am
GSP
- ISP
1 stop3h 20m
Southwest
Deal found 4/29![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:30 pm
ISP
- GSP
1 stop4h 25m
Southwest
Thu 6/48:30 am
GSP
- ISP
1 stop3h 20m
Southwest
Deal found 4/26![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:10 pm
ISP
- GSP
1 stop3h 50m
Southwest
Sun 5/247:35 am
GSP
- ISP
2 stops8h 30m
Southwest
Deal found 4/30![Southwest logo]()
$464
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:30 pm
ISP
- GSP
2 stops10h 05m
Southwest
Sun 5/247:35 am
GSP
- ISP
2 stops8h 30m
Southwest
Deal found 4/28![Southwest logo]()
$449
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:30 pm
ISP
- GSP
2 stops10h 05m
Southwest
Sat 5/3012:25 pm
GSP
- ISP
1 stop3h 35m
Southwest
Deal found 4/27![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:10 pm
ISP
- GSP
1 stop3h 50m
Southwest
Tue 6/28:20 am
GSP
- ISP
1 stop3h 35m
Southwest
Deal found 4/28![Southwest logo]()
$397
One-way flights from Islip to GreenvilleSearch for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Islip to Greenville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:50 pm
ISP
- GSP
1 stop3h 45m
Southwest
Deal found 4/29![Southwest logo]()
$194
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:45 pm
ISP
- GSP
1 stop3h 40m
Southwest
Deal found 4/27![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:28 pm
ISP
- GSP
3 stops46h 46m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:53 pm
ISP
- GSP
3 stops23h 55m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$305
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:41 pm
ISP
- GSP
1 stop14h 14m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$365
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:46 pm
ISP
- GSP
2 stops14h 32m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$460
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:49 pm
ISP
- GSP
3 stops23h 59m
Breeze Airways
Deal found 4/30![Breeze Airways logo]()
$461
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:53 pm
ISP
- GSP
3 stops23h 55m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$471
Find flight deals from Islip to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $368 (Southwest) |
One-way from | $194 (Southwest) |
Popular in | May |
Cheapest in | August |
Average price | $796 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Wed 6/10
8:55 am-7:00 pm
2 stops10h 05m
Greenville
Wed 6/17
1:50 pm-10:35 pm
1 stop8h 45m
$374
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Tue 6/2
6:30 am-4:20 pm
2 stops9h 50m
Greenville
Sat 6/6
8:15 am-2:50 pm
1 stop6h 35m
$388
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Mon 6/1
8:35 am-1:15 pm
1 stop4h 40m
Greenville
Fri 6/5
1:55 pm-11:35 pm
1 stop9h 40m
$392
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Fri 6/12
9:10 am-1:15 pm
1 stop4h 05m
Greenville
Wed 6/17
1:50 pm-10:35 pm
1 stop8h 45m
$392
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Mon 5/25
12:30 pm-10:35 pm
2 stops10h 05m
Greenville
Sat 5/30
12:25 pm-4:00 pm
1 stop3h 35m
$402
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Tue 7/7
4:40 pm-8:15 pm
1 stop3h 35m
Greenville
Thu 7/9
1:55 pm-11:35 pm
1 stop9h 40m
$402
Quickest round-trip
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Fri 6/5
5:50 pm-9:35 pm
1 stop3h 45m
Greenville
Mon 6/8
1:55 pm-5:15 pm
1 stop3h 20m
$402
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Fri 9/11
12:35 pm-4:05 pm
1 stop3h 30m
Greenville
Mon 9/14
4:40 pm-10:05 pm
1 stop5h 25m
$407
Cheapest one-way
Quickest one-way
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Fri 6/12
5:50 pm-9:35 pm
1 stop3h 45m
$194
IslipGreenville
ISP - GSP
ISPGSP
Islip Long Island
Sun 5/24
8:00 am-5:15 pm
2 stops9h 15m
$209
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Islip to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Greenville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Islip, New York-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Islip, New York-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Islip to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
ISP-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Islip to Greenville
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 1, 2026.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
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Islip and Greenville flights
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Browse through other flights departing from Islip. Flights are based on user searches made on Cheapflights and were last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Islip to Greenville
Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$286 | Average$402 | FlexibilityNo cancel fee | On-time63% |