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South Carolina

$51+ Cheap flights from Islip, NY (ISP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — CHS
Aug 28 — Sep 41
Fri 8/28
Fri 9/4
1 adult, Economy
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Cheap flight deals from Islip to South Carolina

Cheapest flights from Islip to South Carolina
Explore the most affordable flight options available from Islip to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Fri 9/117:05 am
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 7/27$117
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:39 am
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 9/147:05 am
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 7/24$121
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Mon 8/316:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/26$122
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Mon 8/316:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/25$127
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:33 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Wed 9/211:36 am
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/26$132
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:33 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Mon 8/316:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/26$137
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:33 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Thu 9/103:50 pm
CHS
-
ISP
1 stop3h 15m
Breeze Airways
Deal found 7/25$141
This CheapOair deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:33 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Mon 8/316:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/28$142
This CheapOair deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:45 pm
ISP
-
CHS
1 stop3h 31m
Breeze Airways
Mon 9/147:05 am
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 7/28$146
This CheapOair deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Fri 9/46:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 7/24$147
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:33 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Tue 9/88:00 am
CHS
-
ISP
1 stop3h 16m
Breeze Airways
Deal found 7/25$148
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:05 am
ISP
-
CLT
1 stop4h 10m
Southwest
Wed 9/168:30 am
CLT
-
ISP
1 stop3h 40m
Southwest
Deal found 7/28$177

Find flight deals from Islip to South Carolina

Keep the following information in mind while searching for Islip to South Carolina flight deals. Data was last updated July 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$112
(Kiwi.com)

One-way from

$51
(CheapOair)

Popular in

July

Cheapest in

January

Average price

$295

Good round-trip deal

$172 or less

Good one-way deal

$117 or less
Provider with most accurate pricing for New York (NYC)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Myrtle Beach Intl flights.
Search Deals
From Islip Long Island to South Carolina
Search Deals
One-way flight from Islip Long Island to South Carolina
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Islip Long Island to South Carolina.
Search Deals
Price to beat on a one-way flight from Islip Long Island to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Islip to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 10/16

9:39 am-11:51 am

Nonstop2h 12m

Charleston

Mon 10/19

7:05 am-8:59 am

Nonstop1h 54m

$163

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 8/26

6:05 am-10:15 am

1 stop4h 10m

Charlotte Douglas

Wed 9/2

8:30 am-12:10 pm

1 stop3h 40m

$177

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Thu 10/1

7:45 pm-11:16 pm

1 stop3h 31m

Charleston

Mon 10/5

7:05 am-8:59 am

Nonstop1h 54m

$181

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 9/9

6:05 am-10:15 am

1 stop4h 10m

Charlotte Douglas

Wed 9/16

12:35 pm-9:10 pm

2 stops8h 35m

$182

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Tue 10/13

6:05 am-9:55 am

1 stop3h 50m

Charlotte Douglas

Sat 10/17

11:35 am-9:45 pm

2 stops10h 10m

$182

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 10/2

9:39 am-11:51 am

Nonstop2h 12m

Charleston

Mon 10/5

7:05 am-8:59 am

Nonstop1h 54m

$203

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Sat 8/22

2:33 pm-4:41 pm

Nonstop2h 08m

Charleston

Sat 8/29

11:36 am-1:33 pm

Nonstop1h 57m

$208

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Mon 9/21

4:05 pm-8:45 pm

1 stop4h 40m

Charlotte Douglas

Fri 9/25

6:15 pm-10:10 pm

1 stop3h 55m

$215

IslipMyrtle Beach

ISP - MYR

ISPMYR

Islip Long Island

Thu 10/22

3:10 pm-9:25 pm

1 stop6h 15m

Myrtle Beach Intl

Mon 10/26

7:50 pm-11:35 pm

1 stop3h 45m

$217
Quickest round-trip

IslipMyrtle Beach

ISP - MYR

ISPMYR

Islip Long Island

Wed 10/21

6:08 pm-8:08 pm

Nonstop2h 00m

Myrtle Beach Intl

Mon 10/26

8:38 am-10:28 am

Nonstop1h 50m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Islip to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to South Carolina

What is the cheapest month to book a flight from Islip, New York to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $190). Flying from Islip, New York to South Carolina in March is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to SC?

Find hourly flight availability from Islip to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 44% on flights from Islip, New York to South Carolina by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Islip, New York to South Carolina?

Airfare is below average for this route at the moment.
Islip, New York to South Carolina flights typically cost between $158 and $260 in September.
The cheapest round-trip price found within the last 5 days was $112 on Breeze Airways (Sep 4-Sep 11).

How far ahead should I book a flight from Islip, New York to South Carolina?

The best time to book flights from Islip, New York to South Carolina is 43 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andFrontier from Islip to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
302 reviews

Entertainment

6.7

Overall

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Comfort

8.2

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Breeze Airways
8.2
Very good
302 reviews
Breeze Airways
8.2
Very good
302 reviews

Entertainment

6.7

Overall

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Comfort

8.2

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Southwest
8.0
Very good
4,228 reviews
Breeze Airways
8.2
Very good
302 reviews

Entertainment

6.7

Overall

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Comfort

8.2

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Frontier
5.6
Fair
2,749 reviews
Breeze Airways
8.2
Very good
302 reviews

Entertainment

6.7

Overall

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Comfort

8.2

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Related info for your journey

Find useful and relevant information for your journey from Islip to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to South Carolina?

    For a flight from Islip to South Carolina, you will be flying from Long Island. Islip Long Island (ISP) is just 7.2 mi from the center of the city.

  • How popular is this Islip, New York to South Carolina flight route?

    This flight path from Islip Long Island to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Islip, New York to South Carolina?

    Departing from Islip, New York to South Carolina will take you 2h 12m. There are 666 mi between Islip, New York and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Islip, New York to South Carolina one-way?

    $39 is the cheapest one-way deal found within the past few days, from Breeze Airways. You may also be able to find cheap deals on Frontier and Southwest, with prices starting from $64 and $100, respectively.

  • What are the most popular routes from Islip, New York to South Carolina?

    The most popular flight routes from Islip, New York to South Carolina are Islip Long Island - Myrtle Beach Intl, Islip Long Island - Charleston and Islip Long Island - Charlotte Douglas.

  • What are the cheapest flights from Islip, New York to South Carolina?

    On average you can expect to pay $209 for a flight from Islip, New York to South Carolina. The cheapest flight overall is $69 while the most popular route, (Islip Long Island - Myrtle Beach Intl) is currently priced at $128.

  • Can I find deals for flights from Islip to South Carolina that include hotel bookings?

    Yes. In addition to deals on Islip to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to South Carolina.

  • Can I find deals for business class flights from Islip to South Carolina?

    Yes. Cheapflights offers flight deals from Islip to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $190). Flying from Islip, New York to South Carolina in March is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Islip to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Islip to South Carolina

Discover the top 3 airlines that operate flights from Islip to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$94Average$216FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$118Average$229FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$266Average$452FlexibilityNo cancel feeOn-time63%

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