HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$34+ Cheap flights from Islip, NY (ISP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — CHS
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to South Carolina

Cheapest flights from Islip to South Carolina
Explore the most affordable flight options available from Islip to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Tue 5/192:47 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$74
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:55 am
ISP
-
MYR
Nonstop1h 57m
Frontier
Sat 5/2312:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$78
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Thu 6/412:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$80
This Priceline deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Tue 5/192:47 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/28$83
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Sat 5/3012:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$84
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Sun 5/3112:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$88
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:35 pm
ISP
-
MYR
Nonstop1h 53m
Frontier
Sun 6/1412:44 pm
MYR
-
ISP
Nonstop1h 48m
Frontier
Deal found 4/29$89
This Super.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Sat 5/2312:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/30$92
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Sat 5/2312:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/29$93
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:35 pm
ISP
-
MYR
Nonstop1h 48m
Multiple Airlines
Wed 9/93:33 pm
MYR
-
ISP
Nonstop1h 50m
Multiple Airlines
Deal found 4/27$95
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:25 pm
ISP
-
MYR
Nonstop1h 56m
Frontier
Sat 5/1612:44 pm
MYR
-
ISP
Nonstop1h 46m
Frontier
Deal found 4/30$98
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:39 am
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 9/147:05 am
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 4/29$107

Find flight deals from Islip to South Carolina

Keep the following information in mind while searching for Islip to South Carolina flight deals. Data was last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$74

One-way from

$34
(Super.com)

Popular in

April

Cheapest in

September

Average price

$265

Good round-trip deal

$157 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for New York (NYC)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Myrtle Beach Intl flights.
Search Deals
From Islip Long Island to South Carolina
Search Deals
One-way flight from Islip Long Island to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Islip Long Island to South Carolina.
Search Deals
Price to beat on a one-way flight from Islip Long Island to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Islip to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Mon 5/11

8:43 pm-10:51 pm

Nonstop2h 08m

Charleston

Wed 5/13

11:36 am-1:33 pm

Nonstop1h 57m

$133

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 10/2

9:39 am-11:51 am

Nonstop2h 12m

Charleston

Mon 10/5

7:05 am-8:59 am

Nonstop1h 54m

$198

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 5/29

8:43 pm-10:51 pm

Nonstop2h 08m

Charleston

Mon 6/1

6:06 pm-8:03 pm

Nonstop1h 57m

$223

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Fri 5/15

11:00 am-12:05 pm

1 stop25h 05m

Charlotte Douglas

Mon 5/18

7:58 pm-4:47 pm

2 stops20h 49m

$240

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Fri 5/15

11:00 am-12:05 pm

1 stop25h 05m

Charlotte Douglas

Sun 5/17

7:58 pm-10:05 am

1 stop14h 07m

$246

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Mon 5/11

2:28 pm-7:13 pm

2 stops28h 45m

Charlotte Douglas

Thu 5/14

7:57 pm-10:05 am

1 stop14h 08m

$246

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Thu 6/11

10:48 am-11:34 am

1 stop24h 46m

Charlotte Douglas

Mon 6/15

7:58 pm-6:38 pm

2 stops22h 40m

$278

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Thu 5/28

11:00 am-6:52 pm

1 stop7h 52m

Charlotte Douglas

Sun 5/31

7:57 pm-11:16 am

2 stops39h 19m

$297

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Fri 6/12

3:05 pm-9:40 pm

1 stop6h 35m

Charlotte Douglas

Mon 6/15

7:50 pm-11:35 pm

1 stop3h 45m

$299

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Mon 6/8

3:05 pm-9:40 pm

1 stop6h 35m

Charlotte Douglas

Mon 6/15

7:50 pm-11:35 pm

1 stop3h 45m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Islip to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to South Carolina

How far ahead should I book a flight from Islip, New York to South Carolina?

The best time to book flights from Islip, New York to South Carolina is 68 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Islip, New York to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $55). Flying from Islip, New York to South Carolina in March is currently the most expensive (average of $136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to SC?

Find hourly flight availability from Islip to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 29% on flights from Islip, New York to South Carolina by exploring options for tickets in the evening.

What is the cheapest day to fly from Islip, New York to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Islip to South Carolina. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their Islip, New York to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Islip, New York to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andFrontier from Islip to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
281 reviews

Entertainment

6.6

Crew

8.7

Comfort

8.2

Food

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Breeze Airways
8.1
Very good
281 reviews
Breeze Airways
8.1
Very good
281 reviews

Entertainment

6.6

Crew

8.7

Comfort

8.2

Food

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Southwest
8.0
Very good
4,317 reviews
Breeze Airways
8.1
Very good
281 reviews

Entertainment

6.6

Crew

8.7

Comfort

8.2

Food

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Frontier
5.7
Fair
2,970 reviews
Breeze Airways
8.1
Very good
281 reviews

Entertainment

6.6

Crew

8.7

Comfort

8.2

Food

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Related info for your journey

Find useful and relevant information for your journey from Islip to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to South Carolina?

    For a flight from Islip to South Carolina, you will be flying from Long Island. Islip Long Island (ISP) is just 7.2 mi from the center of the city.

  • How popular is this Islip, New York to South Carolina flight route?

    This flight path from Islip Long Island to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Islip, New York to South Carolina?

    Departing from Islip, New York to South Carolina will take you 2h 08m. There are 666 mi between Islip, New York and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Islip, New York to South Carolina one-way?

    $39 is the cheapest one-way deal found within the past few days, from Breeze Airways. You may also be able to find cheap deals on Frontier and Southwest, with prices starting from $63 and $119, respectively.

  • What are the most popular routes from Islip, New York to South Carolina?

    The most popular flight routes from Islip, New York to South Carolina are Islip Long Island - Charleston, Islip Long Island - Charlotte Douglas and Islip Long Island - Myrtle Beach Intl.

  • What are the cheapest flights from Islip, New York to South Carolina?

    On average you can expect to pay $223 for a flight from Islip, New York to South Carolina. The cheapest flight overall is $127 while the most popular route, (Islip Long Island - Charleston) is currently priced at $107.

  • Can I find deals for flights from Islip to South Carolina that include hotel bookings?

    Yes. In addition to deals on Islip to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to South Carolina.

  • Can I find deals for business class flights from Islip to South Carolina?

    Yes. Cheapflights offers flight deals from Islip to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $55). Flying from Islip, New York to South Carolina in March is currently the most expensive (average of $136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Islip to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San Francisco flights
Newark to San Francisco flights
LaGuardia to San Francisco flights
LaGuardia to Dallas/Fort Worth flights
LaGuardia to Miami flights
Newark to Dallas/Fort Worth flights
LaGuardia to Fort Lauderdale flights
Newark to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Las Vegas flights
Newark to Los Angeles flights
John F Kennedy Intl to Orlando flights
Newark to Las Vegas flights
John F Kennedy Intl to Dallas/Fort Worth flights
John F Kennedy Intl to Fort Lauderdale flights
LaGuardia to O'Hare Intl flights
Newark to Seattle flights
Newark to O'Hare Intl flights
John F Kennedy Intl to O'Hare Intl flights
Newark to Atlanta flights
Newark to Orlando flights
LaGuardia to Atlanta flights
LaGuardia to Orlando flights
LaGuardia to Los Angeles flights
LaGuardia to Las Vegas flights
Newark to Tampa flights
John F Kennedy Intl to Atlanta flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Denver flights
LaGuardia to Tampa flights
LaGuardia to Denver flights
John F Kennedy Intl to Sky Harbor Intl flights
John F Kennedy Intl to Tampa flights
Stewart to San Francisco flights
Newark to New Orleans flights
John F Kennedy Intl to Seattle flights
Newark to Hobby flights
LaGuardia to Hobby flights
Newark to Sky Harbor Intl flights
Newark to Denver flights
Newark to Austin flights
LaGuardia to New Orleans flights
Newark to West Palm Beach flights
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to San Jose flights
Newark to Charlotte flights
Newark to Nashville flights
LaGuardia to Nashville flights

Top 3 airlines flying from Islip to South Carolina

Discover the top 3 airlines that operate flights from Islip to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$190FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$108Average$225FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$271Average$434FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.