$74+ Cheap flights from Islip, NY (ISP) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — CHS
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Islip to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Islip to South Carolina
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Cheapest flights from Islip to South CarolinaExplore the most affordable flight options available from Islip to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Islip to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:39 am -
Nonstop2h 12m
Fri 11/207:05 am -
Nonstop1h 54m
Deal found 9/9![Breeze Airways logo]()
$148
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Fri 10/307:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$162
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 pm -
1 stop14h 12m
Sat 10/316:05 am -
1 stop11h 26m
Deal found 9/9![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:39 am -
Nonstop2h 12m
Thu 11/53:50 pm -
1 stop3h 15m
Deal found 9/9![Breeze Airways logo]()
$175
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:50 pm -
1 stop3h 55m
Sat 10/317:25 am -
1 stop4h 30m
Deal found 9/7![Southwest logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:39 am -
Nonstop2h 12m
Fri 10/307:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$177
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:45 pm -
1 stop3h 31m
Mon 11/167:05 am -
Nonstop1h 54m
Deal found 9/8![Breeze Airways logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/189:39 am -
Nonstop2h 12m
Mon 12/217:05 am -
Nonstop1h 54m
Deal found 9/8![Breeze Airways logo]()
$187
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:39 am -
Nonstop2h 12m
Mon 11/167:05 am -
Nonstop1h 54m
Deal found 9/8![Breeze Airways logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:08 pm -
Nonstop2h 00m
Wed 10/283:33 pm -
Nonstop1h 50m
Deal found 9/8![Breeze Airways logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:45 pm -
1 stop3h 31m
Mon 12/217:05 am -
Nonstop1h 54m
Deal found 9/9![Breeze Airways logo]()
$203
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Fri 10/237:05 am -
Nonstop1h 54m
Deal found 9/7![Breeze Airways logo]()
$204
Best flights from Islip to South CarolinaDiscover carefully curated flight deals from Islip to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Islip to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:08 pm -
Nonstop2h 00m
Sat 10/103:33 pm -
Nonstop1h 50m
Deal found 9/6![Breeze Airways logo]()
$248
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:25 pm -
1 stop14h 12m
Sun 10/189:42 pm -
1 stop20h 18m
Deal found 9/5![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:40 pm -
1 stop3h 50m
Fri 10/236:15 am -
1 stop8h 15m
Deal found 9/8![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
1 stop4h 00m
Tue 2/168:10 am -
1 stop3h 50m
Deal found 9/9![Southwest logo]()
$277
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:39 am -
Nonstop2h 12m
Mon 10/197:05 am -
Nonstop1h 54m
Deal found 9/10![Breeze Airways logo]()
$302
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:20 pm -
1 stop3h 55m
Sat 10/35:55 pm -
1 stop3h 50m
Deal found 9/8![Southwest logo]()
$277
This Breeze Airways deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:39 am -
Nonstop2h 12m
Mon 10/57:05 am -
Nonstop1h 54m
Deal found 9/6![Breeze Airways logo]()
$318
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:50 pm -
1 stop4h 35m
Sat 11/75:55 pm -
1 stop3h 50m
Deal found 9/6![Southwest logo]()
$309
This Breeze Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:45 pm -
1 stop3h 31m
Wed 9/307:00 am -
1 stop11h 28m
Deal found 9/9![Breeze Airways logo]()
$327
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:20 pm -
1 stop3h 55m
Mon 11/28:05 pm -
1 stop3h 25m
Deal found 9/6![Southwest logo]()
$309
This Breeze Airways deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:39 am -
Nonstop2h 12m
Fri 10/97:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$328
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:10 pm -
1 stop6h 20m
Mon 10/266:15 am -
1 stop8h 15m
Deal found 9/10![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:10 pm -
1 stop6h 25m
Tue 10/208:20 am -
1 stop3h 50m
Deal found 9/9![Southwest logo]()
$312
This United deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:30 pm -
2 stops28h 27m
Mon 10/267:54 pm -
2 stops15h 11m
Deal found 9/9![Multiple Airlines logo]()
$1,116
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:05 am -
1 stop3h 40m
Sat 10/245:55 pm -
1 stop3h 55m
Deal found 9/9![Southwest logo]()
$337
This Breeze Airways deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:39 am -
Nonstop2h 12m
Sun 10/183:50 pm -
1 stop3h 15m
Deal found 9/5![Breeze Airways logo]()
$408
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:25 pm -
1 stop5h 50m
Sun 11/87:45 am -
1 stop4h 00m
Deal found 9/7![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:25 pm -
1 stop9h 35m
Mon 11/91:40 pm -
2 stops9h 05m
Deal found 9/8![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:05 am -
2 stops10h 35m
Tue 10/206:10 pm -
1 stop4h 30m
Deal found 9/8![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:05 am -
1 stop4h 00m
Mon 11/231:40 pm -
1 stop3h 25m
Deal found 9/6![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:40 pm -
1 stop4h 20m
Thu 11/56:40 am -
2 stops10h 25m
Deal found 9/9![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:10 pm -
1 stop6h 20m
Thu 10/156:40 am -
2 stops10h 20m
Deal found 9/6![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:50 pm -
1 stop3h 25m
Sat 10/105:55 pm -
1 stop3h 55m
Deal found 9/10![Southwest logo]()
$372
This United deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:16 pm -
2 stops22h 19m
Mon 10/121:20 pm -
2 stops30h 25m
Deal found 9/5![Multiple Airlines logo]()
$1,305
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:35 am -
2 stops10h 15m
Mon 12/211:05 pm -
2 stops10h 30m
Deal found 9/9![Southwest logo]()
$379
This United deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:05 am -
2 stops31h 05m
Sun 9/271:16 pm -
2 stops30h 59m
Deal found 9/5![Multiple Airlines logo]()
$1,430
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:40 pm -
1 stop4h 05m
Mon 10/265:35 am -
2 stops8h 55m
Deal found 9/9![Southwest logo]()
$386
This United deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:05 am -
2 stops27h 30m
Mon 10/121:20 pm -
2 stops30h 25m
Deal found 9/6![Multiple Airlines logo]()
$1,438
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 pm -
1 stop4h 50m
Sun 11/17:30 am -
1 stop4h 15m
Deal found 9/7![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:25 pm -
2 stops9h 10m
Sun 12/138:05 pm -
1 stop3h 25m
Deal found 9/7![Southwest logo]()
$390
Last-minute flights from Islip to South CarolinaDiscover last-minute flight deals from Islip to South Carolina. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to South Carolina. Data last updated September 10, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:43 pm -
1 stop14h 52m
Sun 10/49:40 pm -
1 stop19h 18m
Deal found 9/9![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:45 pm -
1 stop3h 31m
Fri 10/237:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$215
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:55 pm -
1 stop13h 02m
Sun 10/189:32 am -
1 stop7h 58m
Deal found 9/9![Frontier logo]()
$209
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Fri 10/307:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$162
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Fri 10/237:05 am -
Nonstop1h 54m
Deal found 9/7![Breeze Airways logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Mon 10/267:05 am -
Nonstop1h 54m
Deal found 9/6![Breeze Airways logo]()
$207
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 pm -
1 stop14h 12m
Sat 10/316:05 am -
1 stop11h 26m
Deal found 9/9![Frontier logo]()
$168
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:50 pm -
1 stop3h 55m
Sat 10/317:25 am -
1 stop4h 30m
Deal found 9/7![Southwest logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:08 pm -
Nonstop2h 00m
Wed 10/283:33 pm -
Nonstop1h 50m
Deal found 9/8![Breeze Airways logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:08 pm -
Nonstop2h 00m
Sat 10/313:33 pm -
Nonstop1h 50m
Deal found 9/9![Breeze Airways logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:39 am -
Nonstop2h 12m
Fri 10/307:05 am -
Nonstop1h 54m
Deal found 9/5![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 pm -
1 stop3h 31m
Mon 11/27:05 am -
Nonstop1h 54m
Deal found 9/7![Breeze Airways logo]()
$208
One-way flights from Islip to South CarolinaSearch for one-way flight options from Islip to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Islip to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:08 pm -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$74
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:39 am -
Nonstop2h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Breeze Airways logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:08 pm -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Breeze Airways logo]()
$88
This Breeze Airways deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 pm -
1 stop3h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Breeze Airways logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:13 am -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Breeze Airways logo]()
$98
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:45 pm -
1 stop3h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Breeze Airways logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:38 pm -
2 stops19h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Breeze Airways logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/611:43 am -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Breeze Airways logo]()
$108
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:39 am -
Nonstop2h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Breeze Airways logo]()
$108
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:40 pm -
1 stop3h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Southwest logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:39 am -
Nonstop2h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Breeze Airways logo]()
$113
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:05 am -
2 stops11h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$114
Find flight deals from Islip to South Carolina
Keep the following information in mind while searching for Islip to South Carolina flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (CheapOair) |
One-way from | $74 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $279 |
Good round-trip deal | $208 or less |
Good one-way deal | $98 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Islip to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
IslipMyrtle Beach
ISP Islip Long Island - MYR Myrtle Beach Intl
ISPMYR
Islip Long Island
Sat 10/31
6:08 pm-8:08 pm
Nonstop2h 00m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$76
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Mon 11/30
9:39 am-11:51 am
Nonstop2h 12m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$86
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Thu 10/29
7:45 pm-11:16 pm
1 stop3h 31m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$96
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Tue 9/29
1:38 pm-8:38 am
2 stops19h 00m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$106
IslipMyrtle Beach
ISP Islip Long Island - MYR Myrtle Beach Intl
ISPMYR
Islip Long Island
Sat 11/7
12:45 pm-7:30 pm
1 stop6h 45m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$109
IslipMyrtle Beach
ISP Islip Long Island - MYR Myrtle Beach Intl
ISPMYR
Islip Long Island
Tue 12/8
6:05 am-10:05 am
1 stop4h 00m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$109
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Mon 10/26
9:39 am-11:51 am
Nonstop2h 12m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$113
IslipMyrtle Beach
ISP Islip Long Island - MYR Myrtle Beach Intl
ISPMYR
Islip Long Island
Tue 10/27
6:05 am-6:00 pm
2 stops11h 55m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$114
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Sun 10/11
7:45 pm-11:16 pm
1 stop3h 31m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$125
IslipCharleston
ISP Islip Long Island - CHS Charleston
ISPCHS
Islip Long Island
Thu 10/15
7:45 pm-11:16 pm
1 stop3h 31m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$125
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Islip to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Islip with our price prediction graph.
ISP-MYR
ISP-CHS
ISP-CLT
ISP-SAV
ISP-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Islip to South Carolina
ISP-USSC
ISP-MYR
ISP-CHS
ISP-CLT
ISP-SAV
What is the cheapest month to book a flight from Islip, New York to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $219). Flying from Islip, New York to South Carolina in March is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ISP to SC?
Find hourly flight availability from Islip to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 42% on flights from Islip, New York to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Islip, New York to South Carolina?
Airfare is below average for this route at the moment.
Islip, New York to South Carolina flights typically cost between $208 and $425 in January.The cheapest round-trip price found within the last 5 days was $122 on Breeze Airways (Jan 11-Jan 15).
How far ahead should I book a flight from Islip, New York to South Carolina?
The best time to book flights from Islip, New York to South Carolina is 43 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andFrontier from Islip to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.8
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.8
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.8
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Islip to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Islip to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Islip and South Carolina flights
Browse other Islip and South Carolina flight options. Last updated on September 10, 2026.
Popular flight searches
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Islip to South Carolina flights
Consider these flights traveling from Islip to South Carolina.
Top 3 airlines flying from Islip to South Carolina
Discover the top 3 airlines that operate flights from Islip to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$94 | Average$239 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$250 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$240 | Average$450 | FlexibilityNo cancel fee | On-time63% |