HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$89+ Cheap flights from South Carolina to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BUF
Jul 24 — Jul 311
Fri 7/24
Fri 7/31
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Buffalo

Cheapest flights from South Carolina to Buffalo
Explore the most affordable flight options available from South Carolina to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:58 am
CHS
-
BUF
1 stop8h 12m
JetBlue
Wed 8/196:00 am
BUF
-
CHS
1 stop6h 15m
JetBlue
Deal found 6/22$202
This Frontier deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Wed 8/127:57 pm
BUF
-
CLT
1 stop11h 54m
Frontier
Deal found 6/23$210
This JetBlue deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:51 pm
SAV
-
BUF
1 stop5h 22m
JetBlue
Wed 7/299:15 am
BUF
-
SAV
1 stop8h 40m
JetBlue
Deal found 6/23$217
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Wed 8/57:57 pm
BUF
-
CLT
1 stop11h 54m
Frontier
Deal found 6/22$220
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Sat 8/810:02 pm
BUF
-
CLT
1 stop9h 49m
Frontier
Deal found 6/22$225
This Priceline deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:58 am
CHS
-
BUF
1 stop7h 58m
JetBlue
Sat 7/1110:43 am
BUF
-
CHS
1 stop6h 19m
JetBlue
Deal found 6/21$226
This JetBlue deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:42 pm
CHS
-
BUF
1 stop4h 50m
JetBlue
Wed 9/210:25 am
BUF
-
CHS
1 stop7h 21m
JetBlue
Deal found 6/19$227
This Super.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Tue 7/289:09 pm
BUF
-
CLT
1 stop19h 49m
Frontier
Deal found 6/23$232
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Thu 8/139:33 pm
BUF
-
CLT
1 stop10h 18m
Frontier
Deal found 6/22$234
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:36 am
CLT
-
BUF
1 stop7h 56m
Frontier
Tue 8/189:29 pm
BUF
-
CLT
1 stop10h 32m
Frontier
Deal found 6/19$235
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Sun 8/99:33 pm
BUF
-
CLT
1 stop10h 18m
Frontier
Deal found 6/22$240
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:24 pm
CLT
-
BUF
1 stop6h 42m
Frontier
Thu 8/69:33 pm
BUF
-
CLT
1 stop10h 18m
Frontier
Deal found 6/22$245

Find flight deals from South Carolina to Buffalo

Keep the following information in mind while searching for South Carolina to Buffalo flight deals. Data was last updated June 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$202
(JetBlue)

One-way from

$89
(JetBlue)

Popular in

March

Cheapest in

September

Average price

$446
Provider with most accurate pricing for Myrtle Beach Intl-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Buffalo flights.
Search Deals
From South Carolina to Buffalo
Search Deals
One-way flight from South Carolina to Buffalo
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from South Carolina to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 7/8

10:58 am-6:56 pm

1 stop7h 58m

Buffalo

Wed 7/15

6:00 am-12:15 pm

1 stop6h 15m

$202

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Wed 7/22

6:51 pm-12:13 am

1 stop5h 22m

Buffalo

Wed 7/29

9:15 am-5:55 pm

1 stop8h 40m

$217

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Fri 7/24

10:58 am-6:26 pm

1 stop7h 28m

Buffalo

Mon 7/27

7:00 am-12:15 pm

1 stop5h 15m

$226

ColumbiaBuffalo

CAE - BUF

CAEBUF

Columbia Metropolitan

Sat 7/18

5:55 pm-11:42 pm

1 stop5h 47m

Buffalo

Wed 7/22

10:21 am-3:22 pm

1 stop5h 01m

$261

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Fri 9/4

6:45 pm-11:59 pm

1 stop5h 14m

Buffalo

Mon 9/7

6:05 am-10:08 am

1 stop4h 03m

$267

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Fri 9/18

5:33 pm-11:54 pm

1 stop6h 21m

Buffalo

Sun 9/20

6:05 am-10:06 am

1 stop4h 01m

$267

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 9/2

1:25 pm-5:45 pm

1 stop4h 20m

Buffalo

Sat 9/5

5:45 am-4:40 pm

2 stops10h 55m

$272

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Tue 9/15

7:35 am-2:20 pm

2 stops6h 45m

Buffalo

Tue 9/29

6:00 am-10:05 am

1 stop4h 05m

$272

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 8/18

8:49 am-3:06 pm

1 stop6h 17m

Buffalo

Tue 8/25

6:27 am-10:15 am

1 stop3h 48m

$303

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Tue 8/18

11:00 am-8:35 pm

2 stops9h 35m

Buffalo

Tue 8/25

8:55 am-1:50 pm

1 stop4h 55m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/21

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from South Carolina to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Buffalo

What is the cheapest month to book a flight from South Carolina to Buffalo?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $76). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $241). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Buffalo?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from South Carolina?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from South Carolina. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • How long is the flight from South Carolina to Buffalo?

    Departing from South Carolina to Buffalo will take you 5h 47m. The distance from South Carolina to Buffalo is about 634 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Buffalo one-way?

    $87 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on JetBlue and American Airlines, with prices starting from $88 and $99, respectively.

  • What are the most popular routes from South Carolina to Buffalo?

    The most popular flight routes from South Carolina to Buffalo are Charlotte Douglas - Buffalo, Columbia Metropolitan - Buffalo and Greenville - Buffalo.

  • Can I find deals for flights from South Carolina to Buffalo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Buffalo.

  • Can I find deals for business class flights from South Carolina to Buffalo?

    Yes. Cheapflights offers flight deals from South Carolina to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Buffalo?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $76). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $241). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Amherst
Batavia
Williamsville
Orchard Park
Eden

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
San Francisco to Newark flights
San Francisco to John F Kennedy Intl flights
San Francisco to LaGuardia flights
Dallas/Fort Worth to LaGuardia flights
Los Angeles to John F Kennedy Intl flights
Los Angeles to Newark flights
Dallas/Fort Worth to Newark flights
Dallas/Fort Worth to John F Kennedy Intl flights
Seattle to Newark flights
O'Hare Intl to John F Kennedy Intl flights
Ontario to John F Kennedy Intl flights
Los Angeles to LaGuardia flights
Hobby to LaGuardia flights
Seattle to John F Kennedy Intl flights
Miami to Newark flights
O'Hare Intl to Newark flights
Atlanta to John F Kennedy Intl flights
O'Hare Intl to LaGuardia flights
Orlando to Newark flights
Orlando to LaGuardia flights
Atlanta to Newark flights
Atlanta to LaGuardia flights
Miami to LaGuardia flights
Hobby to Newark flights
Fort Lauderdale to Newark flights
San Jose to Newark flights
Miami to John F Kennedy Intl flights
Tampa to Newark flights
Fort Lauderdale to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Austin to Newark flights
George Bush Intcntl to LaGuardia flights
Denver to Newark flights
San Jose to John F Kennedy Intl flights
Hobby to John F Kennedy Intl flights
George Bush Intcntl to Newark flights
Denver to LaGuardia flights
Orlando to John F Kennedy Intl flights
Oakland to John F Kennedy Intl flights
Austin to John F Kennedy Intl flights
Detroit to Newark flights
Detroit to LaGuardia flights
Seattle to LaGuardia flights
Detroit to John F Kennedy Intl flights
George Bush Intcntl to John F Kennedy Intl flights
Tampa to John F Kennedy Intl flights
Charlotte to Newark flights
Denver to John F Kennedy Intl flights
West Palm Beach to John F Kennedy Intl flights

Top 4 airlines flying from South Carolina to Buffalo

Discover the top 4 airlines that operate flights from South Carolina to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$76Average$189FlexibilityNo cancel feeOn-time62%
DeltaCheapest$118Average$340FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$195Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$442FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.