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$239+ Cheap flights from San Diego to Florence, SC (SAN - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — FLO
May 17 — May 241
Sat 5/17
Sat 5/24
1 adult, Economy
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Cheap flight deals from San Diego to Florence

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2025.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$417
(American Airlines)

One-way from

$239
(American Airlines)
Provider with most accurate pricing for San Diego-Florence flight deals.
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Provider most trusted by Cheapflights users for San Diego-Florence flights.
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One-way flight from San Diego to Florence
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Find flight deals from San Diego to Florence

Cheapest flights from San Diego to Florence
Explore the most affordable flight options available from San Diego to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2025.

This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/101:23 pmSAN - FLO
1 stop7h 36mAmerican Airlines
Sat 7/125:07 amFLO - SAN
1 stop6h 57mAmerican Airlines
Deal found 5/11$417

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2025.
Use the filters below to find and compare flights from San Diego to Florence that are best for you.

Fly from

San Diego

Fly to

Florence

Route

Depart

Return

Price

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Thu 7/10

1:23 pm-11:59 pm

1 stop7h 36m

Florence

Sat 7/12

5:07 am-9:04 am

1 stop6h 57m

$417

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Mon 6/9

11:32 am-11:56 pm

1 stop9h 24m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/11

  • Most accurate provider: When it comes to deals on San Diego-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on San Diego-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from San Diego-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Florence

What is the cheapest month to book a flight from San Diego to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from San Diego to Florence, South Carolina (average of $366). Flying from San Diego to Florence, South Carolina in June is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to FLO?

Find hourly flight availability from San Diego to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 12, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 35% on flights from San Diego to Florence, South Carolina by exploring options for tickets at noon.

Rainfall in Florence by month

Plan your trip to Florence by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

Temperature in Florence by month

Plan your trip to Florence by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated May 12, 2025.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Overall

7.2

Crew

8.0

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Overall

7.2

Crew

8.0

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from San Diego to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from San Diego to Florence, South Carolina round-trip?

    Cheapflights users have booked flights from San Diego to Florence, South Carolina round-trip from $417.

  • Can I find deals for flights from San Diego to Florence that include hotel bookings?

    Yes. In addition to deals on San Diego to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Florence.

  • Can I find deals for business class flights from San Diego to Florence?

    Yes. Cheapflights offers flight deals from San Diego to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from San Diego to Florence, South Carolina (average of $366). Flying from San Diego to Florence, South Carolina in June is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

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Top airline flying from San Diego to Florence

Discover the top airline that operate flights from San Diego to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$590FlexibilityNo cancel feeOn-time71%

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