HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$299+ Cheap flights from Massachusetts to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — FLO
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Massachusetts to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Massachusetts to Florence

Cheapest flights from Massachusetts to Florence
Explore the most affordable flight options available from Massachusetts to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:05 amBDL - FLO
1 stop6h 21mAmerican Airlines
Wed 1/145:36 pmFLO - BDL
1 stop6h 08mAmerican Airlines
Deal found 12/28$469
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:50 amBDL - FLO
1 stop4h 36mAmerican Airlines
Sun 1/116:15 amFLO - BDL
1 stop6h 17mAmerican Airlines
Deal found 12/29$526
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:19 pmBDL - FLO
2 stops6h 56mAmerican Airlines
Wed 1/146:15 amFLO - BDL
1 stop6h 17mAmerican Airlines
Deal found 12/28$559
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:19 pmBDL - FLO
2 stops6h 56mAmerican Airlines
Sun 1/115:36 pmFLO - BDL
1 stop6h 11mAmerican Airlines
Deal found 12/29$593
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:50 amBOS - FLO
2 stops8h 15mAmerican Airlines
Thu 1/85:36 pmFLO - BOS
1 stop6h 15mAmerican Airlines
Deal found 12/28$951

Find flight deals from Massachusetts to Florence

Keep the following information in mind while searching for Massachusetts to Florence flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(American Airlines)

Popular in

April

Cheapest in

March

Average price

$516
Provider with most accurate pricing for Boston Logan Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Florence flights.
Search Deals
From Massachusetts to Florence
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Massachusetts to Florence that are best for you.

Fly from

Massachusetts

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 1/27

12:21 pm-5:09 pm

1 stop4h 48m

Florence

Tue 2/3

5:36 pm-10:22 pm

1 stop4h 46m

$299

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 1/13

6:23 pm-10:43 pm

1 stop4h 20m

Florence

Sat 1/17

5:36 pm-10:22 pm

1 stop4h 46m

$339

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/19

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Mon 3/23

6:20 pm-10:51 pm

1 stop4h 31m

$439

HartfordFlorence

BDL - FLO

BDLFLO

Hartford Bradley Intl

Mon 1/12

4:14 pm-10:43 pm

1 stop6h 29m

Florence

Thu 1/15

6:15 am-12:32 pm

1 stop6h 17m

$805

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Tue 1/6

2:18 pm-10:43 pm

2 stops8h 25m

$342

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Wed 1/7

2:18 pm-10:43 pm

2 stops8h 25m

$342

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Mon 1/5

1:45 pm-12:15 am

2 stops10h 30m

$363

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Thu 1/8

2:18 pm-10:43 pm

2 stops8h 25m

$363

HartfordFlorence

BDL - FLO

BDLFLO

Hartford Bradley Intl

Tue 1/6

4:14 pm-10:43 pm

1 stop6h 29m

$373

HartfordFlorence

BDL - FLO

BDLFLO

Hartford Bradley Intl

Wed 1/7

4:14 pm-10:43 pm

1 stop6h 29m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 14 results
1
2

Best time to book a flight from Massachusetts to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Florence

What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

Currently, February is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $63). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Massachusetts?

    For a flight from Massachusetts to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Massachusetts to Florence, South Carolina?

    A quick flight from Massachusetts to Florence, South Carolina can take about 4h 48m. American Airlines provides one of the quickest options available for as low as $299. The distance between Massachusetts and Florence, South Carolina is about 735 mi.

  • What are the most popular routes from Massachusetts to Florence, South Carolina?

    The most popular flight routes from Massachusetts to Florence, South Carolina are Hartford Bradley Intl - Florence, Boston Logan Intl - Florence and Albany Intl - Florence.

  • Can I find deals for flights from Massachusetts to Florence that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Florence.

  • Can I find deals for business class flights from Massachusetts to Florence?

    Yes. Cheapflights offers flight deals from Massachusetts to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $63). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Massachusetts to Florence

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to Charleston flights
Boston to Charleston flights
Newark to Charlotte flights
Newark to Charleston flights
Boston to Charlotte flights
O'Hare Intl to Charleston flights
O'Hare Intl to Charlotte flights
Denver to Charlotte flights
LaGuardia to Charlotte flights
Dallas/Fort Worth to Charlotte flights
LaGuardia to Charleston flights
Minneapolis to Charleston flights
Dulles Intl to Charlotte flights
Boston to Savannah flights
Dulles Intl to Charleston flights
John F Kennedy Intl to Savannah flights
Newark to Savannah flights
Boston to Myrtle Beach flights
O'Hare Intl to Savannah flights
Newark to Myrtle Beach flights
Baltimore to Charleston flights
Baltimore to Charlotte flights
Detroit to Charleston flights
Philadelphia to Charleston flights
LaGuardia to Myrtle Beach flights
Reagan-National to Charleston flights
Minneapolis to Charlotte flights
LaGuardia to Savannah flights
Detroit to Charlotte flights
John F Kennedy Intl to Myrtle Beach flights
Hobby to Charlotte flights
Fort Lauderdale to Charlotte flights
Denver to Charleston flights
Seattle to Charlotte flights
Baltimore to Myrtle Beach flights
Minneapolis to Savannah flights
Denver to Savannah flights
White Plains to Charleston flights
Philadelphia to Myrtle Beach flights
Dulles Intl to Savannah flights
Philadelphia to Charlotte flights
Detroit to Savannah flights
George Bush Intcntl to Charlotte flights
Philadelphia to Savannah flights
Newark to Greenville flights
Miami to Charlotte flights
Providence to Charleston flights
Los Angeles to Charlotte flights
Detroit to Myrtle Beach flights

Top airline flying from Massachusetts to Florence

Discover the top airline that operate flights from Massachusetts to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$330Average$463FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.