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Durham

$55+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$130
(Expedia)

One-way from

$55
(Priceline)

Popular in

June

Cheapest in

August

Average price

$404
Provider with most accurate pricing for Jackson-Evers Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Raleigh-Durham flights.
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From Mississippi to Durham
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One-way flight from Mississippi to Durham
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Highest demand for flights based on searches. 18% potential increase in price ($86 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Expedia deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/41:11 pmMEM - RDU
1 stop10h 01mFrontier
jue. 12/116:00 amRDU - MEM
1 stop7h 06mFrontier
Deal found 11/6$130
This Breeze Airways deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1212:10 pmMEM - RDU
Nonstop1h 53mBreeze Airways
lun. 12/1510:26 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 11/6$158
This Priceline deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/112:10 pmMEM - RDU
Nonstop1h 53mMultiple Airlines
jue. 12/46:00 amRDU - MEM
1 stop7h 06mMultiple Airlines
Deal found 11/6$167
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/65:05 amMEM - RDU
1 stop4h 22mAmerican Airlines
sáb. 12/61:27 pmRDU - MEM
1 stop5h 25mAmerican Airlines
Deal found 11/6$171
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/65:05 amMEM - RDU
1 stop6h 27mAmerican Airlines
sáb. 12/133:01 pmRDU - MEM
1 stop5h 42mAmerican Airlines
Deal found 11/6$177
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1212:10 pmMEM - RDU
Nonstop1h 53mMultiple Airlines
lun. 12/155:50 pmRDU - MEM
1 stop19h 42mMultiple Airlines
Deal found 11/6$179
This Expedia deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1712:10 pmMEM - RDU
Nonstop1h 53mMultiple Airlines
jue. 11/206:00 amRDU - MEM
1 stop9h 32mMultiple Airlines
Deal found 11/5$180
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:26 pmMEM - RDU
1 stop16h 42mMultiple Airlines
mar. 12/98:14 pmRDU - MEM
1 stop23h 33mMultiple Airlines
Deal found 11/6$211
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/255:55 pmGPT - RDU
1 stop14h 02mMultiple Airlines
mié. 12/38:14 pmRDU - GPT
1 stop24h 01mMultiple Airlines
Deal found 11/5$220
This Breeze Airways deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/2612:10 pmMEM - RDU
Nonstop1h 53mBreeze Airways
lun. 12/2910:26 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 11/5$228
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/86:51 pmGPT - RDU
2 stops28h 21mMultiple Airlines
dom. 12/147:22 pmRDU - GPT
1 stop14h 37mMultiple Airlines
Deal found 11/6$231
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:00 amBTR - RDU
1 stop6h 07mDelta
mié. 12/36:00 pmRDU - BTR
1 stop4h 53mDelta
Deal found 11/4$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

sáb. 12/6

5:05 am-12:32 pm

1 stop6h 27m

Raleigh-Durham

sáb. 12/13

3:01 pm-7:43 pm

1 stop5h 42m

$177

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

jue. 12/4

8:26 pm-2:08 pm

1 stop16h 42m

Raleigh-Durham

mar. 12/9

8:14 pm-6:47 pm

1 stop23h 33m

$211

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

vie. 12/26

12:10 pm-3:03 pm

Nonstop1h 53m

Raleigh-Durham

lun. 12/29

10:26 am-11:30 am

Nonstop2h 04m

$218

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

mar. 11/25

5:55 pm-8:57 am

1 stop14h 02m

Raleigh-Durham

mié. 12/3

8:14 pm-7:15 pm

1 stop24h 01m

$220

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

jue. 11/27

2:21 pm-6:58 pm

1 stop3h 37m

Raleigh-Durham

mié. 12/3

2:12 pm-7:57 pm

1 stop6h 45m

$249

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

lun. 11/24

6:55 pm-12:20 am

1 stop4h 25m

Raleigh-Durham

mar. 12/2

2:12 pm-7:57 pm

1 stop6h 45m

$249

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

jue. 11/27

10:30 am-4:53 pm

1 stop5h 23m

Raleigh-Durham

mar. 12/2

2:12 pm-7:57 pm

1 stop6h 45m

$249

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

vie. 12/5

6:59 pm-12:18 am

1 stop4h 19m

Raleigh-Durham

dom. 12/7

5:15 am-9:43 am

1 stop5h 28m

$249

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

mar. 12/9

2:53 pm-7:16 pm

1 stop3h 23m

Raleigh-Durham

dom. 12/14

5:15 am-9:50 am

1 stop5h 35m

$249

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

sáb. 12/6

7:15 am-7:15 pm

2 stops11h 00m

Raleigh-Durham

sáb. 12/13

7:55 am-7:15 pm

1 stop12h 20m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $185). Flying from Mississippi to Durham in October is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

When flying from Mississippi to Durham, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 21% versus a flight in the morning.

How much does it cost to fly round-trip from Mississippi to Durham?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Durham?

    There are many flights that can get you from Mississippi to Durham in 1h 53m. Fly via American Airlines, Breeze Airways, or Delta to get the fastest option. The distance from Mississippi to Durham is about 632 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $59. United Airlines flights start at $125 while deals on Delta start at $125 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Memphis - Raleigh-Durham. You may also consider Baton Rouge Ryan - Raleigh-Durham or Alexandria - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $185). Flying from Mississippi to Durham in October is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$394FlexibilityNo cancel feeOn-time71%
DeltaCheapest$226Average$352FlexibilityNo cancel feeOn-timeN/A

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