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Durham

$49+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Jul 30 — Aug 61
Wed 7/30
Wed 8/6
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated July 25, 2025.

Round-trip from

$98
(Breeze Airways)

One-way from

$49
(Breeze Airways)

Popular in

October

Cheapest in

September

Average price

$436
From Mississippi to Durham
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One-way flight from Mississippi to Durham
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2025.

This Breeze Airways deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2210:23 amMEM - RDU
Nonstop2h 05mBreeze Airways
Mon 8/258:33 amRDU - MEM
Nonstop2h 10mBreeze Airways
Deal found 7/23$98
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:35 pmMEM - RDU
2 stops17h 00mSpirit Airlines
Sun 9/2810:40 amRDU - MEM
1 stop5h 46mSpirit Airlines
Deal found 7/24$220
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:30 amMEM - RDU
1 stop4h 17mDelta
Tue 9/168:50 amRDU - MEM
1 stop5h 24mDelta
Deal found 7/23$237
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/198:30 amMEM - RDU
2 stops7h 50mSouthwest
Sat 8/236:25 amRDU - MEM
1 stop4h 45mSouthwest
Deal found 7/23$242
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:56 pmMEM - RDU
1 stop20h 32mFrontier
Sun 9/286:52 pmRDU - MEM
1 stop23h 40mFrontier
Deal found 7/23$245
This FlightHub deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1510:23 amMEM - RDU
Nonstop2h 05mMultiple Airlines
Sun 8/179:27 amRDU - MEM
1 stop7h 37mMultiple Airlines
Deal found 7/24$247
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/239:12 amMOB - RDU
1 stop3h 49mDelta
Thu 8/285:20 amRDU - MOB
1 stop4h 12mDelta
Deal found 7/21$249
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:15 amBTR - RDU
1 stop6h 47mAmerican Airlines
Thu 8/215:25 amRDU - BTR
1 stop5h 50mAmerican Airlines
Deal found 7/23$249
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/198:00 amMOB - RDU
1 stop5h 10mUnited Airlines
Tue 8/2611:23 amRDU - MOB
2 stops9h 08mUnited Airlines
Deal found 7/21$254
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/215:10 amJAN - RDU
1 stop4h 15mAmerican Airlines
Sun 8/248:19 pmRDU - JAN
1 stop4h 37mAmerican Airlines
Deal found 7/24$260
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1512:00 pmJAN - RDU
1 stop5h 45mSouthwest
Tue 8/196:25 amRDU - JAN
2 stops7h 15mSouthwest
Deal found 7/24$265
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:00 pmGPT - RDU
1 stop5h 56mDelta
Mon 9/15:20 amRDU - GPT
1 stop5h 08mDelta
Deal found 7/22$274

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 8/22

10:23 am-1:28 pm

Nonstop2h 05m

Raleigh-Durham

Mon 8/25

8:33 am-9:43 am

Nonstop2h 10m

$98

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 9/25

8:35 pm-2:35 pm

2 stops17h 00m

Raleigh-Durham

Sun 9/28

10:40 am-3:26 pm

1 stop5h 46m

$220

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 9/11

7:30 am-12:47 pm

1 stop4h 17m

Raleigh-Durham

Tue 9/16

8:50 am-1:14 pm

1 stop5h 24m

$237

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Tue 8/19

8:30 am-5:20 pm

2 stops7h 50m

Raleigh-Durham

Sat 8/23

6:25 am-10:10 am

1 stop4h 45m

$242

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 9/25

6:56 pm-4:28 pm

1 stop20h 32m

Raleigh-Durham

Sun 9/28

6:52 pm-5:32 pm

1 stop23h 40m

$245

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 8/15

10:23 am-1:28 pm

Nonstop2h 05m

Raleigh-Durham

Sun 8/17

9:27 am-4:04 pm

1 stop7h 37m

$247

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Thu 8/14

6:15 am-2:02 pm

1 stop6h 47m

Raleigh-Durham

Thu 8/21

5:25 am-10:15 am

1 stop5h 50m

$249

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Sat 8/23

9:12 am-4:10 pm

1 stop5h 58m

Raleigh-Durham

Tue 8/26

10:45 am-3:56 pm

1 stop6h 11m

$249

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Tue 8/19

8:00 am-2:10 pm

1 stop5h 10m

Raleigh-Durham

Tue 8/26

11:23 am-7:31 pm

2 stops9h 08m

$254

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Thu 8/21

5:10 am-10:25 am

1 stop4h 15m

Raleigh-Durham

Sun 8/24

8:19 pm-11:56 pm

1 stop4h 37m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 45 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

How much does it cost to fly round-trip from Mississippi to Durham?

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated July 25, 2025.
See what other customers who have flown with Southwest, Delta, and Breeze Airways from Mississippi to Durham have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,967 reviews
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Breeze Airways
8.0
Very good
189 reviews
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,876 reviews
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,235 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $49. Spirit Airlines flights start at $114 while deals on American Airlines start at $119 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Jackson-Evers Intl - Raleigh-Durham. You may also consider Memphis - Raleigh-Durham or Gulfport Biloxi Regional - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$238Average$390FlexibilityNo cancel feeOn-timeN/A

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