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Durham

$49+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Aug 31 — Sep 71
Sun 8/31
Sun 9/7
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated August 26, 2025.

Round-trip from

$113
(Breeze Airways)

One-way from

$49
(Breeze Airways)

Popular in

October

Cheapest in

August

Average price

$286
From Mississippi to Durham
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One-way flight from Mississippi to Durham
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2025.

This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/511:30 amMEM - RDU
Nonstop1h 53mBreeze Airways
Mon 9/89:46 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 8/24$113
This Breeze Airways deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2211:30 amMEM - RDU
Nonstop1h 53mBreeze Airways
Mon 9/299:46 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 8/25$128
This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:30 amMEM - RDU
Nonstop1h 53mBreeze Airways
Mon 10/139:46 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 8/24$138
This Expedia deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:30 amMEM - RDU
Nonstop1h 53mBreeze Airways
Mon 11/1010:26 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 8/25$142
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:30 pmMEM - RDU
1 stop4h 55mSouthwest
Tue 9/306:00 pmRDU - MEM
1 stop5h 05mSouthwest
Deal found 8/24$177
This Priceline deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2211:30 amMEM - RDU
Nonstop1h 53mMultiple Airlines
Mon 9/299:23 amRDU - MEM
1 stop9h 20mMultiple Airlines
Deal found 8/25$183
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:45 amMEM - RDU
1 stop3h 34mAmerican Airlines
Sat 10/188:15 pmRDU - MEM
1 stop4h 44mAmerican Airlines
Deal found 8/25$199
This Priceline deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/511:30 amMEM - RDU
Nonstop1h 53mMultiple Airlines
Mon 9/89:23 amRDU - MEM
1 stop9h 20mMultiple Airlines
Deal found 8/24$206
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:00 amMEM - RDU
1 stop8h 21mMultiple Airlines
Sun 9/219:02 pmRDU - MEM
1 stop22h 58mMultiple Airlines
Deal found 8/24$218
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/148:35 pmMEM - RDU
1 stop12h 18mMultiple Airlines
Sat 9/277:03 pmRDU - MEM
1 stop5h 47mMultiple Airlines
Deal found 8/26$219
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:26 pmMEM - RDU
1 stop12h 09mMultiple Airlines
Sun 10/199:36 pmRDU - MEM
1 stop18h 13mMultiple Airlines
Deal found 8/24$225
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:57 pmMOB - RDU
1 stop4h 16mDelta
Sun 9/215:20 amRDU - MOB
1 stop4h 10mDelta
Deal found 8/26$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 26, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 9/5

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 9/8

9:46 am-10:50 am

Nonstop2h 04m

$113

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Mon 9/22

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 9/29

9:46 am-10:50 am

Nonstop2h 04m

$128

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 10/10

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 10/13

9:46 am-10:50 am

Nonstop2h 04m

$138

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Mon 11/3

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 11/10

10:26 am-11:30 am

Nonstop2h 04m

$138

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Tue 9/23

3:30 pm-9:25 pm

1 stop4h 55m

Raleigh-Durham

Tue 9/30

6:00 pm-10:05 pm

1 stop5h 05m

$177

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Mon 9/22

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 9/29

9:23 am-5:43 pm

1 stop9h 20m

$183

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Wed 10/15

6:45 am-11:19 am

1 stop3h 34m

Raleigh-Durham

Sat 10/18

8:15 pm-11:59 pm

1 stop4h 44m

$199

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 9/5

11:30 am-2:23 pm

Nonstop1h 53m

Raleigh-Durham

Mon 9/8

9:23 am-5:43 pm

1 stop9h 20m

$206

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 9/18

7:00 am-4:21 pm

1 stop8h 21m

Raleigh-Durham

Sun 9/21

9:02 pm-7:00 pm

1 stop22h 58m

$218

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Wed 2/18

7:15 pm-11:53 pm

1 stop3h 38m

Raleigh-Durham

Sat 2/21

6:30 pm-10:59 pm

1 stop5h 29m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/24

Showing 1-10 of 58 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 26, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

How much does it cost to fly round-trip from Mississippi to Durham?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Durham?

    There are many flights that can get you from Mississippi to Durham in 1h 53m. Fly via Breeze Airways, Delta, or American Airlines to get the fastest option. The distance from Mississippi to Durham is about 632 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $49. United Airlines flights start at $129 while deals on American Airlines start at $129 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Jackson-Evers Intl - Raleigh-Durham. You may also consider Memphis - Raleigh-Durham or Gulfport Biloxi Regional - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$239Average$400FlexibilityNo cancel feeOn-timeN/A

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