Durham

$94+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
May 6 — May 131
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Cheap flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$102
(Priceline)

One-way from

$94
(Mytrip)

Popular in

October

Cheapest in

September

Average price

$471
Provider with most accurate pricing for Jackson-Evers Intl-Raleigh-Durham flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Raleigh-Durham flights.
From Mississippi to Durham
One-way flight from Mississippi to Durham
High demand for flights, 5% potential price rise
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in May 2025

Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1610:38 amMEM - RDU
Nonstop2h 05mBreeze Airways
Mon 5/198:33 amRDU - MEM
Nonstop2h 10mBreeze Airways
Deal found 4/30$102
This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:14 pmMEM - RDU
1 stop4h 36mMultiple Airlines
Mon 5/198:33 amRDU - MEM
Nonstop2h 10mMultiple Airlines
Deal found 4/30$154
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:34 pmMEM - RDU
1 stop13h 38mSpirit Airlines
Sun 6/15:05 pmRDU - MEM
2 stops24h 14mSpirit Airlines
Deal found 4/30$220
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/66:31 pmMOB - RDU
1 stop4h 48mDelta
Sun 6/85:20 amRDU - MOB
1 stop4h 14mDelta
Deal found 4/30$244
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/176:32 pmBTR - RDU
1 stop4h 27mAmerican Airlines
Mon 7/215:16 amRDU - BTR
1 stop5h 57mAmerican Airlines
Deal found 4/30$249
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:05 pmGPT - RDU
1 stop3h 57mDelta
Sat 5/315:25 amRDU - GPT
1 stop4h 04mDelta
Deal found 4/29$249
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:10 amBTR - RDU
2 stops8h 03mUnited Airlines
Mon 7/215:00 pmRDU - BTR
1 stop7h 24mUnited Airlines
Deal found 4/30$254
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/109:55 amMEM - RDU
1 stop3h 28mDelta
Wed 6/118:51 amRDU - MEM
1 stop5h 26mDelta
Deal found 4/30$257
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/185:50 amJAN - RDU
1 stop6h 18mDelta
Sat 6/212:13 pmRDU - JAN
1 stop6h 25mDelta
Deal found 4/29$258
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:21 pmGPT - RDU
1 stop4h 37mAmerican Airlines
Mon 5/196:18 pmRDU - GPT
1 stop6h 40mAmerican Airlines
Deal found 4/30$259
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/276:25 pmJAN - RDU
1 stop4h 45mSouthwest
Mon 6/305:15 pmRDU - JAN
1 stop3h 40mSouthwest
Deal found 4/29$294
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:00 amMEM - RDU
2 stops6h 20mSouthwest
Fri 6/139:50 amRDU - MEM
1 stop5h 30mSouthwest
Deal found 4/30$299

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 5/16

10:38 am-1:43 pm

Nonstop2h 05m

Raleigh-Durham

Mon 5/19

8:33 am-9:43 am

Nonstop2h 10m

$102

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 5/15

1:14 pm-6:50 pm

1 stop4h 36m

Raleigh-Durham

Mon 5/19

8:33 am-9:43 am

Nonstop2h 10m

$154

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 5/29

6:34 pm-9:12 am

1 stop13h 38m

Raleigh-Durham

Sun 6/1

5:05 pm-4:19 pm

2 stops24h 14m

$220

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Fri 6/6

6:31 pm-12:19 am

1 stop4h 48m

Raleigh-Durham

Sun 6/8

5:20 am-8:34 am

1 stop4h 14m

$244

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Thu 7/17

6:32 pm-11:59 pm

1 stop4h 27m

Raleigh-Durham

Mon 7/21

5:16 am-10:13 am

1 stop5h 57m

$249

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Fri 5/30

6:05 pm-11:02 pm

1 stop3h 57m

Raleigh-Durham

Sat 5/31

5:25 am-8:29 am

1 stop4h 04m

$249

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Thu 7/17

5:10 am-2:13 pm

2 stops8h 03m

Raleigh-Durham

Mon 7/21

5:00 pm-11:24 pm

1 stop7h 24m

$254

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Tue 6/10

9:55 am-2:23 pm

1 stop3h 28m

Raleigh-Durham

Wed 6/11

8:51 am-1:17 pm

1 stop5h 26m

$257

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Wed 6/18

5:50 am-1:08 pm

1 stop6h 18m

Raleigh-Durham

Sat 6/21

2:13 pm-7:38 pm

1 stop6h 25m

$258

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Thu 5/15

6:21 pm-11:58 pm

1 stop4h 37m

Raleigh-Durham

Mon 5/19

6:18 pm-11:58 pm

1 stop6h 40m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 38 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated May 1, 2025.
See what other customers who have flown with Breeze Airways, Southwest and Delta from Mississippi to Durham have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Comfort

8.2

Food

6.7

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $95. Breeze Airways flights start at $99 while deals on Delta start at $104 one-way.

  • What are the most popular routes from Mississippi to Durham?

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$427FlexibilityNo cancel feeOn-time71%

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