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Durham

$58+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amGPT - RDU
1 stop6h 00mDelta
Sat 1/1010:01 amRDU - GPT
1 stop6h 08mDelta
Deal found 12/26$324
This Expedia deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:18 pmMEM - RDU
1 stop6h 55mMultiple Airlines
Fri 1/210:26 amRDU - MEM
Nonstop2h 04mMultiple Airlines
Deal found 12/26$351
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:34 pmBTR - RDU
1 stop4h 14mAmerican Airlines
Fri 1/25:01 amRDU - BTR
1 stop5h 38mAmerican Airlines
Deal found 12/26$354
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:00 amGPT - RDU
1 stop7h 46mUnited Airlines
Fri 1/26:10 amRDU - GPT
1 stop8h 12mUnited Airlines
Deal found 12/26$354
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:57 pmGPT - RDU
1 stop7h 02mUnited Airlines
Wed 1/76:15 amRDU - GPT
1 stop8h 07mUnited Airlines
Deal found 12/24$378
This Breeze Airways deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:10 pmMEM - RDU
Nonstop1h 53mBreeze Airways
Mon 12/2910:26 amRDU - MEM
Nonstop2h 04mBreeze Airways
Deal found 12/26$398
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:10 pmMEM - RDU
Nonstop1h 53mMultiple Airlines
Mon 12/299:37 pmRDU - MEM
1 stop22h 45mMultiple Airlines
Deal found 12/26$421
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:50 pmGPT - RDU
1 stop12h 17mMultiple Airlines
Sat 1/108:06 pmRDU - GPT
2 stops37h 54mMultiple Airlines
Deal found 12/26$433
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:35 amMEM - RDU
2 stops12h 09mUnited Airlines
Sat 1/38:29 amRDU - MEM
1 stop7h 19mUnited Airlines
Deal found 12/26$648
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amMEM - RDU
1 stop6h 00mDelta
Fri 1/25:30 amRDU - MEM
1 stop4h 15mDelta
Deal found 12/26$667
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:10 amMEM - RDU
2 stops8h 45mSouthwest
Fri 1/28:35 pmRDU - MEM
1 stop4h 30mSouthwest
Deal found 12/26$672
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:00 amGPT - RDU
1 stop7h 46mUnited Airlines
Sat 1/1010:10 amRDU - GPT
3 stops34h 38mUnited Airlines
Deal found 12/26$677

Find flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$158
(Breeze Airways)

One-way from

$58
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$388
Provider with most accurate pricing for Jackson-Evers Intl-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Raleigh-Durham flights.
Search Deals
From Mississippi to Durham
Search Deals
One-way flight from Mississippi to Durham
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 6/5

2:05 pm-5:07 pm

Nonstop2h 02m

Raleigh-Durham

Mon 6/8

7:05 am-8:05 am

Nonstop2h 00m

$168

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Tue 1/27

11:44 am-4:30 pm

1 stop27h 46m

Raleigh-Durham

Tue 2/3

2:54 pm-10:49 am

1 stop20h 55m

$170

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Tue 2/3

11:44 am-4:30 pm

1 stop27h 46m

Raleigh-Durham

Tue 2/10

5:54 pm-10:49 am

1 stop17h 55m

$170

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 1/30

5:25 pm-2:11 pm

1 stop19h 46m

Raleigh-Durham

Tue 2/3

2:54 pm-10:49 am

1 stop20h 55m

$172

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 1/16

5:25 pm-2:11 pm

1 stop19h 46m

Raleigh-Durham

Mon 1/19

8:16 pm-10:49 am

1 stop15h 33m

$172

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 1/30

5:25 pm-2:11 pm

1 stop19h 46m

Raleigh-Durham

Thu 2/5

6:10 am-5:40 pm

1 stop12h 30m

$180

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 1/23

5:25 pm-8:58 am

2 stops14h 33m

Raleigh-Durham

Sun 1/25

9:56 pm-10:49 am

1 stop13h 53m

$188

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 1/16

5:25 pm-2:11 pm

1 stop19h 46m

Raleigh-Durham

Sun 1/18

9:22 am-4:52 pm

1 stop8h 30m

$189

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Fri 2/6

6:54 pm-8:58 am

1 stop13h 04m

Raleigh-Durham

Sun 2/8

3:22 pm-9:00 am

1 stop18h 38m

$193

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Sat 1/31

11:44 am-7:20 pm

1 stop6h 36m

Raleigh-Durham

Tue 2/3

2:54 pm-10:49 am

1 stop20h 55m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $185). Flying from Mississippi to Durham in October is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Durham?

    There are many flights that can get you from Mississippi to Durham in 2h 02m. Fly via Breeze Airways, American Airlines, or Delta to get the fastest option. The distance from Mississippi to Durham is about 632 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Memphis - Raleigh-Durham. You may also consider Gulfport Biloxi Regional - Raleigh-Durham or Alexandria - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $185). Flying from Mississippi to Durham in October is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$226Average$349FlexibilityNo cancel feeOn-timeN/A

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