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Des Moines

$118+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Milwaukee to Des Moines

Cheapest flights from Milwaukee to Des Moines
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:08 pmMKE - DSM
1 stop36h 07mAmerican Airlines
Fri 1/26:57 pmDSM - MKE
1 stop4h 03mAmerican Airlines
Deal found 12/2$332
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:08 pmMKE - DSM
1 stop16h 46mAmerican Airlines
Fri 1/23:27 pmDSM - MKE
1 stop4h 11mAmerican Airlines
Deal found 12/4$352
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:45 amMKE - DSM
1 stop24h 30mAmerican Airlines
Mon 12/221:18 pmDSM - MKE
1 stop30h 10mAmerican Airlines
Deal found 12/2$402
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:36 amMKE - DSM
1 stop15h 04mUnited Airlines
Sat 1/36:46 pmDSM - MKE
1 stop3h 27mUnited Airlines
Deal found 12/2$412
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:00 amMKE - DSM
1 stop5h 50mUnited Airlines
Sat 1/36:46 pmDSM - MKE
1 stop3h 27mUnited Airlines
Deal found 12/2$413
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:51 pmMKE - DSM
1 stop3h 53mAmerican Airlines
Sat 12/135:30 amDSM - MKE
1 stop5h 13mAmerican Airlines
Deal found 12/2$528
This Southwest deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:25 amMKE - DSM
1 stop5h 30mSouthwest
Fri 1/25:30 amDSM - MKE
2 stops12h 55mSouthwest
Deal found 12/2$532
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:29 amMKE - DSM
1 stop5h 34mDelta
Sun 12/72:59 pmDSM - MKE
1 stop3h 52mDelta
Deal found 12/1$549
This Southwest deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:05 pmMKE - DSM
1 stop5h 30mSouthwest
Sun 12/75:45 amDSM - MKE
2 stops11h 40mSouthwest
Deal found 12/1$554
This Southwest deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:45 amMKE - DSM
2 stops9h 10mSouthwest
Mon 12/86:15 amDSM - MKE
2 stops5h 45mSouthwest
Deal found 12/2$565
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:27 pmMKE - DSM
2 stops20h 36mMultiple Airlines
Mon 12/221:56 pmDSM - MKE
1 stop8h 41mMultiple Airlines
Deal found 12/2$575
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:15 pmMKE - DSM
2 stops18h 42mMultiple Airlines
Tue 12/233:45 pmDSM - MKE
2 stops27h 35mMultiple Airlines
Deal found 12/3$652

Find flight deals from Milwaukee to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$177
(Delta)

One-way from

$118
(Delta)
Provider with most accurate pricing for Milwaukee-Mitchell-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Des Moines flights.
Search Deals
From Milwaukee-Mitchell to Des Moines
Search Deals
One-way flight from Milwaukee-Mitchell to Des Moines
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Milwaukee

Fly to

Des Moines

Route

Depart

Return

Price

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 1/6

3:59 pm-9:24 pm

1 stop5h 25m

Des Moines

Wed 1/7

10:59 am-3:19 pm

1 stop4h 20m

$177

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 1/6

6:00 am-10:55 am

1 stop4h 55m

Des Moines

Wed 1/7

8:00 am-12:09 pm

1 stop4h 09m

$219

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 2/14

3:30 pm-9:51 pm

1 stop6h 21m

Des Moines

Wed 2/18

3:24 pm-8:55 pm

1 stop5h 31m

$229

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 1/11

11:03 am-3:41 pm

1 stop4h 38m

Des Moines

Sat 1/31

6:54 am-10:23 am

1 stop3h 29m

$233

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 1/11

7:00 am-10:55 am

1 stop3h 55m

Des Moines

Sat 1/31

7:50 am-12:09 pm

1 stop4h 19m

$233

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 1/24

3:20 pm-9:50 pm

1 stop6h 30m

Des Moines

Sun 1/25

6:48 pm-10:56 pm

1 stop4h 08m

$233

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 1/11

4:30 pm-10:15 pm

2 stops5h 45m

Des Moines

Sat 1/31

5:45 am-1:30 pm

1 stop7h 45m

$292

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 12/27

8:08 pm-8:15 am

1 stop36h 07m

Des Moines

Fri 1/2

6:57 pm-11:00 pm

1 stop4h 03m

$332

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 12/25

6:25 am-11:28 am

1 stop5h 03m

$118

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 12/27

7:48 pm-9:22 am

1 stop13h 34m

$182

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 16 results
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Compare providers for flights from Milwaukee to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Des Moines

What is the cheapest month to book a flight from Milwaukee to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $181). Flying from Milwaukee to Des Moines in April is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Des Moines?

    Airlines like Delta and United Airlines fly from Milwaukee to Des Moines in about 4h 55m. The time it takes to get you to your destination can typically vary by up to 30m. There are 310 mi between Milwaukee and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Milwaukee to Des Moines that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Des Moines.

  • Can I find deals for business class flights from Milwaukee to Des Moines?

    Yes. Cheapflights offers flight deals from Milwaukee to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $181). Flying from Milwaukee to Des Moines in April is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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