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Des Moines

$235+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Milwaukee to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$228
(United Airlines)
Provider with most accurate pricing for Milwaukee-Mitchell-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Des Moines flights.
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From Milwaukee-Mitchell to Des Moines
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Find flight deals from Milwaukee to Des Moines

Cheapest flights from Milwaukee to Des Moines
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:00 amMKE - DSM
1 stop4h 21mDelta
Thu 12/46:50 amDSM - MKE
1 stop3h 44mDelta
Deal found 10/13$235
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:10 amMKE - DSM
1 stop4h 10mDelta
Mon 11/243:30 pmDSM - MKE
1 stop5h 38mDelta
Deal found 10/15$238
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:10 amMKE - DSM
1 stop4h 10mDelta
Sat 11/1512:30 pmDSM - MKE
1 stop3h 42mDelta
Deal found 10/14$257
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:50 amMKE - DSM
1 stop5h 10mSouthwest
Sat 11/156:25 amDSM - MKE
2 stops9h 25mSouthwest
Deal found 10/14$268
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:00 amMKE - DSM
1 stop5h 30mUnited Airlines
Fri 10/311:05 pmDSM - MKE
1 stop4h 12mUnited Airlines
Deal found 10/14$298
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:09 pmMKE - DSM
1 stop3h 23mAmerican Airlines
Sun 11/96:40 pmDSM - MKE
1 stop4h 25mAmerican Airlines
Deal found 10/15$327
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:25 pmMKE - DSM
1 stop4h 55mSouthwest
Mon 11/245:45 amDSM - MKE
2 stops11h 40mSouthwest
Deal found 10/15$354
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amMKE - DSM
1 stop26h 22mAmerican Airlines
Sat 11/111:58 amDSM - MKE
1 stop9h 26mAmerican Airlines
Deal found 10/15$377
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:10 pmMKE - DSM
1 stop5h 20mSouthwest
Fri 10/318:25 amDSM - MKE
2 stops12h 20mSouthwest
Deal found 10/14$418
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:53 amMKE - DSM
1 stop3h 26mUnited Airlines
Mon 11/38:02 amDSM - MKE
1 stop3h 22mUnited Airlines
Deal found 10/15$459

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Milwaukee

Fly to

Des Moines

Route

Depart

Return

Price

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 12/2

6:00 am-10:21 am

1 stop4h 21m

Des Moines

Thu 12/4

6:50 am-10:34 am

1 stop3h 44m

$235

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 11/22

6:10 am-10:20 am

1 stop4h 10m

Des Moines

Mon 11/24

3:30 pm-9:08 pm

1 stop5h 38m

$238

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 11/14

6:10 am-10:20 am

1 stop4h 10m

Des Moines

Sat 11/15

12:30 pm-4:12 pm

1 stop3h 42m

$257

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 11/14

5:50 am-11:00 am

1 stop5h 10m

Des Moines

Sat 11/15

6:25 am-3:50 pm

2 stops9h 25m

$268

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 10/30

5:00 am-10:30 am

1 stop5h 30m

Des Moines

Fri 10/31

1:05 pm-5:17 pm

1 stop4h 12m

$298

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 10/31

10:53 am-2:19 pm

1 stop3h 26m

Des Moines

Tue 11/4

11:26 am-4:32 pm

1 stop5h 06m

$298

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 11/7

12:09 pm-3:32 pm

1 stop3h 23m

Des Moines

Sun 11/9

6:40 pm-11:05 pm

1 stop4h 25m

$327

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 11/22

8:25 pm-1:20 am

1 stop4h 55m

Des Moines

Mon 11/24

5:45 am-5:25 pm

2 stops11h 40m

$354

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 10/29

6:00 am-8:22 am

1 stop26h 22m

Des Moines

Sat 11/1

11:58 am-9:24 pm

1 stop9h 26m

$377

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 10/30

6:10 pm-11:30 pm

1 stop5h 20m

Des Moines

Fri 10/31

8:25 am-8:45 pm

2 stops12h 20m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Showing 1-10 of 12 results
1
2

Compare providers for flights from Milwaukee to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Des Moines

What is the cheapest month to book a flight from Milwaukee to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $182). Flying from Milwaukee to Des Moines in April is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 16, 2025.
See what other customers who have flown with American Airlines from Milwaukee to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,043 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,043 reviews
American Airlines
7.2
Good
11,043 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Des Moines?

    Airlines like Delta and Southwest fly from Milwaukee to Des Moines in about 4h 21m. The time it takes to get you to your destination can typically vary by up to 49m. There are 310 mi between Milwaukee and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Milwaukee to Des Moines round-trip?

    American Airlines, at $174, was found to be the cheapest airline from Milwaukee to Des Moines..

  • Can I find deals for flights from Milwaukee to Des Moines that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Des Moines.

  • Can I find deals for business class flights from Milwaukee to Des Moines?

    Yes. Cheapflights offers flight deals from Milwaukee to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $182). Flying from Milwaukee to Des Moines in April is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from Milwaukee to Des Moines

Discover the top airline that operate flights from Milwaukee to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$174Average$382FlexibilityNo cancel feeOn-time71%

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