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Des Moines

$128+ Cheap flights from Milwaukee to Des Moines (MKE - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — DSM
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Milwaukee to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$239
(United Airlines)

One-way from

$128
(Delta)
Provider with most accurate pricing for Milwaukee-Mitchell-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Des Moines flights.
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From Milwaukee-Mitchell to Des Moines
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One-way flight from Milwaukee-Mitchell to Des Moines
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Find flight deals from Milwaukee to Des Moines

Cheapest flights from Milwaukee to Des Moines
Explore the most affordable flight options available from Milwaukee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:00 am
MKE
-
DSM
1 stop4h 55m
United Airlines
Wed 2/188:00 am
DSM
-
MKE
1 stop4h 35m
United Airlines
Deal found 1/14$239
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:30 am
MKE
-
DSM
1 stop5h 55m
Southwest
Wed 2/256:10 am
DSM
-
MKE
2 stops5h 45m
Southwest
Deal found 1/14$244
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:45 am
MKE
-
DSM
1 stop3h 33m
Delta
Sat 4/254:24 pm
DSM
-
MKE
1 stop6h 22m
Delta
Deal found 1/13$255
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:15 am
MKE
-
DSM
1 stop4h 02m
Delta
Sun 3/16:50 am
DSM
-
MKE
1 stop3h 31m
Delta
Deal found 1/14$287
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:00 am
MKE
-
DSM
1 stop5h 53m
United Airlines
Wed 2/188:00 am
DSM
-
MKE
1 stop4h 35m
United Airlines
Deal found 1/13$305
This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:00 am
MKE
-
DSM
2 stops15h 05m
Southwest
Sat 4/252:10 pm
DSM
-
MKE
1 stop7h 40m
Southwest
Deal found 1/13$323
This Southwest deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:50 am
MKE
-
DSM
1 stop5h 40m
Southwest
Sun 4/264:20 pm
DSM
-
MKE
2 stops7h 35m
Southwest
Deal found 1/15$362
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:45 am
MKE
-
DSM
1 stop3h 33m
Delta
Sun 4/264:24 pm
DSM
-
MKE
1 stop3h 26m
Delta
Deal found 1/15$376

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Milwaukee

Fly to

Des Moines

Route

Depart

Return

Price

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 2/18

9:44 am-2:27 pm

1 stop4h 43m

Des Moines

Wed 2/25

8:00 am-12:35 pm

1 stop4h 35m

$239

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 5/5

5:00 am-11:28 am

1 stop6h 28m

Des Moines

Wed 5/6

6:00 am-10:51 am

1 stop4h 51m

$239

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 2/11

1:04 pm-4:24 pm

1 stop3h 20m

Des Moines

Wed 2/18

7:44 pm-10:57 pm

1 stop3h 13m

$239

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 5/12

6:45 am-10:37 am

1 stop3h 52m

Des Moines

Sat 5/16

3:20 pm-9:48 pm

1 stop6h 28m

$247

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/23

6:45 am-10:18 am

1 stop3h 33m

Des Moines

Sat 4/25

4:24 pm-10:46 pm

1 stop6h 22m

$255

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 2/18

12:10 pm-9:10 pm

2 stops9h 00m

Des Moines

Wed 2/25

6:10 am-11:55 am

2 stops5h 45m

$272

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 5/12

5:50 am-11:25 am

1 stop5h 35m

Des Moines

Sat 5/16

5:35 am-8:40 pm

2 stops15h 05m

$284

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 2/27

6:15 am-10:17 am

1 stop4h 02m

Des Moines

Sun 3/1

6:50 am-10:21 am

1 stop3h 31m

$287

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 2/14

5:00 am-10:53 am

1 stop5h 53m

Des Moines

Wed 2/18

8:00 am-12:35 pm

1 stop4h 35m

$305

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/23

8:00 am-11:05 pm

2 stops15h 05m

Des Moines

Sat 4/25

2:10 pm-9:50 pm

1 stop7h 40m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 18 results
1
2

Compare providers for flights from Milwaukee to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Milwaukee-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Milwaukee-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Milwaukee-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Milwaukee-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Des Moines

What is the cheapest month to book a flight from Milwaukee to Des Moines?

Currently, February is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $179). Flying from Milwaukee to Des Moines in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 15, 2026.
See what other customers who have flown with American Airlines from Milwaukee to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,136 reviews

Boarding

7.5

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,136 reviews
American Airlines
7.2
Good
11,136 reviews

Boarding

7.5

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Des Moines?

    Airlines like United Airlines, American Airlines, and Delta fly from Milwaukee to Des Moines in about 3h 33m. The time it takes to get you to your destination can typically vary by up to 2h 55m. There are 310 mi between Milwaukee and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Milwaukee to Des Moines round-trip?

    American Airlines, at $174, was found to be the cheapest airline from Milwaukee to Des Moines..

  • Can I find deals for flights from Milwaukee to Des Moines that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Des Moines.

  • Can I find deals for business class flights from Milwaukee to Des Moines?

    Yes. Cheapflights offers flight deals from Milwaukee to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Des Moines?

    Currently, February is the cheapest month in which you can book a flight from Milwaukee to Des Moines (average of $179). Flying from Milwaukee to Des Moines in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Top airline flying from Milwaukee to Des Moines

Discover the top airline that operate flights from Milwaukee to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$174Average$288FlexibilityNo cancel feeOn-time71%

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