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Des Moines

$274+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 16, 2025.

Round-trip from

$437
(Kiwi.com)

One-way from

$274
(SmartFares)

Popular in

December

Cheapest in

June

Average price

$582
From Mexico City Benito Juarez to Des Moines
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One-way flight from Mexico City Benito Juarez to Des Moines
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Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2910:30 pmMEX - DSM
2 stops38h 57mMultiple Airlines
Mon 10/63:40 pmDSM - MEX
1 stop29h 10mMultiple Airlines
Deal found 8/15$437
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:45 pmMEX - DSM
2 stops24h 31mMultiple Airlines
Fri 9/268:25 amDSM - MEX
2 stops15h 30mMultiple Airlines
Deal found 8/14$484
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/294:40 pmMEX - DSM
2 stops16h 52mUnited Airlines
Mon 10/63:25 pmDSM - MEX
2 stops8h 45mUnited Airlines
Deal found 8/15$499
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:01 amMEX - DSM
2 stops15h 42mDelta
Wed 9/175:44 amDSM - MEX
2 stops12h 26mDelta
Deal found 8/14$500
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/810:00 amMEX - DSM
2 stops11h 43mDelta
Tue 9/235:44 amDSM - MEX
2 stops13h 26mDelta
Deal found 8/15$552
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:40 amMEX - DSM
3 stops16h 05mUnited Airlines
Wed 9/178:00 amDSM - MEX
2 stops8h 40mUnited Airlines
Deal found 8/14$566
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/271:10 pmMEX - DSM
1 stop9h 07mAmerican Airlines
Fri 9/265:10 amDSM - MEX
1 stop12h 05mAmerican Airlines
Deal found 8/14$630
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:35 amMEX - DSM
1 stop11h 53mUnited Airlines
Fri 9/261:33 pmDSM - MEX
2 stops10h 37mUnited Airlines
Deal found 8/14$642

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Mexico City

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 9/29

10:30 pm-2:27 pm

2 stops38h 57m

Des Moines

Mon 10/6

3:40 pm-7:50 pm

1 stop29h 10m

$437

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 8/27

7:45 pm-9:16 pm

2 stops24h 31m

Des Moines

Fri 9/26

8:25 am-10:55 pm

2 stops15h 30m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 9/29

4:40 pm-10:32 am

2 stops16h 52m

Des Moines

Mon 10/6

3:25 pm-11:10 pm

2 stops8h 45m

$499

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 9/10

1:15 pm-10:43 pm

1 stop8h 28m

Des Moines

Wed 9/17

7:00 am-12:40 pm

1 stop6h 40m

$500

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 9/8

1:15 pm-10:43 pm

1 stop8h 28m

Des Moines

Tue 9/23

2:05 pm-7:40 pm

1 stop6h 35m

$552

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 9/13

8:10 am-1:40 pm

1 stop28h 30m

$274

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 9/8

11:00 am-10:29 pm

1 stop10h 29m

$297

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 9/13

8:10 am-4:59 pm

2 stops31h 49m

$332

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 9/8

2:15 pm-12:36 pm

2 stops21h 21m

$360

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 9/13

4:40 am-9:45 pm

3 stops16h 05m

$524

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 12 results
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Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest time of day to fly from MEX to DSM?

Find hourly flight availability from Mexico City to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mexico City to Des Moines as you normally would.

How much does it cost to fly round-trip from Mexico City to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $336). Flying from Mexico City to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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