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Des Moines

$217+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Find cheap flights from Mexico City to Des Moines with Cheapflights

1. Tell us where you want to go

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Cheap flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:15 am
MEX
-
DSM
2 stops33h 59m
Multiple Airlines
Fri 4/1010:11 pm
DSM
-
MEX
1 stop24h 34m
Multiple Airlines
Deal found 3/20$547
This PocketFare deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure PocketFare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:40 am
MEX
-
DSM
1 stop27h 51m
Frontier
Fri 8/142:16 pm
DSM
-
MEX
1 stop28h 14m
Frontier
Deal found 3/20$548
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:05 am
MEX
-
DSM
1 stop21h 28m
Multiple Airlines
Sat 5/911:00 am
DSM
-
MEX
2 stops34h 05m
Multiple Airlines
Deal found 3/19$562
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:00 am
MEX
-
DSM
1 stop15h 16m
American Airlines
Tue 5/125:19 am
DSM
-
MEX
1 stop10h 00m
American Airlines
Deal found 3/21$569
This Aeromexico deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:00 pm
MEX
-
DSM
2 stops19h 45m
Aeromexico
Tue 5/1211:57 am
DSM
-
MEX
1 stop8h 03m
Aeromexico
Deal found 3/21$573
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:30 am
MEX
-
DSM
1 stop15h 05m
United Airlines
Wed 9/305:00 am
DSM
-
MEX
2 stops11h 40m
United Airlines
Deal found 3/22$575
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:40 am
MEX
-
DSM
2 stops11h 37m
Delta
Sun 8/3010:55 am
DSM
-
MEX
2 stops9h 05m
Delta
Deal found 3/21$577
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:55 am
MEX
-
DSM
2 stops34h 19m
Frontier
Fri 4/108:14 pm
DSM
-
MEX
2 stops51h 01m
Frontier
Deal found 3/20$596
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:55 am
MEX
-
DSM
1 stop11h 13m
American Airlines
Fri 8/146:30 am
DSM
-
MEX
1 stop10h 41m
American Airlines
Deal found 3/22$604

Find flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$547
(Kiwi.com)

One-way from

$246
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$688
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico City Benito Juarez to Des Moines
Search Deals
One-way flight from Mexico City Benito Juarez to Des Moines
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 7/25

6:30 am-10:35 pm

1 stop15h 05m

Des Moines

Wed 9/30

5:00 am-3:40 pm

2 stops11h 40m

$575

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 8/27

8:40 am-9:17 pm

2 stops11h 37m

Des Moines

Sun 8/30

10:55 am-7:00 pm

2 stops9h 05m

$577

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

10:55 am-11:08 pm

1 stop11h 13m

Des Moines

Fri 8/14

6:30 am-4:11 pm

1 stop10h 41m

$604

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 8/28

8:40 am-10:26 pm

1 stop12h 46m

Des Moines

Sun 8/30

2:15 pm-9:15 pm

1 stop8h 00m

$606
Quickest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

2:15 pm-10:35 pm

1 stop7h 20m

Des Moines

Fri 8/14

5:00 am-1:15 pm

2 stops9h 15m

$606

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/9

11:35 am-10:43 pm

1 stop10h 08m

Des Moines

Sat 5/9

2:58 pm-11:10 pm

1 stop9h 12m

$613
Cheapest one-way

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 5/12

8:40 am-1:31 pm

1 stop27h 51m

$233

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 7/7

8:40 am-1:31 pm

1 stop27h 51m

$270

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 6/11

11:00 am-10:53 pm

2 stops34h 53m

$300

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/3

11:00 am-7:25 pm

1 stop31h 25m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Mexico City to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Des Moines in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest month to book a flight from Mexico City to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $478). Flying from Mexico City to Des Moines in March is currently the most expensive (average of $688). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 11h 37m. Fly via United Airlines or Delta to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $478). Flying from Mexico City to Des Moines in March is currently the most expensive (average of $688). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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