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Des Moines

$384+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$400
(Kiwi.com)

One-way from

$384
(United Airlines)

Popular in

October

Cheapest in

June

Average price

$677
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
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From Mexico City Benito Juarez to Des Moines
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One-way flight from Mexico City Benito Juarez to Des Moines
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Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:30 amMEX - DSM
2 stops14h 33mMultiple Airlines
Mon 12/87:58 pmDSM - MEX
2 stops26h 02mMultiple Airlines
Deal found 10/16$471
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:05 amMEX - DSM
2 stops28h 15mUnited Airlines
Mon 12/82:53 pmDSM - MEX
1 stop19h 12mUnited Airlines
Deal found 10/16$521
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/159:35 amMEX - DSM
2 stops11h 55mDelta
Wed 10/227:03 amDSM - MEX
2 stops9h 42mDelta
Deal found 10/14$562
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:13 pmMEX - DSM
1 stop18h 27mAmerican Airlines
Mon 12/83:38 pmDSM - MEX
1 stop6h 17mAmerican Airlines
Deal found 10/16$597
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2910:05 amMEX - DSM
1 stop12h 15mUnited Airlines
Sat 12/65:45 amDSM - MEX
1 stop16h 45mUnited Airlines
Deal found 10/14$600
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:35 amMEX - DSM
2 stops11h 28mDelta
Sat 11/87:03 amDSM - MEX
2 stops14h 37mDelta
Deal found 10/14$604
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amMEX - DSM
1 stop11h 09mAmerican Airlines
Sun 12/285:39 pmDSM - MEX
1 stop16h 16mAmerican Airlines
Deal found 10/14$614
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/309:10 amMEX - DSM
1 stop10h 14mMultiple Airlines
Sun 12/78:30 amDSM - MEX
1 stop11h 35mMultiple Airlines
Deal found 10/15$618
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:00 amMEX - DSM
2 stops14h 15mDelta
Sat 12/66:50 amDSM - MEX
2 stops14h 50mDelta
Deal found 10/14$668
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:45 pmMEX - DSM
2 stops20h 34mUnited Airlines
Sun 12/75:45 amDSM - MEX
2 stops18h 25mUnited Airlines
Deal found 10/15$724

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Mexico City

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/1

8:30 am-11:03 pm

2 stops14h 33m

Des Moines

Mon 12/8

7:58 pm-10:00 pm

2 stops26h 02m

$471

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

8:40 am-4:30 pm

1 stop7h 50m

Des Moines

Mon 3/9

5:15 pm-10:20 am

1 stop18h 05m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

12:25 pm-10:36 pm

1 stop10h 11m

Des Moines

Mon 3/9

8:00 am-5:55 pm

2 stops10h 55m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/1

10:05 am-2:20 pm

2 stops28h 15m

Des Moines

Mon 12/8

2:53 pm-10:05 am

1 stop19h 12m

$521

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/1

4:13 pm-10:40 am

1 stop18h 27m

Des Moines

Mon 12/8

3:38 pm-9:55 pm

1 stop6h 17m

$597

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 11/29

10:05 am-10:20 pm

1 stop12h 15m

$384

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 11/30

7:50 am-12:14 pm

2 stops28h 24m

$385

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 11/30

9:10 am-7:24 pm

1 stop10h 14m

$431

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 11/28

1:05 am-1:42 am

2 stops24h 37m

$730

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 11/30

1:30 pm-11:44 pm

3 stops34h 14m

$1,573

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Compare providers for flights from Mexico City to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Des Moines in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest time of day to fly from MEX to DSM?

Find hourly flight availability from Mexico City to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 41% on flights from Mexico City to Des Moines by exploring options for tickets at noon.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 7h 50m. Fly via Delta or United Airlines to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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