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Des Moines

$265+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
May 21 — May 281
Thu 5/21
Thu 5/28
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:20 am
MEX
-
DSM
2 stops30h 11m
Multiple Airlines
Sun 6/78:36 pm
DSM
-
MEX
1 stop24h 29m
Multiple Airlines
Deal found 4/21$457
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
MEX
-
DSM
1 stop9h 06m
Multiple Airlines
Mon 6/82:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Deal found 4/17$477
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:00 am
MEX
-
DSM
1 stop9h 11m
Multiple Airlines
Sun 5/1011:00 am
DSM
-
MEX
1 stop10h 05m
Multiple Airlines
Deal found 4/17$508
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:00 am
MEX
-
DSM
2 stops15h 24m
Multiple Airlines
Mon 8/1710:06 pm
DSM
-
MEX
1 stop24h 39m
Multiple Airlines
Deal found 4/19$517
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
MEX
-
DSM
1 stop9h 06m
Multiple Airlines
Sun 6/78:36 pm
DSM
-
MEX
1 stop24h 29m
Multiple Airlines
Deal found 4/17$545

Find flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$457
(Kiwi.com)

One-way from

$265
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$680
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico City Benito Juarez to Des Moines
Search Deals
One-way flight from Mexico City Benito Juarez to Des Moines
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 6/2

9:35 am-11:16 pm

2 stops12h 41m

Des Moines

Sun 6/7

8:15 pm-12:45 pm

1 stop17h 30m

$557

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 6/5

4:40 pm-10:27 am

2 stops16h 47m

Des Moines

Mon 6/8

1:35 pm-11:10 pm

2 stops10h 35m

$577

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 6/1

7:05 pm-10:16 am

2 stops14h 11m

Des Moines

Mon 8/17

7:00 am-4:05 pm

2 stops10h 05m

$579

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 8/28

8:40 am-10:26 pm

1 stop12h 46m

Des Moines

Sun 8/30

5:45 am-7:00 pm

1 stop14h 15m

$593
Quickest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 6/2

7:05 am-5:53 pm

1 stop9h 48m

Des Moines

Sun 6/7

6:43 am-3:30 pm

2 stops9h 47m

$598

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 5/15

4:40 pm-10:37 am

2 stops16h 57m

Des Moines

Mon 5/18

3:20 pm-10:45 am

2 stops20h 25m

$601

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

6:30 am-7:25 pm

2 stops11h 55m

Des Moines

Fri 8/14

6:00 am-3:40 pm

2 stops10h 40m

$605
Cheapest one-way

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/10

8:40 am-1:31 pm

1 stop27h 51m

$265

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 6/1

10:05 am-1:31 pm

3 stops50h 26m

$266

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 5/26

11:00 am-12:59 pm

1 stop24h 59m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Mexico City to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Des Moines in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest month to book a flight from Mexico City to Des Moines?

Currently, February is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $484). Flying from Mexico City to Des Moines in March is currently the most expensive (average of $688). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mexico City to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 11h 25m. Fly via United Airlines to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Des Moines?

    Currently, February is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $484). Flying from Mexico City to Des Moines in March is currently the most expensive (average of $688). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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