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Des Moines

$504+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$504
(Delta)

Popular in

December

Cheapest in

June

Average price

$521
From Mexico City Benito Juarez to Des Moines
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:25 pmMEX - DSM
1 stop7h 53mAmerican Airlines
Fri 10/105:04 amDSM - MEX
1 stop12h 11mAmerican Airlines
Deal found 9/13$702
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:40 amMEX - DSM
2 stops11h 50mDelta
Fri 10/106:39 pmDSM - MEX
2 stops14h 21mDelta
Deal found 9/13$728
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:15 pmMEX - DSM
2 stops21h 30mDelta
Sat 9/2011:25 amDSM - MEX
1 stop9h 15mDelta
Deal found 9/13$947
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:15 amMEX - DSM
2 stops20h 35mAir Canada
Fri 10/101:00 pmDSM - MEX
2 stops11h 15mAir Canada
Deal found 9/13$1,871

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Mexico City

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

8:40 am-4:30 pm

1 stop7h 50m

Des Moines

Mon 3/9

5:15 pm-10:20 am

1 stop18h 05m

$504

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

9:05 am-4:14 pm

1 stop7h 09m

Des Moines

Mon 3/9

1:45 pm-11:10 pm

2 stops10h 25m

$504

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 9/26

3:25 pm-12:18 am

1 stop7h 53m

Des Moines

Fri 10/10

5:04 am-4:15 pm

1 stop12h 11m

$702

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 9/26

7:40 am-8:30 pm

2 stops11h 50m

Des Moines

Fri 10/10

6:39 pm-8:00 am

2 stops14h 21m

$728

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 3/4

1:05 am-2:11 pm

2 stops13h 06m

Des Moines

Mon 3/9

6:45 pm-11:30 am

2 stops17h 45m

$1,819

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest time of day to fly from MEX to DSM?

Find hourly flight availability from Mexico City to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mexico City to Des Moines as you normally would.

How much does it cost to fly round-trip from Mexico City to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 7h 09m. Fly via Delta or United Airlines to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $336). Flying from Mexico City to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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