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Des Moines

$238+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
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Cheap flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$483
(Delta)

One-way from

$238
(Kiwi.com)

Popular in

November

Cheapest in

June

Average price

$721
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
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From Mexico City Benito Juarez to Des Moines
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One-way flight from Mexico City Benito Juarez to Des Moines
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Highest demand for flights based on searches. 17% potential increase in price ($120 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:45 amMEX - DSM
1 stop8h 36mUnited Airlines
Mon 12/111:26 amDSM - MEX
2 stops12h 44mUnited Airlines
Deal found 11/17$561
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:02 amMEX - DSM
1 stop7h 55mAmerican Airlines
Sat 1/315:24 amDSM - MEX
1 stop8h 16mAmerican Airlines
Deal found 11/18$576
This Aeromexico deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:00 pmMEX - DSM
2 stops24h 31mAeromexico
Sat 1/311:03 pmDSM - MEX
1 stop7h 47mAeromexico
Deal found 11/18$584
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:45 amMEX - DSM
1 stop16h 45mUnited Airlines
Sat 1/313:04 pmDSM - MEX
1 stop9h 06mUnited Airlines
Deal found 11/18$597
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:10 amMEX - DSM
1 stop11h 14mMultiple Airlines
Sun 11/3012:51 pmDSM - MEX
1 stop31h 14mMultiple Airlines
Deal found 11/17$599
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:45 pmMEX - DSM
2 stops20h 48mUnited Airlines
Sat 1/319:03 amDSM - MEX
1 stop13h 27mUnited Airlines
Deal found 11/18$608
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/233:20 pmMEX - DSM
2 stops26h 05mUnited Airlines
Sun 11/309:44 pmDSM - MEX
2 stops14h 31mUnited Airlines
Deal found 11/18$622
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:20 pmMEX - DSM
1 stop17h 55mAmerican Airlines
Sat 1/3111:35 amDSM - MEX
1 stop11h 45mAmerican Airlines
Deal found 11/18$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Mexico City

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

2:10 pm-10:31 pm

1 stop8h 21m

Des Moines

Mon 3/9

5:15 pm-10:20 am

1 stop18h 05m

$483

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

10:05 am-11:42 pm

2 stops13h 37m

Des Moines

Mon 3/9

8:00 am-5:55 pm

2 stops10h 55m

$554

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 12/21

10:00 pm-10:31 pm

2 stops24h 31m

Des Moines

Sat 1/31

6:54 am-1:40 pm

1 stop6h 46m

$584

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/22

7:05 am-10:31 pm

2 stops15h 26m

Des Moines

Sat 1/31

6:54 am-1:40 pm

1 stop6h 46m

$584

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 12/21

5:45 am-10:30 pm

1 stop16h 45m

Des Moines

Sat 1/31

3:04 pm-12:10 am

1 stop9h 06m

$597

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 12/21

2:20 pm-8:15 am

1 stop17h 55m

Des Moines

Sat 1/31

5:21 am-4:00 pm

1 stop10h 39m

$602

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/14

11:00 am-3:40 pm

1 stop28h 40m

$246

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/7

11:55 am-10:09 pm

2 stops34h 14m

$272

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/22

8:10 am-7:44 pm

1 stop11h 34m

$294

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 1/5

11:55 am-7:44 pm

1 stop7h 49m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 13 results
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Compare providers for flights from Mexico City to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Des Moines in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Mexico City-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Mexico City-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

How much does it cost to fly round-trip from Mexico City to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 8h 21m. Fly via Delta or United Airlines to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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