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Des Moines

$290+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Feb 15 — Feb 221
Sun 2/15
Sun 2/22
1 adult, Economy
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Cheap flight deals from Mexico City to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 16, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$405
(Gotogate)

One-way from

$290
(Trip.com)

Popular in

October

Cheapest in

February

Average price

$506
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
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From Mexico City Benito Juarez to Des Moines
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One-way flight from Mexico City Benito Juarez to Des Moines
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Highest demand for flights based on searches. 8% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2026.

This Gotogate deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:10 am
MEX
-
DSM
1 stop10h 09m
Frontier
Mon 2/237:17 pm
DSM
-
MEX
2 stops34h 08m
Frontier
Deal found 1/15$405
This Booking.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:55 pm
MEX
-
DSM
2 stops22h 47m
Frontier
Sat 3/78:21 pm
DSM
-
MEX
1 stop20h 44m
Frontier
Deal found 1/14$498
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:40 pm
MEX
-
DSM
2 stops18h 49m
United Airlines
Sun 5/316:45 pm
DSM
-
MEX
2 stops14h 50m
United Airlines
Deal found 1/14$509
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:35 am
MEX
-
DSM
2 stops10h 52m
United Airlines
Mon 4/271:32 pm
DSM
-
MEX
2 stops10h 38m
United Airlines
Deal found 1/15$511
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:17 pm
MEX
-
DSM
1 stop21h 09m
American Airlines
Mon 4/273:20 pm
DSM
-
MEX
1 stop20h 00m
American Airlines
Deal found 1/15$520
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:05 am
MEX
-
DSM
1 stop12h 15m
United Airlines
Wed 3/42:59 pm
DSM
-
MEX
1 stop9h 11m
United Airlines
Deal found 1/14$525
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:45 am
MEX
-
DSM
2 stops15h 56m
United Airlines
Mon 2/239:04 am
DSM
-
MEX
2 stops15h 06m
United Airlines
Deal found 1/15$547
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:05 am
MEX
-
DSM
1 stop12h 10m
United Airlines
Sat 3/76:12 am
DSM
-
MEX
1 stop17h 58m
United Airlines
Deal found 1/14$559
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/222:40 pm
MEX
-
DSM
1 stop7h 10m
United Airlines
Sun 1/253:35 pm
DSM
-
MEX
1 stop22h 00m
United Airlines
Deal found 1/13$588

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Mexico City

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 2/20

8:10 am-6:19 pm

1 stop10h 09m

Des Moines

Mon 2/23

7:17 pm-5:25 am

2 stops34h 08m

$405

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/23

4:40 pm-12:29 pm

2 stops18h 49m

Des Moines

Sun 5/31

6:45 pm-8:35 am

2 stops14h 50m

$509

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 4/21

9:35 am-9:27 pm

2 stops10h 52m

Des Moines

Mon 4/27

1:32 pm-11:10 pm

2 stops10h 38m

$511

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 4/21

1:17 pm-11:26 am

1 stop21h 09m

Des Moines

Mon 4/27

3:20 pm-10:20 am

1 stop20h 00m

$520

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 2/25

7:50 am-8:07 pm

2 stops12h 17m

Des Moines

Wed 3/4

9:04 am-12:10 am

2 stops15h 06m

$525

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 2/20

5:45 am-9:41 pm

2 stops15h 56m

Des Moines

Mon 2/23

9:04 am-12:10 am

2 stops15h 06m

$547

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 3/2

8:10 am-6:32 pm

1 stop10h 22m

$290

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/21

11:55 am-3:40 pm

1 stop27h 45m

$366

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sat 6/13

9:05 am-10:26 pm

2 stops12h 21m

$525

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Compare providers for flights from Mexico City to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Des Moines in January.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Mexico City-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Mexico City-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest month to book a flight from Mexico City to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $478). Flying from Mexico City to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Des Moines?

    There are many flights that can get you from Mexico City to Des Moines in 10h 09m. Fly via Frontier or United Airlines to get the fastest option. The distance from Mexico City to Des Moines is about 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

  • Can I find deals for business class flights from Mexico City to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $478). Flying from Mexico City to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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