$95+ Cheap flights from Mesa, AZ to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — DSM
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Des Moines are usually found in November or October, booked 65 days in advance, depart on a Wednesday or Saturday and return on a Wednesday
Cheap flight deals from Mesa to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to Des MoinesExplore the most affordable flight options available from Mesa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Mesa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:49 pm -
1 stop6h 01m
Mon 10/269:11 pm -
1 stop17h 19m
Deal found 9/10![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:23 pm -
1 stop15h 34m
Wed 10/72:42 pm -
1 stop6h 21m
Deal found 9/9![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:23 pm -
1 stop15h 34m
Mon 10/51:02 pm -
1 stop11h 45m
Deal found 9/9![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop26h 29m
Wed 11/112:45 pm -
1 stop23h 45m
Deal found 9/10![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:15 am -
1 stop11h 15m
Mon 10/198:25 pm -
1 stop13h 45m
Deal found 9/10![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:56 pm -
1 stop20h 37m
Mon 9/289:31 pm -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:20 pm -
1 stop23h 30m
Wed 10/282:42 pm -
1 stop23h 48m
Deal found 9/10![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:15 am -
1 stop11h 15m
Mon 10/128:25 pm -
1 stop13h 45m
Deal found 9/11![Frontier logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:12 pm -
2 stops19h 45m
Sun 10/1810:09 pm -
1 stop27h 09m
Deal found 9/10![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop26h 29m
Fri 10/3010:00 pm -
1 stop16h 30m
Deal found 9/11![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:12 pm -
2 stops19h 45m
Mon 10/191:47 pm -
1 stop11h 31m
Deal found 9/9![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 am -
1 stop11h 08m
Mon 9/289:31 pm -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$245
Best flights from Mesa to Des MoinesDiscover carefully curated flight deals from Mesa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Mesa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:50 pm -
Nonstop2h 40m
Tue 10/63:00 pm -
2 stops8h 30m
Deal found 9/10![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:05 pm -
1 stop8h 33m
Wed 10/217:51 pm -
1 stop5h 30m
Deal found 9/6![Delta logo]()
$475
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:20 am -
1 stop6h 00m
Tue 10/137:05 am -
2 stops7h 45m
Deal found 9/8![Southwest logo]()
$394
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:55 pm -
2 stops6h 05m
Sat 11/211:55 pm -
Nonstop3h 00m
Deal found 9/9![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:05 am -
1 stop6h 10m
Sat 10/316:20 am -
2 stops8h 30m
Deal found 9/6![Southwest logo]()
$432
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:40 am -
2 stops8h 10m
Fri 10/305:10 am -
2 stops7h 45m
Deal found 9/11![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:45 pm -
2 stops6h 25m
Tue 10/65:35 am -
2 stops8h 05m
Deal found 9/7![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:45 pm -
2 stops6h 25m
Mon 10/55:10 am -
2 stops9h 05m
Deal found 9/9![Southwest logo]()
$464
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:50 pm -
2 stops6h 55m
Sun 1/35:10 am -
2 stops8h 30m
Deal found 9/7![Southwest logo]()
$489
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop2h 40m
Sun 11/296:55 am -
Nonstop3h 05m
Deal found 9/6![Southwest logo]()
$494
Last-minute flights from Mesa to Des MoinesDiscover last-minute flight deals from Mesa to Des Moines. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Des Moines. Data last updated September 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:56 pm -
1 stop20h 37m
Mon 9/289:31 pm -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 am -
1 stop11h 08m
Mon 9/289:31 pm -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:23 pm -
1 stop15h 34m
Wed 10/72:42 pm -
1 stop6h 21m
Deal found 9/9![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:23 pm -
1 stop15h 34m
Mon 10/51:02 pm -
1 stop11h 45m
Deal found 9/9![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:15 am -
1 stop11h 15m
Mon 10/128:25 pm -
1 stop13h 45m
Deal found 9/11![Frontier logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:12 pm -
2 stops19h 45m
Sun 10/1810:09 pm -
1 stop27h 09m
Deal found 9/10![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:12 pm -
2 stops19h 45m
Mon 10/191:47 pm -
1 stop11h 31m
Deal found 9/9![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:15 am -
1 stop11h 15m
Mon 10/198:25 pm -
1 stop13h 45m
Deal found 9/10![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:20 pm -
1 stop23h 30m
Wed 10/282:42 pm -
1 stop23h 48m
Deal found 9/10![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:49 pm -
1 stop6h 01m
Mon 10/269:11 pm -
1 stop17h 19m
Deal found 9/10![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop26h 29m
Wed 11/112:45 pm -
1 stop23h 45m
Deal found 9/10![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:21 pm -
1 stop26h 29m
Fri 10/3010:00 pm -
1 stop16h 30m
Deal found 9/11![Multiple Airlines logo]()
$236
One-way flights from Mesa to Des MoinesSearch for one-way flight options from Mesa to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Mesa to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:23 pm -
1 stop15h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:39 pm -
1 stop15h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:39 pm -
1 stop15h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:34 pm -
1 stop19h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop13h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:21 pm -
1 stop17h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$123
This Super.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:59 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:39 pm -
1 stop20h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$130
Find flight deals from Mesa to Des Moines
Keep the following information in mind while searching for Mesa to Des Moines flight deals. Data was last updated September 11, 2026.
Round-trip from | $184 (Kiwi.com) |
|---|---|
One-way from | $95 (Kiwi.com) |
Popular in | August |
Cheapest in | November |
Average price | $442 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Mesa to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Wed 10/28
7:05 am-2:25 pm
1 stop5h 20m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Tue 10/27
12:55 pm-8:40 pm
1 stop5h 45m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Sat 11/7
7:00 am-4:55 pm
1 stop8h 55m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Sun 12/6
12:59 am-10:21 am
1 stop8h 22m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Tue 12/8
11:59 pm-9:50 am
1 stop8h 51m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Mon 10/5
7:05 am-2:06 pm
1 stop5h 01m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
Quickest round-trip
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Fri 10/30
1:50 pm-6:30 pm
Nonstop2h 40m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Wed 12/9
9:00 am-5:50 pm
2 stops7h 50m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Wed 10/7
7:40 am-5:50 pm
2 stops8h 10m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
PhoenixDes Moines
PHX Phoenix Sky Harbor Intl - DSM Des Moines
PHXDSM
Phoenix Sky Harbor Intl
Thu 11/26
12:59 am-10:19 am
1 stop8h 20m
Des Moines
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mesa with our price prediction graph.
PHX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Des Moines
MS9-DSM
PHX-DSM
What is the cheapest time of day to fly from MS9 to DSM?
Find hourly flight availability from Mesa to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2026.
It’s typically best to fly out from Mesa to Des Moines in the evening. Doing so could potentially save you 31% on the flight price compared to flying in the afternoon, which is usually more expensive.
Weekly flight availability from Mesa to Des Moines
Explore weekly flight availability from Mesa to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2026.
The most flights from MS9 to DSM are scheduled on a Thursday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Mesa to Des Moines?
Airfare is below average for this route at the moment.
Mesa to Des Moines flights typically cost between $369 and $542 in October.The cheapest round-trip price found within the last 5 days was $184 on Multiple Airlines (Oct 22-Oct 26).
What is the cheapest day to fly from Mesa to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Mesa to Des Moines. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Mesa to Des Moines flight should consider departing on Saturday evenings when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from Mesa to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Mesa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Top 5 airlines flying from Mesa to Des Moines
Discover the top 5 airlines that operate flights from Mesa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$249 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$142 | Average$246 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$239 | Average$411 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$263 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$318 | Average$408 | FlexibilityNo cancel fee | On-time69% |