$49+ Cheap flights from Mesa, AZ to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — DSM
Apr 6 — Apr 131
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Des Moines are usually found in November or May, booked 79 days in advance, depart on a Tuesday or Saturday and return on a Wednesday
Cheap flight deals from Mesa to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to Des MoinesExplore the most affordable flight options available from Mesa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
Explore the most affordable flight options available from Mesa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Wed 3/258:21 pm
DSM
- PHX
1 stop5h 30m
Frontier
Deal found 3/6![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:07 pm
PHX
- DSM
1 stop19h 54m
Multiple Airlines
Fri 4/242:04 pm
DSM
- PHX
1 stop8h 12m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$163
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$165
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Mon 3/234:43 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$172
This Frontier deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:50 am
PHX
- DSM
1 stop10h 24m
Frontier
Fri 4/242:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Deal found 3/4![Frontier logo]()
$180
This Super.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Fri 3/204:43 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/5![Frontier logo]()
$181
This Super.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Wed 3/258:21 pm
DSM
- PHX
1 stop5h 30m
Frontier
Deal found 3/6![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:24 pm
PHX
- DSM
1 stop13h 45m
Multiple Airlines
Mon 4/278:15 pm
DSM
- PHX
1 stop18h 40m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$185
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:15 pm
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$188
Best flights from Mesa to Des MoinesDiscover carefully curated flight deals from Mesa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
Discover carefully curated flight deals from Mesa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:35 am
PHX
- DSM
1 stop4h 40m
Southwest
Wed 4/83:15 pm
DSM
- PHX
2 stops7h 35m
Southwest
Deal found 3/3![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:46 pm
PHX
- DSM
1 stop9h 22m
Delta
Wed 5/205:28 pm
DSM
- PHX
1 stop8h 09m
Delta
Deal found 3/6![Delta logo]()
$284
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:50 pm
PHX
- DSM
1 stop8h 37m
United Airlines
Mon 6/86:50 pm
DSM
- PHX
1 stop6h 32m
United Airlines
Deal found 3/4![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:40 am
PHX
- DSM
2 stops7h 15m
Southwest
Wed 5/206:30 pm
DSM
- PHX
1 stop5h 10m
Southwest
Deal found 3/6![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:00 pm
PHX
- DSM
1 stop5h 12m
Delta
Tue 11/106:20 am
DSM
- PHX
1 stop9h 42m
Delta
Deal found 3/2![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:45 am
PHX
- DSM
1 stop8h 15m
Southwest
Mon 5/185:25 am
DSM
- PHX
1 stop7h 05m
Southwest
Deal found 3/3![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:55 pm
PHX
- DSM
Nonstop2h 40m
Southwest
Sun 4/1912:00 pm
DSM
- PHX
Nonstop3h 00m
Southwest
Deal found 3/2![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:05 pm
PHX
- DSM
2 stops7h 00m
Southwest
Sat 4/1812:05 pm
DSM
- PHX
2 stops10h 30m
Southwest
Deal found 3/4![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:25 pm
PHX
- DSM
2 stops8h 40m
Southwest
Sat 4/2512:05 pm
DSM
- PHX
2 stops7h 20m
Southwest
Deal found 3/5![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:40 am
PHX
- DSM
1 stop5h 00m
Southwest
Fri 3/277:15 pm
DSM
- PHX
2 stops6h 40m
Southwest
Deal found 3/5![Southwest logo]()
$382
Last-minute flights from Mesa to Des MoinesDiscover last-minute flight deals from Mesa to Des Moines. Data last updated March 7, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Des Moines. Data last updated March 7, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Wed 3/258:21 pm
DSM
- PHX
1 stop5h 30m
Frontier
Deal found 3/6![Frontier logo]()
$158
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Mon 3/234:43 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$172
This Super.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Fri 3/204:43 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/5![Frontier logo]()
$181
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$165
This Super.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Wed 3/258:21 pm
DSM
- PHX
1 stop5h 30m
Frontier
Deal found 3/6![Frontier logo]()
$183
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:15 pm
PHX
- DSM
Nonstop2h 41m
Frontier
Sat 3/212:56 pm
DSM
- PHX
Nonstop3h 20m
Frontier
Deal found 3/6![Frontier logo]()
$188
This Frontier deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:50 am
PHX
- DSM
1 stop10h 24m
Frontier
Fri 4/242:04 pm
DSM
- PHX
1 stop11h 38m
Frontier
Deal found 3/4![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:07 pm
PHX
- DSM
1 stop19h 54m
Multiple Airlines
Fri 4/242:04 pm
DSM
- PHX
1 stop8h 12m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:24 pm
PHX
- DSM
1 stop13h 45m
Multiple Airlines
Mon 4/278:15 pm
DSM
- PHX
1 stop18h 40m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$185
One-way flights from Mesa to Des MoinesSearch for one-way flight options from Mesa to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
Search for one-way flight options from Mesa to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:30 am
PHX
- DSM
Nonstop2h 41m
Frontier
Deal found 3/3![Frontier logo]()
$49
This Super.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1311:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Deal found 3/3![Frontier logo]()
$64
This Super.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:17 am
PHX
- DSM
Nonstop2h 41m
Frontier
Deal found 3/4![Frontier logo]()
$93
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:50 am
PHX
- DSM
1 stop8h 24m
Frontier
Deal found 3/2![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:05 pm
PHX
- DSM
1 stop25h 56m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$95
This Frontier deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:50 am
PHX
- DSM
1 stop10h 26m
Frontier
Deal found 3/2![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:15 am
PHX
- DSM
1 stop12h 58m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$107
Find flight deals from Mesa to Des Moines
Keep the following information in mind while searching for Mesa to Des Moines flight deals. Data was last updated March 7, 2026.
Round-trip from | $163 (Kiwi.com) |
|---|---|
One-way from | $49 (Frontier) |
Popular in | July |
Cheapest in | November |
Average price | $390 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
Use the filters below to find and compare flights from Mesa to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Wed 3/25
6:35 am-1:15 pm
1 stop4h 40m
Des Moines
Wed 4/8
3:15 pm-8:50 pm
2 stops7h 35m
$274
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Tue 5/12
11:46 pm-11:08 am
1 stop9h 22m
Des Moines
Wed 5/20
5:28 pm-11:37 pm
1 stop8h 09m
$284
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Tue 5/12
8:40 am-5:55 pm
2 stops7h 15m
Des Moines
Wed 5/20
6:30 pm-9:40 pm
1 stop5h 10m
$289
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Thu 4/16
2:00 pm-9:12 pm
1 stop5h 12m
Des Moines
Tue 11/10
6:20 am-3:02 pm
1 stop9h 42m
$324
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Sat 5/16
7:45 am-6:00 pm
1 stop8h 15m
Des Moines
Mon 5/18
5:25 am-10:30 am
1 stop7h 05m
$335
Quickest round-trip
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Fri 4/17
1:55 pm-6:35 pm
Nonstop2h 40m
Des Moines
Sun 4/19
12:00 pm-1:00 pm
Nonstop3h 00m
$339
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Fri 4/10
2:05 pm-11:05 pm
2 stops7h 00m
Des Moines
Sat 4/18
12:05 pm-8:35 pm
2 stops10h 30m
$353
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Mon 4/20
12:25 pm-11:05 pm
2 stops8h 40m
Des Moines
Sat 4/25
12:05 pm-5:25 pm
2 stops7h 20m
$363
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Thu 6/4
11:50 pm-10:27 am
1 stop8h 37m
Des Moines
Mon 6/8
6:50 pm-11:22 pm
1 stop6h 32m
$379
PhoenixDes Moines
PHX - DSM
PHXDSM
Phoenix Sky Harbor Intl
Thu 3/26
6:40 am-1:40 pm
1 stop5h 00m
Des Moines
Fri 3/27
7:15 pm-11:55 pm
2 stops6h 40m
$382
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Mesa to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mesa with our price prediction graph.
PHX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Des Moines
MS9-DSM
PHX-DSM
How far ahead should I book a flight from Mesa to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from Mesa to Des Moines. Price data was last updated on March 6, 2026.
The price you pay for your flight from Mesa to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 78 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Mesa to Des Moines?
Currently, July is the cheapest month in which you can book a flight from Mesa to Des Moines (average of $113). Flying from Mesa to Des Moines in February is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MS9 to DSM?
Find hourly flight availability from Mesa to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 7, 2026.
It’s typically best to fly out from Mesa to Des Moines in the evening. Doing so could potentially save you 31% on the flight price compared to flying in the morning, which is usually more expensive.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 7, 2026.
Read reviews from past customers who have flown Southwest, United Airlines, and Allegiant Air from Mesa to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Mesa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines
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Top 6 airlines flying from Mesa to Des Moines
Discover the top 6 airlines that operate flights from Mesa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$67 | Average$194 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$137 | Average$208 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$164 | Average$288 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$222 | Average$364 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$275 | Average$376 | FlexibilityNo cancel fee | On-time69% |