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Des Moines

$118+ Cheap flights from Louisiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Louisiana to Des Moines

Cheapest flights from Louisiana to Des Moines
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1210:15 am
MSY
-
DSM
1 stop12h 57m
Multiple Airlines
Mon 2/238:38 pm
DSM
-
MSY
2 stops24h 17m
Multiple Airlines
Deal found 1/26$228
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:57 pm
MSY
-
DSM
1 stop26h 15m
Multiple Airlines
Sun 2/159:00 am
DSM
-
MSY
2 stops36h 00m
Multiple Airlines
Deal found 1/27$235
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:24 pm
MSY
-
DSM
1 stop27h 50m
Multiple Airlines
Sun 4/127:00 am
DSM
-
MSY
2 stops16h 19m
Multiple Airlines
Deal found 1/28$278
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1210:15 am
MSY
-
DSM
1 stop12h 57m
Multiple Airlines
Fri 2/138:38 pm
DSM
-
MSY
2 stops24h 22m
Multiple Airlines
Deal found 1/26$279
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:38 pm
BTR
-
DSM
1 stop6h 45m
American Airlines
Sun 2/155:00 am
DSM
-
BTR
2 stops10h 57m
American Airlines
Deal found 1/27$284
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/113:30 pm
BTR
-
DSM
1 stop7h 00m
United Airlines
Sun 2/157:52 am
DSM
-
BTR
1 stop5h 26m
United Airlines
Deal found 1/27$295
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:15 am
MSY
-
DSM
2 stops16h 27m
Multiple Airlines
Sun 5/32:36 pm
DSM
-
MSY
1 stop8h 32m
Multiple Airlines
Deal found 1/28$301
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:27 pm
MSY
-
DSM
1 stop27h 24m
Multiple Airlines
Wed 3/118:21 pm
DSM
-
MSY
2 stops13h 17m
Multiple Airlines
Deal found 1/28$303
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:07 am
BTR
-
DSM
1 stop4h 41m
Delta
Mon 5/115:45 am
DSM
-
BTR
1 stop7h 02m
Delta
Deal found 1/28$304
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:45 am
MSY
-
DSM
1 stop3h 40m
Southwest
Wed 3/43:20 pm
DSM
-
MSY
1 stop4h 25m
Southwest
Deal found 1/28$317
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
LCH
-
DSM
1 stop4h 34m
American Airlines
Wed 2/2511:17 am
DSM
-
LCH
1 stop6h 40m
American Airlines
Deal found 1/27$319
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:00 am
BTR
-
DSM
2 stops8h 23m
United Airlines
Mon 5/115:17 pm
DSM
-
BTR
2 stops17h 59m
United Airlines
Deal found 1/28$522

Find flight deals from Louisiana to Des Moines

Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$228
(Kiwi.com)

One-way from

$118
(Kiwi.com)

Popular in

April

Cheapest in

August

Average price

$576
Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.
Search Deals
From Louisiana to Des Moines
Search Deals
One-way flight from Louisiana to Des Moines
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($132 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.

Fly from

Louisiana

Fly to

Des Moines

Route

Depart

Return

Price

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Thu 2/12

10:15 am-11:12 pm

1 stop12h 57m

Des Moines

Mon 2/23

8:38 pm-8:55 pm

2 stops24h 17m

$228

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Wed 2/11

8:57 pm-11:12 pm

1 stop26h 15m

Des Moines

Sun 2/15

9:00 am-9:00 pm

2 stops36h 00m

$235

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Thu 4/2

3:24 pm-7:14 pm

1 stop27h 50m

Des Moines

Sun 4/12

7:00 am-11:19 pm

2 stops16h 19m

$278

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 2/11

4:38 pm-11:23 pm

1 stop6h 45m

Des Moines

Sun 2/15

5:00 am-3:57 pm

2 stops10h 57m

$284

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Thu 2/12

10:15 am-11:12 pm

1 stop12h 57m

Des Moines

Fri 2/13

7:17 pm-2:18 pm

1 stop19h 01m

$292

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 2/11

3:30 pm-10:30 pm

1 stop7h 00m

Des Moines

Sun 2/15

7:52 am-1:18 pm

1 stop5h 26m

$295

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Wed 3/4

7:27 pm-10:51 pm

1 stop27h 24m

Des Moines

Wed 3/11

8:21 pm-9:38 am

2 stops13h 17m

$303

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 3/11

6:07 am-4:54 pm

2 stops10h 47m

Des Moines

Mon 5/11

5:45 am-12:47 pm

1 stop7h 02m

$309

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Tue 2/24

7:45 am-11:25 am

1 stop3h 40m

Des Moines

Wed 3/4

3:20 pm-7:45 pm

1 stop4h 25m

$317

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Fri 2/20

6:00 am-10:34 am

1 stop4h 34m

Des Moines

Wed 2/25

11:17 am-5:57 pm

1 stop6h 40m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 19 results
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Best time to book a flight from Louisiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Des Moines

What is the cheapest month to book a flight from Louisiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $131). Flying from Louisiana to Des Moines in December is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Louisiana?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Louisiana to Des Moines.

  • How long is the flight from Louisiana to Des Moines?

    A quick flight from Louisiana to Des Moines can take about 6h 45m. American Airlines provides one of the quickest options available for as low as $284. Louisiana and Des Moines are separated by a distance of 773 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Louisiana to Des Moines?

    While some choose either Baton Rouge Ryan - Des Moines or Lake Charles - Des Moines, New Orleans Louis Armstrong - Des Moines is the most popular route from Louisiana to Des Moines.

  • Can I find deals for flights from Louisiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Des Moines.

  • Can I find deals for business class flights from Louisiana to Des Moines?

    Yes. Cheapflights offers flight deals from Louisiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $131). Flying from Louisiana to Des Moines in December is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Louisiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Louisiana to Des Moines

Discover the top 2 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$118Average$389FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$312Average$356FlexibilityNo cancel feeOn-time63%

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