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Des Moines

$194+ Cheap flights from Louisiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Louisiana to Des Moines

Cheapest flights from Louisiana to Des Moines
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:12 pmMSY - DSM
1 stop24h 13mMultiple Airlines
Sun 11/308:55 amDSM - MSY
1 stop24h 12mMultiple Airlines
Deal found 11/1$262
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:15 amMSY - DSM
1 stop5h 13mAmerican Airlines
Wed 12/103:38 pmDSM - MSY
1 stop7h 12mAmerican Airlines
Deal found 11/1$317
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:45 amMSY - DSM
1 stop3h 40mSouthwest
Wed 12/104:15 pmDSM - MSY
2 stops6h 20mSouthwest
Deal found 11/1$322
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:25 pmMSY - DSM
1 stop13h 04mMultiple Airlines
Sun 11/308:55 amDSM - MSY
1 stop24h 12mMultiple Airlines
Deal found 11/1$328
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:27 amMSY - DSM
1 stop5h 41mAmerican Airlines
Tue 12/235:39 pmDSM - MSY
1 stop6h 47mAmerican Airlines
Deal found 11/1$336
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amMSY - DSM
1 stop5h 17mAmerican Airlines
Mon 12/294:16 pmDSM - MSY
1 stop5h 53mAmerican Airlines
Deal found 11/1$362
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:58 pmMSY - DSM
3 stops22h 05mMultiple Airlines
Tue 12/233:45 pmDSM - MSY
1 stop8h 14mMultiple Airlines
Deal found 11/1$429
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:32 amBTR - DSM
1 stop5h 15mAmerican Airlines
Sun 1/411:32 amDSM - BTR
1 stop5h 51mAmerican Airlines
Deal found 11/2$527
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:07 pmBTR - DSM
2 stops23h 58mUnited Airlines
Sun 1/46:46 pmDSM - BTR
2 stops24h 37mUnited Airlines
Deal found 11/2$608

Cheap flight deals from Louisiana to Des Moines

Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$212
(Kiwi.com)

One-way from

$194
(Delta)

Popular in

March

Cheapest in

February

Average price

$339
Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.
Search Deals
From Louisiana to Des Moines
Search Deals
One-way flight from Louisiana to Des Moines
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($80 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.

Fly from

Louisiana

Fly to

Des Moines

Route

Depart

Return

Price

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 11/21

2:12 pm-2:25 pm

1 stop24h 13m

Des Moines

Sun 11/30

8:55 am-9:07 am

1 stop24h 12m

$262

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Thu 2/19

4:08 pm-10:20 pm

1 stop6h 12m

Des Moines

Mon 2/23

8:08 am-1:18 pm

1 stop5h 10m

$319

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Thu 2/19

5:00 am-10:46 am

1 stop5h 46m

Des Moines

Mon 2/23

2:01 pm-9:25 pm

1 stop7h 24m

$319

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Wed 12/10

7:45 am-11:25 am

1 stop3h 40m

Des Moines

Wed 12/10

4:15 pm-10:35 pm

2 stops6h 20m

$322

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Sat 11/22

7:25 pm-8:29 am

1 stop13h 04m

Des Moines

Sun 11/30

8:55 am-9:07 am

1 stop24h 12m

$328

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Thu 12/18

9:27 am-3:08 pm

1 stop5h 41m

Des Moines

Tue 12/23

5:39 pm-12:26 am

1 stop6h 47m

$336

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Tue 12/23

5:30 am-10:47 am

1 stop5h 17m

Des Moines

Mon 12/29

4:16 pm-10:09 pm

1 stop5h 53m

$362

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Fri 2/20

4:20 pm-10:20 pm

1 stop6h 00m

Des Moines

Mon 2/23

8:08 am-3:37 pm

1 stop7h 29m

$364

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Fri 2/20

6:00 am-10:46 am

1 stop4h 46m

Des Moines

Mon 2/23

10:00 am-6:12 pm

2 stops8h 12m

$384

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Thu 12/18

4:58 pm-3:03 pm

3 stops22h 05m

Des Moines

Tue 12/23

3:45 pm-11:59 pm

1 stop8h 14m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 13 results
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Best time to book a flight from Louisiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Des Moines

What is the cheapest month to book a flight from Louisiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $143). Flying from Louisiana to Des Moines in March is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to DSM?

Find hourly flight availability from Louisiana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 45% on flights from Louisiana to Des Moines by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Louisiana?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Louisiana to Des Moines.

  • How long is the flight from Louisiana to Des Moines?

    A quick flight from Louisiana to Des Moines can take about 3h 40m. United Airlines provides one of the quickest options available for as low as $322. Louisiana and Des Moines are separated by a distance of 820 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Louisiana to Des Moines?

    While some choose either Baton Rouge Ryan - Des Moines or Lake Charles - Des Moines, New Orleans Louis Armstrong - Des Moines is the most popular route from Louisiana to Des Moines.

  • Can I find deals for flights from Louisiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Des Moines.

  • Can I find deals for business class flights from Louisiana to Des Moines?

    Yes. Cheapflights offers flight deals from Louisiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $143). Flying from Louisiana to Des Moines in March is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Louisiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Des Moines

Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$118Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$296Average$366FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$312Average$364FlexibilityNo cancel feeOn-time63%

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