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Des Moines

$125+ Cheap flights from Louisiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Louisiana to Des Moines

Cheapest flights from Louisiana to Des Moines
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:00 am
MSY
-
DSM
1 stop6h 30m
Southwest
Tue 6/93:45 pm
DSM
-
MSY
1 stop7h 35m
Southwest
Deal found 3/25$249
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:15 am
MSY
-
DSM
1 stop6h 31m
American Airlines
Fri 4/243:00 pm
DSM
-
MSY
1 stop6h 20m
American Airlines
Deal found 3/24$298
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:18 pm
MSY
-
DSM
1 stop26h 48m
Multiple Airlines
Sun 4/1211:00 am
DSM
-
MSY
1 stop18h 24m
Multiple Airlines
Deal found 3/24$321
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
BTR
-
DSM
1 stop5h 05m
Delta
Wed 4/222:44 pm
DSM
-
BTR
1 stop7h 12m
Delta
Deal found 3/24$326
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:00 pm
BTR
-
DSM
1 stop6h 34m
Delta
Mon 4/205:45 am
DSM
-
BTR
1 stop7h 05m
Delta
Deal found 3/24$329
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:00 am
MSY
-
DSM
1 stop6h 30m
Southwest
Thu 6/184:40 pm
DSM
-
MSY
2 stops7h 40m
Southwest
Deal found 3/25$333
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:15 am
MSY
-
DSM
1 stop8h 00m
United Airlines
Tue 5/122:58 pm
DSM
-
MSY
1 stop4h 44m
United Airlines
Deal found 3/26$353
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:08 pm
BTR
-
DSM
1 stop6h 35m
United Airlines
Sun 4/128:20 am
DSM
-
BTR
1 stop7h 13m
United Airlines
Deal found 3/24$361
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:00 pm
BTR
-
DSM
1 stop6h 38m
Delta
Mon 4/65:35 am
DSM
-
BTR
1 stop7h 16m
Delta
Deal found 3/26$399
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:53 pm
BTR
-
DSM
1 stop6h 23m
American Airlines
Sat 4/255:00 am
DSM
-
BTR
1 stop5h 02m
American Airlines
Deal found 3/24$406
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:53 pm
BTR
-
DSM
1 stop6h 23m
American Airlines
Wed 4/2211:09 am
DSM
-
BTR
2 stops10h 16m
American Airlines
Deal found 3/24$408
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 pm
LCH
-
DSM
1 stop4h 30m
United Airlines
Tue 11/38:00 am
DSM
-
LCH
1 stop5h 08m
United Airlines
Deal found 3/26$409

Find flight deals from Louisiana to Des Moines

Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Southwest)

One-way from

$125
(American Airlines)

Popular in

January

Cheapest in

August

Average price

$498
Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.
Search Deals
From Louisiana to Des Moines
Search Deals
One-way flight from Louisiana to Des Moines
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Tue 6/9

5:10 am-11:30 am

2 stops6h 20m

Des Moines

Thu 6/18

1:30 pm-10:15 pm

2 stops8h 45m

$338

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Sat 5/9

5:21 pm-10:45 pm

1 stop5h 24m

Des Moines

Tue 5/12

6:15 am-1:09 pm

1 stop6h 54m

$353

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Tue 7/28

5:00 am-11:30 am

1 stop6h 30m

Des Moines

Wed 8/5

12:30 pm-9:50 pm

1 stop9h 20m

$381

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 5/29

5:10 am-11:45 am

1 stop6h 35m

Des Moines

Sat 5/30

5:35 am-11:50 am

1 stop6h 15m

$389

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Mon 4/20

4:08 pm-10:43 pm

1 stop6h 35m

Des Moines

Sat 4/25

8:20 am-3:33 pm

1 stop7h 13m

$409

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Sat 4/18

5:00 am-4:15 pm

2 stops11h 15m

Des Moines

Mon 4/20

3:04 pm-7:37 pm

1 stop4h 33m

$414

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Tue 4/21

4:00 pm-10:34 pm

1 stop6h 34m

Des Moines

Wed 4/22

2:44 pm-9:56 pm

1 stop7h 12m

$421
Quickest round-trip

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Wed 4/8

9:30 am-2:22 pm

1 stop4h 52m

Des Moines

Sun 4/12

8:20 am-1:03 pm

1 stop4h 43m

$422

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Mon 4/20

4:08 pm-10:43 pm

1 stop6h 35m

Des Moines

Fri 4/24

3:04 pm-9:10 pm

1 stop6h 06m

$522

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Fri 5/15

6:32 pm-11:59 pm

1 stop5h 27m

Des Moines

Sun 5/17

5:00 am-10:02 am

1 stop5h 02m

$544

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Showing 1-10 of 31 resultsSorted by cheapest first
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Best time to book a flight from Louisiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Des Moines

What is the cheapest month to book a flight from Louisiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $131). Flying from Louisiana to Des Moines in January is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Louisiana to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Louisiana?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Louisiana to Des Moines.

  • How long is the flight from Louisiana to Des Moines?

    A quick flight from Louisiana to Des Moines can take about 5h 24m. Southwest provides one of the quickest options available for as low as $353. Louisiana and Des Moines are separated by a distance of 820 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Louisiana to Des Moines one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $170. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Louisiana to Des Moines for a low price.

  • What are the most popular routes from Louisiana to Des Moines?

    While some choose either Baton Rouge Ryan - Des Moines or Lake Charles - Des Moines, New Orleans Louis Armstrong - Des Moines is the most popular route from Louisiana to Des Moines.

  • Can I find deals for flights from Louisiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Des Moines.

  • Can I find deals for business class flights from Louisiana to Des Moines?

    Yes. Cheapflights offers flight deals from Louisiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $131). Flying from Louisiana to Des Moines in January is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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Alternative routes for Louisiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Des Moines

Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$244Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$290Average$431FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$312Average$386FlexibilityNo cancel feeOn-time63%

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