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Des Moines

$135+ Cheap flights from Louisiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Louisiana to Des Moines

Cheapest flights from Louisiana to Des Moines
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:34 pmBTR - DSM
1 stop8h 03mAmerican Airlines
Tue 1/64:00 pmDSM - BTR
1 stop6h 56mAmerican Airlines
Deal found 12/16$319
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:07 amBTR - DSM
1 stop7h 24mDelta
Thu 1/11:15 pmDSM - BTR
1 stop6h 33mDelta
Deal found 12/17$354
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:14 amMSY - DSM
1 stop14h 12mMultiple Airlines
Thu 1/112:00 pmDSM - MSY
1 stop25h 16mMultiple Airlines
Deal found 12/17$376
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:53 pmBTR - DSM
1 stop5h 42mAmerican Airlines
Wed 12/312:07 pmDSM - BTR
1 stop5h 50mAmerican Airlines
Deal found 12/17$379
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:48 amLCH - DSM
1 stop4h 59mAmerican Airlines
Sun 12/215:39 pmDSM - LCH
1 stop5h 00mAmerican Airlines
Deal found 12/16$394
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:32 amBTR - DSM
1 stop5h 17mAmerican Airlines
Thu 1/12:07 pmDSM - BTR
1 stop5h 50mAmerican Airlines
Deal found 12/16$394
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:11 pmBTR - DSM
2 stops9h 29mUnited Airlines
Tue 1/68:00 amDSM - BTR
2 stops7h 58mUnited Airlines
Deal found 12/17$404
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:09 amBTR - DSM
1 stop6h 52mAmerican Airlines
Sun 1/45:07 amDSM - BTR
1 stop4h 32mAmerican Airlines
Deal found 12/16$439
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/279:12 amMSY - DSM
2 stops33h 28mMultiple Airlines
Sun 1/42:56 pmDSM - MSY
1 stop23h 15mMultiple Airlines
Deal found 12/16$484
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:00 amMSY - DSM
1 stop7h 19mUnited Airlines
Fri 1/23:14 pmDSM - MSY
1 stop7h 15mUnited Airlines
Deal found 12/15$537
This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:25 pmMSY - DSM
2 stops9h 40mSouthwest
Thu 1/16:15 amDSM - MSY
2 stops8h 10mSouthwest
Deal found 12/17$633
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/271:40 pmMSY - DSM
2 stops10h 15mSouthwest
Sun 1/45:30 amDSM - MSY
2 stops10h 20mSouthwest
Deal found 12/16$638

Find flight deals from Louisiana to Des Moines

Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(Delta)

One-way from

$135
(American Airlines)

Popular in

April

Cheapest in

October

Average price

$396
Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.
Search Deals
From Louisiana to Des Moines
Search Deals
One-way flight from Louisiana to Des Moines
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($127 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.

Fly from

Louisiana

Fly to

Des Moines

Route

Depart

Return

Price

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 1/7

5:51 pm-10:29 pm

1 stop4h 38m

Des Moines

Wed 1/14

12:04 pm-10:01 pm

2 stops9h 57m

$274

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 1/7

7:07 am-4:24 pm

2 stops9h 17m

Des Moines

Wed 1/14

11:42 am-8:59 pm

2 stops9h 17m

$279

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 1/23

11:10 am-2:44 pm

1 stop27h 34m

Des Moines

Mon 1/26

11:09 am-8:21 am

2 stops21h 12m

$288

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Sat 2/14

4:08 pm-11:43 pm

2 stops7h 35m

Des Moines

Wed 2/18

8:08 am-1:18 pm

1 stop5h 10m

$324

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 1/23

5:35 pm-10:30 pm

1 stop4h 55m

Des Moines

Mon 1/26

8:10 am-1:09 pm

1 stop4h 59m

$350

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 1/23

11:14 am-7:34 pm

1 stop8h 20m

Des Moines

Mon 1/26

5:16 pm-10:02 pm

1 stop4h 46m

$350

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 1/23

7:21 am-4:24 pm

2 stops9h 03m

Des Moines

Mon 1/26

11:42 am-9:07 pm

2 stops9h 25m

$360

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Sun 12/28

3:10 pm-3:40 pm

2 stops24h 30m

Des Moines

Thu 1/1

12:00 pm-1:16 pm

1 stop25h 16m

$406

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Thu 1/1

7:10 am-2:19 pm

1 stop7h 09m

Des Moines

Mon 1/5

3:00 pm-9:18 pm

1 stop6h 18m

$419

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 12/31

10:09 am-5:01 pm

1 stop6h 52m

Des Moines

Sun 1/4

5:07 am-9:39 am

1 stop4h 32m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 24 results
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Best time to book a flight from Louisiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Des Moines

What is the cheapest month to book a flight from Louisiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $143). Flying from Louisiana to Des Moines in December is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to DSM?

Find hourly flight availability from Louisiana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 45% on flights from Louisiana to Des Moines by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Louisiana?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Louisiana to Des Moines.

  • How long is the flight from Louisiana to Des Moines?

    A quick flight from Louisiana to Des Moines can take about 4h 38m. Delta provides one of the quickest options available for as low as $274. Louisiana and Des Moines are separated by a distance of 773 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Louisiana to Des Moines?

    While some choose either New Orleans Louis Armstrong - Des Moines or Lake Charles - Des Moines, Baton Rouge Ryan - Des Moines is the most popular route from Louisiana to Des Moines.

  • Can I find deals for flights from Louisiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Des Moines.

  • Can I find deals for business class flights from Louisiana to Des Moines?

    Yes. Cheapflights offers flight deals from Louisiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $143). Flying from Louisiana to Des Moines in December is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Louisiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Des Moines

Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$194Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$296Average$431FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$312Average$356FlexibilityNo cancel feeOn-time63%

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