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Des Moines

$380+ Cheap flights from Italy to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — DSM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Italy to Des Moines

Keep the following information in mind while searching for Italy to Des Moines flight deals. Data was last updated October 30, 2025.

Round-trip from

$786
(Delta)

One-way from

$380
(Kiwi.com)
From Italy to Des Moines
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One-way flight from Italy to Des Moines
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Find flight deals from Italy to Des Moines

Cheapest flights from Italy to Des Moines
Explore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:10 amFCO - DSM
2 stops35h 23mDelta
Mon 12/16:32 pmDSM - FCO
2 stops21h 13mDelta
Deal found 10/29$786
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:05 amFCO - DSM
2 stops17h 42mMultiple Airlines
Tue 8/45:25 pmDSM - FCO
2 stops14h 25mMultiple Airlines
Deal found 10/30$861
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:05 amFCO - DSM
2 stops17h 42mKLM
Tue 8/42:15 pmDSM - FCO
1 stop12h 45mKLM
Deal found 10/30$865
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/271:30 pmFCO - DSM
2 stops29h 44mUnited Airlines
Mon 12/11:05 pmDSM - FCO
1 stop11h 40mUnited Airlines
Deal found 10/28$877
This KLM deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:40 pmFCO - DSM
1 stop34h 48mKLM
Mon 12/12:17 pmDSM - FCO
1 stop13h 13mKLM
Deal found 10/29$896
This Air Canada deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:05 amFCO - DSM
3 stops21h 27mAir Canada
Tue 8/411:30 amDSM - FCO
3 stops17h 15mAir Canada
Deal found 10/30$1,391

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.

Fly from

Italy

Fly to

Des Moines

Route

Depart

Return

Price

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 11/27

6:10 am-10:33 am

2 stops35h 23m

Des Moines

Mon 12/1

6:32 pm-10:45 pm

2 stops21h 13m

$786

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 11/13

10:05 am-8:47 pm

2 stops17h 42m

Des Moines

Tue 8/4

5:25 pm-2:50 pm

2 stops14h 25m

$861

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 11/13

10:05 am-8:47 pm

1 stop17h 42m

Des Moines

Tue 8/4

11:04 am-7:35 am

1 stop13h 31m

$872

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 11/27

1:30 pm-12:14 pm

2 stops29h 44m

Des Moines

Mon 12/1

1:05 pm-7:45 am

1 stop11h 40m

$877

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 11/27

12:40 pm-4:28 pm

1 stop34h 48m

Des Moines

Mon 12/1

2:17 pm-10:30 am

1 stop13h 13m

$896

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Fri 12/12

7:10 pm-10:46 pm

3 stops58h 36m

$399

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sun 12/14

7:10 pm-9:09 pm

3 stops32h 59m

$421

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Mon 12/15

7:10 pm-10:25 am

2 stops46h 15m

$441

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 12/18

6:00 am-12:55 pm

2 stops37h 55m

$449

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 12/13

7:10 pm-2:58 pm

3 stops50h 48m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 13 results
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Best time to book a flight from Italy to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Italy?

    For a flight from Italy to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Italy to Des Moines?

    Departing from Italy to Des Moines will take you 17h 42m. The distance between Italy and Des Moines is about 5054 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Italy to Des Moines that include hotel bookings?

    Yes. In addition to deals on Italy to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Des Moines.

  • Can I find deals for business class flights from Italy to Des Moines?

    Yes. Cheapflights offers flight deals from Italy to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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