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Des Moines

$483+ Cheap flights from Italy to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — DSM
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Italy to Des Moines

Keep the following information in mind while searching for Italy to Des Moines flight deals. Data was last updated January 12, 2026.

Round-trip from

$700
(American Airlines)

One-way from

$483
(American Airlines)
From Italy to Des Moines
Search Deals
One-way flight from Italy to Des Moines
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Find flight deals from Italy to Des Moines

Cheapest flights from Italy to Des Moines
Explore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This lol.travel deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:00 am
FCO
-
DSM
1 stop13h 25m
British Airways
Thu 4/232:18 pm
DSM
-
FCO
1 stop11h 52m
British Airways
Deal found 1/10$666
This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/297:30 am
FCO
-
DSM
2 stops20h 34m
American Airlines
Mon 2/24:25 pm
DSM
-
FCO
2 stops15h 30m
American Airlines
Deal found 1/11$700
This Air Canada deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:25 pm
FCO
-
DSM
2 stops29h 19m
Multiple Airlines
Thu 4/231:10 pm
DSM
-
FCO
3 stops17h 55m
Multiple Airlines
Deal found 1/10$1,913
This Air Canada deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:50 am
FCO
-
DSM
3 stops18h 25m
Air Canada
Thu 4/231:10 pm
DSM
-
FCO
3 stops17h 55m
Air Canada
Deal found 1/10$2,272

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.

Fly from

Italy

Fly to

Des Moines

Route

Depart

Return

Price

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 4/9

10:00 am-4:25 pm

1 stop13h 25m

Des Moines

Thu 4/23

2:18 pm-9:10 am

1 stop11h 52m

$666

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 1/29

7:30 am-11:23 pm

2 stops22h 53m

Des Moines

Mon 2/2

4:25 pm-7:35 pm

2 stops20h 10m

$700

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 4/9

12:25 pm-10:44 am

2 stops29h 19m

Des Moines

Thu 4/23

1:10 pm-2:05 pm

3 stops17h 55m

$1,913

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 4/9

6:50 am-6:15 pm

3 stops18h 25m

Des Moines

Thu 4/23

1:10 pm-2:05 pm

3 stops17h 55m

$2,272

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 4/4

2:15 pm-9:59 pm

1 stop14h 44m

$483

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 4/4

7:15 am-6:19 pm

2 stops18h 04m

$492

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sun 3/22

8:15 pm-11:40 pm

2 stops33h 25m

$622

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 6/20

7:30 am-11:54 pm

2 stops23h 24m

$652

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 6/20

9:45 am-5:42 pm

1 stop14h 57m

$954

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sun 3/22

9:05 am-4:33 pm

1 stop37h 28m

$1,486

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/10

Best time to book a flight from Italy to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Italy?

    For a flight from Italy to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Italy to Des Moines?

    Departing from Italy to Des Moines will take you 13h 25m. The distance between Italy and Des Moines is about 5054 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Italy to Des Moines that include hotel bookings?

    Yes. In addition to deals on Italy to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Des Moines.

  • Can I find deals for business class flights from Italy to Des Moines?

    Yes. Cheapflights offers flight deals from Italy to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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