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Des Moines

$64+ Cheap flights from Colorado to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — DSM
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from Colorado to Des Moines

Cheapest flights from Colorado to Des Moines
Explore the most affordable flight options available from Colorado to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:30 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 4/68:14 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/12$138
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:25 am
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 4/272:04 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/13$149
This Super.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:54 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Wed 5/62:16 pm
DSM
-
DEN
Nonstop2h 02m
Frontier
Deal found 3/13$153
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:42 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 6/158:21 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/11$154
This Super.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:30 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Fri 4/108:14 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/11$156
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:30 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 4/138:14 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/13$159
This Super.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:25 am
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 5/48:23 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 3/14$160
This Super.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:44 am
DEN
-
DSM
Nonstop1h 47m
Frontier
Wed 5/202:16 pm
DSM
-
DEN
Nonstop2h 02m
Frontier
Deal found 3/14$164
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:20 pm
GJT
-
DSM
1 stop4h 22m
United Airlines
Mon 3/305:11 pm
DSM
-
GJT
1 stop4h 48m
United Airlines
Deal found 3/11$251
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:41 am
COS
-
DSM
1 stop4h 45m
American Airlines
Mon 4/277:05 pm
DSM
-
COS
1 stop5h 27m
American Airlines
Deal found 3/12$276
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2612:08 pm
GJT
-
DSM
2 stops10h 34m
American Airlines
Mon 3/302:28 pm
DSM
-
GJT
1 stop7h 55m
American Airlines
Deal found 3/11$280
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
COS
-
DSM
1 stop6h 22m
Delta
Sat 8/155:45 am
DSM
-
COS
1 stop8h 03m
Delta
Deal found 3/15$305

Find flight deals from Colorado to Des Moines

Keep the following information in mind while searching for Colorado to Des Moines flight deals. Data was last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$138
(Frontier)

One-way from

$64
(Frontier)

Popular in

June

Cheapest in

April

Average price

$231

Good round-trip deal

$157 or less

Good one-way deal

$140 or less
Provider with most accurate pricing for Denver Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Des Moines flights.
Search Deals
From Colorado to Des Moines
Search Deals
One-way flight from Colorado to Des Moines
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Des Moines.
Search Deals
Price to beat on a one-way flight from Colorado to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Colorado to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 4/22

11:20 am-2:05 pm

Nonstop1h 45m

Des Moines

Wed 4/22

6:30 pm-7:25 pm

Nonstop1h 55m

$245

Grand JunctionDes Moines

GJT - DSM

GJTDSM

Grand Junction Regnl

Thu 3/26

6:20 pm-11:42 pm

1 stop4h 22m

Des Moines

Mon 3/30

5:11 pm-8:59 pm

1 stop4h 48m

$251

Grand JunctionDes Moines

GJT - DSM

GJTDSM

Grand Junction Regnl

Thu 3/26

12:08 pm-11:42 pm

2 stops10h 34m

Des Moines

Mon 3/30

2:28 pm-9:23 pm

1 stop7h 55m

$280

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 7/17

12:55 am-9:19 am

1 stop7h 24m

Des Moines

Wed 7/29

5:35 pm-10:29 pm

1 stop5h 54m

$285

Colorado SpringsDes Moines

COS - DSM

COSDSM

Colorado Springs

Wed 4/22

5:41 am-11:26 am

1 stop4h 45m

Des Moines

Mon 4/27

7:05 pm-11:32 pm

1 stop5h 27m

$293

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 6/10

1:10 pm-10:45 pm

2 stops8h 35m

Des Moines

Mon 6/15

4:40 pm-12:20 am

2 stops8h 40m

$295
Quickest round-trip

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 4/3

7:40 pm-10:20 pm

Nonstop1h 40m

Des Moines

Mon 4/6

7:15 pm-8:10 pm

Nonstop1h 55m

$303

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Mon 4/6

7:40 pm-10:20 pm

Nonstop1h 40m

Des Moines

Sat 4/11

5:35 am-11:55 am

1 stop7h 20m

$307

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 5/8

5:25 pm-8:16 pm

Nonstop1h 51m

Des Moines

Sun 5/10

9:06 am-10:15 am

Nonstop2h 09m

$312

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 4/29

12:35 am-9:54 am

1 stop8h 19m

Des Moines

Tue 5/5

6:10 am-3:36 pm

2 stops10h 26m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 49 resultsSorted by cheapest first
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Best time to book a flight from Colorado to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Des Moines

What is the cheapest month to book a flight from Colorado to Des Moines?

Currently, February is the cheapest month in which you can book a flight from Colorado to Des Moines (average of $58). Flying from Colorado to Des Moines in January is currently the most expensive (average of $167). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to DSM?

Find hourly flight availability from Colorado to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.

When flying from Colorado to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 46% versus a flight at noon.

What is the cheapest day to fly from Colorado to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Colorado to Des Moines. Price data was last updated on March 14, 2026.

Travelers seeking maximum savings on their Colorado to Des Moines flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Colorado to Des Moines

Explore weekly flight availability from Colorado to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 16, 2026.

The most flights from USCO to DSM are scheduled on a Monday (12 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

Related info for your journey

Find useful and relevant information for your journey from Colorado to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Colorado?

    For a flight from Colorado to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How popular is this Colorado to Des Moines flight route?

    The Colorado to Des Moines flight path was viewed by 15 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Des Moines?

    Airlines like Southwest, United Airlines, and Delta fly from Colorado to Des Moines in about 1h 45m. The time it takes to get you to your destination can typically vary by up to 5h 39m. Colorado and Des Moines are separated by a distance of 588 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to Des Moines one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $38. Users have also found prices from $68 and $83 on Southwest and American Airlines, respectively.

  • What are the most popular routes from Colorado to Des Moines?

    While some choose either Colorado Springs - Des Moines or Vail Eagle County - Des Moines, Denver Intl - Des Moines is the most popular route from Colorado to Des Moines.

  • What are the most reliable airlines from Colorado to Des Moines?

    No one likes to see their flight delayed. When booking a flight from Colorado to Des Moines consider choosing SkyWest Airlines (87%), Air Canada (85%) or United Airlines (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Colorado to Des Moines?

    While on average a flight from Colorado to Des Moines is generally $192, our data shows the cheapest flight currently is $61. When looking at the most popular route, (Denver Intl - Des Moines), you can expect to pay $223 for that flight.

  • Can I find deals for flights from Colorado to Des Moines that include hotel bookings?

    Yes. In addition to deals on Colorado to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Des Moines.

  • Can I find deals for business class flights from Colorado to Des Moines?

    Yes. Cheapflights offers flight deals from Colorado to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Des Moines?

    Currently, February is the cheapest month in which you can book a flight from Colorado to Des Moines (average of $58). Flying from Colorado to Des Moines in January is currently the most expensive (average of $167). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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Alternative routes for Colorado to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Colorado to Des Moines

Discover the top 3 airlines that operate flights from Colorado to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$61Average$160FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$137Average$294FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$149Average$414FlexibilityNo cancel feeOn-time69%

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