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Des Moines

$27+ Cheap flights from Colorado to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — DSM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Colorado to Des Moines

Cheapest flights from Colorado to Des Moines
Explore the most affordable flight options available from Colorado to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/203:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Mon 2/237:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$65
This Priceline deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:30 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 3/98:21 pm
DSM
-
DEN
Nonstop2h 05m
Frontier
Deal found 1/19$66
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Sun 2/157:27 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$82
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:36 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Mon 2/167:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$83
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:18 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 3/27:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$87
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/124:01 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Sun 2/157:27 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$104
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:49 pm
DEN
-
DSM
Nonstop1h 43m
Frontier
Mon 3/27:17 pm
DSM
-
DEN
Nonstop2h 03m
Frontier
Deal found 1/19$118
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:30 pm
DEN
-
DSM
Nonstop1h 44m
Frontier
Mon 4/138:14 pm
DSM
-
DEN
Nonstop2h 09m
Frontier
Deal found 1/19$121
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:30 pm
DEN
-
DSM
Nonstop1h 46m
Frontier
Mon 3/168:21 pm
DSM
-
DEN
Nonstop2h 05m
Frontier
Deal found 1/19$127
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:30 pm
COS
-
DSM
1 stop4h 49m
American Airlines
Tue 3/2411:17 am
DSM
-
COS
1 stop5h 43m
American Airlines
Deal found 1/20$247
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:46 pm
ASE
-
DSM
1 stop6h 54m
American Airlines
Mon 3/25:00 am
DSM
-
ASE
1 stop5h 32m
American Airlines
Deal found 1/18$249
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:30 am
COS
-
DSM
2 stops9h 10m
Southwest
Tue 3/246:40 am
DSM
-
COS
1 stop3h 50m
Southwest
Deal found 1/20$252

Find flight deals from Colorado to Des Moines

Keep the following information in mind while searching for Colorado to Des Moines flight deals. Data was last updated January 21, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$65
(Kiwi.com)

One-way from

$27
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$413

Good round-trip deal

$265 or less

Good one-way deal

$125 or less
Provider with most accurate pricing for Denver Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Des Moines flights.
Search Deals
From Colorado to Des Moines
Search Deals
One-way flight from Colorado to Des Moines
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($80 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Des Moines.
Search Deals
Price to beat on a one-way flight from Colorado to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Colorado to Des Moines that are best for you.

Fly from

Colorado

Fly to

Des Moines

Route

Depart

Return

Price

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/20

3:36 pm-6:19 pm

Nonstop1h 43m

Des Moines

Sun 2/22

7:45 pm-8:48 pm

Nonstop2h 03m

$65

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/13

3:36 pm-6:19 pm

Nonstop1h 43m

Des Moines

Sun 2/15

7:27 pm-8:30 pm

Nonstop2h 03m

$107

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/20

3:36 pm-6:19 pm

Nonstop1h 43m

Des Moines

Sun 2/22

9:00 am-8:11 am

1 stop24h 11m

$135

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Wed 4/8

6:15 pm-9:15 pm

Nonstop2h 00m

Des Moines

Thu 4/9

12:25 pm-5:15 pm

1 stop5h 50m

$177

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/13

3:36 pm-6:19 pm

Nonstop1h 43m

Des Moines

Sun 2/15

9:00 am-8:11 am

1 stop24h 11m

$187

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Thu 2/19

11:48 am-9:59 pm

1 stop9h 11m

Des Moines

Sat 2/21

2:02 pm-10:40 pm

1 stop9h 38m

$197

Colorado SpringsDes Moines

COS - DSM

COSDSM

Colorado Springs

Wed 2/18

6:55 pm-11:43 pm

1 stop3h 48m

Des Moines

Wed 2/25

2:59 pm-9:44 pm

1 stop7h 45m

$227

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/27

5:25 pm-8:07 pm

Nonstop1h 42m

Des Moines

Sat 2/28

5:03 pm-6:25 pm

Nonstop2h 22m

$229

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/20

5:30 am-3:40 pm

2 stops9h 10m

Des Moines

Sun 2/22

5:15 pm-12:23 am

1 stop8h 08m

$232

DenverDes Moines

DEN - DSM

DENDSM

Denver Intl

Fri 2/13

5:57 pm-11:40 pm

1 stop4h 43m

Des Moines

Sun 2/15

7:23 pm-11:54 pm

1 stop5h 31m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 33 results
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Best time to book a flight from Colorado to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Des Moines

What is the cheapest month to book a flight from Colorado to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Colorado to Des Moines (average of $57). Flying from Colorado to Des Moines in January is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to DSM?

Find hourly flight availability from Colorado to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.

When flying from Colorado to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 49% versus a flight at noon.

What is the cheapest day to fly from Colorado to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Colorado to Des Moines. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their Colorado to Des Moines flight should consider departing on Monday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Colorado to Des Moines

Explore weekly flight availability from Colorado to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2026.

The most flights from USCO to DSM are scheduled on a Monday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (8 on average).

Related info for your journey

Find useful and relevant information for your journey from Colorado to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Colorado?

    For a flight from Colorado to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How popular is this Colorado to Des Moines flight route?

    The Colorado to Des Moines flight path was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Des Moines?

    Airlines like Frontier, Southwest, and United Airlines fly from Colorado to Des Moines in about 1h 43m. The time it takes to get you to your destination can typically vary by up to 2h 05m. Colorado and Des Moines are separated by a distance of 588 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to Des Moines one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $37. Users have also found prices from $68 and $83 on Southwest and American Airlines, respectively.

  • What are the most popular routes from Colorado to Des Moines?

    While some choose either Colorado Springs - Des Moines or Aspen Pitkin County - Des Moines, Denver Intl - Des Moines is the most popular route from Colorado to Des Moines.

  • What are the most reliable airlines from Colorado to Des Moines?

    No one likes to see their flight delayed. When booking a flight from Colorado to Des Moines consider choosing United Airlines (89%), SkyWest Airlines (88%) or Air Canada (87%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Colorado to Des Moines?

    While on average a flight from Colorado to Des Moines is generally $237, our data shows the cheapest flight currently is $33. When looking at the most popular route, (Denver Intl - Des Moines), you can expect to pay $130 for that flight.

  • Can I find deals for flights from Colorado to Des Moines that include hotel bookings?

    Yes. In addition to deals on Colorado to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Des Moines.

  • Can I find deals for business class flights from Colorado to Des Moines?

    Yes. Cheapflights offers flight deals from Colorado to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Colorado to Des Moines (average of $57). Flying from Colorado to Des Moines in January is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Colorado to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Des Moines

Discover the top 4 airlines that operate flights from Colorado to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$55Average$155FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$137Average$297FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$139Average$397FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$176Average$298FlexibilityNo cancel feeOn-time71%

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