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Des Moines

$105+ Cheap flights from Cleveland to Des Moines (CLE - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Cleveland to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$217
(American Airlines)

One-way from

$138
(United Airlines)

Popular in

January

Cheapest in

September

Average price

$326
From Cleveland Hopkins Intl to Des Moines
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One-way flight from Cleveland Hopkins Intl to Des Moines
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Highest demand for flights based on searches. 22% potential increase in price ($123 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Cleveland to Des Moines

Cheapest flights from Cleveland to Des Moines
Explore the most affordable flight options available from Cleveland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/68:53 pmCLE - DSM
1 stop3h 30mAmerican Airlines
Wed 10/85:42 pmDSM - CLE
1 stop4h 46mAmerican Airlines
Deal found 9/10$217
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/612:08 pmCLE - DSM
1 stop5h 53mMultiple Airlines
Wed 10/82:37 pmDSM - CLE
2 stops38h 30mMultiple Airlines
Deal found 9/10$232
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:16 pmCLE - DSM
1 stop7h 57mMultiple Airlines
Sun 11/910:50 amDSM - CLE
1 stop23h 30mMultiple Airlines
Deal found 9/11$239
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:16 amCLE - DSM
1 stop6h 13mAmerican Airlines
Mon 11/243:18 pmDSM - CLE
1 stop5h 18mAmerican Airlines
Deal found 9/10$250
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:18 pmCLE - DSM
2 stops43h 14mMultiple Airlines
Sun 10/58:47 pmDSM - CLE
1 stop18h 32mMultiple Airlines
Deal found 9/11$268
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amCLE - DSM
1 stop9h 58mMultiple Airlines
Sun 11/910:50 amDSM - CLE
1 stop23h 30mMultiple Airlines
Deal found 9/11$278
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:11 pmCLE - DSM
1 stop24h 21mMultiple Airlines
Mon 9/298:25 amDSM - CLE
2 stops28h 50mMultiple Airlines
Deal found 9/10$290
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:35 pmCLE - DSM
1 stop4h 15mAmerican Airlines
Sun 11/92:16 pmDSM - CLE
1 stop7h 26mAmerican Airlines
Deal found 9/9$293
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:20 amCLE - DSM
2 stops8h 59mUnited Airlines
Mon 11/246:50 pmDSM - CLE
1 stop4h 08mUnited Airlines
Deal found 9/10$301

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Cleveland to Des Moines that are best for you.

Fly from

Cleveland

Fly to

Des Moines

Route

Depart

Return

Price

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Mon 10/6

12:08 pm-5:01 pm

1 stop5h 53m

Des Moines

Wed 10/8

2:37 pm-6:07 am

2 stops38h 30m

$232

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 11/6

1:16 pm-8:13 pm

1 stop7h 57m

Des Moines

Sun 11/9

10:50 am-11:20 am

1 stop23h 30m

$239

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 11/20

8:16 am-1:29 pm

1 stop6h 13m

Des Moines

Mon 11/24

3:18 pm-9:36 pm

1 stop5h 18m

$250

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 9/27

7:18 pm-1:32 pm

2 stops43h 14m

Des Moines

Sun 10/5

8:47 pm-4:19 pm

1 stop18h 32m

$268

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 11/7

6:00 am-2:58 pm

1 stop9h 58m

Des Moines

Sun 11/9

10:50 am-11:20 am

1 stop23h 30m

$278

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 9/25

2:11 pm-1:32 pm

1 stop24h 21m

Des Moines

Mon 9/29

8:25 am-2:15 pm

2 stops28h 50m

$290

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Fri 11/7

8:35 pm-11:50 pm

1 stop4h 15m

Des Moines

Sun 11/9

2:16 pm-10:42 pm

1 stop7h 26m

$293

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Thu 11/20

6:20 am-2:19 pm

2 stops8h 59m

Des Moines

Mon 11/24

6:50 pm-11:58 pm

1 stop4h 08m

$301

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 10/18

3:31 pm-11:16 pm

1 stop8h 45m

$105

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Sat 10/18

6:00 am-2:23 pm

2 stops9h 23m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 14 results
1
2

Best time to book a flight from Cleveland to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Des Moines

What is the cheapest month to book a flight from Cleveland to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Cleveland to Des Moines (average of $336). Flying from Cleveland to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to DSM?

Find hourly flight availability from Cleveland to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Cleveland to Des Moines in the evening. Doing so could potentially save you 27% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Cleveland to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Des Moines?

    Airlines like American Airlines fly from Cleveland to Des Moines in about 6h 13m. The time it takes to get you to your destination can typically vary by up to . There are 610 mi between Cleveland and Des Moines.

  • What are the cheapest airlines flying from Cleveland to Des Moines round-trip?

    Cheapflights users have booked flights from Cleveland to Des Moines round-trip from $271. Other airlines that can offer you cheap pricing are Delta, from $280, and United Airlines, from $286. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Cleveland to Des Moines one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $105. United Airlines flights start at $171 while deals on Delta start at $274 one-way.

  • Can I find deals for flights from Cleveland to Des Moines that include hotel bookings?

    Yes. In addition to deals on Cleveland to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Des Moines.

  • Can I find deals for business class flights from Cleveland to Des Moines?

    Yes. Cheapflights offers flight deals from Cleveland to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Cleveland to Des Moines (average of $336). Flying from Cleveland to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 4 airlines flying from Cleveland to Des Moines

Discover the top 4 airlines that operate flights from Cleveland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$271Average$396FlexibilityNo cancel feeOn-time71%
DeltaCheapest$280Average$406FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$286Average$416FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$291Average$376FlexibilityNo cancel feeOn-time63%

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