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$72+ Cheap flights from Midway (MDW) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — DSM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Midway to Des Moines

Cheapest flights from Midway to Des Moines
Explore the most affordable flight options available from Midway to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:50 pm
MDW
-
DSM
Nonstop1h 25m
Southwest
Mon 3/94:20 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 1/19$171
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:30 am
MDW
-
DSM
1 stop6h 12m
Delta
Sat 4/116:15 am
DSM
-
MDW
1 stop6h 14m
Delta
Deal found 1/20$184
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:50 pm
MDW
-
DSM
Nonstop1h 20m
Southwest
Tue 5/193:15 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 1/20$187
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:30 pm
MDW
-
DSM
1 stop4h 05m
Southwest
Mon 2/166:15 pm
DSM
-
MDW
1 stop2h 55m
Southwest
Deal found 1/20$191
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:45 pm
MDW
-
DSM
Nonstop1h 20m
Southwest
Sun 5/104:20 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 1/19$202
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:50 am
MDW
-
DSM
1 stop5h 50m
Delta
Sun 3/86:15 am
DSM
-
MDW
1 stop6h 14m
Delta
Deal found 1/21$207
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/510:05 am
MDW
-
DSM
Nonstop1h 25m
Southwest
Mon 4/134:20 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 1/20$234

Find flight deals from Midway to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$171
(Southwest)

One-way from

$72
(Southwest)

Popular in

December

Cheapest in

March

Average price

$307
Provider with most accurate pricing for Chicago Midway-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago Midway-Des Moines flights.
Search Deals
From Chicago Midway to Des Moines
Search Deals
One-way flight from Chicago Midway to Des Moines
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Des Moines that are best for you.

Fly from

Midway

Fly to

Des Moines

Route

Depart

Return

Price

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 3/5

5:40 am-1:40 pm

1 stop8h 00m

Des Moines

Mon 3/9

4:20 pm-5:40 pm

Nonstop1h 20m

$181

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 2/24

9:50 am-3:40 pm

1 stop5h 50m

Des Moines

Thu 2/26

10:40 am-5:37 pm

1 stop6h 57m

$184

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/8

9:30 am-3:42 pm

1 stop6h 12m

Des Moines

Sat 4/11

6:15 am-12:29 pm

1 stop6h 14m

$184

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 2/23

1:40 pm-10:30 pm

2 stops8h 50m

Des Moines

Thu 2/26

6:15 pm-9:10 pm

1 stop2h 55m

$196

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 2/12

5:25 am-10:55 am

2 stops5h 30m

Des Moines

Mon 2/16

5:10 am-10:35 am

1 stop5h 25m

$196

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 4/13

2:12 pm-9:08 pm

1 stop6h 56m

Des Moines

Wed 4/15

6:10 am-12:30 pm

1 stop6h 20m

$207

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Fri 3/6

9:50 am-3:40 pm

1 stop5h 50m

Des Moines

Sun 3/8

6:15 am-12:29 pm

1 stop6h 14m

$207

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sun 2/15

12:30 pm-10:15 pm

1 stop9h 45m

Des Moines

Tue 2/17

4:40 pm-7:55 pm

1 stop3h 15m

$250

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sat 3/28

9:25 pm-10:50 pm

Nonstop1h 25m

$72

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/15

10:00 am-11:25 am

Nonstop1h 25m

$79

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 20 results
1
2

Compare providers for flights from Midway to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Midway to Des Moines in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago Midway Airport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Des Moines flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Chicago Midway?

    For a flight from Chicago Midway to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 0 inbound flights from Chicago Midway per day. 0 airlines have flights to Des Moines from Chicago Midway on a regular basis.

  • How long is the flight from Chicago Midway Airport to Des Moines?

    Southwest and Delta can get you from Chicago Midway Airport to Des Moines in just under 5h 50m. Your travel time can differ by up to 2h 10m. The distance between Chicago Midway Airport and Des Moines is about 305 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Midway to Des Moines that include hotel bookings?

    Yes. In addition to deals on Midway to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Des Moines.

  • Can I find deals for business class flights from Midway to Des Moines?

    Yes. Cheapflights offers flight deals from Midway to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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