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$99+ Cheap flights from Midway (MDW) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — DSM
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Midway to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$197
(Delta)

One-way from

$99
(Delta)

Popular in

February

Cheapest in

March

Average price

$334
Provider with most accurate pricing for Chicago Midway-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Chicago Midway-Des Moines flights.
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From Chicago Midway to Des Moines
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One-way flight from Chicago Midway to Des Moines
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Highest demand for flights based on searches. 10% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Midway to Des Moines

Cheapest flights from Midway to Des Moines
Explore the most affordable flight options available from Midway to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:59 amMDW - DSM
1 stop4h 20mDelta
Sun 12/216:59 amDSM - MDW
1 stop4h 07mDelta
Deal found 11/24$209
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:44 amMDW - DSM
1 stop29h 11mMultiple Airlines
Mon 12/157:58 pmDSM - MDW
2 stops12h 48mMultiple Airlines
Deal found 11/23$232
This Southwest deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:20 amMDW - DSM
1 stop5h 05mSouthwest
Mon 12/154:15 pmDSM - MDW
1 stop4h 30mSouthwest
Deal found 11/23$254
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:34 amMDW - DSM
1 stop6h 42mDelta
Mon 12/86:17 amDSM - MDW
1 stop6h 17mDelta
Deal found 11/21$269
This Southwest deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:20 amMDW - DSM
1 stop5h 05mSouthwest
Wed 12/174:15 pmDSM - MDW
2 stops6h 20mSouthwest
Deal found 11/24$274
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:18 pmMDW - DSM
1 stop6h 45mMultiple Airlines
Fri 12/121:56 pmDSM - MDW
2 stops31h 26mMultiple Airlines
Deal found 11/23$287
This Southwest deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:05 pmMDW - DSM
2 stops7h 30mSouthwest
Sun 12/215:30 amDSM - MDW
1 stop4h 35mSouthwest
Deal found 11/24$298
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:18 pmMDW - DSM
1 stop6h 45mMultiple Airlines
Mon 12/86:35 amDSM - MDW
2 stops50h 11mMultiple Airlines
Deal found 11/21$328
This Southwest deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:20 amMDW - DSM
1 stop5h 05mSouthwest
Fri 12/54:15 pmDSM - MDW
1 stop4h 30mSouthwest
Deal found 11/24$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Des Moines that are best for you.

Fly from

Midway

Fly to

Des Moines

Route

Depart

Return

Price

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 1/7

9:50 am-3:41 pm

1 stop5h 51m

Des Moines

Wed 1/14

12:04 pm-5:34 pm

1 stop5h 30m

$197

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 1/28

9:50 am-3:41 pm

1 stop5h 51m

Des Moines

Sat 1/31

6:54 am-11:05 am

1 stop4h 11m

$203

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 12/18

9:59 am-2:19 pm

1 stop4h 20m

Des Moines

Sun 12/21

6:59 am-11:06 am

1 stop4h 07m

$209

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 12/4

7:44 am-12:55 pm

1 stop29h 11m

Des Moines

Mon 12/15

7:58 pm-8:46 am

2 stops12h 48m

$232

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 12/4

6:20 am-11:25 am

1 stop5h 05m

Des Moines

Mon 12/15

4:15 pm-8:45 pm

1 stop4h 30m

$254

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Fri 12/5

9:34 am-4:16 pm

1 stop6h 42m

Des Moines

Mon 12/8

6:17 am-12:34 pm

1 stop6h 17m

$269

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 12/15

6:20 am-11:25 am

1 stop5h 05m

Des Moines

Wed 12/17

4:15 pm-10:35 pm

2 stops6h 20m

$274

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 12/16

6:20 am-11:25 am

1 stop5h 05m

$99

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 1/21

9:50 am-3:41 pm

1 stop5h 51m

$99

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 12/17

9:34 am-4:16 pm

1 stop6h 42m

$99

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 18 results
1
2

Compare providers for flights from Midway to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Midway to Des Moines in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago Midway Airport-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Chicago Midway?

    For a flight from Chicago Midway to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 0 inbound flights from Chicago Midway per day. 0 airlines have flights to Des Moines from Chicago Midway on a regular basis.

  • How long is the flight from Chicago Midway Airport to Des Moines?

    Delta can get you from Chicago Midway Airport to Des Moines in just under 5h 51m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Des Moines is about 305 mi.

  • Can I find deals for flights from Midway to Des Moines that include hotel bookings?

    Yes. In addition to deals on Midway to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Des Moines.

  • Can I find deals for business class flights from Midway to Des Moines?

    Yes. Cheapflights offers flight deals from Midway to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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