$308+ Cheap flights from Charleston, WV to Des Moines (CRW - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — DSM
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Des Moines
Cheapest
Best
Last-minute
Cheapest flights from Charleston to Des MoinesExplore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:38 pm -
1 stop4h 31m
Tue 10/133:03 pm -
1 stop7h 27m
Deal found 9/10![Delta logo]()
$308
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:59 pm -
1 stop4h 59m
Tue 10/132:01 pm -
2 stops7h 57m
Deal found 9/10![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Sun 10/186:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Tue 10/206:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:01 am -
2 stops9h 29m
Tue 10/202:01 pm -
2 stops7h 57m
Deal found 9/13![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 pm -
1 stop6h 30m
Sat 10/311:27 am -
1 stop5h 01m
Deal found 9/14![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
1 stop4h 46m
Wed 10/288:00 am -
1 stop4h 15m
Deal found 9/10![United Airlines logo]()
$467
Best flights from Charleston to Des MoinesDiscover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:38 pm -
1 stop4h 31m
Tue 10/133:03 pm -
1 stop7h 27m
Deal found 9/10![Delta logo]()
$308
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Sun 10/186:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:05 pm -
1 stop6h 30m
Mon 10/196:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Tue 10/206:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 pm -
1 stop6h 30m
Sat 10/311:27 am -
1 stop5h 01m
Deal found 9/14![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
1 stop4h 46m
Wed 10/288:00 am -
1 stop4h 15m
Deal found 9/10![United Airlines logo]()
$467
Last-minute flights from Charleston to Des MoinesDiscover last-minute flight deals from Charleston to Des Moines. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Des Moines. Data last updated September 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:05 pm -
1 stop6h 30m
Sat 10/311:27 am -
1 stop5h 01m
Deal found 9/14![United Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:38 pm -
1 stop4h 31m
Tue 10/133:03 pm -
1 stop7h 27m
Deal found 9/10![Delta logo]()
$308
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:59 pm -
1 stop4h 59m
Tue 10/132:01 pm -
2 stops7h 57m
Deal found 9/10![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Sun 10/186:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:06 am -
1 stop5h 09m
Tue 10/206:55 pm -
1 stop4h 04m
Deal found 9/13![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:01 am -
2 stops9h 29m
Tue 10/202:01 pm -
2 stops7h 57m
Deal found 9/13![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
1 stop4h 46m
Wed 10/288:00 am -
1 stop4h 15m
Deal found 9/10![United Airlines logo]()
$467
Find flight deals from Charleston to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CRW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Fri 10/9
2:38 pm-6:09 pm
1 stop4h 31m
Des Moines
Tue 10/13
3:03 pm-11:30 pm
1 stop7h 27m
$308
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Sat 10/17
10:06 am-2:15 pm
1 stop5h 09m
Des Moines
Sun 10/18
6:55 pm-11:59 pm
1 stop4h 04m
$407
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Sat 10/17
6:05 pm-11:35 pm
1 stop6h 30m
Des Moines
Mon 10/19
6:55 pm-11:59 pm
1 stop4h 04m
$408
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Sat 10/17
10:06 am-2:15 pm
1 stop5h 09m
Des Moines
Tue 10/20
6:55 pm-11:59 pm
1 stop4h 04m
$408
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Tue 9/29
6:05 pm-11:35 pm
1 stop6h 30m
Des Moines
Sat 10/3
11:27 am-5:28 pm
1 stop5h 01m
$438
Quickest round-trip
CharlestonDes Moines
CRW Charleston Yeager - DSM Des Moines
CRWDSM
Charleston Yeager
Sat 10/24
10:29 am-2:15 pm
1 stop4h 46m
Des Moines
Wed 10/28
8:00 am-1:15 pm
1 stop4h 15m
$467
Sorted by cheapest first
Compare providers for flights from Charleston to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston, West Virginia-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston, West Virginia-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston, West Virginia-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston, West Virginia-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston, West Virginia-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
CRW-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 15, 2026.
Read reviews from past customers who have flown United Airlines from Charleston to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Comfort
7.3
Entertainment
7.1
Crew
8.1
Boarding
7.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Comfort
7.3
Entertainment
7.1
Crew
8.1
Boarding
7.7
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
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Charleston and Des Moines flights
Browse other Charleston and Des Moines flight options. Last updated on September 15, 2026.
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Top airline flying from Charleston to Des Moines
Discover the top airline that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$486 | FlexibilityNo cancel fee | On-time69% |