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Des Moines

$154+ Cheap flights from Buffalo to Des Moines (BUF - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — DSM
Aug 7 — Aug 141
Thu 8/7
Thu 8/14
1 adult, Economy
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Cheap flight deals from Buffalo to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 2, 2025.

Round-trip from

$236
(American Airlines)

One-way from

$154
(United Airlines)

Popular in

October

Cheapest in

June

Average price

$366
From Buffalo to Des Moines
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One-way flight from Buffalo to Des Moines
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Highest demand for flights based on searches. 23% potential increase in price ($134 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Buffalo to Des Moines

Cheapest flights from Buffalo to Des Moines
Explore the most affordable flight options available from Buffalo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/278:00 amBUF - DSM
1 stop5h 14mAmerican Airlines
Mon 9/13:21 pmDSM - BUF
1 stop5h 31mAmerican Airlines
Deal found 8/1$236
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/612:02 pmBUF - DSM
1 stop5h 27mDelta
Mon 9/83:12 pmDSM - BUF
1 stop7h 12mDelta
Deal found 7/30$237
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:05 amBUF - DSM
2 stops10h 08mUnited Airlines
Mon 9/13:25 pmDSM - BUF
1 stop4h 51mUnited Airlines
Deal found 8/1$311
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/294:50 pmBUF - DSM
2 stops7h 00mSouthwest
Mon 9/16:00 amDSM - BUF
2 stops12h 35mSouthwest
Deal found 7/31$504

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Buffalo to Des Moines that are best for you.

Fly from

Buffalo

Fly to

Des Moines

Route

Depart

Return

Price

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Wed 8/27

8:00 am-12:14 pm

1 stop5h 14m

Des Moines

Mon 9/1

3:21 pm-9:52 pm

1 stop5h 31m

$236

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Sat 9/6

12:02 pm-4:29 pm

1 stop5h 27m

Des Moines

Mon 9/8

3:12 pm-11:24 pm

1 stop7h 12m

$237

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Wed 8/27

7:05 am-4:13 pm

2 stops10h 08m

Des Moines

Mon 9/1

3:25 pm-9:16 pm

1 stop4h 51m

$311

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Fri 8/29

4:50 pm-10:50 pm

2 stops7h 00m

Des Moines

Mon 9/1

6:00 am-7:35 pm

2 stops12h 35m

$504

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Sun 8/24

7:05 am-10:39 am

1 stop4h 34m

$154

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Thu 8/14

6:00 am-10:38 am

1 stop5h 38m

$214

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Thu 8/14

6:00 am-2:51 pm

2 stops9h 51m

$283

BuffaloDes Moines

BUF - DSM

BUFDSM

Buffalo

Sat 8/16

9:45 am-8:20 pm

2 stops11h 35m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Buffalo to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Des Moines

What is the cheapest month to book a flight from Buffalo to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Des Moines (average of $336). Flying from Buffalo to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 2, 2025.
Read through reviews of airlines operating flights from Buffalo to Des Moines, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,983 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,904 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to Des Moines round-trip?

    American Airlines, at $236, was found to be the cheapest airline from Buffalo to Des Moines.Alternate airlines to your destination round-trip include Delta and United Airlines. You may be able to fly from Buffalo to Des Moines for 44% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Des Moines one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $154. Users have also found prices from $214 and $283 on Delta and American Airlines, respectively.

  • Can I find deals for flights from Buffalo to Des Moines that include hotel bookings?

    Yes. In addition to deals on Buffalo to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Des Moines.

  • Can I find deals for business class flights from Buffalo to Des Moines?

    Yes. Cheapflights offers flight deals from Buffalo to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Des Moines (average of $336). Flying from Buffalo to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for Buffalo to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Buffalo to Des Moines

Discover the top 3 airlines that operate flights from Buffalo to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$281Average$497FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$299Average$356FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$341Average$386FlexibilityNo cancel feeOn-time71%

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