$418+ Cheap flights from Santa Ana, CA to Columbia, MO (SNA - COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — COU
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Columbia
Cheapest
Best
Last-minute
Cheapest flights from Santa Ana to ColumbiaExplore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:45 am -
1 stop7h 34m
Wed 11/412:05 pm -
1 stop9h 05m
Deal found 9/19![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:29 am -
2 stops9h 26m
Wed 11/49:01 am -
1 stop7h 58m
Deal found 9/19![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:29 am -
2 stops9h 26m
Sat 10/1011:19 am -
1 stop9h 22m
Deal found 9/21![United Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:26 pm -
1 stop6h 27m
Fri 12/412:05 pm -
1 stop9h 05m
Deal found 9/20![American Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
1 stop7h 12m
Sat 9/265:44 am -
1 stop6h 52m
Deal found 9/22![American Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:22 pm -
1 stop6h 36m
Fri 12/411:25 am -
2 stops11h 44m
Deal found 9/23![United Airlines logo]()
$559
Best flights from Santa Ana to ColumbiaDiscover carefully curated flight deals from Santa Ana to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Santa Ana to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2711:30 am -
1 stop7h 00m
Sat 1/308:00 am -
2 stops11h 31m
Deal found 9/23![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:28 pm -
2 stops14h 27m
Tue 1/2611:30 am -
2 stops10h 49m
Deal found 9/19![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:03 pm -
2 stops14h 41m
Fri 12/411:25 am -
2 stops11h 44m
Deal found 9/23![United Airlines logo]()
$564
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:26 pm -
1 stop6h 29m
Mon 10/123:43 pm -
1 stop8h 43m
Deal found 9/24![United Airlines logo]()
$649
Last-minute flights from Santa Ana to ColumbiaDiscover last-minute flight deals from Santa Ana to Columbia. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Columbia. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
1 stop7h 12m
Sat 9/265:44 am -
1 stop6h 52m
Deal found 9/22![American Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:14 pm -
1 stop5h 58m
Wed 11/46:47 am -
1 stop9h 16m
Deal found 9/20![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:30 am -
2 stops11h 03m
Wed 11/49:01 am -
1 stop7h 58m
Deal found 9/23![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:29 am -
2 stops9h 26m
Sat 10/1011:19 am -
1 stop9h 22m
Deal found 9/21![United Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:26 pm -
1 stop6h 27m
Fri 12/412:05 pm -
1 stop9h 05m
Deal found 9/20![American Airlines logo]()
$481
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:22 pm -
1 stop6h 36m
Fri 12/411:25 am -
2 stops11h 44m
Deal found 9/23![United Airlines logo]()
$559
Find flight deals from Santa Ana to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $418 (American Airlines) |
Popular in | June |
Cheapest in | December |
Average price | $433 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaColumbia
SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional
SNACOU
Santa Ana J. Wayne/Orange Cnty
Wed 1/27
11:30 am-8:30 pm
1 stop7h 00m
Columbia Regional
Sat 1/30
8:00 am-5:31 pm
2 stops11h 31m
$464
Santa AnaColumbia
SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional
SNACOU
Santa Ana J. Wayne/Orange Cnty
Sat 1/23
6:28 pm-10:55 am
2 stops14h 27m
Columbia Regional
Tue 1/26
11:30 am-8:19 pm
2 stops10h 49m
$469
Santa AnaColumbia
SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional
SNACOU
Santa Ana J. Wayne/Orange Cnty
Fri 10/30
6:03 pm-10:44 am
2 stops14h 41m
Columbia Regional
Fri 12/4
11:25 am-9:09 pm
2 stops11h 44m
$564
Quickest round-trip
Santa AnaColumbia
SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional
SNACOU
Santa Ana J. Wayne/Orange Cnty
Sat 10/10
2:26 pm-10:55 pm
1 stop6h 29m
Columbia Regional
Mon 10/12
3:43 pm-10:26 pm
1 stop8h 43m
$649
Sorted by cheapest first
Compare providers for flights from Santa Ana to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.
SNA-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated September 24, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Boarding
7.4
Entertainment
6.8
Comfort
7.2
Overall
7.0
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Crew
7.9
Food
6.4
Boarding
7.4
Entertainment
6.8
Comfort
7.2
Overall
7.0
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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Top airline flying from Santa Ana to Columbia
Discover the top airline that operate flights from Santa Ana to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$454 | FlexibilityNo cancel fee | On-time71% |