How long is the flight from Santa Ana to Columbia, Missouri?

For as low as $462, American Airlines can have you in Columbia, Missouri from Santa Ana in 7h 53m. There are 1466 mi between Santa Ana and Columbia, Missouri.

What is the cheapest airline to fly from Santa Ana to Columbia, Missouri round-trip?

Our cheapest airline available from Santa Ana to Columbia, Missouri is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline.

What is the cheapest month to book a flight from Santa Ana to Columbia, Missouri?

Currently, January is the cheapest month in which you can book a flight from Santa Ana to Columbia, Missouri (average of $362). Flying from Santa Ana to Columbia, Missouri in March is currently the most expensive (average of $569). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Santa Ana to Columbia, Missouri?

Travelers seeking maximum savings on their Santa Ana to Columbia, Missouri flight should consider departing on Monday mornings when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Columbia, Missouri ranges from 1.9 - 5.0 inches per month. May is typically the wettest month, when rainfall can reach 5.0 in. January is typically the driest time to visit Columbia, Missouri when rainfall is around 1.9 in.

If weather is an important factor for your trip to Columbia, Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What is the cheapest day to fly round-trip from Santa Ana to Columbia, Missouri?

Users have found that leaving on a Sunday can be a cost-effective option. It’s possible to save up to 13% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Santa Ana to Columbia, Missouri?

Due to multiple factors, expect to potentially pay more when booking in September. For low rates, October can be a great choice for travel to Columbia, Missouri. Flights to Columbia, Missouri from Santa Ana in October are about $623 on average during October, but can be found for as low as $338.

What is the cheapest time of day to fly from SNA to COU?

When flying from Santa Ana to Columbia, Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?

Yes. In addition to deals on Santa Ana to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Columbia?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Columbia.

Can I find deals for business class flights from Santa Ana to Columbia?

Yes. Cheapflights offers flight deals from Santa Ana to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$357+ Cheap Flights from Santa Ana to Columbia, MO

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Santa Ana to Columbia with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Columbia

Round-trip from	$462 (American Airlines)
One-way from	$362 (United Airlines)
Popular in	September
Cheapest in	October
Average price	$471

From Santa Ana J. Wayne/Orange Cnty to Columbia Regional

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to Columbia Regional

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($67 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 11% potential price decrease ($65 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2025

Search Deals

Find flight deals from Santa Ana to Columbia

Cheapest flights from Santa Ana to Columbia
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Tue 9/26:45 amSNA - COU

1 stop7h 53mAmerican Airlines

Sat 9/612:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/18

$462

Sat 9/2711:35 amSNA - COU

1 stop6h 46mAmerican Airlines

Wed 10/14:23 pmCOU - SNA

1 stop5h 37mAmerican Airlines

Deal found 8/16

$472

Mon 8/2511:34 amSNA - COU

1 stop7h 59mAmerican Airlines

Sat 9/612:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/18

$501

Wed 9/1711:35 amSNA - COU

1 stop6h 46mAmerican Airlines

Sun 9/216:12 pmCOU - SNA

1 stop5h 42mAmerican Airlines

Deal found 8/18

$504

Thu 9/189:15 amSNA - COU

1 stop6h 27mAmerican Airlines

Sun 9/216:12 pmCOU - SNA

1 stop5h 42mAmerican Airlines

Deal found 8/18

$533

Best flights from Santa Ana to Columbia
Discover carefully curated flight deals from Santa Ana to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2025.

Tue 9/26:45 amSNA - COU

1 stop7h 53mAmerican Airlines

Sat 9/612:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/18

$462

Tue 9/306:45 amSNA - COU

1 stop7h 08mAmerican Airlines

Sat 10/412:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/15

$472

Sat 9/2711:35 amSNA - COU

1 stop6h 46mAmerican Airlines

Wed 10/14:23 pmCOU - SNA

1 stop5h 37mAmerican Airlines

Deal found 8/16

$472

Last-minute flights from Santa Ana to Columbia
Discover last-minute flight deals from Santa Ana to Columbia. Data last updated August 18, 2025 and is based on user searches.

Mon 8/2511:34 amSNA - COU

1 stop7h 59mAmerican Airlines

Sat 9/612:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/18

$501

Tue 9/26:45 amSNA - COU

1 stop7h 53mAmerican Airlines

Sat 9/612:28 pmCOU - SNA

1 stop7h 38mAmerican Airlines

Deal found 8/18

$462

Wed 9/1711:35 amSNA - COU

1 stop6h 46mAmerican Airlines

Sun 9/216:12 pmCOU - SNA

1 stop5h 42mAmerican Airlines

Deal found 8/18

$504

Thu 9/189:15 amSNA - COU

1 stop6h 27mAmerican Airlines

Sun 9/216:12 pmCOU - SNA

1 stop5h 42mAmerican Airlines

Deal found 8/18

$533

Sat 9/2711:35 amSNA - COU

1 stop6h 46mAmerican Airlines

Wed 10/14:23 pmCOU - SNA

1 stop5h 37mAmerican Airlines

Deal found 8/16

$472

One-way flights from Santa Ana to Columbia
Search for one-way flight options from Santa Ana to Columbia. Find affordable one-way fares based on user searches. Data last updated August 18, 2025.

Wed 9/241:48 pmSNA - COU

1 stop29h 39mUnited Airlines

Deal found 8/16

$357

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 9/2

6:45 am-4:38 pm

1 stop7h 53m

Columbia Regional

Sat 9/6

12:28 pm-6:06 pm

1 stop7h 38m

$462

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 9/30

6:45 am-3:53 pm

1 stop7h 08m

Columbia Regional

Sat 10/4

12:28 pm-6:06 pm

1 stop7h 38m

$472

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

11:35 am-8:21 pm

1 stop6h 46m

Columbia Regional

Wed 10/1

4:23 pm-8:00 pm

1 stop5h 37m

$472

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Wed 9/24

1:48 pm-9:27 pm

1 stop29h 39m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Santa Ana to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Columbia

Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Anonymous,Aug 2025

MIA - DCA

Related info for your journey

How long is the flight from Santa Ana to Columbia, Missouri?
For as low as $462, American Airlines can have you in Columbia, Missouri from Santa Ana in 7h 53m. There are 1466 mi between Santa Ana and Columbia, Missouri.
What is the cheapest airline to fly from Santa Ana to Columbia, Missouri round-trip?
Our cheapest airline available from Santa Ana to Columbia, Missouri is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline.
Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?
Yes. In addition to deals on Santa Ana to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Columbia?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Columbia.
Can I find deals for business class flights from Santa Ana to Columbia?
Yes. Cheapflights offers flight deals from Santa Ana to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to Columbia, Missouri?
Currently, January is the cheapest month in which you can book a flight from Santa Ana to Columbia, Missouri (average of $362). Flying from Santa Ana to Columbia, Missouri in March is currently the most expensive (average of $569). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Jefferson City

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Santa Ana to Columbia

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$392	Average$448	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$357+ Cheap flights from Santa Ana to Columbia, MO (SNA - COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Columbia with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santa Ana to Columbia

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to Columbia

Cheapest flights from Santa Ana to ColumbiaExplore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Best time to book a flight from Santa Ana to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.

Reviews of airlines servicing Columbia

Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santa Ana to Columbia, Missouri?

What is the cheapest airline to fly from Santa Ana to Columbia, Missouri round-trip?

Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?

How can I find direct flights from Santa Ana to Columbia?

Can I find deals for business class flights from Santa Ana to Columbia?

What is the cheapest month to book a flight from Santa Ana to Columbia, Missouri?

Traveling to a place near Columbia?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Columbia

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Santa Ana to Columbia

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santa Ana to Columbia
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.