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$299+ Cheap flights from Santa Ana to Columbia, MO (SNA - COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — COU
Mar 8 — Mar 151
Sun 3/8
Sun 3/15
1 adult, Economy
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Cheap flight deals from Santa Ana to Columbia

Cheapest flights from Santa Ana to Columbia
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.

This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:10 am
SNA
-
COU
1 stop7h 14m
United Airlines
Sat 2/2811:15 am
COU
-
SNA
2 stops12h 12m
United Airlines
Deal found 2/2$389
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2110:51 am
SNA
-
COU
1 stop8h 42m
United Airlines
Wed 2/253:10 pm
COU
-
SNA
1 stop9h 20m
United Airlines
Deal found 2/6$408
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:10 am
SNA
-
COU
1 stop7h 14m
United Airlines
Tue 3/39:00 am
COU
-
SNA
1 stop26h 45m
United Airlines
Deal found 2/4$501

Find flight deals from Santa Ana to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 6, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$389
(United Airlines)

One-way from

$299
(United Airlines)

Popular in

February

Cheapest in

December

Average price

$957
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($168 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Fly from

Santa Ana

Fly to

Columbia

Route

Depart

Return

Price

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

11:10 am-8:24 pm

1 stop7h 14m

Columbia Regional

Sat 2/28

11:15 am-9:27 pm

2 stops12h 12m

$389

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 2/21

10:51 am-9:33 pm

1 stop8h 42m

Columbia Regional

Wed 2/25

3:10 pm-10:30 pm

1 stop9h 20m

$408

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

11:10 am-8:24 pm

1 stop7h 14m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

  • Most accurate provider: When it comes to deals on Santa Ana-Columbia, Missouri flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Santa Ana-Columbia, Missouri flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Santa Ana-Columbia, Missouri flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana-Columbia, Missouri flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Columbia

What is the cheapest month to book a flight from Santa Ana to Columbia, Missouri?

Currently, October is the cheapest month in which you can book a flight from Santa Ana to Columbia, Missouri (average of $258). Flying from Santa Ana to Columbia, Missouri in February is currently the most expensive (average of $762). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated February 6, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,243 reviews

Boarding

7.5

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,243 reviews
American Airlines
7.2
Good
11,243 reviews

Boarding

7.5

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana to Columbia, Missouri?

    For as low as $389, United Airlines can have you in Columbia, Missouri from Santa Ana in 7h 14m. There are 1466 mi between Santa Ana and Columbia, Missouri.

  • What is the cheapest airline to fly from Santa Ana to Columbia, Missouri round-trip?

    Our cheapest airline available from Santa Ana to Columbia, Missouri is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline.

  • Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Columbia.

  • Can I find deals for business class flights from Santa Ana to Columbia?

    Yes. Cheapflights offers flight deals from Santa Ana to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Columbia, Missouri?

    Currently, October is the cheapest month in which you can book a flight from Santa Ana to Columbia, Missouri (average of $258). Flying from Santa Ana to Columbia, Missouri in February is currently the most expensive (average of $762). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

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Top airline flying from Santa Ana to Columbia

Discover the top airline that operate flights from Santa Ana to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$392Average$427FlexibilityNo cancel feeOn-time71%

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