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Columbia

$282+ Cheap flights from Santa Ana to Columbia, MO (SNA - COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — COU
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Santa Ana to Columbia

Cheapest flights from Santa Ana to Columbia
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:39 pm
SNA
-
COU
2 stops14h 16m
United Airlines
Sat 4/255:00 am
COU
-
SNA
1 stop8h 37m
United Airlines
Deal found 3/19$434
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:21 pm
SNA
-
COU
1 stop5h 42m
United Airlines
Mon 4/63:23 pm
COU
-
SNA
1 stop9h 12m
United Airlines
Deal found 3/18$443
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:45 am
SNA
-
COU
1 stop8h 22m
American Airlines
Wed 4/17:10 am
COU
-
SNA
1 stop8h 47m
American Airlines
Deal found 3/22$685
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:45 am
SNA
-
COU
1 stop8h 22m
American Airlines
Tue 3/3112:27 pm
COU
-
SNA
2 stops11h 29m
American Airlines
Deal found 3/22$691
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:45 am
SNA
-
COU
1 stop8h 22m
American Airlines
Thu 4/210:08 am
COU
-
SNA
2 stops10h 50m
American Airlines
Deal found 3/22$728

Find flight deals from Santa Ana to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$434
(United Airlines)

One-way from

$282
(United Airlines)

Popular in

April

Cheapest in

December

Average price

$409
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

6:39 pm-10:55 am

2 stops14h 16m

Columbia Regional

Sat 4/25

5:00 am-11:37 am

1 stop8h 37m

$434

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

Sat 4/18

5:00 am-2:08 pm

2 stops11h 08m

$434
Quickest round-trip

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

1:21 pm-9:03 pm

1 stop5h 42m

Columbia Regional

Mon 4/6

3:23 pm-10:35 pm

1 stop9h 12m

$443

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sun 4/5

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

Thu 4/9

3:23 pm-10:35 pm

1 stop9h 12m

$888
Cheapest one-way
Quickest one-way

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

1:21 pm-9:03 pm

1 stop5h 42m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Sorted by cheapest first

Compare providers for flights from Santa Ana to Columbia

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Columbia in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana-Columbia, Missouri flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated March 23, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,488 reviews

Comfort

7.2

Overall

7.1

Entertainment

6.9

Boarding

7.5

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,488 reviews
American Airlines
7.1
Good
11,488 reviews

Comfort

7.2

Overall

7.1

Entertainment

6.9

Boarding

7.5

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana to Columbia, Missouri?

    For as low as $434, United Airlines can have you in Columbia, Missouri from Santa Ana in 7h 53m. There are 1466 mi between Santa Ana and Columbia, Missouri.

  • What is the cheapest airline to fly from Santa Ana to Columbia, Missouri round-trip?

    Our cheapest airline available from Santa Ana to Columbia, Missouri is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline.

  • Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Columbia.

  • Can I find deals for business class flights from Santa Ana to Columbia?

    Yes. Cheapflights offers flight deals from Santa Ana to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

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Top airline flying from Santa Ana to Columbia

Discover the top airline that operate flights from Santa Ana to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$392Average$427FlexibilityNo cancel feeOn-time71%

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