HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Columbia

$242+ Cheap flights from Santa Ana, CA to Columbia, MO (SNA - COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — COU
jun. 20 — jun. 271
sáb. 6/20
sáb. 6/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to Columbia with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Columbia

Cheapest flights from Santa Ana to Columbia
Explore the most affordable flight options available from Santa Ana to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 21, 2026.

This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/199:07 am
SNA
-
COU
1 stop5h 39m
American Airlines
mié. 9/27:00 am
COU
-
SNA
1 stop7h 40m
American Airlines
Deal found 5/19$379
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/22:30 pm
SNA
-
COU
1 stop5h 45m
American Airlines
sáb. 6/66:00 am
COU
-
SNA
1 stop6h 47m
American Airlines
Deal found 5/18$388
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/2411:33 am
SNA
-
COU
1 stop7h 56m
American Airlines
lun. 6/15:19 pm
COU
-
SNA
1 stop6h 42m
American Airlines
Deal found 5/19$434
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/156:45 am
SNA
-
COU
1 stop8h 04m
American Airlines
lun. 7/205:19 pm
COU
-
SNA
1 stop7h 06m
American Airlines
Deal found 5/18$493
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/162:23 pm
SNA
-
COU
1 stop5h 57m
American Airlines
lun. 7/205:19 pm
COU
-
SNA
1 stop7h 06m
American Airlines
Deal found 5/17$512
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/106:45 am
SNA
-
COU
1 stop11h 54m
United Airlines
sáb. 8/2210:46 am
COU
-
SNA
1 stop10h 05m
United Airlines
Deal found 5/18$582

Find flight deals from Santa Ana to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mayo 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$379
(American Airlines)

One-way from

$242
(Kiwi.com)

Popular in

June

Cheapest in

December

Average price

$567
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Columbia Regional flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Columbia Regional
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($111 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 21, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar. 6/2

2:30 pm-10:15 pm

1 stop5h 45m

Columbia Regional

sáb. 6/6

6:00 am-10:47 am

1 stop6h 47m

$388

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mié. 7/15

6:45 am-4:49 pm

1 stop8h 04m

Columbia Regional

lun. 7/20

5:19 pm-10:25 pm

1 stop7h 06m

$493

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

vie. 7/10

8:45 am-8:39 pm

1 stop9h 54m

Columbia Regional

sáb. 8/22

10:46 am-6:51 pm

1 stop10h 05m

$582

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

jue. 7/16

2:10 pm-11:33 pm

1 stop7h 23m

Columbia Regional

lun. 7/20

8:00 am-9:07 am

2 stops27h 07m

$663

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

lun. 7/13

6:45 am-8:39 pm

1 stop11h 54m

Columbia Regional

lun. 8/24

3:12 pm-10:25 pm

1 stop9h 13m

$698
Cheapest one-way

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

vie. 7/17

7:54 pm-4:58 pm

2 stops19h 04m

$266

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

vie. 7/17

9:15 am-6:56 pm

1 stop7h 41m

$318

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

sáb. 6/20

7:49 pm-10:13 am

2 stops12h 24m

$369

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

lun. 6/1

10:20 am-8:39 pm

1 stop8h 19m

$418

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

sáb. 6/20

12:33 pm-10:20 pm

2 stops7h 47m

$446

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/19

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Santa Ana to Columbia

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Columbia in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Columbia, Missouri flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated mayo 21, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santa Ana to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,642 reviews

Boarding

7.5

Crew

7.9

Entertainment

6.9

Food

6.4

Overall

7.1

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,642 reviews
American Airlines
7.1
Good
11,642 reviews

Boarding

7.5

Crew

7.9

Entertainment

6.9

Food

6.4

Overall

7.1

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Columbia, Missouri?

    American Airlines and United Airlines can get you from Santa Ana, California to Columbia, Missouri in just under 5h 45m. Your travel time can differ by up to 4h 09m. Airlines will cover a distance of 1466 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santa Ana, California to Columbia, Missouri round-trip?

    Flying on American Airlines is currently your cheapest option to Columbia, Missouri, with prices starting at $392.

  • Can I find deals for flights from Santa Ana to Columbia that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Columbia.

  • Can I find deals for business class flights from Santa Ana to Columbia?

    Yes. Cheapflights offers flight deals from Santa Ana to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Columbia

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Kansas City flights
Los Angeles to St. Louis flights
San Francisco to Kansas City flights
San Francisco to St. Louis flights
Ontario to Kansas City flights
Ontario to St. Louis flights
San Diego to Kansas City flights
San Diego to St. Louis flights
Las Vegas to St. Louis flights
Las Vegas to Kansas City flights
Santa Ana to St. Louis flights
Sacramento to St. Louis flights
Santa Ana to Kansas City flights
San Jose to St. Louis flights
San Jose to Kansas City flights
Long Beach to St. Louis flights
Oakland to St. Louis flights
Oakland to Kansas City flights
Los Angeles to Springfield flights
Sacramento to Kansas City flights
Ontario to Springfield flights
Sacramento to Springfield flights
San Diego to Springfield flights
Burbank to St. Louis flights
Burbank to Kansas City flights
Santa Ana to Springfield flights
Fresno to Kansas City flights
San Francisco to Springfield flights
Las Vegas to Springfield flights
San Jose to Springfield flights
Long Beach to Kansas City flights
Fresno to Springfield flights
San Diego to Columbia flights
Palm Springs to Kansas City flights
Reno to Kansas City flights
Fresno to St. Louis flights
Burbank to Springfield flights
Bakersfield to St. Louis flights
Medford to St. Louis flights
Reno to St. Louis flights
Monterey to Kansas City flights
Los Angeles to Columbia flights
San Luis Obispo to Springfield flights
Oakland to Springfield flights
Santa Barbara to St. Louis flights
Palm Springs to St. Louis flights
Reno to Springfield flights
Los Angeles to Joplin flights

Top airline flying from Santa Ana to Columbia

Discover the top airline that operate flights from Santa Ana to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$392Average$454FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.