$566+ Cheap flights from Greenville to Columbia, MO (GSP - COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — COU
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Columbia
Cheapest
Best
Last-minute
Cheapest flights from Greenville to ColumbiaExplore the most affordable flight options available from Greenville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Greenville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:16 pm -
1 stop6h 45m
Thu 12/178:00 am -
1 stop6h 32m
Deal found 11/9![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:08 pm -
1 stop7h 34m
Wed 12/308:00 am -
1 stop6h 32m
Deal found 11/7![American Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:50 pm -
2 stops9h 37m
Wed 12/307:45 am -
2 stops10h 17m
Deal found 11/7![United Airlines logo]()
$768
Best flights from Greenville to ColumbiaDiscover carefully curated flight deals from Greenville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Greenville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:16 pm -
1 stop6h 45m
Thu 12/178:00 am -
1 stop6h 32m
Deal found 11/9![American Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:50 pm -
2 stops9h 37m
Wed 12/307:45 am -
2 stops10h 17m
Deal found 11/7![United Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2212:13 pm -
2 stops10h 25m
Wed 12/308:00 am -
1 stop6h 32m
Deal found 11/7![American Airlines logo]()
$587
Last-minute flights from Greenville to ColumbiaDiscover last-minute flight deals from Greenville to Columbia. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Columbia. Data last updated November 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:16 pm -
1 stop6h 45m
Thu 12/178:00 am -
1 stop6h 32m
Deal found 11/9![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:08 pm -
1 stop7h 34m
Wed 12/308:00 am -
1 stop6h 32m
Deal found 11/7![American Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:50 pm -
2 stops9h 37m
Wed 12/307:45 am -
2 stops10h 17m
Deal found 11/7![United Airlines logo]()
$768
Find flight deals from Greenville to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $566 (American Airlines) |
Popular in | October |
Cheapest in | December |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Greenville to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleColumbia
GSP Greenville - COU Columbia Regional
GSPCOU
Greenville
Wed 12/16
5:16 pm-11:01 pm
1 stop6h 45m
Columbia Regional
Thu 12/17
8:00 am-3:32 pm
1 stop6h 32m
$566
GreenvilleColumbia
GSP Greenville - COU Columbia Regional
GSPCOU
Greenville
Tue 12/22
12:13 pm-9:38 pm
2 stops10h 25m
Columbia Regional
Wed 12/30
8:00 am-3:32 pm
1 stop6h 32m
$587
GreenvilleColumbia
GSP Greenville - COU Columbia Regional
GSPCOU
Greenville
Tue 12/22
2:50 pm-11:27 pm
2 stops9h 37m
Columbia Regional
Wed 12/30
7:45 am-7:02 pm
2 stops10h 17m
$768
Sorted by cheapest first
Compare providers for flights from Greenville to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Columbia in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Greenville with our price prediction graph.
GSP-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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