$338+ Cheap flights from Columbia, MO to Greenville (COU - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
COU — GSP
Dec 11 — Dec 181
Round-trip
1 adult, Economy
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Find cheap flights from Columbia to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbia to GreenvilleExplore the most affordable flight options available from Columbia to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
Explore the most affordable flight options available from Columbia to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:04 pm -
1 stop4h 55m
Tue 12/155:34 pm -
1 stop6h 22m
Deal found 11/8![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:47 am -
1 stop5h 46m
Sat 11/214:35 pm -
1 stop5h 54m
Deal found 11/11![American Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:00 pm -
1 stop4h 58m
Mon 11/235:40 am -
2 stops9h 38m
Deal found 11/8![United Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:05 pm -
1 stop6h 11m
Mon 11/234:42 pm -
1 stop5h 47m
Deal found 11/8![American Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:00 pm -
1 stop4h 58m
Thu 11/265:40 am -
2 stops11h 55m
Deal found 11/6![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:01 am -
2 stops13h 46m
Fri 11/202:51 pm -
2 stops20h 54m
Deal found 11/9![United Airlines logo]()
$793
Best flights from Columbia to GreenvilleDiscover carefully curated flight deals from Columbia to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
Discover carefully curated flight deals from Columbia to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:04 pm -
1 stop4h 55m
Tue 12/155:34 pm -
1 stop6h 22m
Deal found 11/8![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/17:13 am -
1 stop5h 48m
Mon 4/53:17 pm -
1 stop7h 33m
Deal found 11/10![American Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:00 pm -
1 stop4h 58m
Thu 11/265:40 am -
2 stops11h 55m
Deal found 11/6![United Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:16 pm -
1 stop15h 59m
Sun 4/47:03 am -
1 stop11h 43m
Deal found 11/7![American Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/111:15 am -
1 stop4h 45m
Sun 4/46:30 am -
1 stop4h 59m
Deal found 11/10![United Airlines logo]()
$697
Last-minute flights from Columbia to GreenvilleDiscover last-minute flight deals from Columbia to Greenville. Data last updated November 11, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to Greenville. Data last updated November 11, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:01 am -
2 stops13h 46m
Fri 11/202:51 pm -
2 stops20h 54m
Deal found 11/9![United Airlines logo]()
$793
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:00 pm -
1 stop4h 58m
Mon 11/235:40 am -
2 stops9h 38m
Deal found 11/8![United Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:05 pm -
1 stop6h 11m
Mon 11/234:42 pm -
1 stop5h 47m
Deal found 11/8![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:47 am -
1 stop5h 46m
Sat 11/214:35 pm -
1 stop5h 54m
Deal found 11/11![American Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:00 pm -
1 stop4h 58m
Thu 11/265:40 am -
2 stops11h 55m
Deal found 11/6![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:04 pm -
1 stop4h 55m
Tue 12/155:34 pm -
1 stop6h 22m
Deal found 11/8![United Airlines logo]()
$338
One-way flights from Columbia to GreenvilleSearch for one-way flight options from Columbia to Greenville. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
Search for one-way flight options from Columbia to Greenville. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:04 pm -
3 stops59h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:00 pm -
1 stop4h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:05 pm -
2 stops8h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:05 pm -
1 stop6h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![American Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:00 am -
2 stops10h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$823
Find flight deals from Columbia to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $338 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
Use the filters below to find and compare flights from Columbia to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Tue 12/8
3:04 pm-8:59 pm
1 stop4h 55m
Greenville
Tue 12/15
5:34 pm-10:56 pm
1 stop6h 22m
$338
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Fri 11/20
8:04 pm-8:13 am
3 stops59h 09m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$390
Quickest round-trip
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Sat 11/21
3:00 pm-8:58 pm
1 stop4h 58m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$428
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Fri 11/20
12:05 pm-7:14 pm
1 stop6h 09m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$554
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Thu 4/1
7:13 am-2:01 pm
1 stop5h 48m
Greenville
Mon 4/5
3:17 pm-9:50 pm
1 stop7h 33m
$631
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Sun 11/22
3:00 pm-8:58 pm
1 stop4h 58m
Greenville
Thu 11/26
5:40 am-4:35 pm
2 stops11h 55m
$668
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Thu 4/1
11:15 am-5:00 pm
1 stop4h 45m
Greenville
Sun 4/4
6:30 am-10:29 am
1 stop4h 59m
$697
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Thu 4/1
6:16 pm-11:15 am
1 stop15h 59m
Greenville
Sun 4/4
7:03 am-5:46 pm
1 stop11h 43m
$721
ColumbiaGreenville
COU Columbia Regional - GSP Greenville
COUGSP
Columbia Regional
Fri 11/20
8:00 am-7:01 pm
2 stops10h 01m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$823
Sorted by cheapest first
Compare providers for flights from Columbia to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Greenville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbia, Missouri-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbia, Missouri-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbia to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Columbia with our price prediction graph.
COU-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 11, 2026.
Read reviews from past customers who have flown American Airlines from Columbia to Greenville. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Boarding
7.4
Entertainment
6.8
Overall
7.0
Comfort
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Boarding
7.4
Entertainment
6.8
Overall
7.0
Comfort
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Columbia to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 11, 2026.
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Other flights from Columbia
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Columbia to Greenville
Discover the top airline that operate flights from Columbia to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$443 | FlexibilityNo cancel fee | On-time71% |