$267+ Cheap flights from Columbia, MO (COU) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
COU — CHS
Dec 8 — Dec 151
Round-trip
1 adult, Economy
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Find cheap flights from Columbia to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to South Carolina
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Cheapest flights from Columbia to South CarolinaExplore the most affordable flight options available from Columbia to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2026.
Explore the most affordable flight options available from Columbia to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2026.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop4h 39m
Fri 1/14:11 pm -
1 stop6h 27m
Deal found 11/3![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
1 stop6h 49m
Mon 12/285:37 pm -
1 stop6h 05m
Deal found 11/6![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:26 pm -
1 stop4h 29m
Sat 11/215:08 pm -
1 stop5h 35m
Deal found 11/4![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:27 am -
1 stop6h 37m
Thu 11/124:14 pm -
1 stop7h 01m
Deal found 11/3![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:25 am -
2 stops11h 34m
Sat 12/196:39 pm -
1 stop5h 48m
Deal found 11/5![United Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
1 stop6h 49m
Sun 12/274:10 pm -
1 stop6h 28m
Deal found 11/3![American Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:47 am -
1 stop6h 52m
Sun 11/224:59 pm -
1 stop6h 45m
Deal found 11/3![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:20 am -
1 stop5h 46m
Thu 11/127:00 am -
2 stops14h 41m
Deal found 11/3![United Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:11 pm -
1 stop5h 14m
Sun 11/225:53 am -
1 stop5h 11m
Deal found 11/4![American Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:00 am -
2 stops8h 51m
Tue 12/811:30 am -
2 stops12h 26m
Deal found 11/5![United Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:14 am -
1 stop5h 48m
Thu 11/269:35 am -
1 stop6h 00m
Deal found 11/6![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:26 am -
1 stop14h 33m
Sun 11/225:17 pm -
1 stop5h 26m
Deal found 11/4![American Airlines logo]()
$616
Best flights from Columbia to South CarolinaDiscover carefully curated flight deals from Columbia to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 8, 2026.
Discover carefully curated flight deals from Columbia to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 8, 2026.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop4h 39m
Fri 1/14:11 pm -
1 stop6h 27m
Deal found 11/3![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/87:45 am -
1 stop5h 01m
Tue 1/129:45 am -
1 stop5h 52m
Deal found 11/3![United Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:14 am -
1 stop4h 15m
Fri 1/157:21 pm -
1 stop4h 39m
Deal found 11/6![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:25 am -
2 stops11h 34m
Sat 12/196:39 pm -
1 stop5h 48m
Deal found 11/5![United Airlines logo]()
$435
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/237:45 am -
1 stop5h 01m
Wed 1/279:45 am -
1 stop5h 52m
Deal found 11/7![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:45 am -
2 stops9h 03m
Wed 2/311:27 am -
2 stops13h 03m
Deal found 11/3![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 am -
2 stops9h 40m
Sun 11/224:11 pm -
1 stop7h 33m
Deal found 11/4![American Airlines logo]()
$588
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/17:13 am -
1 stop4h 01m
Mon 4/55:12 pm -
1 stop5h 38m
Deal found 11/3![American Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:00 am -
2 stops8h 51m
Tue 12/811:30 am -
2 stops12h 26m
Deal found 11/5![United Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/137:03 am -
2 stops10h 54m
Thu 3/189:11 am -
2 stops8h 54m
Deal found 11/4![American Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:00 pm -
1 stop4h 58m
Thu 11/265:40 am -
2 stops11h 55m
Deal found 11/6![United Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:16 pm -
1 stop15h 59m
Sun 4/47:03 am -
1 stop11h 43m
Deal found 11/4![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:26 am -
2 stops12h 32m
Mon 11/2312:00 pm -
2 stops10h 29m
Deal found 11/4![American Airlines logo]()
$852
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/138:00 am -
2 stops7h 49m
Thu 3/1810:34 am -
3 stops13h 19m
Deal found 11/4![United Airlines logo]()
$1,278
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:00 am -
2 stops8h 11m
Mon 11/2311:27 am -
3 stops12h 31m
Deal found 11/4![United Airlines logo]()
$1,541
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:00 pm -
3 stops17h 59m
Sun 11/2210:16 am -
2 stops13h 42m
Deal found 11/4![United Airlines logo]()
$2,206
Last-minute flights from Columbia to South CarolinaDiscover last-minute flight deals from Columbia to South Carolina. Data last updated November 8, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to South Carolina. Data last updated November 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:27 am -
1 stop6h 37m
Thu 11/124:14 pm -
1 stop7h 01m
Deal found 11/3![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:20 am -
1 stop5h 46m
Thu 11/127:00 am -
2 stops14h 41m
Deal found 11/3![United Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:26 pm -
1 stop4h 29m
Sat 11/215:08 pm -
1 stop5h 35m
Deal found 11/4![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:47 am -
1 stop6h 52m
Sun 11/224:59 pm -
1 stop6h 45m
Deal found 11/3![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:11 pm -
1 stop5h 14m
Sun 11/225:53 am -
1 stop5h 11m
Deal found 11/4![American Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:26 am -
1 stop14h 33m
Sun 11/225:17 pm -
1 stop5h 26m
Deal found 11/4![American Airlines logo]()
$616
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:14 am -
1 stop5h 48m
Thu 11/269:35 am -
1 stop6h 00m
Deal found 11/6![American Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:00 am -
2 stops8h 51m
Tue 12/811:30 am -
2 stops12h 26m
Deal found 11/5![United Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:25 am -
2 stops11h 34m
Sat 12/196:39 pm -
1 stop5h 48m
Deal found 11/5![United Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
1 stop6h 49m
Mon 12/285:37 pm -
1 stop6h 05m
Deal found 11/6![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
1 stop6h 49m
Sun 12/274:10 pm -
1 stop6h 28m
Deal found 11/3![American Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop4h 39m
Fri 1/14:11 pm -
1 stop6h 27m
Deal found 11/3![American Airlines logo]()
$328
One-way flights from Columbia to South CarolinaSearch for one-way flight options from Columbia to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 8, 2026.
Search for one-way flight options from Columbia to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 8, 2026.
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sun 12/208:00 am -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:26 am -
1 stop7h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![American Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:14 am -
1 stop4h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$283
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:45 am -
2 stops10h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:53 pm -
3 stops43h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:35 am -
3 stops46h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:00 pm -
2 stops23h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![United Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:14 am -
1 stop3h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$703
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:00 am -
2 stops10h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$930
Find flight deals from Columbia to South Carolina
Keep the following information in mind while searching for Columbia to South Carolina flight deals. Data was last updated November 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $328 (American Airlines) |
One-way from | $267 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 8, 2026.
Use the filters below to find and compare flights from Columbia to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Sun 12/20
8:00 am-1:39 pm
1 stop4h 39m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$267
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Mon 11/30
6:26 am-3:20 pm
1 stop7h 54m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$283
ColumbiaColumbia
COU Columbia Regional - CAE Columbia Metropolitan
COUCAE
Columbia Regional
Mon 2/1
8:14 am-1:17 pm
1 stop4h 03m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$283
ColumbiaColumbia
COU Columbia Regional - CAE Columbia Metropolitan
COUCAE
Columbia Regional
Mon 2/1
7:45 am-7:24 pm
2 stops10h 39m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$289
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Fri 12/25
8:00 am-1:39 pm
1 stop4h 39m
Charleston
Fri 1/1
4:11 pm-9:38 pm
1 stop6h 27m
$328
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Sat 1/9
8:14 am-1:29 pm
1 stop4h 15m
Charleston
Fri 1/15
7:21 pm-11:00 pm
1 stop4h 39m
$338
ColumbiaMyrtle Beach
COU Columbia Regional - MYR Myrtle Beach Intl
COUMYR
Columbia Regional
Sun 11/29
10:35 am-9:55 am
3 stops46h 20m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$370
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Fri 1/8
7:45 am-1:46 pm
1 stop5h 01m
Charleston
Tue 1/12
9:45 am-2:37 pm
1 stop5h 52m
$428
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Tue 12/15
11:25 am-11:59 pm
2 stops11h 34m
Charleston
Sat 12/19
6:39 pm-11:27 pm
1 stop5h 48m
$435
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Sat 1/23
7:45 am-1:46 pm
1 stop5h 01m
Charleston
Wed 1/27
9:45 am-2:37 pm
1 stop5h 52m
$438
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from Columbia to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Columbia with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbia to South Carolina
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What is the cheapest month to book a flight from Columbia, Missouri to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to South Carolina (average of $258). Flying from Columbia, Missouri to South Carolina in October is currently the most expensive (average of $632). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbia, Missouri to South Carolina?
Airfare is below average for this route at the moment.
Columbia, Missouri to South Carolina flights typically cost between $378 and $518 in December.The cheapest round-trip price found within the last 5 days was $328 on American Airlines (Dec 25-Jan 1).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 8, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Entertainment
7.1
Overall
7.3
Crew
8.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Columbia to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbia to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbia to South Carolina by cabin class
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Columbia and South Carolina flights
Browse other Columbia and South Carolina flight options. Last updated on November 8, 2026.
Popular flight searches
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Columbia to South Carolina flights
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Top 2 airlines flying from Columbia to South Carolina
Discover the top 2 airlines that operate flights from Columbia to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$536 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$447 | FlexibilityNo cancel fee | On-time71% |