$168+ Cheap flights from Panama City, FL (ECP) to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHI
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Chicago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to ChicagoExplore the most affordable flight options available from Panama City to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from Panama City to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Tue 7/2112:09 pm
ORD
- ECP
Nonstop2h 33m
American Airlines
Deal found 6/15![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:25 am
ECP
- ORD
Nonstop2h 44m
United Airlines
Tue 12/17:00 am
ORD
- ECP
Nonstop2h 37m
United Airlines
Deal found 6/16![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Wed 7/225:07 am
ORD
- ECP
1 stop5h 20m
American Airlines
Deal found 6/17![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:45 pm
ECP
- MDW
Nonstop2h 10m
Southwest
Sat 9/57:45 am
MDW
- ECP
Nonstop2h 10m
Southwest
Deal found 6/17![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:09 pm
ECP
- ORD
Nonstop2h 59m
American Airlines
Sat 9/55:05 am
ORD
- ECP
1 stop5h 29m
American Airlines
Deal found 6/17![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:38 am
ECP
- MDW
1 stop4h 37m
Delta
Tue 7/146:00 am
MDW
- ECP
1 stop6h 31m
Delta
Deal found 6/15![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:47 pm
ECP
- ORD
Nonstop2h 42m
United Airlines
Sun 9/610:33 am
ORD
- ECP
Nonstop2h 33m
United Airlines
Deal found 6/16![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:00 am
ECP
- MDW
Nonstop2h 15m
Southwest
Sun 9/66:15 pm
MDW
- ECP
Nonstop2h 10m
Southwest
Deal found 6/16![Southwest logo]()
$357
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:40 am
ECP
- MDW
2 stops8h 40m
Southwest
Wed 7/221:55 pm
MDW
- ECP
1 stop8h 15m
Southwest
Deal found 6/17![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ECP
- MDW
1 stop4h 09m
Delta
Tue 8/1112:46 pm
MDW
- ECP
1 stop5h 49m
Delta
Deal found 6/13![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:40 am
ECP
- MDW
2 stops7h 30m
Southwest
Wed 7/1512:05 pm
MDW
- ECP
2 stops7h 40m
Southwest
Deal found 6/13![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:09 pm
ECP
- ORD
Nonstop2h 59m
American Airlines
Mon 8/2411:59 am
ORD
- ECP
Nonstop2h 31m
American Airlines
Deal found 6/18![American Airlines logo]()
$367
Best flights from Panama City to ChicagoDiscover carefully curated flight deals from Panama City to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from Panama City to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:40 am
ECP
- MDW
2 stops8h 40m
Southwest
Wed 7/221:55 pm
MDW
- ECP
1 stop8h 15m
Southwest
Deal found 6/15![Southwest logo]()
$360
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:05 pm
ECP
- ORD
Nonstop2h 45m
United Airlines
Thu 8/1310:33 am
ORD
- ECP
Nonstop2h 33m
United Airlines
Deal found 6/17![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:19 am
ECP
- ORD
1 stop5h 11m
Delta
Mon 9/146:25 pm
ORD
- ECP
1 stop4h 50m
Delta
Deal found 6/17![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:20 pm
ECP
- MDW
2 stops7h 50m
Southwest
Sat 8/17:55 am
MDW
- ECP
1 stop6h 30m
Southwest
Deal found 6/13![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:23 am
ECP
- MDW
1 stop6h 02m
Delta
Mon 9/145:10 pm
MDW
- ECP
1 stop6h 05m
Delta
Deal found 6/17![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:47 pm
ECP
- ORD
Nonstop2h 42m
United Airlines
Fri 9/1110:40 am
ORD
- ECP
Nonstop2h 33m
United Airlines
Deal found 6/13![United Airlines logo]()
$398
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:30 pm
ECP
- MDW
1 stop5h 10m
Southwest
Thu 7/308:40 am
MDW
- ECP
Nonstop2h 10m
Southwest
Deal found 6/17![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:35 am
ECP
- MDW
1 stop4h 16m
Delta
Mon 8/2412:46 pm
MDW
- ECP
1 stop5h 10m
Delta
Deal found 6/15![Delta logo]()
$387
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:05 pm
ECP
- ORD
1 stop7h 40m
United Airlines
Wed 7/17:05 am
ORD
- ECP
Nonstop2h 39m
United Airlines
Deal found 6/13![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:00 am
ECP
- MDW
Nonstop2h 15m
Southwest
Sun 8/162:15 pm
MDW
- ECP
Nonstop2h 05m
Southwest
Deal found 6/17![Southwest logo]()
$384
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:10 pm
ECP
- MDW
1 stop6h 26m
Delta
Mon 8/175:10 pm
MDW
- ECP
1 stop6h 20m
Delta
Deal found 6/16![Delta logo]()
$404
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:20 pm
ECP
- MDW
Nonstop2h 15m
Southwest
Sat 8/87:45 am
MDW
- ECP
Nonstop2h 10m
Southwest
Deal found 6/14![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:25 am
ECP
- ORD
Nonstop2h 44m
United Airlines
Sun 8/97:05 am
ORD
- ECP
Nonstop2h 39m
United Airlines
Deal found 6/15![United Airlines logo]()
$448
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:10 am
ECP
- MDW
Nonstop2h 15m
Southwest
Sun 7/2611:35 am
MDW
- ECP
Nonstop2h 05m
Southwest
Deal found 6/17![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:05 pm
ECP
- ORD
Nonstop2h 45m
United Airlines
Sun 7/127:05 am
ORD
- ECP
Nonstop2h 39m
United Airlines
Deal found 6/16![United Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:08 pm
ECP
- ORD
1 stop6h 51m
Delta
Thu 6/256:35 am
ORD
- ECP
1 stop5h 51m
Delta
Deal found 6/13![Delta logo]()
$493
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:30 am
ECP
- ORD
1 stop8h 21m
United Airlines
Thu 7/3010:47 am
ORD
- ECP
Nonstop2h 37m
United Airlines
Deal found 6/17![United Airlines logo]()
$471
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:08 pm
ECP
- ORD
1 stop6h 51m
Delta
Fri 6/265:30 am
ORD
- ECP
1 stop5h 24m
Delta
Deal found 6/13![Delta logo]()
$493
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:05 pm
ECP
- ORD
Nonstop2h 45m
United Airlines
Sun 7/510:47 am
ORD
- ECP
Nonstop2h 37m
United Airlines
Deal found 6/16![United Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:00 am
ECP
- ORD
1 stop4h 13m
Delta
Sat 6/275:30 am
ORD
- ECP
1 stop5h 24m
Delta
Deal found 6/13![Delta logo]()
$504
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:25 am
ECP
- ORD
Nonstop2h 44m
United Airlines
Sat 7/187:05 am
ORD
- ECP
Nonstop2h 39m
United Airlines
Deal found 6/15![United Airlines logo]()
$485
Last-minute flights from Panama City to ChicagoDiscover last-minute flight deals from Panama City to Chicago. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Chicago. Data last updated June 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ECP
- MDW
1 stop4h 09m
Delta
Tue 8/1112:46 pm
MDW
- ECP
1 stop5h 49m
Delta
Deal found 6/13![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ECP
- MDW
1 stop4h 09m
Delta
Sat 8/84:39 pm
MDW
- ECP
1 stop5h 01m
Delta
Deal found 6/13![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ECP
- MDW
1 stop4h 09m
Delta
Mon 8/106:05 am
MDW
- ECP
1 stop6h 43m
Delta
Deal found 6/13![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:38 am
ECP
- MDW
1 stop4h 37m
Delta
Tue 7/146:00 am
MDW
- ECP
1 stop6h 31m
Delta
Deal found 6/15![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Wed 7/1512:09 pm
ORD
- ECP
Nonstop2h 33m
American Airlines
Deal found 6/15![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:40 am
ECP
- MDW
2 stops7h 30m
Southwest
Wed 7/1512:05 pm
MDW
- ECP
2 stops7h 40m
Southwest
Deal found 6/13![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Tue 7/2112:09 pm
ORD
- ECP
Nonstop2h 33m
American Airlines
Deal found 6/15![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Wed 7/225:07 am
ORD
- ECP
1 stop5h 20m
American Airlines
Deal found 6/17![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:40 am
ECP
- MDW
2 stops8h 40m
Southwest
Wed 7/221:55 pm
MDW
- ECP
1 stop8h 15m
Southwest
Deal found 6/17![Southwest logo]()
$360
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:27 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Tue 7/2112:09 pm
ORD
- ECP
Nonstop2h 33m
American Airlines
Deal found 6/15![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:54 pm
ECP
- ORD
1 stop5h 07m
American Airlines
Sat 8/14:45 pm
ORD
- ECP
1 stop6h 52m
American Airlines
Deal found 6/13![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:17 pm
ECP
- ORD
Nonstop3h 02m
American Airlines
Sat 8/14:45 pm
ORD
- ECP
1 stop6h 52m
American Airlines
Deal found 6/13![American Airlines logo]()
$351
One-way flights from Panama City to ChicagoSearch for one-way flight options from Panama City to Chicago. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from Panama City to Chicago. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:25 am
ECP
- ORD
Nonstop2h 44m
United Airlines
Deal found 6/18![United Airlines logo]()
$168
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:05 pm
ECP
- ORD
Nonstop2h 45m
United Airlines
Deal found 6/17![United Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:55 am
ECP
- MDW
Nonstop2h 15m
Southwest
Deal found 6/18![Southwest logo]()
$174
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:47 pm
ECP
- ORD
1 stop5h 46m
Delta
Deal found 6/18![Delta logo]()
$178
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:20 pm
ECP
- MDW
1 stop7h 35m
Southwest
Deal found 6/18![Southwest logo]()
$178
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:30 am
ECP
- MDW
1 stop3h 40m
Southwest
Deal found 6/17![Southwest logo]()
$179
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:40 am
ECP
- MDW
2 stops7h 30m
Southwest
Deal found 6/16![Southwest logo]()
$183
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:08 pm
ECP
- ORD
1 stop6h 51m
Delta
Deal found 6/16![Delta logo]()
$184
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:02 pm
ECP
- MDW
1 stop5h 34m
Delta
Deal found 6/16![Delta logo]()
$184
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:40 am
ECP
- MDW
2 stops7h 30m
Southwest
Deal found 6/18![Southwest logo]()
$189
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:51 pm
ECP
- ORD
1 stop5h 06m
Delta
Deal found 6/18![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:30 pm
ECP
- MDW
1 stop6h 40m
Southwest
Deal found 6/16![Southwest logo]()
$194
Find flight deals from Panama City to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $335 (American Airlines) |
One-way from | $168 (United Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $455 |
Good round-trip deal | $295 or less |
Good one-way deal | $195 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Panama City to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Wed 7/15
7:40 am-4:20 pm
2 stops8h 40m
Chicago Midway
Wed 7/22
1:55 pm-10:10 pm
1 stop8h 15m
$360
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Wed 7/29
4:20 pm-12:10 am
2 stops7h 50m
Chicago Midway
Sat 8/1
7:55 am-2:25 pm
1 stop6h 30m
$366
Panama CityChicago
ECP - ORD
ECPORD
Panama City NW Florida Beaches
Mon 8/10
2:05 pm-4:50 pm
Nonstop2h 45m
Chicago O'Hare Intl
Thu 8/13
10:33 am-1:06 pm
Nonstop2h 33m
$367
Panama CityChicago
ECP - ORD
ECPORD
Panama City NW Florida Beaches
Sat 9/12
11:19 am-4:30 pm
1 stop5h 11m
Chicago O'Hare Intl
Mon 9/14
6:25 pm-11:15 pm
1 stop4h 50m
$377
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Sat 9/12
9:23 am-3:25 pm
1 stop6h 02m
Chicago Midway
Mon 9/14
5:10 pm-11:15 pm
1 stop6h 05m
$377
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Tue 7/28
5:30 pm-10:40 pm
1 stop5h 10m
Chicago Midway
Thu 7/30
8:40 am-10:50 am
Nonstop2h 10m
$378
Quickest round-trip
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Thu 8/13
10:00 am-12:15 pm
Nonstop2h 15m
Chicago Midway
Sun 8/16
2:15 pm-4:20 pm
Nonstop2h 05m
$384
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Thu 8/20
7:35 am-11:51 am
1 stop4h 16m
Chicago Midway
Mon 8/24
12:46 pm-5:56 pm
1 stop5h 10m
$387
Panama CityChicago
ECP - ORD
ECPORD
Panama City NW Florida Beaches
Tue 9/1
1:47 pm-4:29 pm
Nonstop2h 42m
Chicago O'Hare Intl
Fri 9/11
10:40 am-1:13 pm
Nonstop2h 33m
$398
Panama CityChicago
ECP - MDW
ECPMDW
Panama City NW Florida Beaches
Sun 8/2
4:20 pm-6:35 pm
Nonstop2h 15m
Chicago Midway
Sat 8/8
7:45 am-9:55 am
Nonstop2h 10m
$401
Showing 1-10 of 43 resultsSorted by cheapest first
Compare providers for flights from Panama City to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Chicago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama City with our price prediction graph.
ECP-CHI
ECP-ORD
ECP-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Chicago
ECP-CHI
ECP-ORD
ECP-MDW
What is the cheapest month to book a flight from Panama City, Florida to Chicago?
Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $172). Flying from Panama City, Florida to Chicago in July is currently the most expensive (average of $282). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ECP to CHI?
Find hourly flight availability from Panama City to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 45% on flights from Panama City, Florida to Chicago by exploring options for tickets at noon.
Weekly flight availability from Panama City, Florida to Chicago
Explore weekly flight availability from Panama City to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 18, 2026.
The most flights from ECP to CHI are scheduled on a Monday (4 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Panama City, Florida to Chicago?
How far ahead should I book a flight from Panama City, Florida to Chicago?
The price you pay for your flight from Panama City, Florida to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 53 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated June 18, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Panama City to Chicago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Panama City to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Hammond
Porter
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Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 18, 2026.
Complete your trip
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Find flights from Panama City to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Chicago flights
Browse other Panama City and Chicago flight options. Last updated on June 18, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on June 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama City to Chicago flights
Consider these flights traveling from Panama City to Chicago.
Top 4 airlines flying from Panama City to Chicago
Discover the top 4 airlines that operate flights from Panama City to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$207 | Average$371 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$226 | Average$289 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$227 | Average$393 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$401 | FlexibilityNo cancel fee | On-time63% |