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$99+ Cheap flights from Myrtle Beach (MYR) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHI
Jun 28 — Jul 51
Sun 6/28
Sun 7/5
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Chicago

Cheapest flights from Myrtle Beach to Chicago
Explore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 29, 2026.

This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:15 pm
MYR
-
ORD
Nonstop2h 34m
United Airlines
Wed 7/1511:00 am
ORD
-
MYR
Nonstop2h 19m
United Airlines
Deal found 5/28$197
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:55 am
MYR
-
MDW
Nonstop2h 05m
Southwest
Wed 7/156:45 pm
MDW
-
MYR
Nonstop2h 05m
Southwest
Deal found 5/27$197
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:17 pm
MYR
-
ORD
1 stop5h 15m
Delta
Tue 7/75:30 am
ORD
-
MYR
1 stop4h 17m
Delta
Deal found 5/28$217
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:17 pm
MYR
-
MDW
1 stop7h 00m
Delta
Tue 7/712:41 pm
MDW
-
MYR
1 stop5h 26m
Delta
Deal found 5/28$217
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:55 am
MYR
-
MDW
Nonstop2h 05m
Southwest
Tue 8/42:40 pm
MDW
-
MYR
Nonstop2h 00m
Southwest
Deal found 5/29$237
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:10 am
MYR
-
MDW
Nonstop2h 05m
Southwest
Tue 9/1512:45 pm
MDW
-
MYR
1 stop5h 25m
Southwest
Deal found 5/25$244
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:08 pm
MYR
-
ORD
Nonstop2h 34m
United Airlines
Tue 6/3011:00 am
ORD
-
MYR
Nonstop2h 19m
United Airlines
Deal found 5/26$246
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:23 pm
MYR
-
ORD
Nonstop2h 40m
American Airlines
Tue 7/710:45 am
ORD
-
MYR
1 stop6h 52m
American Airlines
Deal found 5/26$247
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:50 pm
MYR
-
ORD
1 stop4h 24m
Delta
Mon 10/53:42 pm
ORD
-
MYR
1 stop6h 48m
Delta
Deal found 5/27$254
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:56 pm
MYR
-
ORD
Nonstop2h 37m
American Airlines
Tue 8/118:15 am
ORD
-
MYR
Nonstop2h 19m
American Airlines
Deal found 5/24$257
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:04 pm
MYR
-
ORD
Nonstop2h 33m
American Airlines
Mon 8/248:15 am
ORD
-
MYR
Nonstop2h 19m
American Airlines
Deal found 5/27$271
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:15 pm
MYR
-
ORD
Nonstop2h 34m
United Airlines
Tue 7/711:00 am
ORD
-
MYR
Nonstop2h 19m
United Airlines
Deal found 5/25$277

Find flight deals from Myrtle Beach to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$197
(United Airlines)

One-way from

$99
(United Airlines)

Popular in

November

Cheapest in

August

Average price

$331

Good round-trip deal

$306 or less

Good one-way deal

$202 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From Myrtle Beach Intl to Chicago (CHI)
Search Deals
One-way flight from Myrtle Beach Intl to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a round-trip flight from Myrtle Beach Intl to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 7/8

10:34 am-5:02 pm

1 stop7h 28m

Chicago O'Hare Intl

Wed 7/15

11:00 am-2:19 pm

Nonstop2h 19m

$207

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 7/8

7:55 am-9:00 am

Nonstop2h 05m

Chicago Midway

Wed 7/15

11:25 am-8:35 pm

2 stops8h 10m

$212

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Thu 9/10

6:40 am-12:20 pm

2 stops6h 40m

Chicago Midway

Tue 9/15

10:10 am-7:10 pm

2 stops8h 00m

$264

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 8/29

6:00 am-9:40 am

1 stop4h 40m

Chicago O'Hare Intl

Sat 9/5

5:28 am-10:47 am

1 stop4h 19m

$291
Quickest round-trip

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 7/15

7:55 am-9:00 am

Nonstop2h 05m

Chicago Midway

Sun 7/19

7:45 pm-10:50 pm

Nonstop2h 05m

$306

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 7/14

3:15 pm-4:49 pm

Nonstop2h 34m

Chicago O'Hare Intl

Fri 7/17

11:00 am-2:19 pm

Nonstop2h 19m

$307

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 6/16

11:32 am-4:26 pm

1 stop5h 54m

Chicago O'Hare Intl

Wed 6/24

8:08 am-3:29 pm

1 stop6h 21m

$321

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 10/22

11:25 am-1:10 pm

Nonstop2h 45m

Chicago O'Hare Intl

Sat 10/24

7:04 am-10:37 am

Nonstop2h 33m

$351

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Thu 10/22

10:55 am-4:25 pm

1 stop6h 30m

Chicago Midway

Sat 10/24

5:25 pm-11:35 pm

1 stop5h 10m

$353

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 8/18

10:23 am-2:30 pm

1 stop5h 07m

Chicago O'Hare Intl

Wed 8/19

11:27 am-2:53 pm

Nonstop2h 26m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/25

Showing 1-10 of 33 resultsSorted by cheapest first
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Compare providers for flights from Myrtle Beach to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Chicago in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Chicago

What is the cheapest month to book a flight from Myrtle Beach to Chicago?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $47). Flying from Myrtle Beach to Chicago in February is currently the most expensive (average of $340). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to CHI?

Find hourly flight availability from Myrtle Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 29, 2026.

A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Chicago at noon. If you’re flexible enough to do this you can expect to save up to 25% on your trip compared to booking a flight in the evening.

Weekly flight availability from Myrtle Beach to Chicago

Explore weekly flight availability from Myrtle Beach to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 29, 2026.

The most flights from MYR to CHI are scheduled on a Thursday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Myrtle Beach to Chicago?

The best insider tips for Myrtle Beach to Chicago flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Myrtle Beach to Chicago trip
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MDW

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on MYR

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated May 29, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Myrtle Beach to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,264 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,264 reviews
Southwest
8.0
Very good
4,264 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,761 reviews
Southwest
8.0
Very good
4,264 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,645 reviews
Southwest
8.0
Very good
4,264 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Spirit Airlines
6.2
Okay
Southwest
8.0
Very good
4,264 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Chicago?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Chicago. 4 airlines have flights from Myrtle Beach Intl to Chicago on a regular basis. Booking flights from Myrtle Beach Intl to Chicago should not be difficult; the airport handles an average of 3 outbound flights to Chicago per day.

  • How long is the flight from Myrtle Beach to Chicago?

    For as low as $212, United Airlines can have you in Chicago from Myrtle Beach in 2h 05m. There are 738 mi between Myrtle Beach and Chicago. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Myrtle Beach to Chicago round-trip?

    Flying on Spirit Airlines is currently your cheapest option to Chicago, with prices starting at $65. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $193 and $232, respectively. You may be able to fly from Myrtle Beach to Chicago for 80% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Myrtle Beach to Chicago one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $60. Users have also found prices from $108 and $127 on American Airlines and United Airlines, respectively.

  • What are the most reliable airlines from Myrtle Beach to Chicago?

    Consider Republic Airways (95%), American Airlines (89%) or SkyWest Airlines (86%) when booking your flight. These represent the most reliable airlines when flying from Myrtle Beach to Chicago.

  • What are the cheapest flights from Myrtle Beach to Chicago?

    Looking at all options, your cheapest flight can be booked for $108. While the most popular route (Myrtle Beach Intl - Chicago O'Hare Intl) can be booked for $197 on average, our data indicates $655 when flying from Myrtle Beach to Chicago.

  • Can I find deals for flights from Myrtle Beach to Chicago that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Chicago.

  • Can I find deals for business class flights from Myrtle Beach to Chicago?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $47). Flying from Myrtle Beach to Chicago in February is currently the most expensive (average of $340). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Benton Harbor
Lansing
Merrillville
Hammond
Porter

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Top 4 airlines flying from Myrtle Beach to Chicago

Discover the top 4 airlines that operate flights from Myrtle Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$65Average$193FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$193Average$366FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$232Average$418FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$244Average$415FlexibilityNo cancel feeOn-time63%

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