$99+ Cheap flights from Myrtle Beach (MYR) to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHI
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Chicago
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Cheapest flights from Myrtle Beach to ChicagoExplore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am -
Nonstop2h 05m
Tue 9/292:40 pm -
Nonstop2h 00m
Deal found 8/25![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm -
1 stop6h 01m
Mon 9/285:30 am -
1 stop7h 03m
Deal found 8/25![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm -
1 stop4h 46m
Mon 9/286:05 am -
1 stop6h 28m
Deal found 8/23![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
Nonstop2h 10m
Mon 11/25:15 am -
2 stops13h 45m
Deal found 8/22![Southwest logo]()
$218
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop9h 05m
Mon 9/217:30 am -
1 stop5h 20m
Deal found 8/25![Southwest logo]()
$222
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm -
2 stops7h 45m
Sat 10/316:25 am -
2 stops7h 50m
Deal found 8/26![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:30 pm -
1 stop8h 55m
Sat 9/266:35 am -
2 stops11h 30m
Deal found 8/21![Southwest logo]()
$228
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
Nonstop2h 36m
Sat 10/175:00 am -
1 stop5h 38m
Deal found 8/26![United Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am -
1 stop29h 30m
Wed 9/237:11 am -
2 stops28h 03m
Deal found 8/21![Multiple Airlines logo]()
$240
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
1 stop5h 39m
Mon 9/285:30 am -
1 stop7h 03m
Deal found 8/26![Delta logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am -
1 stop29h 30m
Thu 9/177:11 am -
1 stop9h 04m
Deal found 8/25![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:05 pm -
1 stop20h 32m
Mon 11/28:00 am -
1 stop24h 50m
Deal found 8/22![Multiple Airlines logo]()
$253
Best flights from Myrtle Beach to ChicagoDiscover carefully curated flight deals from Myrtle Beach to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Myrtle Beach to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:15 am -
1 stop4h 45m
Wed 10/283:05 pm -
Nonstop1h 55m
Deal found 8/25![Southwest logo]()
$207
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:59 pm -
1 stop5h 53m
Tue 12/155:30 am -
1 stop7h 03m
Deal found 8/25![Delta logo]()
$263
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 pm -
Nonstop2h 36m
Mon 10/511:55 am -
Nonstop2h 21m
Deal found 8/24![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
Nonstop2h 10m
Mon 11/25:15 am -
2 stops13h 45m
Deal found 8/22![Southwest logo]()
$218
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm -
2 stops7h 45m
Sat 10/316:25 am -
2 stops7h 50m
Deal found 8/26![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:40 am -
Nonstop2h 10m
Tue 11/38:00 am -
1 stop4h 15m
Deal found 8/25![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:56 pm -
1 stop6h 03m
Sun 10/45:30 am -
1 stop7h 03m
Deal found 8/22![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:24 pm -
Nonstop2h 36m
Mon 9/2110:46 am -
Nonstop2h 31m
Deal found 8/23![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:23 am -
1 stop7h 42m
Sun 10/411:55 am -
Nonstop2h 15m
Deal found 8/21![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:55 pm -
1 stop6h 25m
Mon 9/212:35 pm -
Nonstop2h 00m
Deal found 8/23![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 pm -
Nonstop2h 36m
Wed 10/75:00 am -
1 stop5h 38m
Deal found 8/21![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:25 pm -
2 stops8h 15m
Fri 11/2712:50 pm -
2 stops8h 10m
Deal found 8/22![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:51 pm -
1 stop6h 03m
Mon 11/306:49 am -
1 stop5h 44m
Deal found 8/22![Delta logo]()
$421
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:24 pm -
Nonstop2h 36m
Sat 9/1210:25 am -
1 stop6h 53m
Deal found 8/24![United Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:30 pm -
1 stop8h 55m
Fri 10/24:20 pm -
Nonstop1h 55m
Deal found 8/24![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:00 pm -
Nonstop2h 36m
Fri 10/211:55 am -
Nonstop2h 21m
Deal found 8/24![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:30 pm -
1 stop6h 40m
Mon 9/212:35 pm -
Nonstop2h 00m
Deal found 8/22![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:24 pm -
Nonstop2h 36m
Sun 9/2010:59 am -
Nonstop2h 31m
Deal found 8/25![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:59 pm -
1 stop6h 29m
Mon 9/2110:46 am -
Nonstop2h 31m
Deal found 8/22![United Airlines logo]()
$458
Last-minute flights from Myrtle Beach to ChicagoDiscover last-minute flight deals from Myrtle Beach to Chicago. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Chicago. Data last updated August 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am -
1 stop29h 30m
Wed 9/237:11 am -
2 stops28h 03m
Deal found 8/21![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am -
1 stop29h 30m
Thu 9/177:11 am -
1 stop9h 04m
Deal found 8/25![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:15 am -
1 stop7h 05m
Wed 9/237:11 am -
2 stops28h 03m
Deal found 8/23![Multiple Airlines logo]()
$256
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop9h 05m
Mon 9/217:30 am -
1 stop5h 20m
Deal found 8/25![Southwest logo]()
$222
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:20 pm -
1 stop6h 40m
Fri 9/182:35 pm -
Nonstop2h 00m
Deal found 8/25![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am -
Nonstop2h 05m
Tue 9/292:40 pm -
Nonstop2h 00m
Deal found 8/25![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:50 am -
Nonstop2h 05m
Wed 9/3012:45 pm -
1 stop5h 30m
Deal found 8/26![Southwest logo]()
$207
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm -
1 stop6h 01m
Mon 9/285:30 am -
1 stop7h 03m
Deal found 8/25![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm -
1 stop4h 46m
Mon 9/286:05 am -
1 stop6h 28m
Deal found 8/23![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:15 am -
2 stops5h 50m
Mon 9/281:05 pm -
2 stops5h 40m
Deal found 8/22![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:30 pm -
1 stop8h 55m
Sat 9/266:35 am -
2 stops11h 30m
Deal found 8/21![Southwest logo]()
$228
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
1 stop5h 39m
Mon 9/285:30 am -
1 stop7h 03m
Deal found 8/26![Delta logo]()
$248
One-way flights from Myrtle Beach to ChicagoSearch for one-way flight options from Myrtle Beach to Chicago. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Myrtle Beach to Chicago. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:00 pm -
Nonstop2h 36m
Deal found 8/26![United Airlines logo]()
$99
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:50 am -
Nonstop2h 05m
Deal found 8/26![Southwest logo]()
$99
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:58 pm -
1 stop6h 01m
Deal found 8/25![Delta logo]()
$109
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm -
1 stop4h 46m
Deal found 8/25![Delta logo]()
$109
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop9h 05m
Deal found 8/25![Southwest logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:58 pm -
2 stops21h 47m
Deal found 8/25![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:48 pm -
1 stop26h 32m
Deal found 8/26![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:58 pm -
2 stops22h 39m
Deal found 8/22![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:36 am -
1 stop14h 07m
Deal found 8/24![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:48 pm -
1 stop26h 32m
Deal found 8/22![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:58 pm -
2 stops21h 47m
Deal found 8/22![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:12 pm -
2 stops22h 08m
Deal found 8/23![Multiple Airlines logo]()
$133
Find flight deals from Myrtle Beach to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (Southwest) |
One-way from | $99 (United Airlines) |
Popular in | July |
Cheapest in | January |
Average price | $358 |
Good round-trip deal | $355 or less |
Good one-way deal | $184 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Mon 10/26
6:15 am-10:00 am
1 stop4h 45m
Chicago Midway
Wed 10/28
3:05 pm-6:00 pm
Nonstop1h 55m
$207
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Thu 10/29
6:40 am-7:50 am
Nonstop2h 10m
Chicago Midway
Mon 11/2
5:15 am-8:00 pm
2 stops13h 45m
$218
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Wed 10/28
5:00 pm-11:45 pm
2 stops7h 45m
Chicago Midway
Sat 10/31
6:25 am-3:15 pm
2 stops7h 50m
$227
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Fri 10/30
6:40 am-7:50 am
Nonstop2h 10m
Chicago Midway
Tue 11/3
8:00 am-1:15 pm
1 stop4h 15m
$253
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Fri 12/4
6:59 pm-11:52 pm
1 stop5h 53m
Chicago O'Hare Intl
Tue 12/15
5:30 am-1:33 pm
1 stop7h 03m
$263
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Fri 9/18
1:55 pm-7:20 pm
1 stop6h 25m
Chicago Midway
Mon 9/21
2:35 pm-5:35 pm
Nonstop2h 00m
$299
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Tue 11/17
3:25 pm-10:40 pm
2 stops8h 15m
Chicago Midway
Fri 11/27
12:50 pm-10:00 pm
2 stops8h 10m
$308
Quickest round-trip
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Fri 10/2
5:00 pm-6:36 pm
Nonstop2h 36m
Chicago O'Hare Intl
Mon 10/5
11:55 am-3:16 pm
Nonstop2h 21m
$309
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Thu 10/1
6:56 pm-11:59 pm
1 stop6h 03m
Chicago O'Hare Intl
Sun 10/4
5:30 am-1:33 pm
1 stop7h 03m
$321
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Mon 9/28
2:30 pm-10:25 pm
1 stop8h 55m
Chicago Midway
Fri 10/2
4:20 pm-7:15 pm
Nonstop1h 55m
$328
Showing 1-10 of 36 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Chicago in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Myrtle Beach with our price prediction graph.
MYR-CHI
MYR-ORD
MYR-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Chicago
MYR-CHI
MYR-ORD
MYR-MDW
What is the cheapest month to book a flight from Myrtle Beach to Chicago?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $261). Flying from Myrtle Beach to Chicago in July is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to CHI?
Find hourly flight availability from Myrtle Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 26, 2026.
A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Chicago in the afternoon. If you’re flexible enough to do this you can expect to save up to 47% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Myrtle Beach to Chicago?
Airfare is below average for this route at the moment.
Myrtle Beach to Chicago flights typically cost between $258 and $459 in September.The cheapest round-trip price found within the last 5 days was $197 on Southwest (Sep 22-Sep 29).
The best insider tips for Myrtle Beach to Chicago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Myrtle Beach to Chicago trip
Our travel experts
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated August 26, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Myrtle Beach to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Valparaiso
Hammond
Saint Joseph
Porter
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Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
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Myrtle Beach and Chicago flights
Browse other Myrtle Beach and Chicago flight options. Last updated on August 26, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Myrtle Beach to Chicago
Discover the top 3 airlines that operate flights from Myrtle Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$417 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$271 | Average$418 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$299 | Average$435 | FlexibilityNo cancel fee | On-time71% |