It’s generally more expensive to depart on a Friday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
Due to multiple factors, expect to potentially pay more when booking in July. For low rates, December can be a great choice for travel to Charlottesville. Flights to Charlottesville from Greenville in December are about $458 on average during December, but can be found for as low as $213.
A simple way to save on the total cost of your ticket is to fly from Greenville to Charlottesville in the afternoon. If you’re flexible enough to do this you can expect to save up to 8% on your trip compared to booking a flight at noon.