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$104+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in February or October, booked 56 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday

Cheap flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$218
(Kiwi.com)

One-way from

$104
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$399

Good round-trip deal

$309 or less

Good one-way deal

$179 or less
From Des Moines to Charlotte Douglas
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One-way flight from Des Moines to Charlotte Douglas
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
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Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
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Find flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/298:25 amDSM - CLT
1 stop29h 43mMultiple Airlines
Wed 10/110:46 amCLT - DSM
1 stop24h 05mMultiple Airlines
Deal found 9/9$219
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:07 amDSM - CLT
1 stop9h 55mAmerican Airlines
Sat 10/188:45 pmCLT - DSM
Nonstop2h 43mAmerican Airlines
Deal found 9/9$225
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:45 pmDSM - CLT
1 stop3h 45mSouthwest
Wed 11/56:10 amCLT - DSM
2 stops6h 15mSouthwest
Deal found 9/9$227
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:25 amDSM - CLT
2 stops11h 15mSouthwest
Wed 11/56:10 amCLT - DSM
2 stops6h 15mSouthwest
Deal found 9/11$236
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:25 amDSM - CLT
1 stop12h 20mSouthwest
Wed 10/292:00 pmCLT - DSM
1 stop8h 50mSouthwest
Deal found 9/11$237
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/189:19 amDSM - CLT
1 stop21h 41mMultiple Airlines
Fri 10/318:52 amCLT - DSM
1 stop6h 58mMultiple Airlines
Deal found 9/9$240
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/49:19 amDSM - CLT
1 stop21h 28mMultiple Airlines
Fri 10/1010:06 pmCLT - DSM
1 stop11h 23mMultiple Airlines
Deal found 9/9$241
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/510:41 amDSM - CLT
1 stop22h 35mMultiple Airlines
Tue 10/72:40 pmCLT - DSM
2 stops24h 12mMultiple Airlines
Deal found 9/9$252
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:30 amDSM - CLT
1 stop7h 16mMultiple Airlines
Fri 10/318:52 amCLT - DSM
1 stop6h 58mMultiple Airlines
Deal found 9/8$255

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Des Moines

Fly to

Charlotte

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 10/22

4:45 pm-9:30 pm

1 stop3h 45m

Charlotte Douglas

Wed 11/5

12:55 pm-9:35 pm

1 stop9h 40m

$227

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 10/25

7:25 am-8:45 pm

1 stop12h 20m

Charlotte Douglas

Wed 10/29

2:00 pm-9:50 pm

1 stop8h 50m

$237

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 10/18

9:19 am-8:00 am

1 stop21h 41m

Charlotte Douglas

Fri 10/31

8:52 am-2:50 pm

1 stop6h 58m

$240

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 10/3

2:25 pm-12:53 pm

2 stops21h 28m

Charlotte Douglas

Wed 10/8

5:45 am-10:01 am

1 stop29h 16m

$281

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 10/8

3:17 pm-7:47 am

1 stop15h 30m

Charlotte Douglas

Wed 10/15

6:00 am-1:52 pm

2 stops32h 52m

$288

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 10/9

2:37 pm-4:39 pm

1 stop25h 02m

Charlotte Douglas

Sun 10/12

5:34 pm-1:52 pm

1 stop21h 18m

$289

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 2/8

6:10 am-4:20 pm

2 stops9h 10m

Charlotte Douglas

Wed 2/11

1:35 pm-7:20 pm

1 stop6h 45m

$294

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 10/11

6:22 pm-9:41 pm

Nonstop2h 19m

Charlotte Douglas

Sat 10/18

1:25 pm-2:58 pm

Nonstop2h 33m

$301

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 11/1

7:25 am-8:45 pm

1 stop12h 20m

Charlotte Douglas

Sun 11/9

6:25 pm-11:35 pm

1 stop6h 10m

$311

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 10/14

4:45 pm-9:30 pm

1 stop3h 45m

$111

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 19 results
1
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Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on August 29, 2025.

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $248). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Des Moines to Charlotte in the afternoon. Doing so could potentially save you 24% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Des Moines to Charlotte?

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 19m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Des Moines to Douglas offered by 2 different airlines.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 3h 45m. Fly via Southwest to get the fastest option. There are 813 mi between Des Moines and Charlotte.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Delta is currently your cheapest option to Charlotte, with prices starting at $131. Another option worth looking into is American Airlines, starting at $257 round trip. Delta is priced at 68% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $135. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $236 on average, our data indicates $380 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $248). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Hickory
Huntersville
Mooresville
Morganton
Cornelius
Lancaster
Boone
Rock Hill
Salisbury
Shelby
Kannapolis
Fort Mill
Pineville

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Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$334FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$257Average$410FlexibilityNo cancel feeOn-time71%

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