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$111+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
nov. 26 — déc. 31
mer. 11/26
mer. 12/3
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in February or April, booked 56 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday

Cheap flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octobre 27, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$218
(Mytrip)

One-way from

$111
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$421

Good round-trip deal

$352 or less

Good one-way deal

$203 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
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From Des Moines to Charlotte Douglas
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One-way flight from Des Moines to Charlotte Douglas
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
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Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
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Find flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octobre 27, 2025.

This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/62:41 pmDSM - CLT
1 stop25h 36mFrontier
jeu. 11/136:07 pmCLT - DSM
1 stop20h 42mFrontier
Deal found 10/24$218
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/146:40 pmDSM - CLT
1 stop12h 22mAmerican Airlines
sam. 11/1511:50 amCLT - DSM
Nonstop2h 41mAmerican Airlines
Deal found 10/25$239
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/108:40 amDSM - CLT
1 stop13h 28mMultiple Airlines
ven. 11/145:45 amCLT - DSM
1 stop10h 10mMultiple Airlines
Deal found 10/26$254
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/2311:14 amDSM - CLT
1 stop8h 15mFrontier
lun. 1/512:17 pmCLT - DSM
1 stop8h 27mFrontier
Deal found 10/27$266
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/86:35 amDSM - CLT
1 stop28h 29mMultiple Airlines
lun. 12/159:20 pmCLT - DSM
2 stops38h 21mMultiple Airlines
Deal found 10/26$268
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/76:40 pmDSM - CLT
1 stop12h 22mAmerican Airlines
sam. 11/811:50 amCLT - DSM
Nonstop2h 41mAmerican Airlines
Deal found 10/25$269
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/99:03 pmDSM - CLT
2 stops34h 59mMultiple Airlines
mer. 11/1210:07 amCLT - DSM
1 stop24h 53mMultiple Airlines
Deal found 10/26$272
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/142:34 pmDSM - CLT
2 stops23h 22mFrontier
dim. 11/166:02 pmCLT - DSM
1 stop20h 45mFrontier
Deal found 10/25$279
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/1610:50 amDSM - CLT
1 stop21h 12mMultiple Airlines
dim. 11/2310:17 amCLT - DSM
1 stop29h 41mMultiple Airlines
Deal found 10/24$280
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/232:35 pmDSM - CLT
1 stop24h 44mMultiple Airlines
lun. 12/299:43 pmCLT - DSM
2 stops26h 27mMultiple Airlines
Deal found 10/27$284
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/67:30 amDSM - CLT
2 stops13h 26mMultiple Airlines
jeu. 11/131:20 pmCLT - DSM
1 stop26h 35mMultiple Airlines
Deal found 10/24$301

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 27, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Des Moines

Fly to

Charlotte

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

ven. 11/14

6:40 pm-8:02 am

1 stop12h 22m

Charlotte Douglas

sam. 11/15

11:50 am-1:31 pm

Nonstop2h 41m

$239

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

ven. 11/14

2:34 pm-2:56 pm

2 stops23h 22m

Charlotte Douglas

dim. 11/16

6:02 pm-1:47 pm

1 stop20h 45m

$279

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

lun. 11/10

2:32 pm-4:48 pm

2 stops25h 16m

Charlotte Douglas

ven. 11/14

5:45 am-2:55 pm

1 stop10h 10m

$282

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

ven. 11/21

6:40 am-11:13 pm

1 stop15h 33m

Charlotte Douglas

dim. 11/23

3:51 pm-9:09 pm

3 stops30h 18m

$386

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

mar. 12/9

6:33 pm-11:42 pm

1 stop4h 09m

Charlotte Douglas

mar. 12/16

5:00 pm-9:15 pm

1 stop5h 15m

$393

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

mar. 11/25

2:15 pm-5:34 pm

Nonstop2h 19m

Charlotte Douglas

lun. 12/1

1:54 pm-3:33 pm

Nonstop2h 39m

$397

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

ven. 12/12

8:00 am-6:05 pm

1 stop9h 05m

Charlotte Douglas

lun. 12/15

8:30 am-7:55 pm

2 stops12h 25m

$401

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

ven. 1/23

11:09 am-4:27 pm

1 stop4h 18m

$122

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

lun. 11/24

6:40 am-2:56 pm

1 stop7h 16m

$124

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

dim. 1/25

2:58 pm-9:27 am

1 stop17h 29m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Charlotte

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on October 24, 2025.

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $145). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octobre 27, 2025.

It’s typically best to fly out from Des Moines to Charlotte in the evening. Doing so could potentially save you 62% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated octobre 27, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 18m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Des Moines to Douglas offered by 2 different airlines.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 12h 22m. Fly via American Airlines or Frontier to get the fastest option. There are 813 mi between Des Moines and Charlotte. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Delta is currently your cheapest option to Charlotte, with prices starting at $216. Another option worth looking into is American Airlines, starting at $303 round trip. Delta is priced at 47% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $130. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $268 on average, our data indicates $516 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $145). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Hickory
Boone
Salisbury
Mooresville
Morganton
Huntersville
Lancaster
Rock Hill
Shelby
Kannapolis
Fort Mill
Pineville

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Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$303Average$424FlexibilityNo cancel feeOn-time71%

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