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$118+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in September or October, booked 56 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$220
(Mytrip)

One-way from

$118
(Southwest)

Popular in

March

Cheapest in

September

Average price

$409

Good round-trip deal

$305 or less

Good one-way deal

$168 or less
From Des Moines to Charlotte Douglas
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One-way flight from Des Moines to Charlotte Douglas
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
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Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
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Find flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/224:29 pmDSM - CLT
2 stops14h 36mMultiple Airlines
Mon 8/252:52 pmCLT - DSM
1 stop6h 49mMultiple Airlines
Deal found 7/28$220
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:35 amDSM - CLT
1 stop7h 00mSouthwest
Sat 9/610:35 amCLT - DSM
1 stop5h 25mSouthwest
Deal found 7/29$242
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:25 pmDSM - CLT
1 stop25h 18mFrontier
Thu 10/25:20 pmCLT - DSM
1 stop21h 20mFrontier
Deal found 7/27$245
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/164:23 pmDSM - CLT
Nonstop2h 22mAmerican Airlines
Sat 8/1610:32 pmCLT - DSM
1 stop11h 05mAmerican Airlines
Deal found 7/27$289
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:44 amDSM - CLT
1 stop6h 18mDelta
Wed 9/176:59 amCLT - DSM
1 stop4h 41mDelta
Deal found 7/26$393

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Des Moines

Fly to

Charlotte

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 8/22

4:29 pm-8:05 am

2 stops14h 36m

Charlotte Douglas

Mon 8/25

2:52 pm-8:41 pm

1 stop6h 49m

$220

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 9/25

2:25 pm-4:43 pm

1 stop25h 18m

Charlotte Douglas

Thu 10/2

5:20 pm-1:40 pm

1 stop21h 20m

$245

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 8/16

4:23 pm-7:45 pm

Nonstop2h 22m

Charlotte Douglas

Sat 8/16

10:32 pm-8:37 am

1 stop11h 05m

$289

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/6

6:10 am-4:35 pm

2 stops9h 25m

Charlotte Douglas

Sat 9/13

10:35 am-3:00 pm

1 stop5h 25m

$320

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/13

5:44 am-1:02 pm

1 stop6h 18m

Charlotte Douglas

Wed 9/17

6:59 am-10:40 am

1 stop4h 41m

$393

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 10/28

4:45 pm-9:30 pm

1 stop3h 45m

$118

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 8/28

3:23 pm-4:37 pm

1 stop24h 14m

$127

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 8/15

1:36 pm-8:05 am

2 stops17h 29m

$147

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 10/31

5:14 pm-11:50 pm

1 stop5h 36m

$197

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 9/29

5:13 pm-11:14 pm

1 stop29h 01m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on July 25, 2025.

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $248). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s typically best to fly out from Des Moines to Charlotte in the afternoon. Doing so could potentially save you 25% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated July 29, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,238 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Frontier is currently your cheapest option to Charlotte, with prices starting at $245. Additional round-trip tickets that might be worth considering are offered by American Airlines and Southwest, with the lowest prices starting at $289 and $320, respectively. Frontier is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Charlotte one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $118. Users have also found prices from $127 and $197 on Frontier and Delta, respectively.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $79. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $220 on average our data indicates $2,006 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $248). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Rock Hill
Matthews
Gastonia
Huntersville
Boone
Salisbury
Statesville
Mooresville
Cornelius
Lancaster
Kannapolis
Shelby
Fort Mill
Pineville
Hickory

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Alternative routes for Des Moines to Charlotte

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Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$338FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$401FlexibilityNo cancel feeOn-time71%

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