HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Charlotte

$92+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Apr 11 — Apr 181
Sat 4/11
Sat 4/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Charlotte with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in September or April, booked 46 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This CheapOair deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
DSM
-
CLT
1 stop25h 52m
Frontier
Tue 5/55:20 pm
CLT
-
DSM
1 stop21h 11m
Frontier
Deal found 3/11$191
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
-
CLT
1 stop25h 32m
Frontier
Sun 5/107:49 pm
CLT
-
DSM
1 stop18h 40m
Frontier
Deal found 3/9$226
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
-
CLT
1 stop21h 13m
Multiple Airlines
Thu 6/43:49 pm
CLT
-
DSM
1 stop6h 38m
Multiple Airlines
Deal found 3/10$255
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:26 am
DSM
-
CLT
1 stop21h 34m
Multiple Airlines
Tue 3/249:00 pm
CLT
-
DSM
2 stops48h 43m
Multiple Airlines
Deal found 3/9$256
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
-
CLT
1 stop21h 13m
Multiple Airlines
Wed 6/39:54 pm
CLT
-
DSM
2 stops24h 33m
Multiple Airlines
Deal found 3/10$269
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:20 am
DSM
-
CLT
1 stop20h 43m
Multiple Airlines
Wed 3/258:56 am
CLT
-
DSM
2 stops36h 47m
Multiple Airlines
Deal found 3/9$277
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:23 pm
DSM
-
CLT
1 stop23h 54m
Multiple Airlines
Tue 3/319:00 pm
CLT
-
DSM
2 stops41h 46m
Multiple Airlines
Deal found 3/8$279
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:45 am
DSM
-
CLT
1 stop12h 04m
Multiple Airlines
Sun 5/107:49 pm
CLT
-
DSM
1 stop18h 40m
Multiple Airlines
Deal found 3/7$285
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
DSM
-
CLT
1 stop25h 15m
Frontier
Sun 3/227:43 pm
CLT
-
DSM
1 stop24h 33m
Frontier
Deal found 3/10$288
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
-
CLT
1 stop21h 13m
Multiple Airlines
Fri 6/512:50 pm
CLT
-
DSM
1 stop11h 37m
Multiple Airlines
Deal found 3/10$296
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
-
CLT
1 stop23h 40m
Multiple Airlines
Sun 5/38:50 am
CLT
-
DSM
1 stop14h 16m
Multiple Airlines
Deal found 3/12$303

Find flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$191
(CheapOair)

One-way from

$92
(CheapOair)

Popular in

March

Cheapest in

September

Average price

$650

Good round-trip deal

$386 or less

Good one-way deal

$243 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
Search Deals
From Des Moines to Charlotte Douglas
Search Deals
One-way flight from Des Moines to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
Search Deals
Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 6/6

3:35 pm-8:45 pm

1 stop4h 10m

Charlotte Douglas

Wed 6/10

7:05 pm-10:45 pm

1 stop4h 40m

$341

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 4/7

3:15 pm-8:55 pm

1 stop4h 40m

Charlotte Douglas

Tue 4/14

7:35 am-11:25 am

1 stop4h 50m

$351

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 5/11

4:20 pm-10:00 pm

1 stop4h 40m

Charlotte Douglas

Wed 5/13

6:20 pm-10:10 pm

1 stop4h 50m

$369

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 4/9

5:25 am-6:20 pm

2 stops11h 55m

Charlotte Douglas

Thu 4/16

6:15 am-1:10 pm

2 stops7h 55m

$393

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 4/29

3:15 pm-8:55 pm

1 stop4h 40m

Charlotte Douglas

Sun 5/3

7:00 am-11:25 am

1 stop5h 25m

$402

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 3/31

3:40 pm-9:05 pm

1 stop4h 25m

Charlotte Douglas

Sun 4/5

4:35 pm-11:35 pm

1 stop8h 00m

$425

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 3/31

3:40 pm-9:05 pm

1 stop4h 25m

Charlotte Douglas

Sun 5/3

12:50 pm-10:20 pm

2 stops10h 30m

$425

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 4/16

2:44 pm-9:27 pm

1 stop5h 43m

Charlotte Douglas

Sun 4/19

6:46 am-11:05 am

1 stop5h 19m

$451
Cheapest one-way
Quickest one-way

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 4/21

3:15 pm-8:55 pm

1 stop4h 40m

$171

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 5/9

5:35 am-11:35 am

1 stop5h 00m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Charlotte

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on March 6, 2026.

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $237). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 12, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Charlotte as you normally would.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated March 12, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,435 reviews
Delta
7.9
Good
8,286 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 23m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Des Moines to Douglas offered by 2 different airlines.

  • How popular is this Des Moines to Charlotte flight route?

    The Des Moines to Charlotte Douglas flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 4h 10m. Fly via Southwest to get the fastest option. There are 813 mi between Des Moines and Charlotte.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Delta is currently your cheapest option to Charlotte, with prices starting at $228. Another option worth looking into is American Airlines, starting at $316 round trip. Delta is priced at 49% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $168. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $255 on average, our data indicates $380 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $237). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Matthews
Gaffney
Gastonia
Salisbury
Hickory
Morganton
Mooresville
Huntersville
Boone
Rock Hill
Lancaster
Shelby
Kannapolis
Fort Mill
Statesville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$448FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$316Average$434FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights