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$93+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in February or April, booked 56 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:14 amDSM - CLT
1 stop8h 15mFrontier
Fri 1/212:17 pmCLT - DSM
1 stop8h 27mFrontier
Deal found 12/11$392
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:52 pmDSM - CLT
1 stop12h 12mAmerican Airlines
Sat 1/311:42 amCLT - DSM
Nonstop2h 32mAmerican Airlines
Deal found 12/10$393
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:31 amDSM - CLT
2 stops24h 56mMultiple Airlines
Mon 12/299:38 pmCLT - DSM
1 stop26h 32mMultiple Airlines
Deal found 12/11$403
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:07 pmDSM - CLT
Nonstop2h 23mAmerican Airlines
Sat 1/311:42 amCLT - DSM
Nonstop2h 32mAmerican Airlines
Deal found 12/12$421
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:56 pmDSM - CLT
1 stop12h 08mAmerican Airlines
Thu 1/110:41 pmCLT - DSM
1 stop10h 34mAmerican Airlines
Deal found 12/10$432
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:45 pmDSM - CLT
1 stop27h 48mMultiple Airlines
Tue 12/309:24 amCLT - DSM
2 stops14h 46mMultiple Airlines
Deal found 12/11$446
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:31 amDSM - CLT
2 stops24h 56mMultiple Airlines
Tue 12/307:00 amCLT - DSM
1 stop17h 10mMultiple Airlines
Deal found 12/11$447
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:47 pmDSM - CLT
2 stops16h 52mMultiple Airlines
Mon 12/299:38 pmCLT - DSM
1 stop26h 32mMultiple Airlines
Deal found 12/11$452

Find flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$231
(American Airlines)

One-way from

$93
(Trip.com)

Popular in

December

Cheapest in

February

Average price

$525

Good round-trip deal

$352 or less

Good one-way deal

$233 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
Search Deals
From Des Moines to Charlotte Douglas
Search Deals
One-way flight from Des Moines to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
Search Deals
Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Des Moines

Fly to

Charlotte

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/10

5:58 pm-4:42 pm

1 stop21h 44m

Charlotte Douglas

Tue 1/13

7:43 pm-5:24 pm

2 stops22h 41m

$269

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/25

2:58 pm-8:11 am

1 stop16h 13m

Charlotte Douglas

Sun 2/1

1:24 pm-10:46 pm

1 stop10h 22m

$297

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 1/29

4:30 pm-12:40 am

3 stops31h 10m

Charlotte Douglas

Sun 2/1

7:43 pm-10:19 am

2 stops15h 36m

$341

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/17

11:42 am-10:54 pm

1 stop10h 12m

Charlotte Douglas

Tue 1/20

9:33 pm-11:08 pm

Nonstop2h 35m

$345

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 1/7

6:10 am-4:20 pm

2 stops9h 10m

Charlotte Douglas

Wed 1/14

1:35 pm-7:20 pm

1 stop6h 45m

$366

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/10

5:45 am-2:45 pm

1 stop8h 00m

Charlotte Douglas

Tue 1/13

1:35 pm-7:20 pm

1 stop6h 45m

$374

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 2/17

6:25 am-3:35 pm

1 stop8h 10m

Charlotte Douglas

Thu 2/19

5:05 pm-10:15 pm

1 stop6h 10m

$374

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/10

1:16 pm-7:09 pm

1 stop4h 53m

Charlotte Douglas

Tue 1/13

9:33 pm-11:08 pm

Nonstop2h 35m

$383

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 3/10

10:40 am-8:03 am

1 stop20h 23m

$93

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/11

4:30 pm-4:43 pm

2 stops47h 13m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 15 results
1
2

Compare providers for flights from Des Moines to Charlotte

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on December 5, 2025.

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $216). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s typically best to fly out from Des Moines to Charlotte in the evening. Doing so could potentially save you 61% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 18m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Des Moines to Douglas offered by 2 different airlines.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 9h 10m. Fly via American Airlines or Southwest to get the fastest option. There are 813 mi between Des Moines and Charlotte. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Delta is currently your cheapest option to Charlotte, with prices starting at $216. Another option worth looking into is American Airlines, starting at $325 round trip. Delta is priced at 49% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $145. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $245 on average, our data indicates $416 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $216). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Salisbury
Hickory
Boone
Mooresville
Morganton
Huntersville
Lancaster
Rock Hill
Shelby
Kannapolis
Fort Mill

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Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$324Average$422FlexibilityNo cancel feeOn-time71%

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