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Central America

$129+ Cheap flights from Knoxville (TYS) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SJO
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Knoxville to Central America

Cheapest flights from Knoxville to Central America
Explore the most affordable flight options available from Knoxville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/11:39 pm
TYS
-
SAL
1 stop31h 16m
Multiple Airlines
Sat 2/712:51 pm
SAL
-
TYS
2 stops28h 02m
Multiple Airlines
Deal found 1/19$375
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:56 pm
TYS
-
SJO
2 stops46h 34m
Multiple Airlines
Wed 3/412:35 pm
SJO
-
TYS
1 stop27h 21m
Multiple Airlines
Deal found 1/21$383
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:56 pm
TYS
-
SAL
1 stop26h 59m
Multiple Airlines
Sat 2/2810:05 pm
SAL
-
TYS
1 stop23h 02m
Multiple Airlines
Deal found 1/20$394
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/315:59 pm
TYS
-
GUA
1 stop19h 30m
Multiple Airlines
Sat 5/1610:00 am
GUA
-
TYS
2 stops27h 41m
Multiple Airlines
Deal found 1/20$397
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:25 pm
TYS
-
SJO
1 stop20h 57m
Multiple Airlines
Tue 4/2112:31 pm
SJO
-
TYS
1 stop20h 05m
Multiple Airlines
Deal found 1/20$401
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
-
SJO
1 stop20h 09m
Multiple Airlines
Tue 4/2112:31 pm
SJO
-
TYS
1 stop20h 05m
Multiple Airlines
Deal found 1/20$409
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:58 am
TYS
-
SJO
1 stop25h 42m
Multiple Airlines
Wed 2/257:50 pm
SJO
-
TYS
2 stops25h 17m
Multiple Airlines
Deal found 1/21$411
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:53 pm
TYS
-
SJO
2 stops46h 37m
Multiple Airlines
Sat 3/71:31 pm
SJO
-
TYS
1 stop29h 26m
Multiple Airlines
Deal found 1/21$414
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:22 pm
TYS
-
SJO
2 stops42h 00m
Multiple Airlines
Sun 3/112:35 pm
SJO
-
TYS
1 stop28h 56m
Multiple Airlines
Deal found 1/21$415
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:20 pm
TYS
-
SJO
1 stop18h 22m
Multiple Airlines
Tue 4/2112:31 pm
SJO
-
TYS
1 stop20h 05m
Multiple Airlines
Deal found 1/20$417
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
TYS
-
SAL
1 stop7h 37m
American Airlines
Wed 4/291:19 pm
SAL
-
TYS
1 stop8h 40m
American Airlines
Deal found 1/20$419
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:30 am
TYS
-
SAL
2 stops23h 30m
Multiple Airlines
Mon 4/208:45 am
SAL
-
TYS
1 stop11h 39m
Multiple Airlines
Deal found 1/21$422

Find flight deals from Knoxville to Central America

Keep the following information in mind while searching for Knoxville to Central America flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Ovago
2 stars

Round-trip from

$383
(Kiwi.com)

One-way from

$129
(Kiwi.com)

Popular in

April

Cheapest in

May

Average price

$397
Provider with most accurate pricing for Knoxville McGhee Tyson-San Salvador El Salvador Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Salvador El Salvador Intl flights.
Search Deals
From Knoxville McGhee Tyson to Central America
Search Deals
One-way flight from Knoxville McGhee Tyson to Central America
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($4 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Knoxville to Central America that are best for you.

Fly from

Knoxville

Fly to

Central America

Route

Depart

Return

Price

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-3:30 pm

2 stops46h 34m

San José Juan Santamaria Intl

Wed 3/4

12:35 pm-4:56 pm

1 stop27h 21m

$383

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-7:55 pm

1 stop26h 59m

San Salvador El Salvador Intl

Sat 2/28

10:05 pm-10:07 pm

1 stop23h 02m

$394

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Thu 3/12

9:43 pm-11:19 am

1 stop15h 36m

San José Juan Santamaria Intl

Wed 3/25

12:24 pm-12:03 pm

1 stop21h 39m

$414

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Sun 3/1

5:53 pm-3:30 pm

2 stops46h 37m

San José Juan Santamaria Intl

Sat 3/7

1:31 pm-7:57 pm

1 stop29h 26m

$414

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Tue 3/24

6:00 am-11:37 am

1 stop7h 37m

San Salvador El Salvador Intl

Wed 4/29

1:19 pm-11:59 pm

1 stop8h 40m

$419

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Mon 4/13

7:30 am-5:00 am

2 stops23h 30m

San Salvador El Salvador Intl

Mon 4/20

8:45 am-10:24 pm

1 stop11h 39m

$422

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Fri 2/20

2:06 pm-11:40 am

1 stop22h 34m

San José Juan Santamaria Intl

Sun 3/1

12:35 pm-6:31 pm

1 stop28h 56m

$423

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 1/31

5:59 pm-12:29 pm

1 stop19h 30m

Guatemala City La Aurora

Sat 5/16

8:00 pm-3:41 pm

1 stop17h 41m

$426

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Sun 4/12

3:51 pm-11:19 am

1 stop21h 28m

San José Juan Santamaria Intl

Tue 4/21

12:31 pm-10:36 am

1 stop20h 05m

$434

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Thu 4/9

11:27 am-8:30 am

2 stops23h 03m

San José Juan Santamaria Intl

Tue 4/21

12:31 pm-10:36 am

1 stop20h 05m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 45 results
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Best time to book a flight from Knoxville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Central America

What is the cheapest month to book a flight from Knoxville to Central America?

Currently, April is the cheapest month in which you can book a flight from Knoxville to Central America (average of $86). Flying from Knoxville to Central America in September is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated January 21, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Central America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,089 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,089 reviews
Delta
7.9
Good
8,089 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,191 reviews
Delta
7.9
Good
8,089 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,089 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Central America?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Central America. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Central America?

    Departing from Knoxville to Central America will take you 7h 37m. There are 1576 mi between Knoxville and Central America. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Central America?

    While some choose either Knoxville McGhee Tyson - Panama City Tocumen Intl or Knoxville McGhee Tyson - Liberia, Knoxville McGhee Tyson - San José Juan Santamaria Intl is the most popular route from Knoxville to Central America.

  • Can I find deals for flights from Knoxville to Central America that include hotel bookings?

    Yes. In addition to deals on Knoxville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Central America.

  • Can I find deals for business class flights from Knoxville to Central America?

    Yes. Cheapflights offers flight deals from Knoxville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Central America?

    Currently, April is the cheapest month in which you can book a flight from Knoxville to Central America (average of $86). Flying from Knoxville to Central America in September is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Central America

Discover the top 3 airlines that operate flights from Knoxville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$269Average$597FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$312Average$648FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$357Average$636FlexibilityNo cancel feeOn-time71%

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