$41+ Cheap flights from Tampa to St. Louis (TPA - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — STL
Oct 26 — Nov 21
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Tampa to Lambert-St Louis are usually found in November or December, booked 85 days in advance, depart on a Friday or Thursday and return on a Saturday
Cheap flight deals from Tampa to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Tampa to St. LouisExplore the most affordable flight options available from Tampa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
Explore the most affordable flight options available from Tampa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:08 am -
1 stop11h 32m
Mon 10/196:35 pm -
1 stop16h 10m
Deal found 9/22![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:11 pm -
1 stop25h 29m
Mon 11/166:44 pm -
1 stop16h 05m
Deal found 9/22![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:08 am -
1 stop11h 32m
Wed 10/286:44 pm -
1 stop21h 38m
Deal found 9/23![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:08 am -
1 stop11h 32m
Fri 10/236:35 pm -
1 stop22h 49m
Deal found 9/21![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:08 am -
1 stop11h 32m
Wed 10/286:44 pm -
1 stop21h 38m
Deal found 9/21![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:57 pm -
1 stop24h 43m
Mon 11/26:44 pm -
1 stop21h 49m
Deal found 9/25![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:57 pm -
1 stop24h 43m
Mon 10/196:35 pm -
1 stop16h 10m
Deal found 9/23![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:08 am -
1 stop11h 32m
Fri 10/166:35 pm -
1 stop22h 49m
Deal found 9/23![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:54 pm -
1 stop5h 46m
Mon 11/26:44 pm -
1 stop16h 05m
Deal found 9/23![Frontier logo]()
$131
Best flights from Tampa to St. LouisDiscover carefully curated flight deals from Tampa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
Discover carefully curated flight deals from Tampa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:57 pm -
1 stop24h 43m
Mon 11/26:44 pm -
1 stop21h 49m
Deal found 9/25![Frontier logo]()
$106
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
Nonstop2h 25m
Mon 11/25:00 am -
Nonstop2h 20m
Deal found 9/25![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:26 am -
1 stop5h 47m
Wed 10/216:00 am -
2 stops8h 16m
Deal found 9/25![United Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:15 am -
Nonstop2h 25m
Sat 11/72:30 pm -
Nonstop2h 15m
Deal found 9/24![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
Nonstop2h 25m
Mon 10/197:55 pm -
Nonstop2h 20m
Deal found 9/22![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:25 am -
Nonstop2h 25m
Sat 10/244:50 pm -
Nonstop2h 20m
Deal found 9/21![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:15 am -
Nonstop2h 25m
Mon 10/195:25 am -
1 stop5h 45m
Deal found 9/23![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:26 am -
1 stop7h 51m
Sat 10/248:00 am -
2 stops9h 03m
Deal found 9/25![United Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:40 am -
2 stops6h 50m
Wed 10/2111:25 am -
1 stop6h 50m
Deal found 9/25![Southwest logo]()
$282
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:00 am -
1 stop8h 10m
Mon 10/267:30 am -
2 stops9h 32m
Deal found 9/25![United Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am -
2 stops10h 06m
Wed 10/2112:20 pm -
1 stop8h 38m
Deal found 9/23![United Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:20 am -
1 stop5h 35m
Thu 10/2210:25 am -
1 stop5h 45m
Deal found 9/24![Southwest logo]()
$348
Last-minute flights from Tampa to St. LouisDiscover last-minute flight deals from Tampa to St. Louis. Data last updated September 26, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to St. Louis. Data last updated September 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:08 am -
1 stop11h 32m
Mon 10/196:35 pm -
1 stop16h 10m
Deal found 9/22![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:08 am -
1 stop11h 32m
Fri 10/166:35 pm -
1 stop22h 49m
Deal found 9/23![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:57 pm -
1 stop24h 43m
Mon 10/196:35 pm -
1 stop16h 10m
Deal found 9/23![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:08 am -
1 stop11h 32m
Wed 10/286:44 pm -
1 stop21h 38m
Deal found 9/23![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:08 am -
1 stop11h 32m
Fri 10/236:35 pm -
1 stop22h 49m
Deal found 9/21![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:08 am -
1 stop11h 32m
Mon 10/266:35 pm -
1 stop16h 14m
Deal found 9/21![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:08 am -
1 stop11h 32m
Wed 10/286:44 pm -
1 stop21h 38m
Deal found 9/21![Frontier logo]()
$101
This Mytrip deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:41 pm -
1 stop4h 59m
Mon 11/26:44 pm -
2 stops19h 27m
Deal found 9/24![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:57 pm -
1 stop24h 43m
Mon 11/26:44 pm -
1 stop21h 49m
Deal found 9/25![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:54 pm -
1 stop5h 46m
Mon 11/26:44 pm -
1 stop16h 05m
Deal found 9/23![Frontier logo]()
$131
One-way flights from Tampa to St. LouisSearch for one-way flight options from Tampa to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
Search for one-way flight options from Tampa to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:08 am -
1 stop11h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Frontier logo]()
$41
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:52 pm -
1 stop28h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Frontier logo]()
$42
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:57 pm -
1 stop24h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:46 pm -
1 stop11h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:59 pm -
1 stop24h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:11 pm -
1 stop25h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:57 pm -
1 stop24h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Frontier logo]()
$78
Find flight deals from Tampa to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $88 (Kiwi.com) |
One-way from | $41 (Kiwi.com) |
Popular in | June |
Cheapest in | November |
Average price | $417 |
Good round-trip deal | $307 or less |
Good one-way deal | $213 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
Use the filters below to find and compare flights from Tampa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Thu 10/29
5:57 pm-5:40 pm
1 stop24h 43m
Lambert-St Louis
Mon 11/2
6:44 pm-5:33 pm
1 stop21h 49m
$106
Quickest round-trip
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Mon 12/21
6:15 am-7:40 am
Nonstop2h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$129
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Mon 11/9
6:15 am-7:40 am
Nonstop2h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$129
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Tue 10/20
6:10 am-7:35 am
Nonstop2h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$129
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Mon 12/21
7:20 pm-11:55 pm
1 stop5h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Sat 10/24
5:10 am-9:42 am
1 stop5h 32m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Fri 12/4
10:35 am-12:00 pm
Nonstop2h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$165
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Thu 12/24
6:00 pm-7:30 pm
Nonstop2h 30m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$165
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Fri 12/25
8:20 am-1:15 pm
1 stop5h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$175
TampaSt. Louis
TPA Tampa - STL Lambert-St Louis
TPASTL
Tampa
Thu 10/29
6:15 am-7:40 am
Nonstop2h 25m
Lambert-St Louis
Mon 11/2
5:00 am-8:20 am
Nonstop2h 20m
$257
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Tampa to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Tampa-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tampa-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tampa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Tampa with our price prediction graph.
TPA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to St. Louis
How far ahead should I book a flight from Tampa to St. Louis?
The price you pay for your flight from Tampa to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Tampa to St. Louis?
Currently, November is the cheapest month in which you can book a flight from Tampa to St. Louis (average of $296). Flying from Tampa to St. Louis in June is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to STL?
Find hourly flight availability from Tampa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 26, 2026.
It’s typically best to fly out from Tampa to St. Louis in the evening. Doing so could potentially save you 12% on the flight price compared to flying at noon, which is usually more expensive.
What is the cheapest day to fly from Tampa to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Tampa to St. Louis. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Tampa to St. Louis flight should consider departing on Friday afternoons when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Tampa to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Tampa to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 26, 2026.
Read reviews from past customers who have flown Southwest,Delta, andJetBlue from Tampa to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Tampa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Collinsville
Edwardsville
Glencoe
Chesterfield
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Top 5 airlines flying from Tampa to St. Louis
Discover the top 5 airlines that operate flights from Tampa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$199 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$155 | Average$317 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$175 | Average$329 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$455 | FlexibilityNo cancel fee | On-time63% |